The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Transient amorphous calcium phosphate in forming enamel
Open accessAbstract
Enamel, the hardest tissue in the body, begins as a three-dimensional network of nanometer size mineral particles, suspended in a protein gel. This mineral network serves as a template for mature enamel formation. To further understand the mechanisms of enamel formation we characterized the forming enamel mineral at an early secretory stage using x-ray absorption near-edge structure (XANES) spectromicroscopy, transmission electron microscopy (TEM), FTIR microspectroscopy and polarized light microscopy. We show that the newly formed enamel mineral is amorphous calcium phosphate (ACP), which eventually transforms into apatitic crystals. Interestingly, the size, shape and spatial organization of these amorphous mineral particles and older crystals are essentially the same, indicating that the mineral morphology and organization in enamel is determined prior to its crystallization. Mineralization via transient amorphous phases has been previously reported in chiton teeth, mollusk shells, echinoderm spicules and spines, and recent reports strongly suggest the presence transient amorphous mineral in forming vertebrate bones. The present finding of transient ACP in murine tooth enamel suggests that this strategy might be universal.
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Cites
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Cited by
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De Yoreo, J. J., Gilbert, P. U. P. A., Sommerdijk, N. A. J. M., Penn, R. L., Whitelam, S., Joester, D., Zhang, H., Rimer, J. D., Navrotsky, A., Banfield, J. F., et al. (2015) · Science · doi:10.1126/science.aaa6760 · Cited by 2,137
Self-citationAmorphous calcium (ortho)phosphates
Dorozhkin, S. V. (2010) · Acta Biomaterialia · doi:10.1016/j.actbio.2010.06.031 · Cited by 485
Hierarchical Structures of Bone and Bioinspired Bone Tissue Engineering
Liu, Y., Luo, D., & Wang, T. (2016) · Small · doi:10.1002/smll.201600626 · Cited by 482
Mahamid, J., Aichmayer, B., Shimoni, E., Ziblat, R., Li, C., Siegel, S., Paris, O., Fratzl, P., Weiner, S., & Addadi, L. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0914218107 · Cited by 452
Phase transitions in biogenic amorphous calcium carbonate
Gong, Y. U. T., Killian, C. E., Olson, I. C., Appathurai, N. P., Amasino, A. L., Martin, M. C., Holt, L. J., Wilt, F. H., & Gilbert, P. U. P. A. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1118085109 · Cited by 304
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Metadata
- Authors
- Beniash, E., Metzler, R. A., Lam, R. S. K., & Gilbert, P. U. P. A.
- Venue
- Journal of Structural Biology
- Publisher
- Elsevier BV
- Published
- 2009-05
- Volume
- 166
- Issue
- 2
- Pages
- 133-143
- ISSN
- 1047-8477 (ISSN-L)
- OpenAlex
- W2109207624
- Cited by
- 444
- References
- 47
- FWCI
- 15.85
- Type
- journal article
- Language
- en
- Open access
- green
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