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Cited by 155Protist diversity and phylogenyOrigins and Evolution of LifeEvolution and Genetic Dynamics

The DOI matches its Crossref record; 206 of the 206 references it cites were found in a registry or an index.

Symbiosis in eukaryotic evolution

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López-García, Purificación, Eme, Laura, Moreira, David·2017·Journal of Theoretical Biology
DOI 10.1016/j.jtbi.2017.02.031PMC PMC5638015
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Abstract

Fifty years ago, Lynn Margulis, inspiring in early twentieth-century ideas that put forward a symbiotic origin for some eukaryotic organelles, proposed a unified theory for the origin of the eukaryotic cell based on symbiosis as evolutionary mechanism. Margulis was profoundly aware of the importance of symbiosis in the natural microbial world and anticipated the evolutionary significance that integrated cooperative interactions might have as mechanism to increase cellular complexity. Today, we have started fully appreciating the vast extent of microbial diversity and the importance of syntrophic metabolic cooperation in natural ecosystems, especially in sediments and microbial mats. Also, not only the symbiogenetic origin of mitochondria and chloroplasts has been clearly demonstrated, but improvement in phylogenomic methods combined with recent discoveries of archaeal lineages more closely related to eukaryotes further support the symbiogenetic origin of the eukaryotic cell. Margulis left us in legacy the idea of 'eukaryogenesis by symbiogenesis'. Although this has been largely verified, when, where, and specifically how eukaryotic cells evolved are yet unclear. Here, we shortly review current knowledge about symbiotic interactions in the microbial world and their evolutionary impact, the status of eukaryogenetic models and the current challenges and perspectives ahead to reconstruct the evolutionary path to eukaryotes.

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  1. Cavalier-Smith, 1989, Molecular phylogeny, Archaebacteria Archezoa. Nat., 339, l00
  2. Mereschkowsky, 1905, Über natur und usprung der chromatophoren im pflanzenreiche, Biol. Cent., 25, 593
  3. Yan, 1993, Significance of eukaryotic organisms in the microfossil flora of Changcheng system, Acta Micropalaeontol Sin., 10, 167

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Metadata

Authors
López-García, P., Eme, L., & Moreira, D.
Affiliations
  • Dalhousie University (CA)
  • Université Paris-Sud (FR)
ORCID
Venue
Journal of Theoretical Biology
Publisher
Elsevier BV
Published
2017-12
Volume
434
Pages
20-33
ISSN
0022-5193 (ISSN-L)
DOI
10.1016/j.jtbi.2017.02.031
PMC
PMC5638015
OpenAlex
W2592590328
Cited by
154
References
206
Citations by year
2026: 8 · 2025: 14 · 2024: 12 · 2023: 14 · 2022: 15 · 2021: 18 · 2020: 24 · 2019: 24 · 2018: 13 · 2017: 12
FWCI
8.16
Type
journal article
Language
en
Open access
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Journal of Theoretical Biology (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
European Research Council Advanced (322669)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Protist diversity and phylogeny
  • Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
Keywords
symbiosis, eukaryotic origin, symbiogenesis, Lynn Margulis, endosymbiotic origin of mitochondria, chloroplast origin, eukaryotic organelles, microbial mats, sediment microbial communities, archaea, phylogenomics, eukaryotic evolution
MeSH terms
Eukaryotic Cells, Biological Evolution, Symbiosis, Ecosystem, Eukaryota, Microbiota

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