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Synthesis and estrogenic activity of BODIPY-labeled estradiol conjugates

Peřina, M., Börzsei, R., Ágoston, H., Hlogyik, T., Poór, M., Laczkó-Rigó, R., Özvegy‐Laczka, C., Batta, G., Hetényi, C., Vojáčková, V., et al. (2024) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2024.106813 · Cited by 4

Chemical synthesis of C3-oxiranyl/oxiranylmethyl-estrane derivatives targeted by molecular modeling and tested as potential inhibitors of 17β-hydroxysteroid dehydrogenase type 1

Lespérance, M., Barbeau, X., Roy, J., Maltais, R., Lagüe, P., & Poirier, D. (2018) · Steroids · doi:10.1016/j.steroids.2018.09.009 · Cited by 4

Synthesis and preliminary evaluation of a modified estradiol-core bearing a fused γ-lactone as non-estrogenic inhibitor of 17β-hydroxysteroid dehydrogenase type 1

Ouellet, É., Ayan, D. P., & Poirier, D. (2011) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2011.06.110 · Cited by 4

Female Adipose Tissue Sex Steroid Biosynthesis

Hetemäki, N., Mikkola, T. S., & Savolainen-Peltonen, H. M. (2025) · Seminars in Reproductive Medicine · doi:10.1055/s-0045-1811952 · Cited by 5

Suppressed estrogen supply via extra-ovarian progesterone receptor membrane component 1 in menopause

Lee, S. R., Yang, H. J., Jo, S. L., Lee, Y. H., Lee, H. W., Park, B.-K., & Hong, E. (2021) · Journal of Biomedical Research · doi:10.7555/jbr.35.20200172 · Cited by 3

Drug targets regulate systemic metabolism and provide new horizons to treat nonalcoholic steatohepatitis

Wang, Y., Yu, H., Cen, Z., Zhu, Y., & Wu, W. (2023) · Metabolism Open · doi:10.1016/j.metop.2023.100267 · Cited by 3

Intracrine oestrogen production and action in breast cancer: An epigenetic focus

Knower, K. C., To, S. Q., & Clyne, C. D. (2013) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2013.01.009 · Cited by 3

Identification of a First Enzymatic Activator of a 17β-Hydroxysteroid Dehydrogenase

Trottier, A., Maltais, R., & Poirier, D. (2014) · ACS Chemical Biology · doi:10.1021/cb500109e · Cited by 3

Redox homeostasis in ferroptosis and aging: a causal role for fard-1 and dhs-25 in Caenorhabditis elegans

Pensotti, R., Sciandrone, B., Bovio, F., Schröter, L., Maglioni, S., Thewes, L., Forcella, M. E., Rossi, A., Fusi, P. A., Berndt, C., et al. (2025) · Redox Biology · doi:10.1016/j.redox.2025.103912 · Cited by 2

Chemical synthesis, characterisation and biological evaluation of lactonic-estradiol derivatives as inhibitors of 17β-hydroxysteroid dehydrogenase type 1

Farhane, S., Fournier, M.-A., & Poirier, D. (2013) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2013.05.002 · Cited by 2

Epigenetic regulation of steroidogenic enzymes expressed in peripheral blood mononuclear cells from healthy individuals and from patients with chronic lymphocytic leukemia

Gaydou, L., Rossetti, M. F., Tschopp, M. V., Stoker, C., Bosquiazzo, V. L., & Ramos, J. G. (2020) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2020.105767 · Cited by 2

A larval ceRNA network centered on the lnc1778–miR-381-y–HSD17B8 axis regulates sex steroid hormone metabolism in Eriocheir sinensis

Zhao, F., Shi, Y., Kong, X., Zhang, K., Zhang, C., Yin, S., & Ning, X. (2026) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2026.106979 · Cited by 1

Hepatic HSD17B6 is dispensable for diet-induced fatty liver disease in mice

Yuan, D., Bai, N., Zhu, Q., Song, S., He, A., Wang, J., & Chen, Y. (2025) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2025.101924 · Cited by 1

Direct antiproliferative effect of nonsteroidal 17β-hydroxysteroid dehydrogenase type 1 inhibitors in vitro

Berényi, Á., Frotscher, M., Marchais‐Oberwinkler, S., Hartmann, R. W., Minorics, R., Ocsovszki, I., Falkay, G., & Zupkó, I. (2012) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.3109/14756366.2012.672414 · Cited by 1

The effects of dexamethasone on 17β-HSD1 levels at the rat optic nerve

Liu, C., Xu, G., Gong, P., & Wang, Z. (2019) · Technology and Health Care · doi:10.3233/thc-199033 · Cited by 1

Description of Chemical Synthesis, Nuclear Magnetic Resonance Characterization and Biological Activity of Estrane-Based Inhibitors/Activators of Steroidogenesis

Poirier, D. (2023) · Molecules · doi:10.3390/molecules28083499 · Cited by 1

Phenotypic Screening Coupled with AI-Driven Target Deconvolution Identifies α-Terthienyl as a Dual DPP-IV/HSD17β13 Modulator with Efficacy in a Mouse Model of MASLDPreprint

Hoegeman, K. M., Wotring, J. W., Fursmidt, R. M., Gaetz, J., Khalil, E. M., Selinger, D. W., Kovalenko, I., Schultz, T. L., McCarty, S. M., O’Meara, M. J., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.12.693988 · Cited by 1

Development of potent and selective inhibitors of 17β-hydroxysteroid dehydrogenase type 2 : a new target for the treatment of osteoporosis

Wetzel, M. (2011) · Publications of the UdS (Saarland University) · doi:10.22028/d291-22814

QSAR Analysis of 3- and 4-substituted 7-hydroxycoumarins as Novel 17?-HSD3 Inhibitors

Sharma, M. C. (2015) · Chemotherapy Open access · doi:10.4172/2167-7700.1000148

Évaluation biologique in vitro d'inhibiteurs de la stéroïde sulfatase ayant un effet SERM

Ouellet, C. (2013) · Corpus Université Laval (Université Laval)

A Sequential Dual Cleavage of the Arylsulfamate Linker to Provide Both Sulfamate and Phenol Derivatives

Fournier, D., Ciobanu, L. C., & Poirier, D. (2015) · Chemistry Journal of Moldova · doi:10.19261/cjm.2015.10(2).09

Adrenalectomy and Glucocorticoid Effects on the Rat Hepatic Aryl Hydrocarbon Receptor Pathway and the Response to Aromatic Hydrocarbons

Grey, A. M. (2012) · TSpace (University of Toronto)

Defining the role(s) of non-classical tumour suppressor Wwox in cellular function using Drosophila melanogaster genetic modelling

Choo, A. (2017) · Adelaide Research & Scholarship (AR&S) (University of Adelaide) · doi:10.4225/55/5850cd986b1cb

Synthèse de dérivés stéroïdiens et non stéroïdiens comme inhibiteurs des 17b-hydroxystéroïdes déshydrogénases type 1 et type 3

Djigoué, G. B. (2014) · Corpus Université Laval (Université Laval)

Identification and characterization of novel drugs for the treatment of pediatric gliomas

Ajeawung, N. F. (2014) · Corpus Université Laval (Université Laval)

Synthesis of monosaccharide and nucleoside conjugates of estrone derivatives

Bodnár, B. (2018) · doi:10.14232/phd.9761

Mechanisms of Fibrogenesis in NASH

Pastore, M., Gentilini, A., & Marra, F. (2020) · Springer eBooks · doi:10.1007/978-3-319-95828-6_6

Exploring the Molecular Mechanisms of 17β-HSD5-induced Carcinogenicity of Catha edulis via Molecular Modeling Approach

Saeed, M., Ashraf, S., Al-Sanosi, R. M., Alhazmi, H. A., Albratty, M., Najmi, A., Khalid, A., & Ul‐Haq, Z. (2020) · Medicinal Chemistry · doi:10.2174/1573406416666201005142522

Design and validation of specific inhibitors of 17 -hydroxysteroid dehydrogenases for therapeutic application in breast and prostate cancer, and in endometriosis

Day, J. M., Tutill, H. J., Purohit, A., & Reed, M. J. (2008) · Endocrine Related Cancer · doi:10.1677/erc-08-0042 · Cited by 123

Advances in Development of Inhibitors of 17β-Hydroxysteroid Dehydrogenases

Poirier, D. (2009) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/187152009788680000 · Cited by 57

Inhibitors of 17β-Hydroxysteroid Dehydrogenases

Poirier, D. (2003) · Current Medicinal Chemistry · doi:10.2174/0929867033368222 · Cited by 177

Recent advances in the development of 17beta-hydroxysteroid dehydrogenase inhibitors

Poirier, D. (2024) · Steroids · doi:10.1016/j.steroids.2024.109529 · Cited by 12

Contribution to the development of inhibitors of 17β-hydroxysteroid dehydrogenase types 1 and 7: Key tools for studying and treating estrogen-dependent diseases

Poirier, D. (2010) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2010.12.007 · Cited by 44