The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Androgen action and metabolism in prostate cancer
Open accessAbstract
The transcriptional programs regulated through the activity of the androgen receptor (AR) modulate normal prostate development and the maintenance of prostatic functions at maturity. AR signaling also controls key survival and growth functions operative in prostate cancer. Inhibiting the AR program remains the key target in the treatment of advanced prostate cancer, and suppressing AR also holds great potential for preventing the development or progression of early stage prostate cancer. In this review, we detail molecular mechanisms of AR activity, cellular components contributing to the maintenance of AR signaling despite AR-ligand suppression, and discuss treatment strategies designed to target components of resistance to AR-directed therapeutics.
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Cites
Abiraterone and Increased Survival in Metastatic Prostate Cancer
de Bono, J. S., Logothetis, C. J., Molina, A., Fizazi, K., North, S., Chu, L., Chi, K. N., Jones, R. J., Goodman, O. B., Saad, F., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1014618 · Cited by 4,407
The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity
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Molecular determinants of resistance to antiandrogen therapy
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Androgen Receptor in Prostate Cancer
Heinlein, C. A., & Chang, C. (2004) · Endocrine Reviews · doi:10.1210/er.2002-0032 · Cited by 1,780
In vivo amplification of the androgen receptor gene and progression of human prostate cancer
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Self-citationThe Androgen Axis in Recurrent Prostate Cancer
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Cited by
EDC-2: the endocrine society's second scientific statement on endocrine-disrupting chemicals
Gore, A. C., Chappell, V. A., Fenton, S. E., Flaws, J. A., Nadal, A., Prins, G. S., Toppari, J., & Zoeller, R. T. (2015) · Endocrine Reviews · doi:10.1210/er.2015-1010 · Cited by 2,407
Metadata
- Authors
- Green, S. M., Mostaghel, E. A., & Nelson, P. S.
- Venue
- Molecular and Cellular Endocrinology
- Publisher
- Elsevier BV
- Published
- 2012-09
- Volume
- 360
- Issue
- 1-2
- Pages
- 3-13
- ISSN
- 0303-7207 (ISSN-L)
- OpenAlex
- W1995103673
- Cited by
- 181
- References
- 20
- FWCI
- 14.94
- Type
- journal article
- Language
- en
- Open access
- green
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- Green, S. M., Mostaghel, E. A., & Nelson, P. S. (2012). Androgen action and metabolism in prostate cancer. Molecular and Cellular Endocrinology. https://doi.org/10.1016/j.mce.2011.09.046
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
