Cited by 374Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMental Health Treatment and AccessMaternal Mental Health During Pregnancy and Postpartum

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The Hospital Anxiety and Depression Scale: A diagnostic meta-analysis of case-finding ability

Brennan, Cathy, Worrall-Davies, Anne, McMillan, Dean, Gilbody, Simon, House, Allan·2010·Journal of Psychosomatic Research

DOI 10.1016/j.jpsychores.2010.04.006

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Abstract

Objective To quantify the accuracy of the Hospital Anxiety and Depression Scale (HADS) as a case-finding instrument for anxiety and depressive disorders.Method MEDLINE, PSYCHINFO, EMBASE, CINAHL, BNI, and AMED were searched from January 1983 to June 2006. Studies were included that administered the HADS, used a standardized psychiatric interview to establish a diagnosis of anxiety or depression, and provided sufficient data on sensitivity and specificity (N=41). Summary sensitivity, specificity, likelihood ratios, and diagnostic odds ratios were calculated for each study. Random effects meta-analytic pooling across studies at the recommended clinical (7/8) and research (10/11) cutoff points was undertaken and summary receiver operating characteristic curves constructed.Results For major depressive disorders, a cut point of ≥8 gave a sensitivity of 0.82 (95% CI, 0.73-0.89) and a specificity of 0.74 (95% CI, 0.60-0.84) and a cut point ≥11 gave a sensitivity of 0.56 (95% CI, 0.40-0.71) and a specificity of 0.92 (95% CI, 0.79-0.97).Conclusions Many studies have shown that the HADS is a useful screening tool to identify emotional distress in nonpsychiatric patients. However, it does not appear to be superior to other screening instruments in terms of identifying specific mental disorders in physical health settings.

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Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722
The Hospital Anxiety and Depression Scale
Zigmond, A. S., & Snaith, R. P. (1983) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1983.tb09716.x · Cited by 47,139
Lifetime and 12-Month Prevalence of DSM-III-R Psychiatric Disorders in the United States: Results From the National Comorbidity Survey
Kessler, R. C. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950010008002 · Cited by 12,370
The validity of the Hospital Anxiety and Depression Scale
Bjelland, I., Dahl, A. A., Haug, T. T., & Neckelmann, D. (2002) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(01)00296-3 · Cited by 9,779
Anxiety disorders in primary care: prevalence, impairment, comorbidity, and detection
Kroenke, K., Spitzer, R. L., Williams, J. B. W., Monahan, P. O., & Löwe, B. (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-146-5-200703060-00004 · Cited by 4,741
Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study
Murray, C. J., & Lopez, A. D. (1997) · The Lancet · doi:10.1016/s0140-6736(96)07495-8 · Cited by 4,492 · cited 1×
“Depressive disorders are common [1–4] and a leading cause of disability worldwide [5,6].”
Background
The Structured Clinical Interview for DSM-III-R (SCID): I: History, Rationale, and Description
Spitzer, R. L. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820080032005 · Cited by 4,336
The Handbook of Research Synthesis.
Howel, D., Cooper, H., & Hedges, L. V. (1995) · Biometrics · doi:10.2307/2533295 · Cited by 3,657
Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews
Reitsma, J. B., Glas, A. S., Rutjes, A. W. S., Scholten, R. J. P. M., Bossuyt, P. M., & Zwinderman, A. H. (2005) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2005.02.022 · Cited by 3,369 · cited 2×
“Summary ROC (sROC) curves [16] were then constructed using the bivariate model to produce a 95% confidence ellipse within ROC space [14].”
Method

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Pinakhina, D. V., Yermakovich, D., Vergasova, E., Kasyanov, E. D., Rukavishnikov, G. V., Rezapova, V., Kolosov, N., Sergushichev, A., Popov, I., Kovalenko, E. V., et al. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2022.972196 · Cited by 13
Longitudinal modelling of theory-based depressive vulnerabilities, depression trajectories and poor outcomes post-ACS.
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Authors: Brennan, C., Worrall-Davies, A., McMillan, D., Gilbody, S., & House, A.
Affiliations: University of Leeds (GB)
Corresponding author: Brennan, Cathy
ORCID: Brennan, Cathy
McMillan, Dean
Gilbody, Simon
House, Allan
Venue: Journal of Psychosomatic Research
Publisher: Elsevier BV
Published: 2010-10
Volume: 69
Issue: 4
Pages: 371-378
ISSN: 0022-3999 (ISSN-L)
DOI: 10.1016/j.jpsychores.2010.04.006
OpenAlex: W2017953368
Cited by: 374
References: 54
Citations by year: 2026: 22 · 2025: 22 · 2024: 34 · 2023: 23 · 2022: 34 · 2021: 33 · 2020: 36 · 2019: 23 · 2018: 21 · 2017: 26 · 2016: 17 · 2015: 21 · 2014: 13 · 2013: 21 · 2012: 19
FWCI: 1.91
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Journal of Psychosomatic Research (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
Keywords: Hospital Anxiety and Depression Scale, anxiety disorders, depressive disorders, case finding, screening accuracy, sensitivity and specificity, diagnostic odds ratio, likelihood ratios, receiver operating characteristic, cut-off values
MeSH terms: Anxiety, Anxiety Disorders, Depression, Depressive Disorder, Humans, Predictive Value of Tests, Psychiatric Status Rating Scales, Sensitivity and Specificity, Odds Ratio

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The Hospital Anxiety and Depression Scale: A diagnostic meta-analysis of case-finding ability

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