The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Endocrinologic Control of Men’s Sexual Desire and Arousal/Erection
Open accessAbstract
Introduction: Several hormones and neurotransmitters orchestrate men’s sexual response, including the appetitive (sexual desire) and consummative (arousal and penile erection) phases. Aim: To provide an overview and recommendations regarding endocrinologic control of sexual desire and arousal and erection and their disturbances. Methods: Medical literature was reviewed by the subcommittee of the International Consultation of Sexual Medicine, followed by extensive internal discussion, and then public presentation and discussion with other experts. The role of pituitary (prolactin, oxytocin, growth hormone, and α-melanocyte-stimulating hormone), thyroid, and testicular hormones was scrutinized and discussed. Main Outcome Measures: Recommendations were based on grading of evidence-based medical literature, followed by interactive discussion. Results: Testosterone has a primary role in controlling and synchronizing male sexual desire and arousal, acting at multiple levels. Accordingly, meta-analysis indicates that testosterone therapy for hypogonadal individuals can improve low desire and erectile dysfunction. Hyperprolactinemia is associated with low desire that can be successfully corrected by appropriate treatments. Oxytocin and α-melanocyte-stimulating hormone are important in eliciting sexual arousal; however, use of these peptides, or their analogs, for stimulating sexual arousal is still under investigation. Evaluation and treatment of other endocrine disorders are suggested only in selected cases. Conclusion: Endocrine abnormalities are common in patients with sexual dysfunction. Their identification and treatment is strongly encouraged in disturbances of sexual desire and arousal.
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Cites
Impotence and Its Medical and Psychosocial Correlates: Results of the Massachusetts Male Aging Study
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Gonadal Steroids and Body Composition, Strength, and Sexual Function in Men
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The endocrinology of sexual arousal
Bancroft, J. (2005) · Journal of Endocrinology · doi:10.1677/joe.1.06233 · Cited by 398 · cited 5×
“However, a direct effect of increased PRL on sexual desire also was hypothesized.(1,42) In fact, PRL receptors were found in the diencephalic incertohypothalamic dopaminergic system, a pathway of short axons with terminals in the medial preoptic area, the most important area for the control of motivational and consumm…”
BackgroundResultInfluentialOxytocin enhances brain reward system responses in men viewing the face of their female partner
Scheele, D., Wille, A., Kendrick, K. M., Stoffel-Wagner, B., Becker, B., Güntürkün, O., Maier, W., & Hurlemann, R. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1314190110 · Cited by 340 · cited 2×
“In a double-blinded, placebo-controlled RCT, a specific effect of intranasal OTwas found in perceiving the partner as attractive, with magnetic resonance imagingederived activation of brain regions involved in reward, such as the ventral tegmental area and the nucleus accumbens, but without a specific effect on arousa…”
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Cited by
Corona, G., Goulis, D. G., Huhtaniemi, I., Zitzmann, M., Toppari, J., Forti, G., Vanderschueren, D., & Wu, F. C. (2020) · Andrology · doi:10.1111/andr.12770 · Cited by 431
Self-citation
Metadata
- Authors
- Corona, G., Isidori, A. M., Aversa, A., Burnett, A. L., & Maggi, M.
- Venue
- The Journal of Sexual Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2016-03-01
- Volume
- 13
- Issue
- 3
- Pages
- 317-337
- ISSN
- 1743-6095 (ISSN-L)
- 1743-6109
- OpenAlex
- W2292315528
- Cited by
- 172
- References
- 22
- FWCI
- 18.37
- Type
- journal article
- Language
- en
- Open access
- green
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