CoChat
Sign Up
Cited by 250Fibromyalgia and Chronic Fatigue Syndrome ResearchPain Mechanisms and TreatmentsMyofascial pain diagnosis and treatment

The DOI matches its Crossref record; 183 of the 187 references it cites were found in a registry or an index.

Understanding fibromyalgia: lessons from the broader pain research community.

Open access
Williams, David A., Clauw, Daniel J.·2009·The Journal of Pain
DOI 10.1016/j.jpain.2009.06.001PMC PMC2741022
Open this paper in CoChat — free accountOpen PDF

Abstract

Unlabelled Fibromyalgia (FM) is a chronic pain condition marked by centrally mediated augmentation of pain and sensory processes. Skepticism has marked the history of this condition, but more recent study has identified neurobiological underpinnings supporting many of the symptoms associated with this condition. Early research in FM had unprecedented latitude within the rheumatology community to borrow heavily from theory and methods being applied in chronic pain research more generally. These insights facilitated rapid advances in FM research, not the least of which was the abandonment of a peripheral focus in favor of studying central mechanisms associated with central augmentation. Currently, rapid-paced discovery is taking place in FM genetics, patient assessment, new therapeutic targets, and novel methods of treatment delivery. Such insights are not likely to be limited in application just to FM and could have relevance to the broader field of pain research as well.Perspective This manuscript reviews the history of FM and its diagnosis, evidence supporting central augmentation of pain in FM, potential mechanisms of central augmentation, current approaches to integrated care of FM, and areas of active collaboration between FM research and other chronic pain conditions.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.jpain.2009.06.001

Cites

183 of 183 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

3 retracted

Show all 187 references

Research works printed but not linked: 5

  1. Bradley, 1996, Abnormal brain regional cerebral blood flow and cerebrospinal fluid levels of Substance P in patients and non-patients with fibromyalgia, Arthritis Rheum, 39, 1109
  2. Mccarberg, 2002, The relationship between health locus of control and well-being in fibromyalgia patients, J Pain, 3, 14
  3. Staud, 2001, Repetitive muscle stimuli result in enhanced wind-up of fibromyalgia patients, Arthritis Rheum, 44
  4. Welin, 1995, Elevated Substance P levels are contrasted by a decrease in met-enkephalin-arg-phe levels in CSF from fibromyalgia patients, Journal of Musculoskeletal Pain, 3, 4
  5. Yunus, 1997, Positron Emission Tomography (PET) imaging of the brain in fibromyalgia syndrome (FMS), Arthritis Rheum, 40, S188

Cited by

Sorted by citations

Items 201–249 of 249

Related

See all

Metadata

Authors
Williams, D. A., & Clauw, D. J.
Affiliations
University of Michigan (US)
Corresponding author
Williams, David A.
ORCID
Venue
The Journal of Pain
Publisher
Elsevier BV
Published
2009-08
Volume
10
Issue
8
Pages
777-791
ISSN
1526-5900 (ISSN-L)
DOI
10.1016/j.jpain.2009.06.001
PMC
PMC2741022
OpenAlex
W2154974503
Cited by
250
References
187
Citations by year
2026: 7 · 2025: 4 · 2024: 7 · 2023: 9 · 2022: 19 · 2021: 13 · 2020: 5 · 2019: 10 · 2018: 11 · 2017: 14 · 2016: 17 · 2015: 20 · 2014: 24 · 2013: 23 · 2012: 23
FWCI
2.82
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Pain (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • U.S. Department of Defense (DAMD170020018)
  • National Institutes of Health
  • National Institute of Arthritis and Musculoskeletal and Skin Diseases (U01AR55069, AR053207, U01AR055069, R01AR053207, R01AR050044)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Fibromyalgia and Chronic Fatigue Syndrome Research
  • Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
  • Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Myofascial pain diagnosis and treatment
Keywords
fibromyalgia, chronic pain, central sensitization, central pain processing, neurobiological mechanisms, fibromyalgia diagnosis, therapeutic target, integrated care, interdisciplinary collaboration
MeSH terms
Brain, Fibromyalgia, Humans, Models, Neurological, Pain, Pain Management

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review