Pain and aging: the emergence of a new subfield of pain research

Gagliese, Lucia

doi:10.1016/j.jpain.2008.10.013

Cited by 187Musculoskeletal pain and rehabilitationPain Management and Opioid UsePain Mechanisms and Treatments

Pain and aging: the emergence of a new subfield of pain research

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Gagliese, Lucia·2009·The Journal of Pain

DOI 10.1016/j.jpain.2008.10.013

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Abstract

Unlabelled The pain and aging subfield has grown dramatically, including a 6-fold increase in publications over the last 2 decades. This subfield is based on the assumption that pain in older and younger adults differs in clinically and theoretically significant ways. If this were not the case, data from younger groups could be generalized to older persons, and the subfield would not be needed. This article considers the evidence for this assumption. Possible interpretations of the discrepant findings of age-related increases, decreases and stability in pain, including methodological limitations, challenges of gerontological research, and the possibility of nonuniform age-related variation, are discussed. Evidence is presented for several unique characteristics of geriatric pain: difficulty using Visual Analog Scales, increased vulnerability to neuropathic pain, decreased vulnerability to acute pain related to visceral pathology, prolonged recovery from tissue and nerve injury, including prolonged hyperalgesia, and differences in the relationships among psychosocial factors important in adjustment to chronic pain. However, without a theoretical framework, it is difficult to integrate these results in a heuristic manner. Further research is needed to elucidate the characteristics of geriatric pain, to examine the mechanisms for age-related patterns, and to develop and test the efficacy of age-tailored interventions.Perspective This article reviews the emerging subfield of pain and aging, discusses the interpretation of age-related patterns in pain, and presents several avenues for future research and subfield development. This could contribute to the continued growth of this subfield.

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Impairments have been observed in late adulthood in perceiving other interoceptive signals, such as pain, temperature, hydration and taste.
“Impairments have also been observed in late adulthood in perceiving other interoceptive signals, such as pain, temperature, hydration and taste (Clark and Mehl, 1971; Gagliese, 2009; Silver, 1990; Stevens et al., 1995).”
From Atypical interoception as a common risk factor for psychopathology: A review (2021) · cites this paper as Gagliese, 2009
The Abstract reports decreased vulnerability in older adults to acute pain related to visceral pathology, supporting an age-related difference in some pain perception. It also describes increases, decreases and stability across different kinds of pain; it does not establish a general impairment in perceiving pain. The cited paper does not support the sentence’s claims about temperature, hydration or taste. (LLM, conf=0.86)
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Authors: Gagliese, L.
Affiliations: York University (CA)
Corresponding author: Gagliese, Lucia
ORCID: Gagliese, Lucia
Venue: The Journal of Pain
Publisher: Elsevier BV
Published: 2009-04
Volume: 10
Issue: 4
Pages: 343-353
ISSN: 1526-5900 (ISSN-L)
DOI: 10.1016/j.jpain.2008.10.013
OpenAlex: W2043293474
Cited by: 187
References: 127
Citations by year: 2026: 5 · 2025: 8 · 2024: 6 · 2023: 6 · 2022: 4 · 2021: 10 · 2020: 12 · 2019: 8 · 2018: 14 · 2017: 18 · 2016: 14 · 2015: 18 · 2014: 17 · 2013: 18 · 2012: 11
FWCI: 1.00
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 5276 d)
Locations: Journal of Pain (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
Health Sciences › Medicine › Physiology › Pain Mechanisms and Treatments
Keywords: geriatric pain, neuropathic pain, hyperalgesia, chronic pain, psychosocial factors in pain
MeSH terms: Aging, Chronic Disease, Humans, Pain, Pain Measurement, Research, Pain Threshold

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Pain and aging: the emergence of a new subfield of pain research

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