Cited by 29Atrial Fibrillation Management and OutcomesCardiac Arrhythmias and TreatmentsCardiac pacing and defibrillation studies

Thoracoscopic pulmonary vein isolation in patients with atrial fibrillation and failed percutaneous ablation

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Castellá, Manuel, Pereda, Daniel, Mestres, Carlos A., Gómez, Félix, Quintana, Eduard, Mulet, Jaume·2010·The Journal of Thoracic and Cardiovascular Surgery

Abstract

Objective Pulmonary vein isolation is indicated in patients with symptomatic isolated atrial fibrillation not controlled with antiarrhythmic therapy. We describe our surgical experience with thoracoscopic pulmonary vein isolation in patients in whom percutaneous ablation has failed.Methods Thirty-four adult patients with unsuccessful catheter ablations (range 1-4, mean 2 +/- 1) underwent thoracoscopic bipolar-radiofrequency pulmonary vein isolation. Seventeen patients had paroxysmal atrial fibrillation, 12 with persistent and 5 with long-standing persistent fibrillation, for a mean of 6 years (range 3-10 years), 13 years (5-25 years), and 9 years (3-15 years), respectively.Results There was no mortality during the procedure or follow-up (mean 16 +/- 11 months). Two patients needed conversion to thoracotomy owing to hemorrhage, and ablation could not be completed. Antiarrhythmic therapy was withdrawn 3 months postoperatively. Postoperative sinus rhythm was maintained in 82% of those with paroxysmal atrial fibrillation (13/15 at 6 months, 9/11 at 12 months), 60% had persistent atrial fibrillation (8/12 at 6 months and 6/10 at 12 months), and 20% had long-standing persistent atrial fibrillation (1/5 at 6 and 12 months). Preoperative left atrial diameter significantly differed between patients with paroxysmal fibrillation (mean 42 +/- 6 mm) and those with persistent and long-standing persistent fibrillation (means 50 +/- 4 and 47 +/- 2 mm). Left atrial size greater than 45 mm and atrial fibrillation type were preoperative factors that significantly influenced outcome in the univariate logistic regression analysis.Conclusions Thoracoscopic pulmonary vein isolation in patients with previously unsuccessful catheter ablations demonstrates satisfactory sinus rhythm maintenance rates in paroxysmal and persistent atrial fibrillation, but not in long-standing persistent atrial fibrillation. As with other minimally invasive surgical techniques, there is an important learning curve.

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  1. Fuster V, Ryden LE, Cannom DS, Crijns HJ, Curtis AB, Ellenbogen KA, et al. [ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fi- brillation-excutive summary] [in Portuguese]. Rev Port Cardiol. 2007;26: 383-446.

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Authors
Castellá, M., Pereda, D., Mestres, C. A., Gómez, F., Quintana, E., & Mulet, J.
Affiliations
Hospital Clínic de Barcelona (ES)
Venue
The Journal of Thoracic and Cardiovascular Surgery
Publisher
Elsevier BV
Published
2010-09
Volume
140
Issue
3
Pages
633-638
ISSN
0022-5223 (ISSN-L)
OpenAlex
W2001564316
Cited by
29
References
13
Citations by year
2026: 1 · 2024: 1 · 2022: 2 · 2021: 2 · 2020: 1 · 2018: 1 · 2016: 5 · 2015: 6 · 2012: 4
FWCI
1.98
Type
journal article
Language
en
Open access
Locations
  • Journal of Thoracic and Cardiovascular Surgery (publishedVersion)
  • PubMed (publishedVersion)
Funders
AtriCure
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
Keywords
atrial fibrillation, failed catheter ablation, radiofrequency ablation, bipolar radiofrequency, paroxysmal atrial fibrillation, persistent atrial fibrillation, long-standing persistent atrial fibrillation, sinus rhythm maintenance, left atrial size, minimally invasive cardiac surgery
MeSH terms
Adult, Aged, Atrial Fibrillation, Female, Humans, Male, Middle Aged, Pulmonary Veins, Risk Factors, Spain, Thoracotomy, Time Factors, Logistic Models, Catheter Ablation, Treatment Failure, Risk Assessment, Thoracic Surgery, Video-Assisted

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