Mitochondrial signals drive insulin secretion in the pancreatic β-cell

Wiederkehr, Andreas, Wollheim, Claes B.·2012·Molecular and Cellular Endocrinology

Cited by (133)

Items 101–133 of 133

  1. Drp1 Overexpression Decreases Insulin Content in Pancreatic MIN6 Cells
    Uma Dhiraj Kabra, Noah Moruzzi, Per‐Olof Berggren, Martin Jastroch · 2022 · International Journal of Molecular Sciences
  2. Pancreatic β-cells respond to fuel pressure with an early metabolic switch
    Ronja M. Malinowski, Seyed Mojtaba Ghiasi, Thomas R Mandrup-Poulsen, Sebastián Meier, Mathilde H. Lerche, Jan Henrik Ardenkjær‐Larsen, Pernille Rose Jensen · 2020 · Scientific Reports
  3. Protein Lysine Acetylation: Grease or Sand in the Gears of β-Cell Mitochondria?
    Jaime Santo Domingo, Loı̈c Dayon, Andreas Wiederkehr · 2019 · Journal of Molecular Biology
  4. Glycogen metabolism in the glucose‐sensing and supply‐driven β‐cell
    Lotta E. Andersson, Lisa M. Nicholas, Karin Filipsson, Jiangming Sun, Anya Medina, Mahmoud Al‐Majdoub, Malin Fex, Hindrik Mulder, Peter Spégel · 2016 · FEBS Letters
  5. Black seed oil reverses chronic antibiotic-mediated depression and social behaviour deficits via modulation of hypothalamic mitochondrial-dependent markers and insulin expression
    Mujeeb Adekunle Adedokun, Linus Anderson Enye, Elizabeth Toyin Akinluyi, Toheeb Adesumbo Ajibola, Edem Ekpenyong Edem · 2024 · IBRO Neuroscience Reports
  6. Encapsulation of Insulin‐Secreting Cells Expressing a Genetically Encoded Fluorescent Calcium Indicator for Cell‐Based Sensing In Vivo
    Christophe Boss A, Umberto De Marchi, Aurélie Hermant, Mouna Conrad, Federico Sizzano, Alessio G. Palini, Andreas Wiederkehr, Nicolas Bouche · 2016 · Advanced Healthcare Materials
  7. The NERP-4–SNAT2 axis regulates pancreatic β-cell maintenance and function
    Weidong Zhang, Ayako Miura, Md Moin Abu Saleh, Koichiro Shimizu, Yuichiro Mita, Ryota Tanida, Satoshi Hirako, Seiji Shioda, Valéry Gmyr, Julie A. Kerr-Conte et al. · 2023 · Nature Communications
  8. Antibiotics induce mitonuclear protein imbalance but fail to inhibit respiration and nutrient activation in pancreatic β-cells
    Jaime Santo Domingo, Isabelle Chareyron, Charlotte Broenimann, Steve Lassueur, Andreas Wiederkehr · 2017 · Experimental Cell Research
  9. Cellular stress is a prerequisite for glucose-induced mitochondrial matrix alkalinization in pancreatic β-cells
    Isabelle Chareyron, Christopher T. Wall, Jonathan Thévenet, Jaime Santo Domingo, Andreas Wiederkehr · 2018 · Molecular and Cellular Endocrinology
  10. Metabolism–Secretion Coupling and Mitochondrial Calcium Activities in Clonal Pancreatic β-Cells
    Lukas N. Groschner, Muhammad Rizwan Alam, Wolfgang F. Graier · 2014 · Vitamins and hormones
  11. Conversion of glutamate into proline by the leucine analog BCH enhances biphasic insulin secretion in pancreatic β-cells
    Sevda Gheibi, Luis Rodrigo Cataldo, Hamidreza Ardalani, Lisa Nocquet, Peter Spégel, Susanne G. Straub, Geoffrey W.G. Sharp, Malin Fex, Hindrik Mulder · 2025 · Journal of Biological Chemistry
  12. Activation of imidazoline receptor I 2 , and improved pancreatic β-cell function in human islets
    Stefan Amisten, Pontus Dunér, Olof Asplund, Israa Mohammed Al-Amily, Leif Groop, Albert A. Salehi · 2018 · Journal of Diabetes and its Complications
  13. Nutritional Composition and Anti-Type 2 Diabetes Mellitus Potential of Femur Bone Extracts from Bovine, Chicken, Sheep, and Goat: Phytochemical and In Vivo Studies
    Naseh A. Algehainy, Esraa M. Mohamed, Hanan Farouk Aly, Eman A. Younis, Faisal H. Altemani, Mohammad A. Alanazi, Gerhard Bringmann, Usama Ramadan Abdelmohsen, Abeer H. Elmaidomy · 2023 · Nutrients
  14. MELAS, MIDD and Beyond: m.3243A>G MT-TL1 Mutation in Adult Patients
    Bun Sheng, Man Kei Fong, Wing Kwan Ng, Sammy Pak Lam Chen, Chloe Miu Mak · 2016 · International Journal of Clinical Medicine
  15. Perturbed Mitochondrial Metabolism in Islets from Donors with Type-2 Diabetes
    Jiangming Sun, Ruchi Jain, Lotta E. Andersson, Anya Medina, Petter Storm, Peter Spégel, Hindrik Mulder · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
  16. Mitochondrial diabetes in mice expressing a dominant-negative allele of nuclear respiratory factor-1 ( Nrf1 ) in pancreatic β-cells
    Fionnuala M. Morrish, Hélène Gingras, Joanna Noonan, Li Huang, Ian R. Sweet, Iok Teng Kuok, Sue E. Knoblaugh, David M. Hockenbery · 2023 · Biochemical and Biophysical Research Communications
  17. Factors Influencing Mitochondrial Function as a Key Mediator of Glucose-Induced Insulin Release: Highlighting Nicotinamide Nucleotide Transhydrogenase.
    Zahra Aghelan, Sara Kiani, Abolfazl Nasiri, Masoud Sadeghi, Alireza Farrokhi, Reza Khodarahmi‬ · 2020 · PubMed Central
  18. Targeting Mitochondrial Ion Channels in Type 2 Diabetes
    Andreas Wiederkehr, Jaime Santo Domingo · 2020 · Future Medicinal Chemistry
  19. Altered mitochondrial functionality in metabolic disorders: insights from Drosophila studies
    Yunlin Zeng, Yang Yang, Yuao Zhu, Peixin Xu, Chakin Cheong, Yong Juan Zhao, Gyeong Hun Baeg · 2026 · Frontiers in Endocrinology
  20. SLC25A46 promotes mitochondrial fission and mediates resistance to lipotoxic stress in INS-1E insulin-secreting cells
    Jaime Santo Domingo, Steve Lassueur, Antonio Núñez Galindo, Pilar Álvarez-Illera, Silvia Romero-Sanz, Elena Caldero-Escudero, Sergio de la Fuente, Loı̈c Dayon, Andreas Wiederkehr · 2023 · Journal of Cell Science
  21. A practical and robust method to evaluate metabolic fluxes in primary pancreatic islets
    Débora Santos Rocha, Antonio Carlos Manucci, Alexandre Bruni‐Cardoso, Alicia Juliana Kowaltowski, Eloisa Aparecida Vilas‐Boas · 2024 · Molecular Metabolism
  22. Biosynthesis, Processing, and Secretion of the Islet Hormones
    Donald F. Steiner, Christopher J. Rhodes, Louis H. Philipson, Graeme I. Bell, Shu Jin Chan · 2015 · Elsevier eBooks
  23. Contributions of Mitochondrial Dysfunction to β Cell Failure in Diabetes Mellitus
    Julia Parnis, Guy A. Rutter · 2019 · Elsevier eBooks
  24. Disruption of perinatal myeloid niches impacts the aging clock of pancreatic β cells
    Jessica O'Sell, Vincenzo Cirulli, Stephanie Pardike, Marie Aare Bentsen, Patima Sdek, Jasmine Anderson, Dale W. Hailey, Mary C. Regier, Sina A. Gharib, Laura Crisá · 2024 · iScience
  25. Exploring the Fundamentals of Platelet Granular Storage and Secretion at the Single
    Secil Koseoglu · 2013
  26. Physiological functions of mitochondrial ion transport in insulin-releasing cells
    권향란 · 2014
  27. Cystathionine gamma-lyase/hydrogen sulfide system and glucose homeostasis
    Ling Zhang · 2013 · Knowledge Commons (Lakehead University)
  28. Mitochondrial and insulin gene expression in single cells shape pancreatic beta cells’ population divergence
    Hadar Medini, Tal Cohen, Dan Mishmar · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  29. Mitochondrien als Kraftwerk der β-Zelle
    Simone Baltrusch, F. Reinhardt, Markus Tiedge · 2015 · Der Diabetologe
  30. A practical and robust method to evaluate metabolic fluxes in pancreatic islets
    Débora Santos Rocha, Antonio Carlos Manucci, Alexandre Bruni‐Cardoso, Alicia Juliana Kowaltowski, Eloisa Aparecida Vilas‐Boas · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  31. Addressing bioenergetic deficits and restoring mitochondrial health in transplanted islets using mesenchymal stem cells
    Rosita Primavera, Abantika Ganguly, Reza Yarani, Lili Bettencourt, Shobha Regmi, Shashank Shankar Chetty, Jing Wang, Michele Guindani, Ramasamy Paulmurugan, Avnesh Sinh Thakor · 2026 · Stem Cells Translational Medicine
  32. In vivo dysregulation of insulin and glucagon secretion: Disturbed mitochonderial VDAC1 expression and localization in pancreatic β-cells convey global insulin secretory defects in diabetic GK rat
    Albert A. Salehi, Israa Mohammed Al-Amily, Fariborz Parandeh, Claes‐Göran Östenson, Ingmar Lundquist · 2026 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  33. Miro1 mediates skeletal muscle insulin resistance in type 2 diabetes
    Elizabeth C. Heintz, Wagner S. Dantas, Analisa L. Taylor, Elizabeth R. M. Zunica, Kathryn P. Belmont, Jackson M. Slone, Jacob T. Mey, Robbie A. Beyl, Bolormaa Vandanmagsar, Hailey A. Parry et al. · 2026 · Nature Communications