HMGB1 in health and disease

Kang, Rui, Chen, Ruochan, Zhang, Qiuhong, Hou, Wen, Wu, Sha, Cao, Lizhi, Huang, Jin, Yu, Yan +10 more·2014·Molecular Aspects of Medicine

DOI 10.1016/j.mam.2014.05.001

Cites (1,874)

Items 401–600 of 1,874

TLR4‐mediated skin carcinogenesis is dependent on immune and radioresistant cells
Deepak Mittal, Fabiana Saccheri, Emilie Vénéreau, Tobias Pusterla, Marco Emilio Bianchi, María Rescigno · 2010 · The EMBO Journal
HMGB1 inhibits cell death in yeast and mammalian cells and is abundantly expressed in human breast carcinoma
Marie-Luise Brezniceanu, Kirsten Völp, Susanne Bösser, Christine Solbach, Peter Lichter, Stefan Joos, Martin Zörnig · 2003 · The FASEB Journal
High-mobility-group 1 protein mediates DNA bending as determined by ring closures.
Pieter M. Pil, Connie S. Chow, Stephen J. Lippard · 1993 · Proceedings of the National Academy of Sciences
Molecular Hydrogen Ameliorates Lipopolysaccharide-Induced Acute Lung Injury in Mice Through Reducing Inflammation and Apoptosis
Keliang Xie, Yonghao Yu, Yi Huang, Lina Zheng, Jipeng Li, Hongguang Chen, Huan-zhi Han, Lichao Hou, Gu Gong, Guolin Wang · 2012 · Shock
Molecular basis for the redox control of nuclear transport of the structural chromatin protein Hmgb1
George Hoppe, Katherine E. Talcott, Sanjoy K. Bhattacharya, John W. Crabb, Jonathan E. Sears · 2006 · Experimental Cell Research
Programmed necrosis, not apoptosis, is a key mediator of cell loss and DAMP-mediated inflammation in dsRNA-induced retinal degeneration
Yusuke Murakami, Hidetaka Matsumoto, Miin Roh, Andrea Giani, Keiko Kataoka, Yuki Morizane, Maki Kayama, Aristomenis Thanos, Shunji Nakatake, Shoji Notomi et al. · 2013 · Cell Death and Differentiation
High mobility group box chromosomal protein 1, a DNA binding cytokine, induces arthritis
Rille Pullerits, Ing‐Marie Jonsson, Margareta Verdrengh, Maria I Bokarewa, Ulf Andersson, Helena Erlandsson-Harris, Andrej Tarkowski · 2003 · Arthritis & Rheumatism
High Affinity Binding and Overlapping Localization of Neurocan and Phosphacan/Protein-tyrosine Phosphatase-ζ/β with Tenascin-R, Amphoterin, and the Heparin-binding Growth-associated Molecule
Peter Milev, Atsuro Chiba, Monika Häring, Heikki Rauvala, Melitta Schachner, Barbara Ranscht, Renée K. Margolis, Richard U. Margolis · 1998 · Journal of Biological Chemistry
Heme-Oxygenase-1 Induction and Carbon Monoxide-Releasing Molecule Inhibit Lipopolysaccharide (LPS)-Induced High-Mobility Group Box 1 Release in Vitro and Improve Survival of Mice in LPS- and Cecal Ligation and Puncture-Induced Sepsis Model in Vivo
Konstantin Tsoyi, Tae Yu Lee, Young Soo Lee, Hye Jung Kim, Han Geuk Seo, Jae Heun Lee, Ki Churl Chang · 2009 · Molecular Pharmacology
HMGB1 IS MARKEDLY ELEVATED WITHIN 6 HOURS OF MECHANICAL TRAUMA IN HUMANS
Erik D. Peltz, Ernest Eugene Moore, Phillip C. Eckels, Sagar S. Damle, Yuko Tsuruta, Jeffrey L. Johnson, Angela Sauaia, Christopher C. Silliman, Anirban M. Banerjee, Edward H Abraham · 2009 · Shock
High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease
David S. Pisetsky, Helena Erlandsson-Harris, Ulf Andersson · 2008 · Arthritis Research & Therapy
Bacterial endotoxin stimulates macrophages to release HMGB1 partly through CD14- and TNF-dependent mechanisms
Guoqian Chen, Jianhua Li, Mahendar Ochani, Beatriz Rendon-Mitchell, Xiaoling Qiang, Srinivas M. Susarla, Luis Ulloa, Huan Yang, Saijun Fan, Sanna M. Goyert et al. · 2004 · Journal of Leukocyte Biology
Cholinergic Anti-Inflammatory Pathway Activity and High Mobility Group Box-1 (HMGB1) Serum Levels in Patients with Rheumatoid Arthritis
Richard S. Goldstein, Annette N. Bruchfeld, Lihong Yang, Abdul Rashid Qureshi, Margot Gallowitsch‐Puerta, Nirav Bipin Patel, Brett J. Huston, Sangeeta S. Chavan, Mauricio Rosas‐Ballina, Peter K. Gregersen et al. · 2007 · Molecular Medicine
DAMPs activating innate and adaptive immune responses in COPD
Simon D. Pouwels, Irene H. Heijink, Nick H.T. ten Hacken, Peter Vandenabeele, Dmitri V. Krysko, Martijn C. Nawijn, Antoon J. M. van Oosterhout · 2013 · Mucosal Immunology
Discovery of a novel type of autophagy targeting RNA
Yuuki Fujiwara, Akiko Furuta, Hisae Kikuchi, Shu Aizawa, Yusuke Hatanaka, Chiho Konya, Kenko Uchida, Aya Yoshimura, Yoshitaka Tamai, Keiji Wada et al. · 2013 · Autophagy
High-mobility group box 1 (HMGB1)-toll-like receptor (TLR)4-interleukin (IL)-23-IL-17A axis in drug-induced damage-associated lethal hepatitis: Interaction of γδ T cells with macrophages
Xuefu Wang, Rui Sun, Haiming Wei, Zhigang Tian · 2012 · Hepatology
Antiinflammatory effects of matrine in LPS-induced acute lung injury in mice
Bo Zhang, Zhong-Yang Liu, Yanyan Li, Ying Luo, Man-Ling Liu, Haiying Dong, Yanxia Wang, Yi Liu, Pengtao Zhao, Faguang Jin et al. · 2011 · European Journal of Pharmaceutical Sciences
High Mobility Group Protein-1 Inhibits Phagocytosis of Apoptotic Neutrophils through Binding to Phosphatidylserine
Gang Liu, Jing Wang, Young-Jun Park, Yuko Tsuruta, Emmanuel Lorne, Xia Zhao, Edward H Abraham · 2008 · The Journal of Immunology
Activation of toll-like receptor, RAGE and HMGB1 signalling in malformations of cortical development
Zurolo, E., Iyer, A., Maroso, M., Carbonell, C., Anink, J. J., Ravizza, T., Fluiter, K., Spliet, W. G. M., van Rijen, P. C., Vezzani, A. et al. · 2011 · Brain
A human placental cDNA clone that encodes nonhistone chromosomal protein HMG-1
Lisa Wen, Jenq‐Kuen Huang, Barbara H. Johnson, R. Smith Gerald · 1989 · Nucleic Acids Research
TOX: an HMG box protein implicated in the regulation of thymocyte selection
Beverley Wilkinson, Jeff Y.-F. Chen, Peggy P. Han · 2002 · Nature Immunology
Interleukin-1 type 1 receptor/Toll-like receptor signalling in epilepsy: the importance of IL-1beta and high-mobility group box 1
Mattia Maroso, Silvia Balosso, Teresa Ravizza, J. Liu, Marco Emilio Bianchi, Annamaria Vezzani · 2011 · Journal of Internal Medicine
Smooth muscle cells in human atherosclerotic plaques secrete and proliferate in response to high mobility group box 1 protein
Annalisa Porto, Roberta Palumbo, Maurizio Pieroni, Gianfranco Aprigliano, Roberto Chiesa, Francesca Sanvito, Attilio Maseri, Marco Emilio Bianchi · 2006 · The FASEB Journal
HMGB1 and HMGB2 Cell-specifically Down-regulate the p53- and p73-dependent Sequence-specific Transactivation from the Human Bax Gene Promoter
Michal Štros, Toshinori Ozaki, Alena Bačı́ková, Hajime Kageyama, Akira Nakagawara · 2002 · Journal of Biological Chemistry
High-mobility group box-1 impairs memory in mice through both toll-like receptor 4 and Receptor for Advanced Glycation End Products
Andrey M. Mazarati, Mattia Maroso, Valentina Iori, Annamaria Vezzani, Mirjana Carli · 2011 · Experimental Neurology
Adenovirus Membrane Penetration Activates the NLRP3 Inflammasome
Arlene Barlan, Tina Griffin, Kathleen A. McGuire, Christopher M. Wiethoff · 2010 · Journal of Virology
Conditional ablation of HMGB1 in mice reveals its protective function against endotoxemia and bacterial infection
Hideyuki Yanai, Atsushi Matsuda, Jianbo An, Ryuji Koshiba, Junko Nishio, Hideo Negishi, Hiroaki Ikushima, Takashi Onoe, Hideki Ohdan, Nobuaki Yoshida et al. · 2013 · Proceedings of the National Academy of Sciences
HMGB1 Is Phosphorylated by Classical Protein Kinase C and Is Secreted by a Calcium-Dependent Mechanism
Young Joo Oh, Ju Ho Youn, Yeounjung Ji, Sang Eun Lee, Kook Jin Lim, Ji Eun Choi, Jeon‐Soo Shin · 2009 · The Journal of Immunology
Endogenous signals released from necrotic cells augment inflammatory responses to bacterial endotoxin
Rabab Elmezayen, Mohamed El Gazzar, Michael C. Seeds, Charles E. McCall, Stephen C. Dreskin, Mark Robert Nicolls · 2007 · Immunology Letters
DNA binding properties of an HMG1-related protein from yeast mitochondria.
John F.X. Diffley, Bruce Stillman · 1992 · Journal of Biological Chemistry
Role of high-mobility group box 1 protein in post-infarction healing process and left ventricular remodelling
Takashi Kohno, Toshihisa Anzai, Kanako Naito, Taku Miyasho, M. Okamoto, H. Yokota, Shingo Yamada, Yuichiro Maekawa, Toshiyuki Takahashi, Tsutomu Yoshikawa et al. · 2008 · Cardiovascular Research
Chromatin components as part of a putative transcriptional repressing complex
Norbert Lehming, Agnès Le Saux, Jutta Schüller, Mark Ptashne · 1998 · Proceedings of the National Academy of Sciences
The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein.
Hui Ge, Robert G. Roeder · 1994 · Journal of Biological Chemistry
EGCG stimulates autophagy and reduces cytoplasmic HMGB1 levels in endotoxin-stimulated macrophages
Wei Li, Shu Zhu, Jianhua Li, Andrei Assa, Arvin Jundoria, Jianying Xu, Saijun Fan, N. Tony Eissa, Kevin J. Tracey, Andrew E. Sama et al. · 2011 · Biochemical Pharmacology
Hypoxia-increased RAGE and P2X7R expression regulates tumor cell invasion through phosphorylation of Erk1/2 and Akt and nuclear translocation of NF-κB
Marco Tafani, Luana Schito, Laura Pellegrini, Lidia Villanova, Gabriella Marfè, Tahira Anwar, Roberta Rosa, Manuela Indelicato, Massimo Fini, Bruna Pucci et al. · 2011 · Carcinogenesis
WNT10B/β‐catenin signalling induces HMGA2 and proliferation in metastatic triple‐negative breast cancer
Peter Wend, Stephanie Runke, Korinna Wend, Brenda Anchondo, Maria N. Yesayan, Meghan L. Jardon, Natalie Hardie, Christoph Loddenkemper, Ilya V. Ulasov, Maciej S. Lesniak et al. · 2013 · EMBO Molecular Medicine
High hydrostatic pressure induces immunogenic cell death in human tumor cells
Jitka Palich Fucikova, Irena Kusova Moserova, Iva Truxová, Ivana Heřmanová, Irena Vančurová, Simona Partlová, Anna Fialová, Luděk Sojka, Pierre‐François Cartron, Milan Houška et al. · 2014 · International Journal of Cancer
Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis
Shaival H. Davé, Jeremy S. Tilstra, Katsuyoshi Matsuoka, Fengling Li, Richard DeMarco, Donna Beer–Stolz, Antonia R. Sepulveda, Mitchell P. Fink, Michael T. Lotze, Scott Eric Plevy · 2009 · Journal of Leukocyte Biology
Increased levels of HMGB1 and pro-inflammatory cytokines in children with febrile seizures
Jieun Choi, Hyun Jin Min, Jeon‐Soo Shin · 2011 · Journal of Neuroinflammation
ASC/caspase-1/IL-1β signaling triggers inflammatory responses by promoting HMGB1 induction in liver ischemia/reperfusion injury
Naoko Kamo, Bibo Ke, Amir A. Ghaffari, Xiu‐Da Shen, Ronald W. Busuttil, Genhong Cheng, Jerzy W. Kupiec‐Weglinski · 2013 · Hepatology
HMGB1 is a potent trigger of arthritis
Jan Andersson, Helena Erlandsson-Harris · 2004 · Journal of Internal Medicine
Structure of the A-Domain of HMG1 and Its Interaction with DNA as Studied by Heteronuclear Three- and Four-Dimensional NMR Spectroscopy
Colin H. Hardman, R. William Broadhurst, Andrew R. C. Raine, Klaus D. Grasser, Jean Olwen Thomas, Ernest D. Laue · 1995 · Biochemistry
Increased levels of ligands of Toll-like receptors 2 and 4 in type 1 diabetes
Sridevi Devaraj, Mohan R. K. Dasu, S. H. Park, Ishwarlal Jialal · 2009 · Diabetologia
High mobility group box 1 (HMGB1) and anti-HMGB1 antibodies and their relation to disease characteristics in systemic lupus erythematosus
Deena A Abdulahad, Johanna Westra, Johannes Bijzet, Pieter C. Limburg, Cees G. M. Kallenberg, Marc Bijl · 2011 · Arthritis Research & Therapy
HMGB1: The Central Cytokine for All Lymphoid Cells
Guanqiao Li, Xiaoyan Liang, Michael T. Lotze · 2013 · Frontiers in Immunology
Eosinophilic Granulocytes and Damage-associated Molecular Pattern Molecules (DAMPs)
Ramin Lotfi, James J. Lee, Michael T. Lotze · 2006 · Journal of Immunotherapy
Regulation of cell migration by amphoterin
Carole Fages, Riitta M. Nolo, Henri J. Huttunen, Eeva‐Liisa Eskelinen, Heikki Rauvala · 2000 · Journal of Cell Science
Signaling of High Mobility Group Box 1 (HMGB1) through Toll-like Receptor 4 in Macrophages Requires CD14
Sodam Kim, Sun Young Kim, John P. Pribis, Michael T. Lotze, Kevin Patrick Mollen, Richard A. Shapiro, Patricia Loughran, Melanie J. Scott, Timothy R. Billiar · 2013 · Molecular Medicine
The association of erythroblasts with macrophages promotes erythroid proliferation and maturation: a 30-kD heparin-binding protein is involved in this contact
Manjit Hanspal, JS Hanspal · 1994 · Blood
The expression of the receptor for advanced glycation endproducts (RAGE) is permissive for early pancreatic neoplasia
Kang, Rui, Loux, Tara, Tang, Daolin, Schapiro, Nicole E., Vernon, Philip, Livesey, Kristen M., Krasinskas, Alyssa, Lotze, Michael T., Zeh, Herbert J. · 2012 · Proceedings of the National Academy of Sciences
HMGB1 Is a Cofactor in Mammalian Base Excision Repair
Rajendra Prasad, Yuan Liu, Leesa J. Deterding, Vladimir P. Poltoratsky, Padmini S. Kedar, Julie K. Horton, Shin‐ichiro Kanno, Kenjiro Asagoshi, Esther W. Hou, Svetlana N. Khodyreva et al. · 2007 · Molecular Cell
The Structure of the Four-Way Junction in DNA
D.M.J. Lilley, Robert M. Clegg · 1993 · Annual Review of Biophysics and Biomolecular Structure
Persistent Hypomethylation in the Promoter of Nucleosomal Binding Protein 1 (Nsbp1) Correlates with Overexpression of Nsbp1 in Mouse Uteri Neonatally Exposed to Diethylstilbestrol or Genistein
Wan‐Yee Tang, Retha R. Newbold, Katerina Mardilovich, Wendy N. Jefferson, Robert Y.S. Cheng, Mario Medvedovic, Shuk‐Mei Ho · 2008 · Endocrinology
Evidence for a shared structural role for HMG1 and linker histones B4 and H1 in organizing chromatin.
Karl P. Nightingale, Stefan I. Dimitrov, Raymond Reeves, Alan P. Wolffe · 1996 · The EMBO Journal
HMGB1 as a predictor of organ dysfunction and outcome in patients with severe sepsis
Sari Karlsson, Ville Pettilä, Jyrki J. Tenhunen, Raili Laru‐Sompa, Marja S. Hynninen, Esko Ruokonen · 2008 · Intensive Care Medicine
Disulfide-Containing High Mobility Group Box-1 Promotes N -Methyl- d -Aspartate Receptor Function and Excitotoxicity by Activating Toll-Like Receptor 4-Dependent Signaling in Hippocampal Neurons
Silvia Balosso, Jaron Liu, Marco Emilio Bianchi, Annamaria Vezzani · 2013 · Antioxidants and Redox Signaling
Covalent modification of the homeodomain-interacting protein kinase 2 (HIPK2) by the ubiquitin-like protein SUMO-1
Young Ho Kim, Cheol Yong Choi, Yongsok Kim · 1999 · Proceedings of the National Academy of Sciences
HMGB1 is involved in autophagy inhibition caused by SNCA/α-synuclein overexpression
Ju‐Xian Song, Jiahong Lu, Liang‐Feng Liu, Leilei Chen, Siva Sundara Kumar Durairajan, Zhenyu Yue, Hongqi Zhang, Min Li · 2013 · Autophagy
High Mobility Group Box-1 (HMGB1) Participates in the Pathogenesis of Alcoholic Liver Disease (ALD)
Xiaodong Ge, Daniel James Antoine, Yongke Lu, Elena Arriazu, Tung-Ming Leung, Arielle L. Klepper, Andrea D. Branch, Maria Isabel Fiel, Natalia Nieto · 2014 · Journal of Biological Chemistry
On the presence of two new high mobility group‐like proteins in HeLa S3 cells
Terje Lund, Jostein Holtlund, Marianne Fredriksen, S. Laland · 1983 · FEBS Letters
Co-expression of receptor for advanced glycation end products and the ligand amphoterin associates closely with metastasis of colorectal cancer
Hiroki Kuniyasu, Yoshitomo Chihara, Tadateru Takahashi · 2003 · Oncology Reports
Receptor for Advanced Glycation Endproducts is upregulated in temporal lobe epilepsy and contributes to experimental seizures
Valentina Iori, Mattia Maroso, Massimo Rizzi, Anand M. Iyer, Roberta Vertemara, Mirjana Carli, A Agresti, Antonella Antonelli, Marco Emilio Bianchi, Eleonora Aronica et al. · 2013 · Neurobiology of Disease
Tumor angiogenesis is enforced by autocrine regulation of high-mobility group box 1
Judy R. Van Beijnum B, Patrycja M. Nowak-Sliwinska, Edith van den Boezem, Petra A. I. Hautvast, Wim A. Buurman, Arjan W. Griffioen · 2012 · Oncogene
Chronic kidney disease worsens sepsis and sepsis-induced acute kidney injury by releasing High Mobility Group Box Protein-1
Asada Leelahavanichkul, Yuning George Huang, Xuzhen Hu, Hua Zhou, Takayuki Tsuji, Richard Chen, Jeffrey B. Kopp, Jurgen B. Schnermann, Peter S.T. Yuen, Robert A. Star · 2011 · Kidney International
Metformin inhibits HMGB1 release in LPS‐treated RAW 264.7 cells and increases survival rate of endotoxaemic mice
Konstantin Tsoyi, Hwa Jin Jang, Irina Tsoy Nizamutdinova, Young Min Kim, Young Soo Lee, Hye Jung Kim, Han Geuk Seo, Jae Heun Lee, Ki Churl Chang · 2010 · British Journal of Pharmacology
Factors masking HMGB1 in human serum and plasma
Vilma Urbonaviciute, Barbara G. Fürnrohr, Christian Weber, Martin Haslbeck, Sabine Wilhelm, Martin Herrmann i, Reinhard Edmund Voll · 2006 · Journal of Leukocyte Biology
Studies of acetylation and deacetylation in high mobility group proteins. Identification of the sites of acetylation in HMG-1.
Richard Sterner, G. Vidali, V. G. Allfrey · 1979 · Journal of Biological Chemistry
Distinct Dendritic Cell Subsets Dictate the Fate Decision between Effector and Memory CD8+ T Cell Differentiation by a CD24-Dependent Mechanism
Taeg S. Kim, Stacey Ann Gorski, Steven Hahn, KENNETH M. M. MURPHY, Thomas J. Braciale · 2014 · Immunity
Chromatin-Specific Remodeling by HMGB1 and Linker Histone H1 Silences Proinflammatory Genes during Endotoxin Tolerance
Mohamed El Gazzar, Barbara K. Yoza, Xiaoping Chen, Benjamin Aaron Garcia, Nicolas L. Young, Charles E. McCall · 2009 · Molecular and Cellular Biology
Multivalent DNA-binding properties of the HMG-1 proteins.
J F Maher, Daniel Nathans · 1996 · Proceedings of the National Academy of Sciences
Receptor for advanced glycation end products and its ligand high-mobility group box-1 mediate allergic airway sensitization and airway inflammation
Md Ashik Ullah, Zhixuan Loh, Wan Jun Gan, Vivian Zhang, Huan Yang, Jian Hua Li, Yasuhiko Yamamoto, Ann Marie Schmidt, Carol Lyn Armour, J. Margaret Hughes et al. · 2014 · Journal of Allergy and Clinical Immunology
Hemorrhagic Shock Activation of NLRP3 Inflammasome in Lung Endothelial Cells
Xiang, Meng, Shi, Xiaolian, Li, Yuehua, Xu, Jia, Yin, Lianhua, Xiao, Guozhi, Scott, Melanie J, Billiar, Timothy R, Wilson, Mark A, Fan, Jie · 2011 · The Journal of Immunology
HMGB proteins and transcriptional regulation
Tetsuya Ueda, Michiteru Yoshida · 2010 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
Proteomic Analysis of Membrane-Associated Proteins from Rat Liver Autophagosomes
Anders Øverbye, Monica Fengsrud Brinchmann, Per O. Seglen · 2007 · Autophagy
Inhibition of Reactive Astrocytes with Fluorocitrate Retards Neurovascular Remodeling and Recovery after Focal Cerebral Ischemia in Mice
Kazuhide Hayakawa, Takafumi Nakano, Keiichi Irie, Sei Higuchi, Masayuki Fujioka, Kensuke Orito, Katsunori Iwasaki, Guang Jin, Eng H. Lo, Kenichi Mishima et al. · 2009 · Journal of Cerebral Blood Flow & Metabolism
High-mobility group box 1 protein plasma concentrations during septic shock
Sébastien Gibot, Frédéric Massin, Aurélie Cravoisy, Damien Barraud, Lionel Nace, B. Levy, Pierre‐Édouard Bollaert · 2007 · Intensive Care Medicine
Transgenic Mice Expressing a Truncated Form of the High Mobility Group I-C Protein Develop Adiposity and an Abnormally High Prevalence of Lipomas
Paola Arlotta, Albert Tai, Guidalberto Manfioletti, Charles B. Clifford, Gilbert Jay, Santa Jeremy Ono · 2000 · Journal of Biological Chemistry
The Receptor for Advanced Glycation End-Products (RAGE) Is Only Present in Mammals, and Belongs to a Family of Cell Adhesion Molecules (CAMs)
Luca Sessa, Elena Gatti, Filippo Zeni, Antonella Antonelli, Alessandro Catucci, Michael Koch, Giulio Pompilio, Günter Fritz, Angela Raucci, Marco Emilio Bianchi · 2014 · PLoS ONE
Autophagy: More Than a Nonselective Pathway
Fulvio Reggiori, Masaaki Komatsu, Kim D. Finley, Anne Simonsen · 2012 · International Journal of Cell Biology
A Cardiovascular Drug Rescues Mice from Lethal Sepsis by Selectively Attenuating a Late-Acting Proinflammatory Mediator, High Mobility Group Box 11
Wei Li, Jian-Hua Li, M. Ashok, Rong-Qian Wu, Dazhi Chen, Li-Hong Yang, Huan Yang, K. Tracey, Ping Wang, A. Sama et al. · 2007 · Journal of Immunology
Increased expression of high mobility group box 1 (HMGB1) is associated with an elevated level of the antiapoptotic c-IAP2 protein in human colon carcinomas
K Volp, M-L Brezniceanu, S Bösser, T Brabletz, T Kirchner, D Göttel, S Joos, M Zörnig · 2005 · Gut
Negative regulation of the Wnt–β‐catenin pathway by the transcriptional repressor HBP1
Ellen M. Sampson, Zaffar K. Haque, Manching Ku, Sergei G. Tevosian, Chris Albanese, Richard G. Pestell, K.Eric Paulson, Amy S. Yee · 2001 · The EMBO Journal
Significant Increase of Serum High-Mobility Group Box Chromosomal Protein 1 Levels in Patients With Severe Acute Pancreatitis
Takeo Yasuda, Takashi Ueda, Yoshifumi Takeyama, Makoto Shinzeki, Hidehiro Sawa, Takahiro Nakajima, Tetsuo Ajiki, Yasuhiro Fujino, Yasuyuki Suzuki, Yoshikazu Kuroda · 2006 · Pancreas
Delayed Treatment With Minocycline Ameliorates Neurologic Impairment Through Activated Microglia Expressing a High-Mobility Group Box1–Inhibiting Mechanism
Kazuhide Hayakawa, Kenichi Mishima, Masanori Nozako, Mai Hazekawa, Shohei Mishima, Masayuki Fujioka, Kensuke Orito, Nobuaki Egashira, Katsunori Iwasaki, Michihiro Fujiwara · 2008 · Stroke
Intranasal Delivery of HMGB1 siRNA Confers Target Gene Knockdown and Robust Neuroprotection in the Postischemic Brain
Il‐Doo Kim, Joo‐Hyun Shin, Seung-Woo Kim, Sunghyun Choi, Junseong Ahn, Pyung‐Lim Han, Jong Sang Park, Ja-Kyeong Lee · 2012 · Molecular Therapy
Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas
Monica Fedele, Francesca Pentimalli, Gustavo Baldassarre et al. · 2005 · Oncogene
HMGB1 is secreted by immunostimulated enterocytes and contributes to cytomix-induced hyperpermeability of Caco-2 monolayers
Shiguang Liu, Donna Beer Stolz, Penny Lynn Sappington, Carlos A. Macias, Meaghan E. Killeen, Jyrki J. Tenhunen, Russell L. Delude, Mitchell P. Fink · 2005 · American Journal of Physiology-Cell Physiology
HMGB-1, A DNA-BINDING PROTEIN WITH CYTOKINE ACTIVITY, INDUCES BRAIN TNF AND IL-6 PRODUCTION, AND MEDIATES ANOREXIA AND TASTE AVERSION
Davide Agnello, Haichao Wang, Huan Yang, Kevin J. Tracey, Pietro Ghezzi · 2002 · Cytokine
High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses
De Yang, Yuri V. Postnikov, Yana Li, Poonam Tewary, Gonzalo de la Rosa, Feng Wei, Dennis M. Klinman, Theresa L. Gioannini, Jerrold P Weiss, Takashi Furusawa et al. · 2011 · The Journal of Experimental Medicine
Extracellular Hmgb1 Functions as an Innate Immune-Mediator Implicated in Murine Cardiac Allograft Acute Rejection
Yun Huang, Hui Yin, Jun-Yan Han, Bo Huang, Juntao Xu, Fang Zheng, Z Tan, M Fang, Li Rui, D Chen et al. · 2007 · American Journal of Transplantation
Clinical Relevance of Circulating Nucleosomes in Cancer
Stefan Holdenrieder, Dorothea Nagel, Andreas Schalhorn et al. · 2008 · Annals of the New York Academy of Sciences
Molecular Signatures of Pancreatic Cancer
Seung‐Mo Hong, Jason Y. Park, Ralph H. Hruban, Michael Goggins · 2011 · Archives of Pathology & Laboratory Medicine
Hepatocyte-Specific High-Mobility Group Box 1 Deletion Worsens the Injury in Liver Ischemia/Reperfusion: A Role for Intracellular High-Mobility Group Box 1 in Cellular Protection
Hai Huang, Gary Nace, Kerry-Ann McDonald, Sheng Tai, John R. Klune, Brian R. Rosborough, Qing Ding, Patricia Loughran, Xiaorong Zhu, Donna Beer–Stolz et al. · 2013 · Hepatology
Efficient Specific DNA Binding by p53 Requires both Its Central and C-Terminal Domains as Revealed by Studies with High-Mobility Group 1 Protein
Kristine M. McKinney, Carol L. Prives · 2002 · Molecular and Cellular Biology
The DNA-bending protein HMGB1 is a cellular cofactor of Sleeping Beauty transposition
Hatem Zayed · 2003 · Nucleic Acids Research
Stoichiometry of Base Excision Repair Proteins Correlates with Increased Somatic CAG Instability in Striatum over Cerebellum in Huntington's Disease Transgenic Mice
Agathi-Vasiliki Goula, Brian R. Berquist, David M. Wilson, Vanessa Chantal Wheeler, Yvon Trottier, Karine Mérienne · 2009 · PLoS Genetics
HMGB1 in vascular diseases: Its role in vascular inflammation and atherosclerosis
Alexandre Wagner Silva de Souza, Johanna Westra, P. C. Limburg, Marc Bijl, Cees G. M. Kallenberg · 2012 · Autoimmunity Reviews
A Major Ingredient of Green Tea Rescues Mice from Lethal Sepsis Partly by Inhibiting HMGB1
Wei Li, Mala Ashok, Jianhua Li, Huan Yang, Andrew E. Sama, Haichao Wang · 2007 · PLoS ONE
Histone Methyltransferase NSD2/MMSET Mediates Constitutive NF-κB Signaling for Cancer Cell Proliferation, Survival, and Tumor Growth via a Feed-Forward Loop
Ping Xun Yang, Linlang Guo, Zhijian Duan, Clifford G. Tepper, Ling Xue, Xinbin Chen, Hsing‐Jien Kung, Allen C. Gao, June X. Zou, Hong-Wu Chen · 2012 · Molecular and Cellular Biology
MicroRNA-10A* and MicroRNA-21 Modulate Endothelial Progenitor Cell Senescence Via Suppressing High-Mobility Group A2
Shoukang Zhu, Shanming Deng, Qi Ma, Taifang Zhang, Chunling Jia, Degen Zhuo, Falin Yang, Jianqin Wei, Liyong Wang, Derek Michael Dykxhoorn et al. · 2012 · Circulation Research
Using Proteomic Approach to Identify Tumor-Associated Proteins as Biomarkers in Human Esophageal Squamous Cell Carcinoma
Jintao Zhang, Kaijuan Wang, 张建中, Samuel S. Liu, Liping Dai, Jian-Ying Zhang · 2011 · Journal of Proteome Research
Interleukin-1 Stimulates β-Cell Necrosis and Release of the Immunological Adjuvant HMGB1
Sarah A. Steer, Anna L. Scarim, Kari T. Chambers, John A. Corbett · 2005 · PLoS Medicine
High-Mobility Group Box Protein 1 Neutralization Reduces Development of Diet-Induced Atherosclerosis in Apolipoprotein E–Deficient Mice
Peter Kanellakis, Alex Agrotis, Tin Soe Kyaw, Christine Koulis, Ingo Ahrens, Shuji Mori, Hideo Kohka Takahashi, Keyue Liu, Karlheinz Peter, Masahiro Nishibori et al. · 2010 · Arteriosclerosis Thrombosis and Vascular Biology
High-mobility group box 1 restores cardiac function after myocardial infarction in transgenic mice
Tatsuro Kitahara, Yasuchika Takeishi, Mutsuo Harada, T. Niizeki, Satoshi Suzuki, Toshiki Sasaki, Mitsunori Ishino, Olga Bilim, Osamu Nakajima, I. Kubota · 2008 · Cardiovascular Research
Neoplastic transformation of rat thyroid cells requires the junB and fra‐1 gene induction which is dependent on the HMGI‐C gene product
Daniela Vallone, Sabrina Battista, Giovanna Maria Pierantoni, Monica Fedele, Laura Casalino, Massimo Mattia Santoro, Giuseppe Viglietto, Alfredo Fusco, Pasquale Verde · 1997 · The EMBO Journal
A Hepatic Protein, Fetuin-A, Occupies a Protective Role in Lethal Systemic Inflammation
Wei Li, Shu Zhu, Jianhua Li, Yan Huang, Zhou Rongrong, Xuegong Fan, Huan Yang, Xing Gong, N. Tony Eissa, Willi Jahnen‐Dechent et al. · 2011 · PLoS ONE
Ghrelin Protects against Experimental Sepsis by Inhibiting High-Mobility Group Box 1 Release and by Killing Bacteria
Alejo Chorny, Per O. Anderson, Elena González‐Rey, Mario Delgado · 2008 · The Journal of Immunology
Interactions of plasminogen and tissue plasminogen activator (t-PA) with amphoterin. Enhancement of t-PA-catalyzed plasminogen activation by amphoterin.
J Parkkinen, Heikki Rauvala · 1991 · Journal of Biological Chemistry
DAMPs and autophagy
Qiuhong Zhang, Rui Kang, Herbert J. Zeh, Michael T. Lotze, Daolin Tang · 2013 · Autophagy
Melatonin protects liver against ischemia and reperfusion injury through inhibition of toll‐like receptor signaling pathway
Jung‐Woo Kang, Eun‐Ji Koh, Sun‐Mee Lee · 2011 · Journal of Pineal Research
High Mobility Group Box 1 (HMGB1) Activates an Autophagic Response to Oxidative Stress
Daolin Tang, Rui Kang, Kristen M. Livesey, Herbert J. Zeh, Michael T. Lotze · 2011 · Antioxidants and Redox Signaling
Targeting HMGB1 in the treatment of sepsis
Haichao Wang, M.F. Ward, Andrew E. Sama · 2014 · Expert Opinion on Therapeutic Targets
Transcriptional Activation of the Cyclin A Gene by the Architectural Transcription Factor HMGA2
Michela A. Tessari, Monica Gostissa, Sandro Altamura, Riccardo Sgarra, Alessandra Rustighi, Clio Salvagno, Giuseppina Caretti, Carol Imbriano, Roberto Mantovani, Giannino Del Sal et al. · 2003 · Molecular and Cellular Biology
High-mobility group box 1 is involved in the initial events of early loss of transplanted islets in mice
N. Matsuoka, Takeshi Itoh, Hiroshi Watarai, Etsuko Sekine-Kondo, Naoki Nagata, Kohji Okamoto, Toshiyuki Mera, Hiroshi Yamamoto, Shingo Yamada, Ikuro Maruyama et al. · 2010 · Journal of Clinical Investigation
HMG‐D, the Drosophila melanogaster homologue of HMG 1 protein, is associated with early embryonic chromatin in the absence of histone H1.
Sarbjit S. Ner, ANDREW A. TRAVERS · 1994 · The EMBO Journal
Differential effects between amphoterin and advanced glycation end products on colon cancer cells
Hiroki Kuniyasu, Yoshitomo Chihara, Hideaki Kondo · 2003 · International Journal of Cancer
HBP1: a HMG box transcriptional repressor that is targeted by the retinoblastoma family.
Sergei G. Tevosian, Heather H. Shih, Karen Mendelson, Kelly-Ann Sheppard, K. Eric Paulson, Amy S. Yee · 1997 · Genes & Development
Competition between histone H1 and HMGN proteins for chromatin binding sites
Frédéric Catez, David T Brown, Tom Misteli · 2002 · EMBO Reports
Architectural elements in nucleoprotein complexes: interchangeability of specific and non‐specific DNA binding proteins.
Anca Mara Segall, Steven D. Goodman, H A Nash · 1994 · The EMBO Journal
Increased expression of the novel proinflammatory cytokine high mobility group box chromosomal protein 1 in skin lesions of patients with lupus erythematosus
Karin Popovic, Monica Ek, Alexander Espinosa, Leonid Padyukov, Helena Erlandsson Harris, Marie Wahren‐Herlenius, Filippa Nyberg · 2005 · Arthritis & Rheumatism
Toll-like receptor 4 regulates early endothelial activation during ischemic acute kidney injury
Jianlin Chen, Reji John, James A. Richardson, John Michael Shelton, Xin Jin Zhou, Yanxia Wang, Qing Wu, John R. Hartono, Pamela D. Winterberg, Christopher Y. Lu · 2010 · Kidney International
Activated protein C inhibits high mobility group box 1 signaling in endothelial cells
Jong‐Sup Bae, Alireza R. Rezaie · 2011 · Blood
HMG2 Interacts with the Nucleosome Assembly Protein SET and Is a Target of the Cytotoxic T-Lymphocyte Protease Granzyme A
Zusen Fan, Paul J. Beresford, Dong Zhang, Judy Lieberman · 2002 · Molecular and Cellular Biology
Antibodies against chromosomal HMG proteins stain the cytoplasm of mammalian cells
Michael Bustin, Natasha K. Neihart · 1979 · Cell
Chromosomal protein HMGN1 enhances the rate of DNA repair in chromatin
Yehudit Birger, Katherine L. West, Yuri V. Postnikov, Jae‐Hwan Lim, Takashi Furusawa, James P. Wagner, Craig S. Laufer, Kenneth H. Kraemer, Michael Bustin · 2003 · The EMBO Journal
Tumor-Derived Autophagosome Vaccine: Mechanism of Cross-Presentation and Therapeutic Efficacy
Yuhuan Li, Lixin Wang, Puiyi Pang, Zhi-Hua Cui, Sandra Aung, Daniel P. Haley, Bernard A. Fox, Walter John Urba, Hong‐Ming Hu · 2011 · Clinical Cancer Research
Increased Susceptibility to LPS-induced Endotoxin Shock in Secretory Leukoprotease Inhibitor (SLPI)-deficient Mice
Akira Nakamura, Yuriko Mori, Koichi Hagiwara, Takuji Suzuki, Tomohiro Sakakibara, Toshiaki Kikuchi, Takayuki Igarashi, Masahito Ebina, Tatsuya Abé, Jun‐ichi Miyazaki et al. · 2003 · The Journal of Experimental Medicine
Evidence for Involvement of HMGB1 Protein in Human DNA Mismatch Repair
Fenghua Yuan, Liya Gu, Shuangli Guo, Chunmei Wang, Guo‐Min Li · 2004 · Journal of Biological Chemistry
High mobility group box protein 1 in complex with lipopolysaccharide or IL-1 promotes an increased inflammatory phenotype in synovial fibroblasts
Heidi Wähämaa, Hanna Schierbeck, Hulda Sigridur Hreggvidsdottir, Karin Palmblad, Ann-Charlotte Aveberger, Ulf Andersson, Helena Erlandsson Harris · 2011 · Arthritis Research & Therapy
DNA looping by the HMG-box domains of HMG1 and modulation of DNA binding by the acidic C-terminal domain
Michal Štros, Jitka Štokrová, Jean Olwen Thomas · 1994 · Nucleic Acids Research
Increased serum HMGB1 level is associated with coronary artery disease in nondiabetic and type 2 diabetic patients
Xiao Xiang Yan, Lin Lu, Wen Hui Peng, Ling Jie Wang, Qi Zhang, Ruiyan Zhang, Qiujing Chen, Wei Feng Shen · 2008 · Atherosclerosis
Soluble RAGE is deficient in neutrophilic asthma and COPD
Maria B. Sukkar, Lisa G. Wood, Melinda Tooze, Jodie Louise Simpson, Vanessa M. McDonald, Peter G. Gibson, Peter A. B. Wark · 2011 · European Respiratory Journal
HMGB1 expression by activated vascular smooth muscle cells in advanced human atherosclerosis plaques
Katsumi Inoue, Koichi Kawahara, Kamal Krishna Biswas, Kenji Ando, Kazuaki Mitsudo, Masakiyo Nobuyoshi, Ikuro Maruyama · 2007 · Cardiovascular Pathology
MIR34Aregulates autophagy and apoptosis by targetingHMGB1in the retinoblastoma cell
Ke Liu, Jun Xing Huang, Min Xie, Yan Hui Yu, Shan Zhu, Rui Kang, Lizhi Cao, Daolin Tang, Xuanchu Duan · 2014 · Autophagy
The expression of HMGB1 protein and its receptor RAGE in human malignant tumors
Nora N. Kostova, Stanislava Zlateva, Iva Ugrinova, Evdokia Alexandrova Pasheva · 2009 · Molecular and Cellular Biochemistry
RAGE and the pathogenesis of chronic kidney disease
Vivette Denise D’Agati, Ann Marie Schmidt · 2010 · Nature Reviews Nephrology
The Anti-inflammatory Effects of Heat Shock Protein 72 Involve Inhibition of High-Mobility-Group Box 1 Release and Proinflammatory Function in Macrophages
Daolin Tang, Rui Kang, Weimin Xiao, Haichao Wang, Stuart K. Calderwood, Xianzhong Xiao · 2007 · The Journal of Immunology
HMGA and Cancer
Monica Fedele, Alfredo Fusco · 2010 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
Blockade of high mobility group box-1 protein attenuates experimental severe acute pancreatitis
Hidehiro Sawa · 2006 · World Journal of Gastroenterology
HMGA2 Participates in Transformation in Human Lung Cancer
Francescopaolo Di Cello, Jöelle Hillion, Alexandra C. Hristov, Lisa J. Wood, Mita Mukherjee, Andrew Schuldenfrei, Jeanne Kowalski, Raka Bhattacharya, Raheela Ashfaq, Linda M S Resar · 2008 · Molecular Cancer Research
Selective Proinflammatory Activation of Astrocytes by High-Mobility Group Box 1 Protein Signaling
Marco Pedrazzi, Mauro Patrone, Mario Passalacqua, Elia Ranzato, Diego Colamassaro, Bianca Sparatore, S. Pontremoli, Edon Melloni · 2007 · The Journal of Immunology
Anti-inflammatory effects of rutin on HMGB1-induced inflammatory responses in vitro and in vivo
Hayoung Yoo, Sae‐Kwang Ku, Young-Doo Baek, Jong‐Sup Bae · 2013 · Inflammation Research
HMGB1-Facilitated p53 DNA Binding Occurs via HMG-Box/p53 Transactivation Domain Interaction, Regulated by the Acidic Tail
John P. Rowell, Kathryn Simpson, Katherine M. Stott, Matthew Lamont Watson, Jean Olwen Thomas · 2012 · Structure
Caveolin-1 Increases Aerobic Glycolysis in Colorectal Cancers by Stimulating HMGA1-Mediated GLUT3 Transcription
Tae-Kyu Ha, Nam-Gu Her, Min Goo Lee, Byung–Kyu Ryu, Jinhee Lee, Jikhyon Han, Seong-In Jeong, Min Ju Kang, Nam-Hoon Kim, Hyo-Jong Kim et al. · 2012 · Cancer Research
Neuroprotection by biodegradable PAMAM ester (e-PAM-R)-mediated HMGB1 siRNA delivery in primary cortical cultures and in the postischemic brain
Il‐Doo Kim, Chaemoon Lim, Jung‐Bin Kim, Hye Yeong Nam, Kihoon Nam, Seung-Woo Kim, Jong‐Sang Park, Ja-Kyeong Lee · 2009 · Journal of Controlled Release
HMGB1 inhibitor glycyrrhizin attenuates intracerebral hemorrhage-induced injury in rats
Masatoshi Ohnishi, Hiroshi Katsuki, Chiharu Fukutomi, Madoka Takahashi, Misato Motomura, Mizuki Fukunaga, Yasuhiro Matsuoka, Yoichiro Isohama, Yasuhiko Izumi, Toshiaki Kume et al. · 2011 · Neuropharmacology
The TLR4 antagonist CRX-526 protects against advanced diabetic nephropathy
Miao Yu Lin, Wai Han Yiu, Rui Xi Li, Hao Wu, Dickson W.L. Wong, Loretta Y.Y. Chan, Joseph C.K. Leung, Kar Neng Lai, Sydney C.W. Tang · 2013 · Kidney International
HMGA1 and HMGA2 protein expression in mouse spermatogenesis
Paolo Chieffi, Sabrina Battista, Marco Barchi · 2002 · Oncogene
BAF57 Governs Androgen Receptor Action and Androgen-Dependent Proliferation through SWI/SNF
Kevin A. Link, Craig J. Burd, Erin Williams, Thomas W. Marshall, Gary B. Rosson, Erin C. Henry, Bernard E. Weissman, Karen E. Knudsen · 2005 · Molecular and Cellular Biology
Emerging Role of High-Mobility Group Box 1 (HMGB1) in Liver Diseases
Ruochan Chen, Wen Hou, Qiuhong Zhang, Rui Kang, Xuegong Fan, Daolin Tang · 2013 · Molecular Medicine
Phosphorylation by cdc2 kinase modulates DNA binding activity of high mobility group I nonhistone chromatin protein.
Mark S. Nissen, Thomas A. Langan, Raymond Reeves · 1991 · Journal of Biological Chemistry
Extracellular high mobility group box chromosomal protein 1 is a coupling factor for hypoxia and inflammation in arthritis
Takashi Hamada, Motofumi Torikai, Ai Kuwazuru, Motoyuki Tanaka, Naoto Horai, Takeshi Fukuda, Shingo Yamada, Shinichi Nagayama, Kanehisa Hashiguchi, Nobuhiko Sunahara et al. · 2008 · Arthritis & Rheumatism
Structure of a Complex of Tandem HMG Boxes and DNA
Katherine M. Stott, George S.F. Tang, Keng‐Boon Lee, Jean Olwen Thomas · 2006 · Journal of Molecular Biology
N‐Glycans on the receptor for advanced glycation end products influence amphoterin binding and neurite outgrowth
Geetha Srikrishna, Henri J. Huttunen, Lena Johansson, Bernd Weigle, Yu Yamaguchi, Heikki Rauvala, Hudson H. Freeze · 2002 · Journal of Neurochemistry
The cell biology of regeneration
Ryan S. King, Phillip A. Newmark · 2012 · The Journal of Cell Biology
Truncated and chimeric HMGI-C genes induce neoplastic transformation of NIH3T3 murine fibroblasts
Monica Fedele, Maria Teresa Berlingieri, Stefania Scala · 1998 · Oncogene
Transplantation of umbilical cord mesenchymal stem cells alleviates lupus nephritis in MRL/lpr mice
Zhifeng Gu, Kentaro Akiyama, Xiaolei Ma, Hao Zhang, Xuebing Feng, Genhong Yao, Yuchuan Hou, Liwei Lu, GS Gilkeson, Robert M. Silver et al. · 2010 · Lupus
Induction of high mobility group box-1 in dorsal root ganglion contributes to pain hypersensitivity after peripheral nerve injury
Masayuki Shibasaki, Mika Sasaki, Mayumi Miura, Keiko Mizukoshi, Hiroshi Ueno, Satoru Hashimoto, Yoshifumi Tanaka, Fumimasa Amaya · 2010 · Pain
A Functional Screen to Identify Novel Effectors of Hematopoietic Stem Cell Activity
Éric Deneault, Sonia Cellot, Amélie Faubert, Jean‐Philippe Laverdure, Mélanie Fréchette, Jalila Chagraoui, Nadine Mayotte, Martin Sauvageau, Stephen B. Ting, Guy Sauvageau · 2009 · Cell
NAC1 modulates sensitivity of ovarian cancer cells to cisplatin by altering the HMGB1-mediated autophagic response
Yi Zhang, Yan Cheng, Xingcong Ren, Lijuan Zhang, Kai Lee Yap, H Wu, R Patel, D Liu, Z-H Qin, Ie‐Ming Shih et al. · 2011 · Oncogene
HMGB1 inhibits macrophage activity in efferocytosis through binding to the αvβ3-integrin
Arnaud Friggeri, Yanping Yang, Sami Banerjee, Yong-Jun Park, Gang Liu, Edward H Abraham · 2010 · American Journal of Physiology-Cell Physiology
Tissue specificity of nucleo‐cytoplasmic distribution of HMG1 and HMG2 proteins and their probable functions
Mark I. Mosevitsky, Vera Novitskaya, Iogannsen Mg, Mark A. Zabezhinsky · 1989 · European Journal of Biochemistry
Differential association of HMG1 and linker histones B4 and H1 with dinucleosomal DNA: structural transitions and transcriptional repression.
K. Ura, Karl P. Nightingale, Alan P. Wolffe · 1996 · The EMBO Journal
The role of HMGB1 in the pathogenesis of rheumatic disease
Ulf Andersson, Helena Erlandsson Harris · 2010 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
HMGB1: Roles in base excision repair and related function
Yuan Liu, Rajendra Prasad, Samuel H. Wilson · 2010 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
High Mobility Group Box I (HMGB1) Release From Tumor Cells After Treatment: Implications for Development of Targeted Chemoimmunotherapy
Xiang Da Dong, Norimasa Ito, Michael T. Lotze, Richard DeMarco, P. Popovič, Stuart H. Shand, Simon C. Watkins, Stephen E. Winikoff, Charles K. Brown, David L. Bartlett et al. · 2007 · Journal of Immunotherapy
High mobility group proteins 1 and 2 function as general class II transcription factors
Jagmohan Singh, Gordon H. Dixon · 1990 · Biochemistry
MicroRNA-137, an HMGA1 Target, Suppresses Colorectal Cancer Cell Invasion and Metastasis in Mice by Directly Targeting FMNL2
Liang Li, Xianzheng Li, Xiaojing Zhang, Zhenbing Lv, Guoyang He, Wei Zhao, Xiaoli Ren, Yuling Li, Xiuwu Bian, Wenting Liao et al. · 2012 · Gastroenterology
NOVEL HMGB1-INHIBITING THERAPEUTIC AGENTS FOR EXPERIMENTAL SEPSIS
Haichao Wang, M.F. Ward, Andrew E. Sama · 2009 · Shock
Metabolic regulation by HMGB1-mediated autophagy and mitophagy
Rui Kang, Kristen M. Livesey, Herbert J. Zeh, Michael T. Loze, Daolin Tang · 2011 · Autophagy
Amphoterin Stimulates Myogenesis and Counteracts the Antimyogenic Factors Basic Fibroblast Growth Factor and S100B via RAGE Binding
Guglielmo Sorci, Francesca Riuzzi, Cataldo Arcuri, Ileana Giambanco, Rosario Donato · 2004 · Molecular and Cellular Biology
Expression of receptor for advanced glycation end products and HMGB1/amphoterin in colorectal adenomas
Tomonori Sasahira, Yoshihiko Akama, Kiyomu Fujii, Hiroki Kuniyasu · 2005 · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
High Mobility Group 1 Protein Is Not Stably Associated with the Chromosomes of Somatic Cells
Luca Falciola, Fabio Spada, Sabina Calogero, Gernot Längst, Renate Voit, Ingrid Grummt, Marco Emilio Bianchi · 1997 · The Journal of Cell Biology
Mast Cell Chymase Degrades the Alarmins Heat Shock Protein 70, Biglycan, HMGB1, and Interleukin-33 (IL-33) and Limits Danger-induced Inflammation
Ananya Roy, Goutham Ganesh, Helena Sippola, Sara Bolin, Osama Sawesi, Anders Dagälv, Susan Schlenner, Thorsten B. Feyerabend, Hans-Reimer Rodewald, Lena Kjellén et al. · 2013 · Journal of Biological Chemistry
Requirement of HMGB1 for stromal cell–derived factor–1/CXCL12–dependent migration of macrophages and dendritic cells
Lara Campana, Lidia Bosurgi, Marco Emilio Bianchi, Angelo Andrea Manfredi, Patrizia Querini Rovere · 2009 · Journal of Leukocyte Biology
High Mobility Group Protein Bl (HMGB1) in Asthma: Comparison of Patients with Chronic Obstructive Pulmonary Disease and Healthy Controls
Changchun Hou, Haijin Zhao, Laiyu Liu, Wenjun Li, Xiaoting Zhou, Yanhua Lv, Xiang-bo Shen, Zhenyu Liang, Shaoxi Cai, Fei Zou · 2011 · Molecular Medicine
Quercetin Prevents LPS-Induced High-Mobility Group Box 1 Release and Proinflammatory Function
Daolin Tang, Rui Kang, Weimin Xiao, Huali Zhang, Michael T. Lotze, Haichao Wang, Xianzhong Xiao · 2009 · American Journal of Respiratory Cell and Molecular Biology
Toll-like receptor regulation of intestinal development and inflammation in the pathogenesis of necrotizing enterocolitis
Peng Lü, Chhinder P. Sodhi, David Joel Hackam · 2013 · Pathophysiology
Hmgb3 regulates the balance between hematopoietic stem cell self-renewal and differentiation
Michael J. Nemeth, Martha Kirby, David M. Bodine · 2006 · Proceedings of the National Academy of Sciences
Suppression of HMGB1 release by stearoyl lysophosphatidylcholine:an additional mechanism for its therapeutic effects in experimental sepsis
Guoqian Chen, Jianhua Li, Xiaoling Qiang, Christopher J. Czura, Mahendar Ochani, Kanta Ochani, Luis Ulloa, Huan Yang, Kevin J. Tracey, Ping Wang et al. · 2005 · Journal of Lipid Research
Heme oxygenase-1 mediates the anti-inflammatory effect of molecular hydrogen in LPS-stimulated RAW 264.7 macrophages
Hongguang Chen, Keliang Xie, Huan-zhi Han, Weina Wang, Da-Quan Liu, Guolin Wang, Yonghao Yu · 2013 · International Journal of Surgery
Identification of two forms of the RNA polymerase I transcription factor UBF.
Daniel J. O’Mahony, Lawrence Ian Rothblum · 1991 · Proceedings of the National Academy of Sciences
Serum high mobility group box-1 (HMGB1) is closely associated with the clinical and pathologic features of gastric cancer
Hye Won Chung, Sang‐Guk Lee, Heejung Kim, Duck Jin Hong, Jae Bock Chung, David Stroncek, Jong‐Baeck Lim · 2009 · Journal of Translational Medicine
Fucoidan, a sulfated polysaccharide from brown algae, against myocardial ischemia-reperfusion injury in rats via regulating the inflammation response.
Chun-Mei Li, Yong-Lin Gao, Y. Xing, Hai-Bo Zhu, Jing-Yu Shen, Jing-Wei Tian · 2011 · Food and Chemical Toxicology
High-Mobility Group Box-1 Protein Promotes Angiogenesis After Peripheral Ischemia in Diabetic Mice Through a VEGF-Dependent Mechanism
Federico Biscetti, Giuseppe Straface, Raimondo DE CRISTOFARO, Stefano Lancellotti, Paola Rizzo, Vincenzo Arena, Egidio Stigliano, Giovanni Pecorini, Kensuke Egashira, Giulia De Angelis et al. · 2010 · Diabetes
Essential role of monocytes and macrophages in the progression of acute pancreatitis
Pratima Shrivastava · 2010 · World Journal of Gastroenterology
Role of HMGB1 in cardiovascular diseases
Wei Li, A. Sama, Haichao Wang · 2006 · Current Opinion in Pharmacology
Intra- and Intermolecular Cooperative Binding of High-Mobility-Group Protein I(Y) to the Beta-Interferon Promoter
Junming Yie, Stanley Liang, Menie Merika, Dimitris Thanos · 1997 · Molecular and Cellular Biology
Gene Silencing of NALP3 Protects Against Liver Ischemia–Reperfusion Injury in Mice
Ping Zhu, Lihua Duan, Jie Chen, Ali Xiong, Qin Lan Xu, Hongwei Zhang, Fang Zheng, Zheng Tan, Feili Gong, Min Fang · 2010 · Human Gene Therapy
Cellular-specific role of toll-like receptor 4 in hepatic ischemia-reperfusion injury in mice
Gary Nace, Hai Huang, John R. Klune et al. · 2013 · Hepatology
Calcium/Calmodulin-Dependent Protein Kinase (CaMK) IV Mediates Nucleocytoplasmic Shuttling and Release of HMGB1 during Lipopolysaccharide Stimulation of Macrophages
Xianghong Zhang, David Wheeler, Ying Margie Tang, Lanping Guo, Richard A. Shapiro, Thomas J. Ribar, Anthony R. Means, Timothy R. Billiar, Derek C. Angus, Matthew Randall Rosengart · 2008 · The Journal of Immunology
Polyphosphate amplifies proinflammatory responses of nuclear proteins through interaction with receptor for advanced glycation end products and P2Y1 purinergic receptor
Peyman Dinarvand, Seyed Mahdi Hassanian, Shabir Hussain Qureshi, Chandrashekhara Manithody, Joel C. Eissenberg, Likui Yang, Alireza R. Rezaie · 2013 · Blood
Programmed Cellular Necrosis Mediated by the Pore-Forming α-Toxin from Clostridium septicum
Catherine L. Kennedy, Danielle J. Smith, Dena Lyras, Anjana Chakravorty, Julian I. Rood · 2009 · PLoS Pathogens
Potential Role of High-Mobility Group Box 1 in Cystic Fibrosis Airway Disease
Steven Mark Rowe, Patricia L. Jackson, Gang Liu, Mathew Hardison, Alessandra Livraghi-Butrico, George Martin Solomon, D. Brent McQuaid, Brett D. Noerager, Amit Gaggar, John Paul Clancy et al. · 2008 · American Journal of Respiratory and Critical Care Medicine
The Role of Toll-Like Receptor 2 in Inflammation and Fibrosis during Progressive Renal Injury
Jaklien C. Leemans, Loes M. Butter, Wilco P. C. Pulskens, Gwendoline J. D. Teske, Nike Claessen, Tom van der Poll, Sandrine Florquin · 2009 · PLoS ONE
Increasing numbers of hepatic dendritic cells promote HMGB1-mediated ischemia-reperfusion injury
Allan Tsung, Ning Zheng, Geetha Jeyabalan, Kunihiko Izuishi, John R. Klune, David A. Geller, Michael T. Lotze, Lina Lü, Timothy R. Billiar · 2006 · Journal of Leukocyte Biology
The redox protein HMGB1 regulates cell death and survival in cancer treatment
Daolin Tang, Michael T. Loze, Herbert J. Zeh, Rui Kang · 2010 · Autophagy
The RAG1 Homeodomain Recruits HMG1 and HMG2 To Facilitate Recombination Signal Sequence Binding and To Enhance the Intrinsic DNA-Bending Activity of RAG1-RAG2
Vassilis Aidinis, Tiziana Bonaldi, Mônica Beltrame, Sandro Santagata, Marco Emilio Bianchi, Eugenia Spanopoulou · 1999 · Molecular and Cellular Biology
Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach
Mark N. Lee, Matthew Roy, Shao‐En Ong, Philipp Mertins, Alexandra–Chloé Villani, Weibo Li, Farokh Dotiwala, Jayita Sen, John G. Doench, Megan H. Orzalli et al. · 2012 · Nature Immunology
Cutting Edge: High-Mobility Group Box 1 Preconditioning Protects against Liver Ischemia-Reperfusion Injury
Izuishi, Kunihiko, Tsung, Allan, Jeyabalan, Geetha, Critchlow, Nathan D, Li, Jianhua, Tracey, Kevin J, Demarco, Richard A, Lotze, Michael T, Fink, Mitchell P, Geller, David A et al. · 2006 · The Journal of Immunology