Cited by 48Receptor Mechanisms and SignalingDevelopmental Biology and Gene RegulationNeuropeptides and Animal Physiology

The evolution of the ligand/receptor couple: a long road from comparative endocrinology to comparative genomics

Open access
Markov, Gabriel V., Paris, Mathilde, Bertrand, Stéphanie, Laudet, Vincent·2008·Molecular and Cellular Endocrinology

Abstract

Comparative endocrinology considers the evolution of bioregulatory systems and the anatomical structures and molecules that constitute the neuroendocrine and endocrine systems. One aim of comparative endocrinology is to trace the origins of the main endocrine systems. The understanding of the evolution of the ligand/receptor couple is central to this objective. One classical approach to tackle this question is the characterization of receptors and ligands in various types of non-model organisms using as a starting point the knowledge accumulated on classical models such as mammals (mainly human and mouse) and arthropods (with Drosophila among other insects). In this review we discuss the potential caveats associated to this two-by-two comparison between a classical model and non-model organisms. We suggest that the use of an evolutionary approach involving comparisons of several organisms in a coherent framework permits reconstruction of the most probable scenarios. The use of the vast amount of genomic data now available, coupled to functional experiments, offers unprecedented possibilities to trace back the origins of the main ligand/receptor couples.

Integrity signals

Registry

Crossref · 10.1016/j.mce.2008.06.011

Cites

107 of 107 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Studying the OT/AVP nonapeptide family and the corresponding structure of their cognate receptors serves as an interesting test case in ligand-receptor coevolution, given the long evolutionary history of these peptide systems (~600 million years) and evolutionary changes in ligand structure.

    “Studying the OT/AVP nonapeptide family and the corresponding structure of their cognate receptors serves as an interesting test case in ligand-receptor coevolution (Markov et al., 2008), given the long evolutionary history of these peptide systems (~600 million years) and evolutionary changes in ligand structure.”

    From Neuropeptide diversity and the regulation of social behavior in New World primates (2016) · cites this paper as Markov et al., 2008

Cites

Flagged first, then by citations

1 of the 108 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Authors
Markov, G. V., Paris, M., Bertrand, S., & Laudet, V.
Affiliations
  • Lyon 1 Université (FR)
  • Universitat de Barcelona (ES)
Corresponding author
Laudet, Vincent
Venue
Molecular and Cellular Endocrinology
Publisher
Elsevier BV
Published
2008-10
Volume
293
Issue
1-2
Pages
5-16
ISSN
0303-7207 (ISSN-L)
OpenAlex
W2015979867
Cited by
48
References
108
Citations by year
2024: 1 · 2022: 2 · 2021: 4 · 2020: 5 · 2019: 2 · 2018: 1 · 2017: 4 · 2016: 3 · 2014: 4 · 2013: 1 · 2012: 1
FWCI
0.51
Type
journal article
Language
en
Open access
Locations
  • Molecular and Cellular Endocrinology (publishedVersion)
  • PubMed (publishedVersion)
  • HAL (submittedVersion, other-oa)
  • Trinity's Access to Research Output (TARA) (Trinity College Dublin) (submittedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
Keywords
comparative endocrinology, comparative genomics, neuroendocrine system, receptor evolution, non-model organisms, model organisms, Drosophila, arthropods
MeSH terms
Animals, Drosophila, Endocrine System, Humans, Ligands, Phylogeny, Recombination, Genetic, Caenorhabditis elegans, Gene Deletion, Receptors, Cytoplasmic and Nuclear, Evolution, Molecular, Gene Duplication, Genomics

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review