The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Vitamin D production in UK Caucasian and South Asian women following UVR exposure
Abstract
Background It is known that skin pigmentation reduces the penetration of ultraviolet radiation (UVR) and thus photosynthesis of 25-hydroxvitamin D (25(OH)D). However ethnic differences in 25(OH)D production remain to be elucidated. Objective The aim of this study was to investigate differences in vitamin D production between UK South Asian and Caucasian postmenopausal women, in response to a defined and controlled exposure to UVR. Design Seventeen women; 9 white Caucasian (skin phototype II and III), 8 South Asian women (skin phototype IV and V) participated in the study, acting as their own controls. Three blood samples were taken for the measurement of vitamin D status during the run in period (9days, no sunbed exposure) after which, all subjects underwent an identical UVR exposure protocol irrespective of skin colour (9 days, 3 sun bed sessions, 6, 8 and 8min respectively with approximately 80% body surface exposed). Skin tone was measured four times during the study. Results Despite consistently lower 25(OH)D levels in South Asian women, they were shown to synthesise vitamin D as efficiently as Caucasians when exposed to the same dose of UVR. Interestingly, the baseline level of vitamin D rather than ethnicity and skin tone influenced the amount of vitamin D synthesised. Conclusions This study have found no ethnic differences in the synthesis of 25(OH)D, possibly due to the baseline differences in 25(OH)D concentration or due to the small population size used in this stud…
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“Hakim et al. (2016) also found no differences in photosynthesis of calcidiol in different skin phototypes.”
From The evolution of human skin pigmentation: A changing medley of vitamins, genetic variability, and UV radiation during human expansion (2023) · cites this paper as Hakim et al., 2016
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Is the action spectrum for the UV-induced production of previtamin D3 in human skin correct?
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UVB therapy increases 25(OH) vitamin D syntheses in postmenopausal women with psoriasis
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A population-based cohort study on sun habits and endometrial cancer
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Cited by
Lucock, M. D. (2023) · American Journal of Biological Anthropology · doi:10.1002/ajpa.24564 · Cited by 35
Metadata
- Authors
- Hakim, O. A., Hart, K., McCabe, P., Berry, J., Francesca, R., Rhodes, L. E., Spyrou, N., Alfuraih, A., & Lanham-New, S.
- Venue
- The Journal of Steroid Biochemistry and Molecular Biology
- Publisher
- Elsevier BV
- Published
- 2016-11
- Volume
- 164
- Pages
- 223-229
- ISSN
- 0960-0760
- Cited by
- 23
- References
- 23
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- Funders
- King AbdulAziz University, Saudi Arabia
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.