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Plasma metabolomic profile in nonalcoholic fatty liver disease

Kalhan, Satish C., Guo, Lining, Edmison, John, Dasarathy, Srinivasan, McCullough, Arthur J., Hanson, Richard W., Milburn, Mike·2011·Metabolism
DOI 10.1016/j.metabol.2010.03.006PMC PMC2950914
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  • Elevated circulating bile acids are associated with NAFLD risk factors; metabolomic studies show global alterations in bile acid composition in steatosis; bile acids have been studied as a therapeutic target in NAFLD.

    “Elevated circulating levels of bile acids have been associated with major risk factors for non-alcoholic fatty liver disease (NAFLD), including insulin resistance and type 2 diabetes mellitus [43,44]. In addition, metabolomic studies conducted in the adult population have revealed global alterations in bile acid composition in individuals with simple steatosis compared with healthy controls [45,46”

    From Metabolomic Analysis of Pediatric Patients with Idiosyncratic Drug-Induced Liver Injury According to the Updated RUCAM (2023) · cites this paper as [46]

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Citations

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Research works printed but not linked: 34

  1. Preiss, 2008, Non-alcoholic fatty liver disease: an overview of prevalence, diagnosis, pathogenesis and treatment considerations, Clin Sci, 115, 141, 10.1042/CS20070402 · DOI
  2. Angulo, 2002, Nonalcoholic fatty liver disease, N Engl J Med, 346, 1221, 10.1056/NEJMra011775 · DOI · Paper page
  3. Byrne, 2009, Metabolic disturbances in non-alcoholic fatty liver disease, Clin Sci, 116, 539, 10.1042/CS20080253 · DOI
  4. Gibney, 2005, Metabolomics in human nutrition: opportunities and challenges, Am J Clin Nutr, 682, 497, 10.1093/ajcn/82.3.497 · DOI
  5. Wishart, 2007, Current progress in computational metabolomics, Brief Bioinform, 8, 279, 10.1093/bib/bbm030 · DOI
  6. Hollywood, 2006, Metabolomics: current technologies and future trends, Proteomics, 6, 4716, 10.1002/pmic.200600106 · DOI
  7. Evans, 2009, Integrated, nontargeted ultrahigh performance liquid chromatography/electrospray ionization tandem mass spectrometry platform for the identification and relative quantification of the small-molecule complement of biological systems, Anal Chem, 81, 6656, 10.1021/ac901536h · DOI
  8. Kleiner, 2005, Design and validation of a histological scoring system for nonalcoholic fatty liver disease, Hepatology, 41, 1313, 10.1002/hep.20701 · DOI · Paper page
  9. Garcia, 2002, Plasma total homocysteine quantification: an improvement of the classical high-performance liquid chromatographic method with fluorescence detection of the thiol-SBD derivatives, J Chromatogr B Analyt Technol Biomed Life Sci, 779, 359, 10.1016/S1570-0232(02)00401-4 · DOI
  10. Pennington, 1978, Serum bile acids in patient with hyperlipidaemia, J Clin Pathol, 31, 58, 10.1136/jcp.31.1.58 · DOI
  11. Bouchier, 1978, Serum bile acids in hepatobiliary disease, Gut, 19, 492, 10.1136/gut.19.6.492 · DOI
  12. Brody, 1979, Clearance tests of liver function, Med Clin North Am, 63, 621, 10.1016/S0025-7125(16)31692-3 · DOI
  13. Wei, 2009, Bile acids and insulin resistance: implications for treating nonalcoholic fatty liver disease, J Dig Dis, 10, 85, 10.1111/j.1751-2980.2009.00369.x · DOI
  14. Nerfi, 1978, Bile acid pool changes and regulation of cholate synthesis in experimental diabetes, Biochim Biophys Acta, 529, 212, 10.1016/0005-2760(78)90064-4 · DOI
  15. Uchida, 1978, Altered bile acid metabolism in alloxan diabetic rats, Jpn J Pharmacol, 29, 553, 10.1254/jjp.29.553 · DOI
  16. Ishida, 2000, Insulin is a dominant suppressor of sterol 12α-hydroxylase P450 (CYP8B) expression in rat liver: possible role of insulin in circadian rhythm of CYP8B, J Biochem, 127, 57, 10.1093/oxfordjournals.jbchem.a022584 · DOI
  17. Biddinger, 2008, Hepatic insulin resistance directly promotes formation of cholesterol gallstones, Nat Med, 14, 778, 10.1038/nm1785 · DOI
  18. Aanlungo, 2008, Insulin and cholesterol gallstones: new insights for a complex pathogenic relationship, Hepatology, 48, 2078, 10.1002/hep.22618 · DOI
  19. Houten, 2006, Endocrine functions of bile acids, EMBO J, 25, 1419, 10.1038/sj.emboj.7601049 · DOI
  20. Keitel, 2008, Endocrine and paracrine role of bile acids, World J Gastroenterol, 14, 5620, 10.3748/wjg.14.5620 · DOI
  21. Staels, 2009, Bile acids and metabolic regulation. Mechanisms and clinical response to bile acid sequestration, Diabetes Care, 32, S237, 10.2337/dc09-S355 · DOI
  22. Shigesawa, 1992, Significance of plasma glutathione determination in patients with alcoholic and non-alcoholic liver disease, J Gastroenterol Hepatol, 7, 7, 10.1111/j.1440-1746.1992.tb00926.x · DOI
  23. Altomar, 1988, Hepatic glutathione content in patients with alcoholic and non alcoholic liver diseases, Life Sci, 43, 991, 10.1016/0024-3205(88)90544-9 · DOI
  24. Franco, 2007, The central role of glutathione in the pathophysiology of human disease, Arch Physiol Biochem, 113, 234, 10.1080/13813450701661198 · DOI
  25. Dasarathy, 2009, Glycine and urea kinetics in non-alcoholic steatohepatitis in human: effect of intralipid infusion, Am J Physiol Gastrointest Liver Physiol, 297, G567, 10.1152/ajpgi.00042.2009 · DOI
  26. Bugianesi, 2005, Insulin resistance in non-diabetic patient with non-alcoholic fatty liver disease: sites and mechanisms, Diabetologia, 48, 634, 10.1007/s00125-005-1682-x · DOI · Paper page
  27. Sanyal, 2001, Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities, Gastroenterology, 120, 1183, 10.1053/gast.2001.23256 · DOI · Paper page
  28. Darmaun, 2005, Evidence for accelerated rates of glutathione utilization and glutathione depletion in adolescents with poorly controlled type 1 diabetes, Diabetes, 54, 190, 10.2337/diabetes.54.1.190 · DOI
  29. Puri, 2007, A lipidomic analysis of nonalcoholic fatty liver disease, Hepatology, 46, 1081, 10.1002/hep.21763 · DOI · Paper page
  30. Newgard, 2009, A branched-chain amino acid–related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance, Cell Metab, 9, 311, 10.1016/j.cmet.2009.02.002 · DOI · Paper page
  31. Marliss, 2006, Elevations of plasma methylarginines in obesity and ageing are related to insulin sensitivity and rates of protein turnover, Diabetologia, 49, 351, 10.1007/s00125-005-0066-6 · DOI
  32. Pereira, 2008, Insulin resistance of protein metabolism in type 2 diabetes, Diabetes, 57, 56, 10.2337/db07-0887 · DOI
  33. Gougeon, 2008, Determinants of whole-body protein metabolism in subjects with and without type 2 diabetes, Diabetes Care, 31, 128, 10.2337/dc07-1268 · DOI
  34. Kalhan, 2009, Fatty acids, insulin resistance and protein metabolism, J Clin Endocrinol Metab, 94, 2725, 10.1210/jc.2009-1235 · DOI

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Metadata

Authors
Kalhan, S. C., Guo, L., Edmison, J., Dasarathy, S., McCullough, A. J., Hanson, R. W., & Milburn, M.
Venue
Metabolism
Publisher
Elsevier BV
Published
2011-03
Volume
60
Issue
3
Pages
404-413
ISSN
0026-0495
DOI
10.1016/j.metabol.2010.03.006
PMC
PMC2950914
Cited by
532
References
2
Language
en
Licence
Funders
  • Cleveland Clinic Foundation (DK079937)
  • National Institutes of Health

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