CoChat
Sign Up
Cited by 86

The DOI matches its Crossref record.

Evidence-based recommendations for the use of negative pressure wound therapy in chronic wounds: Steps towards an international consensus

Vig, S., Dowsett, C., Berg, L., Caravaggi, C., Rome, P., Birke-Sorensen, H., Bruhin, A., Chariker, M., Depoorter, M., Dunn, R., Duteille, F., Ferreira, F., Francos Martínez, J.M., Grudzien, G., Hudson, D., Ichioka, S., Ingemansson, R., Jeffery, S., Krug, E., Lee, C., Malmsjo, M., Runkel, N., Martin, R., Smith, J.·2011·Journal of Tissue Viability
DOI 10.1016/j.jtv.2011.07.002
Open this paper in CoChat — free account

Abstract

Aim Negative Pressure Wound Therapy (NPWT) has become widely adopted over the last 15 years and over 1000 peer-reviewed publications are available describing its use. Despite this, there remains uncertainty regarding several aspects of usage. In order to respond to this gap a global expert panel was convened to develop evidence-based recommendations describing the use of NPWT. In this communication the results of the study of evidence in chronic wounds including pressure ulcers, diabetic foot ulcers (DFU), venous leg ulcers (VLU), and ischaemic lower limb wounds are reported. Methods Evidence-based recommendations were obtained by a systematic review of the literature, grading of evidence, drafting of the recommendations by a global expert panel followed by a formal consultative consensus development program in which 422 independent healthcare professionals were able to agree or disagree with the recommendations. The criteria for agreement were set at 80% agreement. Evidence and recommendations were graded according to the SIGN (Scottish Intercollegiate Guidelines Network) classification system. Results The primary treatment goal of NPWT in most chronic wounds is to achieve wound closure (either by secondary intention or preparing the wound for surgical closure). Secondary goals commonly include: to reduce wound dimensions, and to improve the quality of the wound bed. Thirteen evidence based recommendations were developed in total to address these treatment goals; 4 for press…

Overview

Integrity signals

Registry

Crossref · 10.1016/j.jtv.2011.07.002

Cites

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

No references could be resolved yet.

Research works printed but not linked: 84

  1. Krug, 2011, Evidence-based recommendations for the use of Negative Pressure Wound Therapy in traumatic wounds and reconstructive surgery: steps towards an international consensus, Injury, 42, S1, 10.1016/S0020-1383(11)00041-6 · DOI
  2. Laney, 2009, Topical negative pressure wound therapy (TNPWT): current practice in New Zealand, N Z Med J, 122, 19
  3. Mendonca, 2007, A pilot study on the effect of topical negative pressure on quality of life, J Wound Care, 16, 49, 10.12968/jowc.2007.16.2.27008 · DOI
  4. Gupta, 2004, Guidelines for managing pressure ulcers with negative pressure wound therapy, Adv Skin Wound Care, 17, 1, 10.1097/00129334-200411002-00001 · DOI
  5. Niezgoda, 2006, The effective management of pressure ulcers, Adv Skin Wound Care, 19, 3, 10.1097/00129334-200601001-00001 · DOI
  6. Nakayama, 2010, Applying negative pressure therapy to deep pressure ulcers covered by soft necrotic tissue, Int Wound J, 7, 160, 10.1111/j.1742-481X.2010.00667.x · DOI
  7. Wanner, 2003, Vacuum-assisted wound closure for cheaper and more comfortable healing of pressure sores: a prospective study, Scand J Plast Reconstr Surg Hand Surg, 37, 28, 10.1080/713796078 · DOI
  8. Ford, 2002, Interim analysis of a prospective, randomized trial of vacuum-assisted closure versus the healthpoint system in the management of pressure ulcers, Ann Plast Surg, 49, 55, 10.1097/00000637-200207000-00009 · DOI
  9. Coggrave, 2002, Topical negative pressure for pressure ulcer management.68, Br J Nurs, 11, S29, 10.12968/bjon.2002.11.Sup1.12247 · DOI
  10. Ferreira, 2003, The vacuum assisted closure of complex wounds: report of 3 cases, Rev Hosp Clin Fac Med Sao Paulo, 58, 227, 10.1590/S0041-87812003000400008 · DOI
  11. Maguina, 2008, Posterior rectal hernia after vacuum-assisted closure treatment of sacral pressure ulcer, Plast Reconstr Surg, 122, 46e, 10.1097/PRS.0b013e3181774682 · DOI
  12. Mody, 2008, A blinded, prospective, randomized controlled trial of topical negative pressure wound closure in India, Ostomy Wound Manage, 54, 36
  13. Baharestani, 2008, Early versus late initiation of negative pressure wound therapy: examining the impact on home care length of stay, Ostomy Wound Manage, 54, 48
  14. Chaouat, 2006, Topical negative pressure for the treatment of complex cavity wounds associated with osteitis, J Wound Care, 15, 292, 10.12968/jowc.2006.15.7.26933 · DOI
  15. Gabriel, 2009, A Clinical review of infected wound treatment with Vacuum Assisted Closure® (V.A.C.®) therapy: experience and case series, Int Wound J, 6, 1, 10.1111/j.1742-481X.2009.00628.x · DOI
  16. Müllner, 1997, The use of negative pressure to promote the healing of tissue defects: a clinical trial using the vacuum sealing technique, Br J Plast Surg, 50, 194, 10.1016/S0007-1226(97)91369-2 · DOI
  17. Tachi, 2004, Topical negative pressure using a drainage pouch without foam dressing for the treatment of undermined pressure ulcers, Ann Plast Surg, 53, 338, 10.1097/01.sap.0000129234.84192.d4 · DOI
  18. Joseph, 2000, A prospective, randomized trial of vacuum-assisted closure versus standard therapy of chronic non-healing wounds, Wounds, 12, 60
  19. Philbeck, 1999, The clinical and cost effectiveness of externally applied negative pressure wound therapy in the treatment of wounds in home healthcare Medicare patients, Ostomy Wound Manage, 45, 41
  20. Deva, 2000, Topical negative pressure in wound management, Med J Aust, 173, 128, 10.5694/j.1326-5377.2000.tb125564.x · DOI
  21. Isago, 2003, Effects of different negative pressures on reduction of wounds in negative pressure dressings, J Dermatol, 30, 596, 10.1111/j.1346-8138.2003.tb00441.x · DOI
  22. Wild, 2008, Definition of efficiency in vacuum therapy – a randomised controlled trial comparing with V.A.C. Therapy, Int Wound J, 5, 641, 10.1111/j.1742-481X.2007.00407.x · DOI
  23. Witkowski, 2009, Initial multi-centre observations upon the effect of a new Topical Negative Pressure device upon patient and clinician experience and the treatment of wounds, Int Wound J, 6, 167, 10.1111/j.1742-481X.2009.00586.x · DOI
  24. Caravaggi, 2009, Gauze-based negative pressure wound therapy (V1STA Smith& Nephew) in the treatment of infected diabetic foot ulcer, Eur Metab Rev
  25. Chadwick, 2009, A dynamic care pathway to coordinate the use of advanced therapy in diabetic foot ulceration, J Wound Care, 18, 433, 10.12968/jowc.2009.18.10.44606 · DOI
  26. Lavery, 2008, Prediction of healing for postoperative diabetic foot wounds based on early wound area progression, Diabetes Care, 31, 26, 10.2337/dc07-1300 · DOI
  27. Oyibo, 2001, A comparison of two diabetic foot ulcer classification systems: the Wagner and the University of Texas wound classification systems, Diabetes Care, 24, 84, 10.2337/diacare.24.1.84 · DOI · Paper page
  28. Armstrong, 2005, Negative pressure wound therapy after partial diabetic foot amputation: a multicentre, randomized controlled trial, Lancet, 366, 1704, 10.1016/S0140-6736(05)67695-7 · DOI · Paper page
  29. Blume, 2008, Comparison of negative pressure wound therapy using vacuum-assisted closure with advanced moist wound therapy in the treatment of diabetic foot ulcers: a multicenter randomized controlled trial, Diabetes Care, 31, 631, 10.2337/dc07-2196 · DOI
  30. McCallon, 2000, Vacuum-assisted closure versus saline-moistened gauze in the healing of postoperative diabetic foot wounds, Ostomy Wound Manage, 46, 28
  31. Flack, 2008, An economic evaluation of VAC therapy compared with wound dressings in the treatment of diabetic foot ulcers, J Wound Care, 17, 71, 10.12968/jowc.2008.17.2.28181 · DOI
  32. Whitehead, 2011, Economic evaluation of Vacuum Assisted Closure® Therapy for the treatment of diabetic foot ulcers in France, Int Wound J, 8, 22, 10.1111/j.1742-481X.2010.00739.x · DOI
  33. Apelqvist, 2008, Resource utilization and economic costs of care based on a randomized trial of vacuum-assisted closure therapy in the treatment of diabetic foot wounds, Am J Surg, 195, 782, 10.1016/j.amjsurg.2007.06.023 · DOI
  34. Lavery, 2007, A comparison of diabetic foot ulcer outcomes using negative pressure wound therapy versus historical standard of care, Int Wound J, 4, 103, 10.1111/j.1742-481X.2007.00317.x · DOI
  35. Dougherty, 2008, An evidence-based model comparing the cost-effectiveness of platelet-rich plasma gel to alternative therapies for patients with nonhealing diabetic foot ulcers, Adv Skin Wound Care, 21, 568, 10.1097/01.ASW.0000323589.27605.71 · DOI
  36. Sepúlveda, 2009, Negative-pressure wound therapy versus standard wound dressing in the treatment of diabetic foot amputation. A randomised controlled trial, Cir Esp, 86, 171, 10.1016/j.ciresp.2009.03.020 · DOI
  37. Frykberg, 2007, Negative-pressure wound therapy and diabetic foot amputations: a retrospective study of payer claims data, J Am Podiatr Med Assoc, 97, 351, 10.7547/0970351 · DOI
  38. Eginton, 2003, A prospective randomized evaluation of negative-pressure wound dressings for diabetic foot wounds, Ann Vasc Surg, 17, 645, 10.1007/s10016-003-0065-3 · DOI
  39. Fife, 2008, The safety of negative pressure wound therapy using vacuum-assisted closure in diabetic foot ulcers treated in the outpatient setting, Int Wound J, 5, 17, 10.1111/j.1742-481X.2008.00467.x · DOI
  40. Armstrong, 2007, Negative pressure wound therapy via vacuum-assisted closure following partial foot amputation: what is the role of wound chronicity?, Int Wound J, 4, 79, 10.1111/j.1742-481X.2006.00270.x · DOI
  41. Clare, 2002, Experience with the vacuum assisted closure negative pressure technique in the treatment of non-healing diabetic and dysvascular wounds, Foot Ankle Int, 23, 896, 10.1177/107110070202301002 · DOI
  42. Ferreira, 2009, Negative pressure therapy (vacuum) for wound bed preparation among diabetic patients: case series, Sao Paulo Med J, 127, 166, 10.1590/S1516-31802009000300010 · DOI
  43. Kopp, 2004, Buried chip skin grafting in neuropathic diabetic foot ulcers following vacuum-assisted wound bed preparation: enhancing a classic surgical tool with novel technologies, Int J Low Extrem Wounds, 3, 168, 10.1177/1534734604268092 · DOI
  44. Lang, 2006, Distal extremity reconstruction for limb salvage in diabetic foot ulcers with pedal bypass, flap plasty and vacuum therapy, Zentralbl Chir, 131, S146, 10.1055/s-2006-921472 · DOI
  45. Nather, 2010, Effectiveness of vacuum-assisted closure (VAC) therapy in the healing of chronic diabetic foot ulcers, Ann Acad Med Singapore, 39, 353, 10.47102/annals-acadmedsg.V39N5p353 · DOI
  46. Tan, 2007, Treatment of long-standing, poor-healing diabetic foot ulcers with topical negative pressure in the Torres Strait, Aust J Rural Health, 15, 275, 10.1111/j.1440-1584.2007.00908.x · DOI
  47. Sandnes, 2004, Survival after lower extremity amputation, J Am Coll Surg, 199, 394, 10.1016/j.jamcollsurg.2004.05.270 · DOI
  48. Mayfield, 2001, Survival following lower-limb amputation in a veteran population, J Rehabil Res Dev, 38, 341
  49. Tentolouris, 2004, Mortality in diabetic and nondiabetic patients after amputations performed from 1990 to 1995: a 5-year follow-up study, Diabetes Care, 27, 1598, 10.2337/diacare.27.7.1598 · DOI
  50. Faglia, 2001, New ulceration, new major amputation, and survival rates in diabetic subjects hospitalized for foot ulceration from 1990 to 1993: a 6.5-year follow-up, Diabetes Care, 24, 78, 10.2337/diacare.24.1.78 · DOI
  51. Peters, 2001, Functional status of persons with diabetes-related lower-extremity amputations, Diabetes Care, 24, 1799, 10.2337/diacare.24.10.1799 · DOI
  52. Coffey, 2002, Valuing health related quality of life in diabetes, Diabetes Care, 25, 2238, 10.2337/diacare.25.12.2238 · DOI
  53. Ollendorf, 1998, Potential economic benefits of lower-extremity amputation prevention strategies in diabetes, Diabetes Care, 21, 1240, 10.2337/diacare.21.8.1240 · DOI
  54. Dzieciuchowicz, 2009, [Vacuum assisted closure (VAC) in the treatment of advanced diabetic foot], Cir Esp, 86, 213, 10.1016/j.ciresp.2009.06.003 · DOI
  55. Gesslein, 2006, Interdisciplinary management of complex chronic ulcers using vacuum assisted closure therapy and “buried chip skin grafts”, Zentralbl Chir, 131, S170, 10.1055/s-2006-921460 · DOI
  56. Slovut, 2008, Critical limb ischemia: medical and surgical management, Vasc Med, 13, 281, 10.1177/1358863X08091485 · DOI
  57. Marston, 2006, Natural history of limbs with arterial insufficiency and chronic ulceration treated without revascularization, J Vasc Surg, 44, 108, 10.1016/j.jvs.2006.03.026 · DOI
  58. Romiti, 2008, Meta-analysis of infrapopliteal angioplasty for chronic critical limb ischemia, J Vasc Surg, 47, 975, 10.1016/j.jvs.2008.01.005 · DOI
  59. Rivolta, 2008, Two-stage treatment for diabetic foot: surgical peripheral revascularization and minor amputation in day-surgery admission, Int J Surg, 6, S75, 10.1016/j.ijsu.2008.12.015 · DOI
  60. Takahashi, 2004, Wound care for elderly patients: advances and clinical applications for practicing physicians, Mayo Clin Proc, 79, 260, 10.4065/79.2.260 · DOI
  61. Horch, 2008, Coverage of exposed bones and joints in critically ill patients: lower extremity salvage with topical negative pressure therapy, J Cutan Med Surg, 12, 223, 10.2310/7750.2008.07073 · DOI
  62. Lerman, 2010, The SNaP Wound Care System: a case series using a novel ultraportable negative pressure wound therapy device for the treatment of diabetic lower extremity wounds, J Diabetes Sci Technol, 4, 825, 10.1177/193229681000400409 · DOI
  63. Vuerstaek, 2006, State-of-the-art treatment of chronic leg ulcers: a randomized controlled trial comparing vacuum-assisted closure (V.A.C.) with modern wound dressings, J Vasc Surg, 44, 1029, 10.1016/j.jvs.2006.07.030 · DOI
  64. Reeder, 2009, An extremely painful ulcer on the lower leg; Martorell arteriolosclerotic ulcer, Ned Tijdschr Geneeskd, 153, B421
  65. Sposato, 2001, Ambulant vacuum-assisted closure of skin-graft dressing in the lower limbs using a portable mini-VAC device, Br J Plast Surg, 54, 235, 10.1054/bjps.2000.3537 · DOI
  66. Aust, 2008, Lower limb revascularisation preceding surgical wound coverage – an interdisciplinary algorithm for chronic wound closure, J Plast Reconstr Aesthet Surg, 61, 925, 10.1016/j.bjps.2007.09.060 · DOI
  67. Lejay, 2008, Current clinical applications of vacuum-assisted closure (VAC) in vascular surgery, J Mal Vasc, 33, 196, 10.1016/j.jmv.2008.08.002 · DOI
  68. Nishimura, 2009, Vacuum-assisted closure for bilateral severe ischemic foot after revascularization: a case report, Int Angiol, 28, 340
  69. Inaba, 2007, Recent trends in bypass surgery performed in patients with critical limb ischemia, Nippon Geka Gakkai Zasshi, 108, 199
  70. Rajan, 2009, Quality improvement guidelines for percutaneous management of acute limb ischemia, J Vasc Interv Radiol, 20, S208, 10.1016/j.jvir.2009.04.010 · DOI
  71. O’Meara, 2009, Compression for venous leg ulcers, Cochrane Database System Rev, 1, 10.1002/14651858.CD000265.pub2 · DOI
  72. Khashram, 2009, Effect of TNP on the microbiology of venous leg ulcers: a pilot study, J Wound Care, 18, 164, 10.12968/jowc.2009.18.4.41608 · DOI
  73. Kieser, 2011, Negative pressure wound therapy as an adjunct to compression for healing chronic venous ulcers, J Wound Care, 20, 35, 10.12968/jowc.2011.20.1.35 · DOI
  74. Gibbs, 2006, Autologous full-thickness skin substitute for healing chronic wounds, Br J Dermatol, 155, 267, 10.1111/j.1365-2133.2006.07266.x · DOI
  75. Lorée, 2004, Is vacuum assisted closure a valid technique for debriding chronic leg ulcers?, J Wound Care, 13, 249, 10.12968/jowc.2004.13.6.26629 · DOI
  76. Kairinos, 2009, Negative-pressure wound therapy I: the paradox of negative-pressure wound therapy, Plast Reconstr Surg, 123, 589, 10.1097/PRS.0b013e3181956551 · DOI
  77. Llanos, 2006, Effectiveness of negative pressure closure in the integration of split thickness skin grafts: a randomized, double-masked, controlled trial, Ann Surg, 244, 700, 10.1097/01.sla.0000217745.56657.e5 · DOI
  78. Moisidis, 2004, A prospective, blinded, randomized, controlled clinical trial of topical negative pressure use in skin grafting, Plast Reconstr Surg, 114, 917, 10.1097/01.PRS.0000133168.57199.E1 · DOI
  79. Scherer, 2002, The vacuum assisted closure device: a method of securing skin grafts and improving graft survival, Arch Surg, 137, 930, 10.1001/archsurg.137.8.930 · DOI
  80. Vidrine, 2005, A comparison of negative-pressure dressings versus Bolster and splinting of the radial forearm donor site, Otolaryngol Head Neck Surg, 133, 403, 10.1016/j.otohns.2005.04.028 · DOI
  81. Körber, 2008, Vacuum assisted closure device improves the take of mesh grafts in chronic leg ulcer patients, Dermatology, 216, 250, 10.1159/000112937 · DOI
  82. Stetter, 2006, Skin grafting of a chronic leg ulcer with combined Versajet-V.A.C. therapy, J Dtsch Dermatol Ges, 4, 739, 10.1111/j.1610-0387.2006.06034.x · DOI
  83. Dorafshar, 2011, Prospective randomized study comparing gauze suction negative pressure wound therapy with standard vacuum assisted closure device, Ann Plast Surg, 10.1097/SAP.0b013e318221286c · DOI
  84. Birke-Sorensen, 2011, Evidence-based recommendations for negative pressure wound therapy: Treatment variables (pressure levels, wound filler and contact layer) - Steps towards an international consensus, J Plast Reconstr Aesthet Surg, 64

Cited by

Sorted by citations

See all 86

Metadata

Authors
Vig, S., Dowsett, C., Berg, L., Caravaggi, C., Rome, P., Birke-Sorensen, H., Bruhin, A., Chariker, M., Depoorter, M., Dunn, R., Duteille, F., Ferreira, F., Francos Martínez, J. M., Grudzien, G., Hudson, D., Ichioka, S., Ingemansson, R., Jeffery, S., Krug, E., Lee, C., Malmsjo, M., Runkel, N., Martin, R., & Smith, J.
Venue
Journal of Tissue Viability
Publisher
Elsevier BV
Published
2011-12
Volume
20
Pages
S1-S18
ISSN
0965-206X
DOI
10.1016/j.jtv.2011.07.002
Cited by
86
References
0
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Evidence-based recommendations for the use of negative pressure wound therapy in chronic wounds: Steps towards an international consensus. https://app.cochat.ai/papers/10.1016/j.jtv.2011.07.002
The paper
Vig, S., Dowsett, C., Berg, L., Caravaggi, C., Rome, P., Birke-Sorensen, H., Bruhin, A., Chariker, M., Depoorter, M., Dunn, R., Duteille, F., Ferreira, F., Francos Martínez, J. M., Grudzien, G., Hudson, D., Ichioka, S., Ingemansson, R., Jeffery, S., Krug, E., . . . Smith, J. (2011). Evidence-based recommendations for the use of negative pressure wound therapy in chronic wounds: Steps towards an international consensus. Journal of Tissue Viability. https://doi.org/10.1016/j.jtv.2011.07.002