The DOI matches its Crossref record; 215 of the 215 references it cites were found in a registry or an index.
AKI on CKD: heightened injury, suppressed repair, and the underlying mechanisms
Open accessAbstract
Acute kidney injury (AKI) and chronic kidney disease (CKD) are inter-connected. While AKI-to-CKD transition has been intensively studied, the information of AKI on CKD is very limited. Nonetheless, AKI, when occurring in CKD patients, is known to be more severe and difficult to recover. CKD is associated with significant changes in cell signaling in kidney tissues, including the activation of TGF-β, p53, HIF, and major developmental pathways. At the cellular level, CKD is characterized by mitochondrial dysfunction, oxidative stress, and aberrant autophagy. At the tissue level, CKD is characterized by chronic inflammation and vascular dysfunction. These pathological changes may contribute to the heightened sensitivity of, and non-recovery from, AKI in CKD patients.
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Cites
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Self-citationAcute Kidney Injury and Chronic Kidney Disease as Interconnected Syndromes
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Cited by
Zhao, M., Wang, Y., Li, L., Liu, S., Wang, C., Yuan, Y., Yang, G., Chen, Y., Cheng, J., Lu, Y., et al. (2021) · Theranostics · doi:10.7150/thno.50905 · Cited by 820
Self-citationCalzavacca, P., Licari, E., & Bellomo, R. (2010) · Surgical Intensive Care Medicine · doi:10.1007/978-0-387-77893-8_38 · Cited by 533
Immune cells and inflammation in AKI to CKD progression
Sato, Y., & Yanagita, M. (2018) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00195.2018 · Cited by 273
Endoplasmic reticulum stress is activated in post-ischemic kidneys to promote chronic kidney disease
Shu, S., Zhu, J., Liu, Z., Tang, C., Cai, J., & Dong, Z. (2018) · EBioMedicine · doi:10.1016/j.ebiom.2018.10.006 · Cited by 155
Self-citationMitophagy in Acute Kidney Injury and Kidney Repair
Wang, Y., Cai, J., Tang, C., & Dong, Z. (2020) · Cells · doi:10.3390/cells9020338 · Cited by 130
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Metadata
- Authors
- He, L., Wei, Q., Liu, J., Yi, M., Liu, Y., Liu, H., Sun, L., Peng, Y., Liu, F., Venkatachalam, M. A., & Dong, Z.
- Venue
- Kidney International
- Publisher
- Elsevier BV
- Published
- 2017-11
- Volume
- 92
- Issue
- 5
- Pages
- 1071-1083
- ISSN
- 0085-2538 (ISSN-L)
- OpenAlex
- W2753916497
- Cited by
- 448
- References
- 215
- FWCI
- 26.13
- Type
- journal article
- Language
- en
- Open access
- bronze
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- He, L., Wei, Q., Liu, J., Yi, M., Liu, Y., Liu, H., Sun, L., Peng, Y., Liu, F., Venkatachalam, M. A., & Dong, Z. (2017). AKI on CKD: heightened injury, suppressed repair, and the underlying mechanisms. Kidney International. https://doi.org/10.1016/j.kint.2017.06.030
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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