The DOI matches its Crossref record; 35 of the 37 references it cites were found in a registry or an index.
Cannabis Use in HIV for Pain and Other Medical Symptoms
Open accessAbstract
Despite the major benefits of antiretroviral therapy on survival during HIV infection, there is an increasing need to manage symptoms and side effects during long-term drug therapy. Cannabis has been reported anecdotally as being beneficial for a number of common symptoms and complications in HIV infections, for example, poor appetite and neuropathy. This study aimed to investigate symptom management with cannabis. Following Ethics Committee approval, HIV-positive individuals attending a large clinic were recruited into an anonymous cross-sectional questionnaire study. Up to one-third (27%, 143/523) reported using cannabis for treating symptoms. Patients reported improved appetite (97%), muscle pain (94%), nausea (93%), anxiety (93%), nerve pain (90%), depression (86%), and paresthesia (85%). Many cannabis users (47%) reported associated memory deterioration. Symptom control using cannabis is widespread in HIV outpatients. A large number of patients reported that cannabis improved symptom control.
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“Each study involved whole plant cannabis in inhaled or oral formats, with patients reporting moderate relief.”
From Clinical Practice Guidelines for Cannabis and Cannabinoid-Based Medicines in the Management of Chronic Pain and Co-Occurring Conditions (2024) · cites this paper as [88]
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“Three cross-sectional studies also report antidepressant effects of CBM.82,97,98”
From Clinical Practice Guidelines for Cannabis and Cannabinoid-Based Medicines in the Management of Chronic Pain and Co-Occurring Conditions (2024) · cites this paper as [97]
In the citing paper
“Among the symptoms improved following cannabis were appetite (97% reported improvement), pain (improved in 94% of the patients with pain), nausea (93% reported improvement) and anxiety (93% reported improvement).138”
From Cannabinoids as Pharmacotherapies for Neuropathic Pain: From the Bench to the Bedside (2009) · cites this paper as [138]
In the citing paper
“An anonymous cross-sectional questionnaire study revealed that as many as one-third of patients suffering from HIV have used cannabis to treat symptoms.138”
From Cannabinoids as Pharmacotherapies for Neuropathic Pain: From the Bench to the Bedside (2009) · cites this paper as [138]
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Citations
Cites
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Items 201–209 of 209
From relief to risks: a comprehensive review of medical cannabis
Lokhande, N., Mokal, A., Deshmukh, N. N., Borkar, A., & Patil, S. (2025) · International Journal of Community Medicine and Public Health · doi:10.18203/2394-6040.ijcmph20251740
Qrareya, A. N., Moss, E. M., Mahdi, F., Salahuddin, M., Hu, D., Leon, M. A. D., Wanas, A. S., Radwan, M. M., ElSohly, M. A., Ashpole, N. M., et al. (2025) · NeuroImmune Pharmacology and Therapeutics · doi:10.1515/nipt-2024-0025
Awad, J., Sun, W., Maria, D. S., Schnall, R., Apiruknapanond, P., Wang, T., Valencia, C. P., Davey, C. H., Solís-Báez, S. S., Iwu, E., et al. (2026) · AIDS and Behavior · doi:10.1007/s10461-025-04944-z
Neuropathic pain and depression : molecular alterations in the anterior cingulate cortex
Humo, M. (2019) · theses.fr (ABES) · doi:10.70675/e72f9364z66cbz45c4z8b42zb7f3564cd3d0
Couton, C., Wanneveich, M., Dieuleveult, B. D., Robin, C., Ayena, K., Harry, A., Klein, H., Avettand-Fènoël, V., Hocqueloux, L., Mollet, L., et al. (2026) · Cannabis and Cannabinoid Research · doi:10.1177/25785125261439014
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Non-pharmacologic approaches to managing chronic pain in persons living with HIV: a scoping review
Kietrys, D. M., Parrott, J. S., Mittal, R., Spinelli, B. A., Campione, E., Galantino, M. L., Vader, K., Ghajar, M., Dreker, M. R., O’Brien, K. K., et al. (2026) · Journal of Public Health · doi:10.1007/s10389-026-02830-z
Abdallah, K., & Yalçın, İ. (2025) · Dunod eBooks · doi:10.3917/dunod.poisb.2025.01.0841
Metadata
- Authors
- Woolridge, E., Barton, S., Samuel, J., Osorio, J., Dougherty, A., & Holdcroft, A.
- Affiliations
- Imperial College London (GB)
- Chelsea and Westminster Hospital (GB)
- Chelsea and Westminster Hospital NHS Foundation Trust (GB)
- ORCID
- Barton, Simon
- Venue
- Journal of Pain and Symptom Management
- Publisher
- Elsevier BV
- Published
- 2005-04
- Volume
- 29
- Issue
- 4
- Pages
- 358-367
- ISSN
- 0885-3924 (ISSN-L)
- OpenAlex
- W2115233771
- Cited by
- 208
- References
- 37
- Citations by year
- 2026: 6 · 2025: 5 · 2024: 4 · 2023: 21 · 2022: 12 · 2021: 18 · 2020: 5 · 2019: 11 · 2018: 8 · 2017: 10 · 2016: 9 · 2015: 15 · 2014: 11 · 2013: 7 · 2012: 9
- FWCI
- 6.17
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Pain and Symptom Management (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Cannabis and Cannabinoid Research
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS drug development and treatment
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Keywords
- cannabis use, HIV infection, symptom management, neuropathic pain, neuropathy, appetite, nausea, anxiety, depression, paresthesia, antiretroviral therapy adverse effects, memory impairment
- MeSH terms
- Adult, Aged, Cannabinoids, Cannabis, Cross-Sectional Studies, Data Collection, Drug Therapy, Female, United Kingdom, Humans, Male, Phytotherapy, Middle Aged, Nausea, Pain, Severity of Illness Index, HIV Infections, Comorbidity, Plant Preparations
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