Cited by 1,191Palliative Care and End-of-Life IssuesPalliative and Oncologic CarePain Management and Opioid Use

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A Comparison of Symptom Prevalence in Far Advanced Cancer, AIDS, Heart Disease, Chronic Obstructive Pulmonary Disease and Renal Disease

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Solano, Joao Paulo, Gomes, Barbara, Higginson, Irene J.·2006·Journal of Pain and Symptom Management

DOI 10.1016/j.jpainsymman.2005.06.007

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Abstract

Little attention has been paid to the symptom management needs of patients with life-threatening diseases other than cancer. In this study, we aimed to determine to what extent patients with progressive chronic diseases have similar symptom profiles. A systematic search of medical databases (MEDLINE, EMBASE, and PsycINFO) and textbooks identified 64 original studies reporting the prevalence of 11 common symptoms among end-stage patients with cancer, acquired immunodeficiency syndrome (AIDS), heart disease, chronic obstructive pulmonary disease, or renal disease. Analyzing the data in a comparative table (a grid), we found that the prevalence of the 11 symptoms was often widely but homogeneously spread across the five diseases. Three symptoms-pain, breathlessness, and fatigue-were found among more than 50% of patients, for all five diseases. There appears to be a common pathway toward death for malignant and nonmalignant diseases. The designs of symptom prevalence studies need to be improved because of methodological disparities in symptom assessment and designs.

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Authors: Solano, J. P., Gomes, B., & Higginson, I. J.
Affiliations: King's College London (GB)
Corresponding author: Higginson, Irene J.
ORCID: Higginson, Irene J.
Venue: Journal of Pain and Symptom Management
Publisher: Elsevier BV
Published: 2006-01
Volume: 31
Issue: 1
Pages: 58-69
ISSN: 0885-3924 (ISSN-L)
DOI: 10.1016/j.jpainsymman.2005.06.007
OpenAlex: W2144048086
Cited by: 1,191
References: 126
Citations by year: 2026: 26 · 2025: 49 · 2024: 52 · 2023: 52 · 2022: 51 · 2021: 67 · 2020: 79 · 2019: 67 · 2018: 72 · 2017: 84 · 2016: 75 · 2015: 77 · 2014: 65 · 2013: 60 · 2012: 74
FWCI: 39.35
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 5125 d)
Locations: Journal of Pain and Symptom Management (publishedVersion)
PubMed (publishedVersion)
Research Portal (King's College London) (submittedVersion)
LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (submittedVersion, other-oa)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative and Oncologic Care
Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
Keywords: symptom prevalence, symptom management, cancer, AIDS, heart disease, chronic obstructive pulmonary disease, kidney disease, pain, dyspnea, fatigue, symptom assessment
MeSH terms: Acquired Immunodeficiency Syndrome, Aged, Aged, 80 and over, Depression, Female, Heart Diseases, Humans, Kidney Diseases, Male, Middle Aged, Neoplasms, Palliative Care, Pulmonary Disease, Chronic Obstructive

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A Comparison of Symptom Prevalence in Far Advanced Cancer, AIDS, Heart Disease, Chronic Obstructive Pulmonary Disease and Renal Disease

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