The epigenetics of aging and neurodegeneration

Initial sequencing and analysis of the human genome

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Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

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The Amyloid Hypothesis of Alzheimer’s Disease: Progress and Problems on the Road to Therapeutics

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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

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Chromatin modifications and their function

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The functions of animal microRNAs

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Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy

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Translating the Histone Code

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Crystal structure of the nucleosome core particle at 2.8 Å resolution

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Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

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Alzheimer's disease: the amyloid cascade hypothesis

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DNA methylation age of human tissues and cell types

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High-Resolution Profiling of Histone Methylations in the Human Genome

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Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

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Epigenetic programming by maternal behavior

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DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development

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MicroRNAs: small RNAs with a big role in gene regulation

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Lanthanum Chloride Inhibits LPS Mediated Expressions of Pro-Inflammatory Cytokines and Adhesion Molecules in HUVECs: Involvement of NF-κB-Jmjd3 Signaling

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Parkinson's disease: clinical features and diagnosis

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A bivalent chromatin structure marks key developmental genes in embryonic stem cells

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Landscape of transcription in human cells

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Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

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Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

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Overdependence on degraded gist memory in Alzheimer's disease.

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Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

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Human DNA methylomes at base resolution show widespread epigenomic differences

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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

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N6-methyladenosine-dependent regulation of messenger RNA stability

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α-Synuclein Locus Triplication Causes Parkinson's Disease

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NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

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Resveratrol improves health and survival of mice on a high-calorie diet

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Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

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Epidemiology of Parkinson's disease

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N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

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Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

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Silencing of microRNAs in vivo with ‘antagomirs’

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The Free Radical Theory of Aging Matures

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Epigenetic differences arise during the lifetime of monozygotic twins

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ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

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Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclassesPreprint

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Protein aggregation and neurodegenerative disease

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Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

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Non-coding RNAs and cancer: microRNAs and beyond

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2013 Alzheimer's disease facts and figures

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Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

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Regulation of mRNA Translation and Stability by microRNAs

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A protein factor essential for microtubule assembly

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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

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DNA methylation landscapes: Provocative insights from epigenomics

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<i>TREM2</i> Variants in Alzheimer's Disease

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Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

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Epigenetic modifications and human disease

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Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA

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The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

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Neuropathological Classification of Huntingtonʼs Disease

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RNA Maps Reveal New RNA Classes and a Possible Function for Pervasive Transcription

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Genomic DNA methylation: the mark and its mediators.

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Neurodegenerative Tauopathies

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Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase

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Epigenetic memory in induced pluripotent stem cells

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ATP-citrate lyase links cellular metabolism to histone acetylation

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Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

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Histone methylation: a dynamic mark in health, disease and inheritance

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Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

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The Drosha-DGCR8 complex in primary microRNA processingPreprint

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Mammalian Sirtuins: Biological Insights and Disease Relevance

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Decreased Clearance of CNS β-Amyloid in Alzheimer’s Disease

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DNA Methylation and Gene Function

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Structural and molecular interrogation of intact biological systems

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Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

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Genome-wide association study reveals genetic risk underlying Parkinson's disease

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Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

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Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

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HDAC2 negatively regulates memory formation and synaptic plasticity

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