The DOI matches its Crossref record; 47 of the 49 references it cites were found in a registry or an index.
Opioid overdose prevention with intranasal naloxone among people who take methadone
Abstract
Overdose education and naloxone distribution (OEND) is an intervention that addresses overdose, but has not been studied among people who take methadone, a drug involved in increasing numbers of overdoses. This study describes the implementation of OEND among people taking methadone in the previous 30 days in various settings in Massachusetts. From 2008 to 2010, 1553 participants received OEND who had taken methadone in the past 30 days. Settings included inpatient detoxification (47%), HIV prevention programs (25%), methadone maintenance treatment programs (MMTP) (17%), and other settings (11%). Previous overdose, recent inpatient detoxification and incarceration, and polysubstance use were overdose risks factors common among all groups. Participants reported 92 overdose rescues. OEND programs are public health interventions that address overdose risk among people who take methadone and their social networks. OEND programs can be implemented in MMTPs, detoxification programs, and HIV prevention programs.
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Metadata
- Authors
- Walley, A. Y., Doe-Simkins, M., Quinn, E., Pierce, C., Xuan, Z., & Ozonoff, A.
- Affiliations
- Boston University (US)
- Boston Children's Hospital (US)
- Venue
- Journal of Substance Abuse Treatment
- Publisher
- Elsevier BV
- Published
- 2013-02
- Volume
- 44
- Issue
- 2
- Pages
- 241-247
- ISSN
- 0740-5472 (ISSN-L)
- OpenAlex
- W1979851403
- Cited by
- 107
- References
- 49
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 4 · 2023: 8 · 2022: 7 · 2021: 7 · 2020: 8 · 2019: 11 · 2018: 6 · 2017: 11 · 2016: 16 · 2015: 13 · 2014: 10 · 2013: 3
- FWCI
- 8.03
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Substance Abuse Treatment (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Centers for Disease Control and Prevention (1R21CE001602-02)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
- Keywords
- opioid overdose prevention, intranasal naloxone, overdose education and naloxone distribution, methadone maintenance treatment, opioid use disorder, overdose risk factors, inpatient detoxification, HIV prevention programs, polydrug use, prison history, public health interventions
- MeSH terms
- Administration, Intranasal, Adult, Female, Humans, Male, Massachusetts, Methadone, Middle Aged, Naloxone, Narcotic Antagonists, Opioid-Related Disorders, Narcotics, Patient Education as Topic, Pilot Projects, Risk Factors, Substance Withdrawal Syndrome, HIV Infections, Young Adult, Opiate Substitution Treatment, Drug Overdose
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