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Cited by 23Celiac Disease Research and ManagementGastrointestinal motility and disordersGut microbiota and health

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Abdominal Pain-Associated Functional Gastrointestinal Disorder Prevalence in Children and Adolescents with Celiac Disease on Gluten-Free Diet: A Multinational Study

Saps, Miguel, Sansotta, Naire, Bingham, Sean, Magazzu, Giuseppe, Grosso, Caterina, Romano, Simone, Pusatcioglu, Cenk, Guandalini, Stefano·2017·The Journal of Pediatrics
DOI 10.1016/j.jpeds.2016.11.049
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Abstract

Objective To test the hypothesis that children with celiac disease (CD) on gluten-free diet are at increased risk of abdominal pain (AP) associated-functional gastrointestinal disorders (FGIDs). Study design This was a multinational cross-sectional study performed from 2014 to 2015. Patients 4-18 years of age with CD on gluten-free diet for longer than 6 months were recruited from pediatric CD clinics in US and Italy. Control groups included siblings of children with CD (with normal tissue transglutaminase levels) and unrelated controls. Subjects or parents completed the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III. Results Children (n = 289) were recruited (55% US, 45% Italy): 96 children with CD, 96 sibling controls, and 97 unrelated controls. Chronic AP was present in 30 (30.9%) subjects with CD, 22 (22.7%) sibling controls, and 21 (21.6%) unrelated controls (P = .26 patients with CD vs siblings; P = .18 patients with CD vs unrelated; P = .96 siblings vs unrelated). AP-FGIDs were present in 8 (8.2%) subjects with CD, 8 (8.2%) sibling controls, and 2 (2.1%) unrelated controls (P = 1.00 subjects with CD vs sibling controls; P = .06 subjects with CD vs unrelated controls; P = .06 sibling controls vs unrelated controls). Conclusion This multinational study evaluated the prevalence of chronic abdominal pain and AP-FGIDs in the pediatric population with CD. We found that subjects with CD and controls have a similar prevalence of chronic AP and AP-FGIDs. This sug…

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  • Similar prevalence of abdominal pain and functional gastrointestinal disorders has been demonstrated in celiac disease patients on a gluten-free diet for at least six months versus controls on a regular diet.

    “Similar prevalence of abdominal pain and functional gastrointestinal disorders have been demonstrated in CD on a GFD for at least six months vs. controls on a regular diet (66).”

    From ESPGHAN Position Paper on Management and Follow-up of Children and Adolescents With Celiac Disease. (2022) · cites this paper as [66]

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Research works printed but not linked: 37

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Metadata

Authors
Saps, M., Sansotta, N., Bingham, S., Magazzu, G., Grosso, C., Romano, S., Pusatcioglu, C., & Guandalini, S.
Affiliations
  • Nationwide Children's Hospital (US)
  • University of Verona (IT)
  • University of Messina (IT)
  • Lurie Children's Hospital (US)
  • University of Chicago (US)
Corresponding author
Bingham, Sean
ORCID
Venue
The Journal of Pediatrics
Publisher
Elsevier BV
Published
2017-03
Volume
182
Pages
150-154
ISSN
0022-3476 (ISSN-L)
DOI
10.1016/j.jpeds.2016.11.049
OpenAlex
W2563163803
Cited by
23
References
4
Citations by year
2026: 1 · 2025: 2 · 2024: 1 · 2022: 3 · 2021: 3 · 2020: 5 · 2019: 2 · 2018: 4 · 2017: 2
FWCI
2.91
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • The Journal of Pediatrics (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Gastroenterology › Celiac Disease Research and Management
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Keywords
celiac disease, gluten-free diet, abdominal pain, functional gastrointestinal disorders, chronic abdominal pain, pediatric celiac disease, prevalence, gastrointestinal inflammation, Rome III questionnaire
MeSH terms
Adolescent, Celiac Disease, Child, Child, Preschool, Cross-Sectional Studies, Female, Gastrointestinal Diseases, Humans, Male, Prognosis, Reference Values, Severity of Illness Index, Cohort Studies, Abdominal Pain, Comorbidity, Prevalence, Age Distribution, Sex Distribution, Risk Assessment, Internationality, Diet, Gluten-Free

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