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Cited by 600

The DOI matches its Crossref record; 129 of the 129 references it cites were found in a registry or an index.

The International Epidemiology of Lung Cancer: Latest Trends, Disparities, and Tumor Characteristics

Open access
Cheng, Ting-Yuan David, Cramb, Susanna M., Baade, Peter D., Youlden, Danny R., Nwogu, Chukwumere, Reid, Mary E.·2016·Journal of Thoracic Oncology

Abstract

Introduction: Our aim was to update global lung cancer epidemiology and describe changing trends and disparities. Methods: We presented country‐specific incidence and mortality from GLOBOCAN 2012 by region and socioeconomic factors via the Human Development Index (HDI). Between‐ and within‐country incidence by histological type was analyzed by using International Agency for Research on Cancer data on cancer incidence on five continents. Trend analyses including data from the International Agency for Research on Cancer, cancer registries, and the WHO mortality database were conducted using joinpoint regression. Survival was compared between and within countries and by histological type. Results: In 2012, there were 1.82 and 1.59 million new lung cancer cases and deaths worldwide, respectively. Incidence was highest in countries with a very high HDI and lowest in countries with a low HDI (42.2 versus 7.9 in 100,000 for males and 21.8 versus 3.1 in 100,000 for females, respectively). In most countries with a very high HDI, as incidence in males decreased gradually (ranging from –0.3% in Spain to –2.5% in the United States each year), incidence in females continued to increase (with the increase ranging from 1.4% each year in Australia to 6.1% in recent years in Spain). Although histological type varied between countries, adenocarcinoma was more common than squamous cell carcinoma, particularly among females (e.g., in Chinese females, the adenocarcinoma‐to–squamous cell carcinoma ratio was 6.6). Five‐year relative survival varied from 2% (Libya) to 30% (Japan), with substantial within‐country differences. Conclusions: Lung cancer will continue to be a major health problem well through the first half of this century. Preventive strategies, particularly tobacco control, tailored to populations at highest risk are key to reducing the global burden of lung cancer.

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Metadata

Authors
Cheng, T.-Y. D., Cramb, S. M., Baade, P. D., Youlden, D. R., Nwogu, C., & Reid, M. E.
Venue
Journal of Thoracic Oncology
Publisher
Elsevier BV
Published
2016-10
Volume
11
Issue
10
Pages
1653-1671
ISSN
1556-0864 (ISSN-L)
OpenAlex
W2472596403
Cited by
600
References
129
FWCI
27.35
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The International Epidemiology of Lung Cancer: Latest Trends, Disparities, and Tumor Characteristics. https://app.cochat.ai/papers/10.1016/j.jtho.2016.05.021
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Cheng, T.-Y. D., Cramb, S. M., Baade, P. D., Youlden, D. R., Nwogu, C., & Reid, M. E. (2016). The International Epidemiology of Lung Cancer: Latest Trends, Disparities, and Tumor Characteristics. Journal of Thoracic Oncology. https://doi.org/10.1016/j.jtho.2016.05.021

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