Microbial genomes and vaccine design: refinements to the classical reverse vaccinology approach

Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd

Fleischmann, R. D., Adams, M. D., White, O. R., Clayton, R. A., Kirkness, E. F., Kerlavage, A. R., Bult, C. J., Tomb, J.-F., Dougherty, B. A., Merrick, J. M., et al. (1995) · Science · doi:10.1126/science.7542800 · Cited by 5,641 · see citing works

Multilocus sequence typing: A portable approach to the identification of clones within populations of pathogenic microorganisms

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Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae : Implications for the microbial “pan-genome”

Tettelin, H., Masignani, V., Cieslewicz, M. J., Donati, C., Medini, D., Ward, N. L., Angiuoli, S. V., Crabtree, J., Jones, A. L., Durkin, A. S., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506758102 · Cited by 2,644 · see citing works

How clonal are bacteria?

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Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli

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Identification of Vaccine Candidates Against Serogroup B Meningococcus by Whole-Genome Sequencing

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Identification of a Universal Group B <i>Streptococcus</i> Vaccine by Multiple Genome Screen

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Recombination within natural populations of pathogenic bacteria: Short-term empirical estimates and long-term phylogenetic consequences

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Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae

Tettelin, H., Masignani, V., Cieslewicz, M. J., Eisen, J. A., Peterson, S. N., Wessels, M. R., Paulsen, I. T., Nelson, K. E., Margarit, I., Read, T. D., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.182380799 · Cited by 501 · see citing works

Genome sequence of Streptococcus agalactiae, a pathogen causing invasive neonatal disease

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Global Phylogeny ofMycobacterium tuberculosisBased on Single Nucleotide Polymorphism (SNP) Analysis: Insights into Tuberculosis Evolution, Phylogenetic Accuracy of Other DNA Fingerprinting Systems, and Recommendations for a Minimal Standard SNP Set

Filliol, I., Motiwala, A. S., Cavatore, M., Qi, W., Hazbón, M. H., Bobadilla-del-Valle, M., Fyfe, J., García‐García, L., Rastogi, N., Sola, C., et al. (2005) · Journal of Bacteriology · doi:10.1128/jb.188.2.759-772.2006 · Cited by 431 · see citing works

Genotypic Diversity Within a Natural Coastal Bacterioplankton Population

Thompson, J. R., Preheim, S. P., Pharino, C., Klepac‐Ceraj, V., Hunt, D. E., Benoit, J., Sarma-Rupavtarm, R. B., Distel, D. L., & Polz, M. F. (2005) · Science · doi:10.1126/science.1106028 · Cited by 360 · see citing works

Use of a Whole Genome Approach To Identify Vaccine Molecules Affording Protection against Streptococcus pneumoniae Infection

Wizemann, T. M., Heinrichs, J. H., Adamou, J. E., Erwin, A. L., KUNSCH, C. A., Choi, G. H., Barash, S. C., Rosen, C. A., Masure, H. R., TUOMANEN, E. I., et al. (2001) · Infection and Immunity · doi:10.1128/iai.69.3.1593-1598.2001 · Cited by 351 · see citing works

The relative contributions of recombination and mutation to the divergence of clones of Neisseria meningitidis

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GENETIC DIVERSITY AND TEMPORAL VARIATION IN THE E. COLI POPULATION OF A HUMAN HOST

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Summary of a Workshop on the Clone Concept in the Epidemiology, Taxonomy, and Evolution of the Enterobacteriaceae and other Bacteria

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A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T cell responses

Jackson, D. C., Lau, Y. F., Le, T., Suhrbier, A., Deliyannis, G., Cheers, C., Smith, C., Zeng, W., & Brown, L. E. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0406740101 · Cited by 236 · see citing works

Multilocus genetic structure in natural populations of Escherichia coli.

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Genomic Approach for Analysis of Surface Proteins inChlamydia pneumoniae

Montigiani, S., Falugi, F., Scarselli, M., et al. (2002) · Infection and Immunity · doi:10.1128/iai.70.1.368-379.2002 · Cited by 200 · see citing works

Distribution of Surface Protein Variants among Hyperinvasive Meningococci: Implications for Vaccine Design

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Immunomics: discovering new targets for vaccines and therapeutics

Groot, A. S. D. (2006) · Drug Discovery Today · doi:10.1016/s1359-6446(05)03720-7 · Cited by 153 · see citing works

Identification of vaccine candidate antigens from a genomic analysis of Porphyromonas gingivalis

Ross, B. C., Czajkowski, L., Hocking, D. M., et al. (2001) · Vaccine · doi:10.1016/s0264-410x(01)00173-6 · Cited by 140 · see citing works

Search for Potential Vaccine Candidate Open Reading Frames in theBacillus anthracisVirulence Plasmid pXO1: In Silico and In Vitro Screening

Ariel, N., Zvi, A., Grosfeld, H., Gat, O., Inbar, Y., Velan, B., Cohen, S. B., & Avigdor Shafferman, C. (2002) · Infection and Immunity · doi:10.1128/iai.70.12.6817-6827.2002 · Cited by 121 · see citing works

The potential impact of structural genomics on tuberculosis drug discovery

Arcus, V. L., Lott, J. S., Johnston, J. M., & Baker, E. N. (2006) · Drug Discovery Today · doi:10.1016/s1359-6446(05)03667-6 · Cited by 42 · see citing works

Intranasal vaccination with SfbI or M protein-derived peptides conjugated to diphtheria toxoid confers protective immunity against a lethal challenge with Streptococcus pyogenes

Schulze, K., Olive, C., Ebensen, T., et al. (2006) · Vaccine · doi:10.1016/j.vaccine.2006.05.024 · Cited by 31 · see citing works

Untitled work

(2001) · doi:10.1002/1521-4141(200112)31:12

Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

McLellan, J. S., Chen, M., Joyce, M. G., Sastry, M., Stewart-Jones, G. B. E., Yang, Y., Zhang, B., Chen, L., Srivatsan, S., Zheng, A., et al. (2013) · Science · doi:10.1126/science.1243283 · Cited by 1,126 · see citing works

Comparative genomics: the bacterial pan-genome

Tettelin, H., Riley, D., Cattuto, C., & Medini, D. (2008) · Current Opinion in Microbiology · doi:10.1016/j.mib.2008.09.006 · Cited by 1,120 · see citing works

Reverse Vaccinology and Vaccines for Serogroup B Neisseria meningitidis

Kelly, D. F., & Rappuoli, R. (2007) · Springer eBooks · doi:10.1007/0-387-25342-4_15 · Cited by 62 · see citing works

Reverse vaccinology, a genome-based approach to vaccine development

Rappuoli, R. (2001) · Vaccine · doi:10.1016/s0264-410x(00)00554-5 · Cited by 497 · see citing works

Application of reverse vaccinology in vaccine research and development of infectious diseases

Li, Z., Lv, Z., & Wu, Z. (2008) · Int J Med Parasit Dis · doi:10.3760/cma.j.issn.1673-4122.2008.02.008

Two years into reverse vaccinology

Adu‐Bobie, J. (2003) · Vaccine · doi:10.1016/s0264-410x(02)00566-2 · Cited by 150 · see citing works

Reverse Vaccinology in Plasmodium falciparum 3D7

Isea, R., Mayo Garcia, R., & Restrepo, S. (2016) · Journal of Immunological Techniques in Infectious Diseases · doi:10.4172/2329-9541.1000145 · Cited by 3 · see citing works