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Direct-to-Consumer Testing 2.0: Emerging Models of Direct-to-Consumer Genetic Testing

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Allyse, Megan A., Robinson, David H., Ferber, Matthew J., Sharp, Richard R.·2018·Mayo Clinic Proceedings

DOI 10.1016/j.mayocp.2017.11.001

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Abstract

Direct-to-consumer (DTC) genetic testing emerged in the early 2000s as a means of allowing consumers to access information on their genetics without the involvement of a physician. Although early models of DTC were popular with consumers, they were controversial in medical and regulatory circles. In this article, we trace the history of DTC genetic testing, discuss its regulatory implications, and describe the emergence of a new hybrid model we call DTC 2.0.

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Authors: Allyse, M. A., Robinson, D. H., Ferber, M. J., & Sharp, R. R.
Affiliations: Mayo Clinic (US)
Corresponding author: Sharp, Richard R.
ORCID: Allyse, Megan A.
Robinson, David H.
Ferber, Matthew J.
Sharp, Richard R.
Venue: Mayo Clinic Proceedings
Publisher: Elsevier BV
Published: 2018-01
Volume: 93
Issue: 1
Pages: 113-120
ISSN: 0025-6196 (ISSN-L)
DOI: 10.1016/j.mayocp.2017.11.001
OpenAlex: W2781996111
Cited by: 139
References: 20
Citations by year: 2026: 3 · 2025: 13 · 2024: 16 · 2023: 10 · 2022: 18 · 2021: 22 · 2020: 31 · 2019: 18 · 2018: 8
FWCI: 13.63
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Mayo Clinic Proceedings (publishedVersion)
PubMed (publishedVersion)
Funders: Center for Individualized Medicine, Mayo Clinic
Topics: Health Sciences › Nursing › Issues, ethics and legal aspects › Biomedical Ethics and Regulation
Social Sciences › Law › Medical and Health Sciences Research
Social Sciences › Anthropology › Race, Genetics, and Society
Keywords: direct-to-consumer genetic testing, genetic testing regulation, hybrid business models, genetic counseling
MeSH terms: Direct-To-Consumer Screening and Testing, Computer-Assisted Instruction, Curriculum, Education, Medical, Continuing, Genetic Testing, Humans, Minnesota, History, 21st Century

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Direct-to-Consumer Testing 2.0: Emerging Models of Direct-to-Consumer Genetic Testing

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