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Age-related gene-specific changes of A-to-I mRNA editing in the human brain
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“Aging is associated with an increase in transcriptional noise (Bahar et al., 2006), and an aberrant production and maturation of many mRNAs (Harries et al., 2011; Nicholas et al., 2010).”
From The Hallmarks of Aging (2013) · cites this paper as Nicholas et al., 2010
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Research works printed but not linked: 27
- Akabas MH Ronald JB 2004 GABAA Receptor Structure-Function Studies: A Reexamination in Light of New Acetylcholine Receptor Structures International Review of Neurobiology Academic Press 1 43 15530567
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- Carlson NG Howard J Gahring LC Rogers SW 2000 RNA editing (Q/R site) and flop/flip splicing of AMPA receptor transcripts in young and old brains Neurobiol Aging 21 599 606 10924778
- Cenci C Barzotti R Galeano F Corbelli S Rota R Massimi L Di Rocco C O’Connell MA Gallo A 2008 Down-regulation of RNA editing in pediatric astrocytomas: ADAR2 editing activity inhibits cell migration and proliferation J Biol Chem 18178553
- Gurevich I Tamir H Arango V Dwork AJ Mann JJ Schmauss C 2002 Altered editing of serotonin 2C receptor pre-mRNA in the prefrontal cortex of depressed suicide victims Neuron 34 349 356 11988167
- Higuchi K Kitagawa K Kogishi K Takeda T 1992 Developmental and age-related changes in apolipoprotein B mRNA editing in mice J Lipid Res 33 1753 1764 1479285
- Jackson RS 2nd Cho YJ Stein S Liang P 2007 CYFIP2, a direct p53 target, is leptomycin-B sensitive Cell Cycle 6 95 103 17245118
- Kawahara Y Zinshteyn B Sethupathy P Iizasa H Hatzigeorgiou AG Nishikura K 2007 Redirection of Silencing Targets by Adenosine-to-Inosine Editing of miRNAs Science 315 1137 1140 17322061 PMC2953418
- Kim DD Kim TT Walsh T Kobayashi Y Matise TC Buyske S Gabriel A 2004 Widespread RNA editing of embedded alu elements in the human transcriptome Genome Res 14 1719 1725 15342557 PMC515317
- Levanon EY Eisenberg E Yelin R Nemzer S Hallegger M Shemesh R Fligelman ZY Shoshan A Pollock SR Sztybel D 2004 Systematic identification of abundant A-to-I editing sites in the human transcriptome Nat Biotechnol 22 1001 1005 15258596
- Li JB Levanon EY Yoon JK Aach J Xie B Leproust E Zhang K Gao Y Church GM 2009 Genome-wide identification of human RNA editing sites by parallel DNA capturing and sequencing Science 324 1210 1213 19478186
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- Maas S Patt S Schrey M Rich A 2001 Underediting of glutamate receptor GluR-B mRNA in malignant gliomas Proc Natl Acad Sci U S A 98 14687 14692 11717408 PMC64742
- Morse DP Bass BL 1999 Long RNA hairpins that contain inosine are present in Caenorhabditis elegans poly(A)+ RNA Proc Natl Acad Sci U S A 96 6048 6053 10339539 PMC26833
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- Niswender CM Herrick-Davis K Dilley GE Meltzer HY Overholser JC Stockmeier CA Emeson RB Sanders-Bush E 2001 RNA editing of the human serotonin 5-HT2C receptor. alterations in suicide and implications for serotonergic pharmacotherapy Neuropsychopharmacology 24 478 491 11282248
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Cited by
Sorted by citations
López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013) · Cell · doi:10.1016/j.cell.2013.05.039 · Cited by 14,982
The epigenetics of aging and neurodegeneration
Lardenoije, R., Iatrou, A., Kenis, G., Kompotis, K., Steinbusch, H. W. M., Mastroeni, D., Coleman, P., Lemere, C. A., Hof, P. R., van den Hove, D. L. A., et al. (2015) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.05.002 · Cited by 381
Metadata
- Authors
- Nicholas, A., de Magalhaes, J. P., Kraytsberg, Y., Richfield, E. K., Levanon, E. Y., & Khrapko, K.
- Venue
- Mechanisms of Ageing and Development
- Publisher
- Elsevier BV
- Published
- 2010-06
- Volume
- 131
- Issue
- 6
- Pages
- 445-447
- ISSN
- 0047-6374
- PMC
- PMC2915444
- Cited by
- 48
- References
- 0
- Language
- en
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