Prediction of total healthcare cost following total shoulder arthroplasty utilizing machine learning
Abstract
Background Given the increase in demand in treatment of glenohumeral arthritis with anatomic total (aTSA) and reverse shoulder arthroplasty (RTSA), it is imperative to improve quality of patient care while controlling costs as private and federal insurers continue its gradual transition toward bundled payment models. Big data analytics with machine learning shows promise in predicting health care costs. This is significant as cost prediction may help control cost by enabling health care systems to appropriately allocate resources that help mitigate the cause of increased cost.Methods The Nationwide Readmissions Database (NRD) was accessed in 2018. The database was queried for all primary aTSA and RTSA by International Classification of Diseases, Tenth Revision (ICD-10) procedure codes: 0RRJ0JZ and 0RRK0JZ for aTSA and 0RRK00Z and 0RRJ00Z for RTSA. Procedures were categorized by diagnoses: osteoarthritis (OA), rheumatoid arthritis (RA), avascular necrosis (AVN), fracture, and rotator cuff arthropathy (RCA). Costs were calculated by utilizing the total hospital charge and each hospital's cost-to-charge ratio. Hospital characteristics were included, such as volume of procedures performed by the respective hospital for the calendar year and wage index, which represents the relative average hospital wage for the respective geographic area. Unplanned readmissions within 90 days were calculated using unique patient identifiers, and cost of readmissions was added to the total admission cost to represent the short-term perioperative health care cost. Machine learning algorithms were used to predict patients with immediate postoperative admission costs greater than 1 standard deviation from the mean, and readmissions.Results A total of 49,354 patients were isolated for analysis, with an average patient age of 69.9 ± 9.6 years. The average perioperative cost of care was $18,843 ± $10,165. In total, there were 4279 all-cause readmissions, resulting in an average cost of $13,871.00 ± $14,301.06 per readmission. Wage index, hospital volume, patient age, readmissions, and diagnosis-related group severity were the factors most correlated with the total cost of care. The logistic regression and random forest algorithms were equivalent in predicting the total cost of care (area under the receiver operating characteristic curve = 0.83).Conclusion After shoulder arthroplasty, there is significant variability in cumulative hospital costs, and this is largely affected by readmissions. Hospital characteristics, such as geographic area and volume, are key determinants of overall health care cost. When accounting for this, machine learning algorithms may predict cases with high likelihood of increased resource utilization and/or readmission.
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Deep learning programs that use data from medical records can identify cost of care variations.
“In addition, deep learning programs that use data from medical records can identify cost of care variations [32,33] and provide learning opportunities through customized feedback on individual practices [23].”
From Reimagining Core Entrustable Professional Activities for Undergraduate Medical Education in the Era of Artificial Intelligence (2023) · cites this paper as [32]
Cites
Increasing Incidence of Shoulder Arthroplasty in the United States
Kim, S. H., Wise, B. L., Zhang, Y., et al. (2011) · Journal of Bone and Joint Surgery · doi:10.2106/jbjs.j.01994 · Cited by 980 · see citing works
Prevalence and projections of total shoulder and elbow arthroplasty in the United States to 2015
Day, J. S., Lau, E., Ong, K. L., et al. (2010) · Journal of Shoulder and Elbow Surgery · doi:10.1016/j.jse.2010.02.009 · Cited by 818 · see citing works
Wagner, E. R., Farley, K. X., Higgins, I. A., et al. (2020) · Journal of Shoulder and Elbow Surgery · doi:10.1016/j.jse.2020.03.049 · Cited by 643 · see citing works
Best, M. J., Aziz, K. T., Wilckens, J. H., et al. (2020) · Journal of Shoulder and Elbow Surgery · doi:10.1016/j.jse.2020.08.010 · Cited by 492 · see citing works
Complication rates comparing primary with revision reverse total shoulder arthroplasty
Saltzman, B. M., Chalmers, P. N., Gupta, A. K., Romeo, A. A., & Nicholson, G. P. (2014) · Journal of Shoulder and Elbow Surgery · doi:10.1016/j.jse.2014.04.015 · Cited by 166 · see citing works
Self-citationNavarro, S. M., Wang, E. Y., Haeberle, H. S., Mont, M. A., Krebs, V. E., Patterson, B. M., & Ramkumar, P. N. (2018) · The Journal of Arthroplasty · doi:10.1016/j.arth.2018.08.028 · Cited by 157 · see citing works
Ramkumar, P. N., Navarro, S. M., Haeberle, H. S., Karnuta, J. M., Mont, M. A., Iannotti, J. P., Patterson, B. M., & Krebs, V. E. (2018) · The Journal of Arthroplasty · doi:10.1016/j.arth.2018.12.030 · Cited by 143 · see citing works
Hospital readmissions after primary shoulder arthroplasty
Schairer, W. W., Zhang, A. L., & Feeley, B. T. (2014) · Journal of Shoulder and Elbow Surgery · doi:10.1016/j.jse.2013.12.004 · Cited by 133 · see citing works
Liu, C. Y., Zygourakis, C. C., Yoon, S., et al. (2017) · Spine · doi:10.1097/brs.0000000000001999 · Cited by 133 · see citing works
Gowd, A. K., Agarwalla, A., Amin, N. H., Romeo, A. A., Nicholson, G. P., Verma, N. N., & Liu, J. N. (2019) · Journal of Shoulder and Elbow Surgery · doi:10.1016/j.jse.2019.05.017 · Cited by 91 · see citing works
Self-citationBiron, D. R., Sinha, I., Kleiner, J. E., Aluthge, D. P., Goodman, A. D., Sarkar, I. N., Cohen, E. M., & Daniels, A. H. (2019) · Journal of the American Academy of Orthopaedic Surgeons · doi:10.5435/jaaos-d-19-00395 · Cited by 91 · see citing works
The Association between Hospital Volume and Total Shoulder Arthroplasty Outcomes
Lyman, S. L., Jones, E. C., Bach, P. B., et al. (2005) · Clinical Orthopaedics and Related Research · doi:10.1097/01.blo.0000150571.51381.9a · Cited by 87 · see citing works
Kumar, V., Roche, C. P., Overman, S. S., Simovitch, R. W., Flurin, P.-H., Wright, T. W., Zuckerman, J. D., Routman, H. D., & Teredesai, A. M. (2020) · Journal of Shoulder and Elbow Surgery · doi:10.1016/j.jse.2020.07.042 · Cited by 85 · see citing works
Khlopas, A., Grits, D., Sax, O. C., Chen, Z., Orr, M. N., Klika, A. K., Mont, M. A., & Piuzzi, N. S. (2022) · The Journal of Arthroplasty · doi:10.1016/j.arth.2022.01.032 · Cited by 81 · see citing works
Variation in the Cost of Care for Different Types of Joint Arthroplasty
Carducci, M. P., Gasbarro, G. V., Menendez, M. E., et al. (2019) · Journal of Bone and Joint Surgery · doi:10.2106/jbjs.19.00164 · Cited by 76 · see citing works
Menendez, M. E., Lawler, S. M., Shaker, J. M., Bassoff, N., Warner, J. J. P., & Jawa, A. (2018) · Journal of Bone and Joint Surgery · doi:10.2106/jbjs.18.00281 · Cited by 68 · see citing works
Karnuta, J. M., Churchill, J. L., Haeberle, H. S., Nwachukwu, B. U., Taylor, S. A., Ricchetti, E. T., & Ramkumar, P. N. (2020) · Journal of Shoulder and Elbow Surgery · doi:10.1016/j.jse.2020.04.009 · Cited by 68 · see citing works
Karnuta, J. M., Navarro, S. M., Haeberle, H. S., Billow, D. G., Krebs, V. E., & Ramkumar, P. N. (2019) · Journal of Orthopaedic Trauma · doi:10.1097/bot.0000000000001454 · Cited by 62 · see citing works
Polce, E. M., Kunze, K., Fu, M. C., Garrigues, G., Forsythe, B., Nicholson, G., Cole, B., & Verma, N. (2020) · Journal of shoulder and elbow surgery · doi:10.1016/j.jse.2020.09.007 · Cited by 60 · see citing works
Fang, C. J., Shaker, J. M., Ward, D. M., et al. (2021) · The Journal of Arthroplasty · doi:10.1016/j.arth.2021.03.044 · Cited by 59 · see citing works
The effect of lower socioeconomic status insurance on outcomes after primary shoulder arthroplasty
Waldrop, L. D., King, J. J., Mayfield, J. D., Farmer, K. W., Struk, A. M., Wright, T. W., & Schoch, B. S. (2018) · Journal of Shoulder and Elbow Surgery · doi:10.1016/j.jse.2018.01.002 · Cited by 57 · see citing works
Recent trends in Medicare utilization and surgeon reimbursement for shoulder arthroplasty
Lopez, C. D., Boddapati, V., Anderson, M. J. J., et al. (2020) · Journal of Shoulder and Elbow Surgery · doi:10.1016/j.jse.2020.04.030 · Cited by 48 · see citing works
Haas, D. A., Bozic, K. J., DiGioia, A. M., Song, Z., & Kaplan, R. S. (2016) · The Journal of Arthroplasty · doi:10.1016/j.arth.2016.07.030 · Cited by 46 · see citing works
Arvind, V., London, D. A., Cirino, C. M., et al. (2020) · Journal of Shoulder and Elbow Surgery · doi:10.1016/j.jse.2020.05.013 · Cited by 44 · see citing works
Defining the Volume-Outcome Relationship in Reverse Shoulder Arthroplasty
Farley, K. X., Schwartz, A., Boden, S. H., et al. (2020) · Journal of Bone and Joint Surgery · doi:10.2106/jbjs.19.01012 · Cited by 41 · see citing works
Machine Learning Can Predict Level of Improvement in Shoulder Arthroplasty
McLendon, P. B., Christmas, K. N., Simon, P., Plummer, O. R., Hunt, A., Ahmed, A. S., Mighell, M. A., & Frankle, M. A. (2021) · JBJS Open Access · doi:10.2106/jbjs.oa.20.00128 · Cited by 39 · see citing works
Outpatient Total Shoulder Arthroplasty
Vajapey, S. P., Contreras, E. S., Neviaser, A. S., et al. (2021) · JBJS Reviews · doi:10.2106/jbjs.rvw.20.00189 · Cited by 35 · see citing works
Carducci, M. P., Mahendraraj, K. A., Menendez, M. E., et al. (2020) · Journal of Shoulder and Elbow Surgery · doi:10.1016/j.jse.2020.04.033 · Cited by 30 · see citing works
Analysis of 90-Day Readmissions After Total Shoulder Arthroplasty
Chung, A. S., Makovicka, J. L., Hydrick, T. C., et al. (2019) · Orthopaedic Journal of Sports Medicine · doi:10.1177/2325967119868964 · Cited by 25 · see citing works
Kamath, C. C., O'Byrne, T. J., Lewallen, D. G., Berry, D. J., & Kremers, H. M. (2022) · The Journal of Arthroplasty · doi:10.1016/j.arth.2022.03.063 · Cited by 24 · see citing works
Polveroni, T. M., Haglin, J. M., McQuivey, K. S., et al. (2022) · Journal of Shoulder and Elbow Surgery · doi:10.1016/j.jse.2022.02.034 · Cited by 24 · see citing works
The effect of an orthopedic specialty hospital on operating room efficiency in shoulder arthroplasty
Padegimas, E. M., Hendy, B. A., Chan, W. W., et al. (2018) · Journal of Shoulder and Elbow Surgery · doi:10.1016/j.jse.2018.06.035 · Cited by 15 · see citing works
DRG-based bundled reimbursement for lumbar fusion: implications for patient selection
Yee, P., Tanenbaum, J. E., Pelle, D. W., Moore, D., Benzel, E. C., Steinmetz, M. P., & Mroz, T. E. (2019) · Journal of Neurosurgery Spine · doi:10.3171/2019.3.spine18875 · Cited by 14 · see citing works
Malik, A. T., Sridharan, M. J., Bishop, J. Y., et al. (2020) · Journal of Shoulder and Elbow Surgery · doi:10.1016/j.jse.2019.12.029 · Cited by 14 · see citing works
Chawla, S. S., Whitson, A. J., Schiffman, C. J., et al. (2020) · Journal of Shoulder and Elbow Surgery · doi:10.1016/j.jse.2020.10.030 · Cited by 11 · see citing works
Koressel, J. E., Perez, B. A., DeAngelis, R. D., et al. (2022) · The Journal of Arthroplasty · doi:10.1016/j.arth.2022.03.018 · Cited by 10 · see citing works
Understanding the Value of Total Shoulder Arthroplasties at Physician-Owned Hospitals
Malik, A. T., Sridharan, M. J., Bishop, J. Y., et al. (2020) · Journal of the American Academy of Orthopaedic Surgeons · doi:10.5435/jaaos-d-19-00750 · Cited by 3 · see citing works
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Jacobs, S. M., Lundy, N. N., Issenberg, S. B., & Chandran, L. (2023) · JMIR Medical Education · doi:10.2196/50903 · Cited by 33 · see citing works
- Authors
- Gowd, A. K., Agarwalla, A., Beck, E. C., Rosas, S., Waterman, B. R., Romeo, A. A., & Liu, J. N.
- Affiliations
- Atrium Health Wake Forest Baptist (US)
- Westchester Medical Center (US)
- University of Southern California (US)
- Corresponding author
- Liu, Joseph N.
- ORCID
- Venue
- Journal of Shoulder and Elbow Surgery
- Publisher
- Elsevier BV
- Published
- 2022-12
- Volume
- 31
- Issue
- 12
- Pages
- 2449-2456
- ISSN
- 1058-2746 (ISSN-L)
- OpenAlex
- W4292622580
- Cited by
- 45
- References
- 37
- Citations by year
- 2026: 10 · 2025: 11 · 2024: 17 · 2023: 6
- FWCI
- 8.12
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Shoulder and Elbow Surgery (publishedVersion)
- PubMed (publishedVersion)
- Funders
- American Shoulder and Elbow Surgeons
- Topics
- Health Sciences › Medicine › Surgery › Shoulder Injury and Treatment
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Healthcare Policy and Management
- Health Sciences › Medicine › Surgery › Total Knee Arthroplasty Outcomes
- Keywords
- total shoulder arthroplasty, reverse shoulder arthroplasty, healthcare cost prediction, hospital readmission, glenohumeral arthritis, bundled payment, hospital volume, wage index, random forest, logistic regression, osteoarthritis, rheumatoid arthritis, avascular necrosis, rotator cuff arthropathy
- MeSH terms
- Machine Learning, Arthroplasty, Replacement, Shoulder, Aged, Humans, Middle Aged, Osteoarthritis, Retrospective Studies, Shoulder Joint, Treatment Outcome, Rotator Cuff, Health Care Costs
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