Mechanism of intranasal drug delivery directly to the brain

Cited by (721)

Items 401–500 of 721

  1. Advances in cell-penetrating peptide-based nose-to-brain drug delivery systems
    Shuai Hong, Jinyou Piao, Junsheng Hu, Xinyu Liu, Jing Xu, Heying Mao, Jingshu Piao, Jingshu Piao · 2025 · International Journal of Pharmaceutics
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  3. Gut to brain: essential micronutrient and trace element manganese transport, function and toxicity
    Jiaqi Zou, Riya Yerramilli, Tolunay Beker Aydemir · 2025 · Frontiers in Physiology
  4. Age-Related Macular Degeneration Treated with Autologous TelomerasePositive Totipotent Stem Cells
    Warren Young, Mark O Speight · 2020 · Stem Cell & Regenerative Medicine
  5. Nose-to-brain delivery of biologics and stem cells
    Mukta Agrawal, Aditya Narayan Konwar, Amit Alexander, Vivek B. Borse · 2021 · Elsevier eBooks
  6. Translational Considerations in the Development of Intranasal Treatments for Epilepsy
    Richard N. Prentice, Shakila B. Rizwan · 2023 · Pharmaceutics
  7. Niosomes-Based Drug Delivery in Targeting the Brain Tumors Via Nasal Delivery
    Mahmoud Gharbavi, Sepideh Parvanian, Milad Parvinzad Leilan, Shabnam Tavangar, Maedeh Parchianlou, Ali Sharafi · 2023 · Springer eBooks
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  9. A Comprehensive Review on Nanomedicine: Promising Approach for Treatment of Brain Tumor through Intranasal Administration
    Shiv Bahadur, Anubhav Prakash · 2022 · Current Drug Targets
  10. Intranasal dopamine attenuates fear responses induced by electric shock to the foot and by electrical stimulation of the dorsal periaqueductal gray matter
    Milene Cristina de Carvalho, Rebeca Machado de Figueiredo, Norberto Cysne Coimbra, Christie Ramos Andrade Leite‐Panissi, Maria A. de Souza Silva, Joseph P. Huston, Claudia Mattern, Marcus Lira Brandão · 2019 · Journal of Psychopharmacology
  11. Lipid nanocapsules: A Novel Strategy for Brain Targeting via Nasal Administration
    Mennatullah M. Ibrahim, Emad B. Basalious, Mohamed El- Nabarawi, Amal I. A. Makhlouf · 2024 · Journal of Research in Pharmacy
  12. Optimized mucus adhesion and penetration of lipid-polymer nanoparticles enables effective nose-to-brain delivery of perillyl alcohol for glioblastoma therapy
    Edilson Ribeiro de Oliveira, Jonathan Matheus Silva, Mariana Arraes Salomão, Nathalia Oliveira, C. Freitas, Natália Noronha Ferreira, Natália Sanchez Moreno, Camila Fernanda Rodero, Daniel Graziani, Valtencir Zucolotto et al. · 2025 · Drug Delivery and Translational Research
  13. Intranasal delivery route for neurodegenerative diseases: recent insights and future directions
    Jorge Daniel Correale, Vanesa Soledad Mattera, Juana Maria Pasquini · 2025 · Drug Delivery and Translational Research
  14. Nanoparticles Navigating the Intranasal Route: Innovative Approaches in Neurodegenerative Diseases
    Fabiola V. Borbolla‐Jiménez, Stephany Celeste Gutiérrez-Ruíz, Héctor Hernández‐Parra, Sheila I. Peña‐Corona, Aura Tamez-González, Ricardo D. Rivas-Amores, Jonathan J. Magaña, Gerardo Leyva‐Gómez · 2025 · Journal of Nanotechnology
  15. Quantum dots in neurotheranostics for the treatment of Alzheimer’s disease
    Tripti Sharma, Bushra Bashir, Prince Sharma, Nandani andotra, Sachin Kumar Singh, Thakur Gurjeet Singh, Sukriti Vishwas · 2025 · Ageing Research Reviews
  16. Mechanisms of oral microflora in Parkinson's disease
    Bingbing Wang, Can Martin Zhang, Caizhen Shi, Tianyu Zhai, Jinghui Zhu, Dongmin Wei, Juan Shen, Zehao Liu, Kunpeng Jia, Lin Zhao · 2024 · Behavioural Brain Research
  17. Biomimetic extracellular vesicles derived from chimeric antigen receptor monocytes to treat glioblastoma: An efficient and safe intranasal drug delivery nanoplatform
    Qihong Cheng, Minjie Wang, Zijie Zhou, Huitang Xia, Shaojie Yu, Jianglin Zheng, Kai Zhu, Xudong Li, Xuan Wang, Tao Xin et al. · 2025 · Bioactive Materials
  18. Targeting the brain: various approaches and science involved
    Sanjib Bahadur, Tripti Naurange, Pragya Baghel, Manisha Sahu, Kamesh Yadu · 2020 · ScienceRise Pharmaceutical Science
  19. Repurposing benzimidazoles to fight Cryptococcus
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  20. Advances in clinical translation of stem cell-based therapy in neurological diseases
    Yu Wang, Yirong Cao, Wan-Qing Xie, Yun-Lu Guo, Jiayi Cai, Ting-Ting Huang, Pei-Ying Li · 2025 · Journal of Cerebral Blood Flow and Metabolism
  21. Intranasal and inhaled delivery systems for targeting circadian dysfunction in neurodegenerative disorders, perspective and future outlook
    Rhearne C. Ryan, Mathew N. Leslie, Patrick He, Paul Michael Young, Camilla M. Hoyos, Hui Xin Ong, Daniela Traini · 2025 · Advanced Drug Delivery Reviews
  22. Role of natural plant extracts and hyaluronic acid derivatives in intranasal strategies for brain delivery. A review
    Khadija Boualam, Stefania Scialla, Ines Fasolino, Teresa Russo, Edoardo Scarpa, Noemi De Cesare, Vincenzo Guarino, R. De Santis, Mansour Sobeh, Noamane Taarji et al. · 2025 · International Journal of Biological Macromolecules
  23. Recent Advances in Donepezil Delivery Systems via the Nose-to-Brain Pathway
    Jiyoon Jon, Jieun Jeong, Joohee Jung, Hyosun Cho, Kyoung Song, Eun‐Sook Kim, Sang Hyup Lee, Eunyoung Han, Woo‐Hyun Chung, Aree Moon et al. · 2025 · Pharmaceutics
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  25. Overcoming barriers: nanomedicine-based strategies for nose-to-brain delivery
    West Kristian D. Paraiso, Carlos Palacín Ramos, Parisa Mishal Hossain, Carla Alvarez Gordi, Pablo Adrian Guillen-Poza, Sebastián Zagmutt, Sabina Quader, Rosalía Rodríguez‐Rodríguez · 2025 · Nanoscale
  26. Formulation considerations in enhancing olfactory mucosal deposition for nose-to-brain drug delivery
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  27. Comparative pharmacokinetic and intracerebral distribution of MDMB‐4F‐BICA in mice following inhalation (‘vapor’) and subcutaneous injection
    Yawen Xu, Xiangyu Li, Peng Xu, Fang Yan, Dan Wang · 2024 · Journal of Pharmaceutical and Biomedical Analysis
  28. Behavioral and neuropathological features of Alzheimer’s disease are attenuated in 5xFAD mice treated with intranasal GHK peptide
    Matthew Tucker, Gerald Yu Liao, Addison Keely, Joo Young Park, Manuela Rosenfeld, Jackson Wezeman, Ruby Mangalindan, Dan Ratner, Martin Darvas, Warren Ladiges · 2024 · Aging Pathobiology and Therapeutics
  29. Pharmacokinetics in Rat of P8, a Peptide Drug Candidate for the Treatment of Alzheimer’s Disease: Stability and Delivery to the Brain
    Nazneen N. Dewji, Marc R. Azar, Leah R. Hanson, William H. Frey, Bruce H. Morimoto, David Johnson · 2018 · Journal of Alzheimer s Disease Reports
  30. Behavioural effects of inhalation exposure to dizocilpine (MK-801) in mice
    Hiroshi Ueno, Shunsuke Suemitsu, Shinji Murakami, Naoya Kitamura, Kenta Wani, Yu Takahashi, Yosuke Matsumoto, Motoi Okamoto, Takeshi Ishihara · 2019 · Biomedicine & Pharmacotherapy
  31. Delivery of acetaminophen to the central nervous system and the pharmacological effect after intranasal administration with a mucoadhesive agent and absorption enhancer
    Kaho Ogawa, Masaki Uchida, Tsutomu Yamaki, Hirokazu Matsuzaki, Mitsutoshi Kimura, Mari Okazaki, Hiroyuki Uchida, Hideshi Natsume · 2020 · International Journal of Pharmaceutics
  32. Intranasal levosimendan prevents cognitive dysfunction and apoptotic response induced by repeated isoflurane exposure in newborn rats
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  33. Bone marrow mesenchymal stem cells improve cognitive impairments induced by methamphetamine in rats and reduce relapse
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  34. Increased alpha‐synuclein and neuroinflammation in the substantia nigra triggered by systemic inflammation are reversed by targeted inhibition of the receptor for advanced glycation end products ( RAGE )
    Daniel Oppermann Peixoto, Reykla Ramon Bittencourt, Juciano Gasparotto, Flávio Gabriel Carazza Kessler, Pedro Ozório Brum, Nauana Somensi, Carolina Saibro Girardi, Lucas dos Santos da Silva, Tiago F. Outeiro, José Cláudio Fonseca Moreira et al. · 2023 · Journal of Neurochemistry
  35. Nose-to Brain Delivery of Resveratrol, a Non-Invasive Method for the Treatment of Cerebral Ischemia
    Iván Alquisiras-Burgos, Irma Gabriela González-Herrera, Sergio Alcalá-Alcalá, Penélope Aguilera · 2024 · Drugs and Drug Candidates
  36. Application of biomaterials in the treatment of intracerebral hemorrhage
    Wei Wang, Xiaowen Liu, Yupeng Wang, Dongfang Zhou, Lukui Chen · 2024 · Biomaterials Science
  37. Design of enkephalin modifications protected from brain extracellular peptidases providing long-term analgesia
    Ekaterina S. Kropotova, Irina Sergeevna Ivleva, Marina N. Karpenko, Mark I. Mosevitsky · 2019 · Bioorganic & Medicinal Chemistry
  38. Navigating into the Paradigm of Nose-to-brain Delivery of Nanotherapeutics and their Repurposing as Nanotheranostics for Neurodegenerative Diseases
    Asad Ali, Nasr Ali Emad, Niha Sultana, Ayesha Waheed, Mohd. Aqil, Yasmin Sultana, Mohd Mujeeb · 2024 · CNS & Neurological Disorders - Drug Targets
  39. Nose-to-Brain Targeting of Resveratrol Nanoformulations
    Amir Bavafa, Sajad Sahab Negah, Fatemeh Forouzanfar · 2025 · Current Vascular Pharmacology
  40. Transnasal PLGA Nanoparticles with Terpene Permeation Enhancers: Membrane Remodeling and Tight Junction Modulation for Enhanced Brain Drug Delivery
    Yi Zhang, Zishuo Guo, Haitong Zhang, Hongmei Wei, Tieshan Wang, Shouying Du, Pengyue Li · 2025 · International Journal of Molecular Sciences
  41. Insulin resistance: fueling oxidative stress and neurodegeneration
    Laia Berridi Chamorro, Barbara Zulli, Eugenio Barone · 2025 · Journal of Neural Transmission
  42. Receptor-mediated nose-to-brain delivery of drug combination-loaded polymeric nanocarriers for the treatment of glioblastoma- current progress and future perspectives part I: receptor-mediated nose-to-brain delivery approaches for glioblastoma
    Zufika Qamar, Saif Ahmad Khan, Pallavi Kumari, Mariya Khan, Pushadapu Veera Venkata Siva Krishna, Shweta Dang, Sanjula Baboota, Asgar Ali, Javed Ali · 2025 · Expert Opinion on Drug Delivery
  43. Intranasal drug delivery: Unlocking the nose-to-brain route for central nervous system therapies
    Ban Alwali, Thaigarajan Parumasivam, Moawia M. Al-Tabakha · 2026 · International Journal of Pharmaceutics X
  44. Nanotechnology-driven Microemulsion Based Intranasal Delivery to Neurotechnology-driven Neuralink: Strategies to Improve Management of Neurodegenerative Disorders
    Pragya, Shradha Bisht, Poonam Parashar · 2024 · AAPS PharmSciTech
  45. Dodecyl creatine ester, a promising treatment to deliver creatine to neurons, achieves pharmacology efficacy in creatine transporter deficiency
    Clémence Disdier, Clara Lhotellier, Anne-Cécile Guyot, Narciso Costa, Frédéric Théodoro, Alain Pruvost, Matthew R. Skelton, Thomas Joudinaud, Aloïse M Mabondzo, Henri Bénech · 2024 · European Journal of Medicinal Chemistry
  46. Nose-to-brain delivery of human muse cells enhances structural and functional recovery in the murine ischemic stroke model
    Shusuke Yamamoto, Keitaro Shiraishi, Yoshihiro Kushida, Yo Oguma, Shohei Wakao, Mari Dezawa, Satoshi Kuroda · 2025 · Scientific Reports
  47. Pharmacokinetics and pharmacodynamics of intranasal insulin in a rat brain
    Jelena Osmanović Barilar, Leonarda Vlahov, Ana Babić Perhoč, Jan Homolak, Davor Virag, Eugenio Barone, Melita Šalković‐Petrišić, Ana Knezović · 2025 · British Journal of Pharmacology
  48. Acute intranasal dopamine application counteracts the reversal learning deficit of spontaneously hypertensive rats in an attentional set-shifting task
    Jay‐Shake Li, Shan-Sung Yang, Joseph P. Huston, Owen Yuan-Hsin Chao, Yi Yang, Claudia Mattern · 2021 · Psychopharmacology
  49. Drug repositioning of benzimidazole anthelmintics in the treatment of cryptococcosis: a review
    Emanuel Almeida Moreira de Oliveira, Gabriella Freitas Ferreira, Karen Luise Lang · 2021 · Medicinal Chemistry Research
  50. Investigational drugs for the treatment of olfactory dysfunction
    Arianna Di Stadio, Cinzia Severini, Andrea Colizza, Marco DE VINCENTIIS, Ignazio La Mantia · 2022 · Expert Opinion on Investigational Drugs
  51. Rodent Model Preclinical Assessment of PEGylated Block Copolymer Targeting Cognition and Oxidative Stress Insults of Alzheimer’s Disease
    Sutapa Som Chaudhury, Mridula Nandi, Krishna G. Kumar, Bhuban Ruidas, Tapas Kumar Sur, Parash Prasad, Saikat Chakrabarti, Priyadarsi De, Jaya Sil, Chitrangada Das Mukhopadhyay · 2023 · Molecular Neurobiology
  52. Routes of Nano-drug Administration and Nano-based Drug Delivery System and Toxicity
    Boobalan Gopu, Ramajayan Pandian, Angayarkanni Sevvel, Sanket K. Shukla · 2023 · Springer eBooks
  53. Exploring the potential of intranasal drug delivery systems in the management of hypertension
    Rinada H. Hassan, Heba A. Gad, Dalia S. Shaker, Rania A.H. Ishak · 2023 · RPS Pharmacy and Pharmacology Reports
  54. Caffeine inhalation effects on locomotor activity in mice
    Hiroshi Ueno, Yu Takahashi, Shunsuke Suemitsu, Shinji Murakami, Naoya Kitamura, Kenta Wani, Yosuke Matsumoto, Motoi Okamoto, Takeshi Ishihara · 2020 · Drug Development and Industrial Pharmacy
  55. Pre-referral intranasal artesunate powder for cerebral malaria: a proof-of-concept study
    Yobouet Inès Kouakou, Aurélien Millet, Élodie Fromentin, Nathalie Hauchard, Gonçalo Farias, M. Fieux, Aurélie Coudert, Roukayatou Omorou, Ibrahim Bin Said, Adeline Lavoignat et al. · 2022 · Malaria Journal
  56. Intranasal Analgesia in Preterm and Term Neonates
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  57. Outer radial glia promotes white matter regeneration after neonatal brain injury
    Hideo Jinnou, Lauren M. Rosko, Satoshi Yamashita, Soichiro Henmi, Jaya D. Prasad, Van K. Lam, Artur Agaronyan, Tsang‐Wei Tu, Yuka Imamura, Kazuya Kuboyama et al. · 2025 · Cell Reports Medicine
  58. Intranasal drug delivery Dynamics: Extracellular and intracellular pathways revealed by Fluoro-Gold tracer in a mouse model
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  59. Breaking the brain barrier: Hybrid nanoparticle-enabled delivery for next-gen neurotherapeutics
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  60. Intranasal delivery of drug-loaded polymeric nanomicelles for brain targeting: a comprehensive review
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  61. Computational Fluid Dynamics Approach for Direct Nose-to-Brain Drug Delivery: A Systematic Review and Meta-Analysis
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  63. Formulation and characterization of dolutegravir sodium-loaded nanostructured lipid carrier in situ gel for targeted brain delivery via intranasal route
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  64. Current advances in nose to brain drug delivery
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  68. Optimization of Eudragit RS100 Nanocapsule Formulation for Encapsulating Perillyl Alcohol and Temozolomide Using Design of Experiments
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