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Cited by 180Mechanical Circulatory Support DevicesCongenital Heart Disease StudiesCardiac and Coronary Surgery Techniques

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Extracorporeal membrane oxygenation in postcardiotomy patients: Factors influencing outcome

Open access
Kumar, T.K. Susheel, Zurakowski, David, Dalton, Heidi, Talwar, Sachin, Allard-Picou, Ayana, Duebener, Lennart F., Sinha, Pranava, Moulick, Achintya·2010·The Journal of Thoracic and Cardiovascular Surgery
DOI 10.1016/j.jtcvs.2010.02.034
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Abstract

Objective Our objective was to assess the morbidity and mortality in children requiring extracorporeal membrane oxygenator support after cardiac surgery and to determine factors influencing outcome. Methods Between January 2003 and June 2008, 58 patients required extracorporeal membrane oxygenator support after cardiac surgery. A retrospective study was performed and factors influencing outcome were determined by logistic regression modeling with the probability of outcome based on a combination of multivariate predictors. Results Median age and weight were 12 days and 3.3 kg, respectively. Thirty-one patients had single ventricle repair and 27 had biventricular repair. Median duration of support with the oxygenator was 6 days. Thirty-nine (67%) patients were successfully weaned off the support, but only 24 (41%) survived to hospital discharge. Chief complications were renal failure (31%), neurologic complications (29%), and sepsis (16%). Multivariable logistic regression analysis identified 10 days or more of extracorporeal membrane oxygenation (odds ratio = 6.1), urine output less than 2 mL x kg(-1) x h(-1) in first 24 hours (odds ratio = 15), renal failure (odds ratio = 9.4), and pH less than 7.35 after 24 hours of extracorporeal membrane oxygenation (odds ratio = 82) as significant independent factors associated with failure to wean off extracorporeal membrane oxygenation. Factors associated with failure of hospital discharge despite successful decannulation were as follows: extracorporeal membrane oxygenator support time of 10 days or more, red blood cell transfusion of greater than 1000 mL/kg during the entire period of oxygenator support, and sepsis. Patients with single ventricle repair were at higher risk of hospital mortality. Conclusion Longer duration of extracorporeal membrane oxygenator support, low pH and urine output in the first 24 hours, and renal failure are significant factors associated with mortality during extracorporeal membrane oxygenator support. Exposure to high amounts of blood transfusion during extracorporeal oxygenation, extended extracorporeal membrane oxygenator support, and sepsis increase risk of death after successful decannulation.

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Crossref · 10.1016/j.jtcvs.2010.02.034

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1 of 1 references verified0 citation errors · 0 not checkable

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Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Progressive low cardiac output syndrome is the cause for 36% of post-operative extracorporeal life support cannulations, making it one of the most common indications for extracorporeal life support in the post-operative period.

    “Progressive LCOS is the cause for 36% of post-operative ECLS cannulations, making it one of the most common indications for ECLS in the post-operative period [28-32].”

    From Management of the Low Cardiac Output Syndrome Following Surgery for Congenital Heart Disease (2016) · cites this paper as [30]

  • Survival of pediatric patients who receive extracorporeal life support after cardiac surgery is approximately 41-49%.

    “Survival of pediatric patients who receive ECLS after cardiac surgery is approximately 41-49% [28-32].”

    From Management of the Low Cardiac Output Syndrome Following Surgery for Congenital Heart Disease (2016) · cites this paper as [30]

Citations

Cites

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Research works printed but not linked: 22

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Metadata

Authors
Kumar, T. K. S., Zurakowski, D., Dalton, H., Talwar, S., Allard-Picou, A., Duebener, L. F., Sinha, P., & Moulick, A.
Affiliations
Children's National (US)
Corresponding author
Moulick, Achintya
ORCID
Venue
The Journal of Thoracic and Cardiovascular Surgery
Publisher
Elsevier BV
Published
2010-08
Volume
140
Issue
2
Pages
330-336.e2
ISSN
0022-5223 (ISSN-L)
DOI
10.1016/j.jtcvs.2010.02.034
OpenAlex
W2071922723
Cited by
180
References
1
Citations by year
2026: 3 · 2025: 2 · 2024: 7 · 2023: 10 · 2022: 12 · 2021: 11 · 2020: 14 · 2019: 14 · 2018: 12 · 2017: 18 · 2016: 16 · 2015: 14 · 2014: 18 · 2013: 10 · 2012: 9
FWCI
5.01
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Thoracic and Cardiovascular Surgery (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Mechanical Circulatory Support Devices
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Congenital Heart Disease Studies
  • Health Sciences › Medicine › Surgery › Cardiac and Coronary Surgery Techniques
Keywords
extracorporeal membrane oxygenation, pediatric cardiac surgery, single ventricle repair, biventricular repair, renal failure, sepsis, acidosis, urine output, red blood cell transfusion, ECMO weaning, mortality, decannulation
MeSH terms
Blood Transfusion, Female, Heart Defects, Congenital, Cardiac Surgical Procedures, Humans, Hydrogen-Ion Concentration, Infant, Infant, Newborn, Male, Patient Discharge, Postoperative Care, Retrospective Studies, Risk Factors, Time Factors, Urination, Extracorporeal Membrane Oxygenation, Logistic Models, Odds Ratio, Treatment Outcome, Hospital Mortality, Risk Assessment, Sepsis, Renal Insufficiency, Kaplan-Meier Estimate

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