Psychometric evaluation of the Amphetamine Cessation Symptom Assessment
Abstract
Testing of a new scale, the Amphetamine Cessation Symptom Assessment (ACSA), in a sample of treatment-seeking amphetamine users (N = 133) showed satisfactory reliability, while factor analysis identified three components explaining 64.7% of the variance in scores. Scores were inversely related to subjective general well-being (r = -.33, p < .01) and directly related to the Beck Depression Inventory (r = .59, p < .01). There were positive relationships between the ACSA and measures of amphetamine dependence (r = .36, p < .01) and the intensity of recent amphetamine use (r = .24, p < .01). The ACSA discriminated between "low-dose" and "high-dose" users, indicating discriminant validity. In inpatients (n = 63), ACSA scores declined significantly over time, while higher scores in inpatient treatment dropouts indicated predictive validity. The ACSA showed satisfactory reliability and validity, with a three-factor solution providing the best fit to the data. The ACSA could play an important role in providing clinical outcome data, particularly in outcome evaluation of new treatment protocols.
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The ACSA is a self-completed questionnaire with 16 items rated on 5-point scales (0-4), total score 0-64.
“The ACSA, a self-completed questionnaire, contains 16 items rated on 5-point scales (0 [not at all] to 4 [extremely]); total score ranges from 0–64 (McGregor et al, 2008).”
From Lisdexamfetamine Dimesylate for Adults with Moderate to Severe Binge Eating Disorder: Results of Two Pivotal Phase 3 Randomized Controlled Trials (2016) · cites this paper as McGregor et al, 2008
The Amphetamine Cessation Symptom Assessment is a validated self-report with 16 items.
“The Amphetamine Cessation Symptom Assessment (ACSA; measured at baseline and weeks 10-11 (single-blind stage)) is a validated self-report with 16 items rated from 0 (not at all) to 4 (extremely) (McGregor et al, 2008).”
From Lisdexamfetamine Dimesylate Augmentation in Adults With Persistent Executive Dysfunction After Partial or Full Remission of Major Depressive Disorder (2014) · cites this paper as McGregor et al, 2008
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- Authors
- McGregor, C., Srisurapanont, M., Mitchell, A., Longo, M. C., Cahill, S., & White, J. M.
- Affiliations
- Government of Western Australia Department of Health (AU)
- Chiang Mai University (TH)
- The University of Adelaide (AU)
- Venue
- Journal of Substance Abuse Treatment
- Publisher
- Elsevier BV
- Published
- 2008-06
- Volume
- 34
- Issue
- 4
- Pages
- 443-449
- ISSN
- 0740-5472 (ISSN-L)
- OpenAlex
- W2107194409
- Cited by
- 47
- References
- 23
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 1 · 2023: 3 · 2022: 5 · 2021: 2 · 2019: 2 · 2018: 3 · 2017: 2 · 2016: 1 · 2015: 1 · 2014: 2 · 2013: 2 · 2012: 1
- FWCI
- 2.75
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Substance Abuse Treatment (publishedVersion)
- PubMed (publishedVersion)
- Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
- Funders
- Government of South Australia
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Social Sciences › Decision Sciences › Management Science and Operations Research › Psychometric Methodologies and Testing
- Keywords
- amphetamine dependence, withdrawal symptoms, scale validation, psychometric properties, depression, well-being, treatment discontinuation, inpatient care, treatment outcome assessment
- MeSH terms
- Adult, Amphetamine, Factor Analysis, Statistical, Female, Humans, Male, Psychometrics, Surveys and Questionnaires, Reproducibility of Results, Substance-Related Disorders, Diagnostic and Statistical Manual of Mental Disorders
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