The DOI matches its Crossref record; 74 of the 74 references it cites were found in a registry or an index.
Klebsiella pneumoniae as a key trafficker of drug resistance genes from environmental to clinically important bacteria
Open accessAbstract
Klebsiella pneumoniae is an opportunistic bacterial pathogen known for its high frequency and diversity of antimicrobial resistance (AMR) genes. In addition to being a significant clinical problem in its own right, K. pneumoniae is the species within which several new AMR genes were first discovered before spreading to other pathogens (e.g. carbapenem-resistance genes KPC, OXA-48 and NDM-1). Whilst K. pneumoniae's contribution to the overall AMR crisis is impossible to quantify, current evidence suggests it has a wider ecological distribution, significantly more varied DNA composition, greater AMR gene diversity and a higher plasmid burden than other Gram negative opportunists. Hence we propose it plays a key role in disseminating AMR genes from environmental microbes to clinically important pathogens.
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Antibiotic resistance is ancient
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CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database
Jia, B., Raphenya, A. R., Alcock, B., Waglechner, N., Guo, P., Tsang, K. K., Lago, B. A., Dave, B. M., Pereira, S., Sharma, A. N., et al. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkw1004 · Cited by 2,661
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Platforms for antibiotic discovery
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Clinical relevance of the ESKAPE pathogens
Pendleton, J. N., Gorman, S. P., & Gilmore, B. F. (2013) · Expert Review of Anti-infective Therapy · doi:10.1586/eri.13.12 · Cited by 1,423
Klebsiella pneumoniae: a major worldwide source and shuttle for antibiotic resistance
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Cited by
Population genomics of Klebsiella pneumoniae
Wyres, K. L., Lam, M. M. C., & Holt, K. E. (2020) · Nature Reviews Microbiology · doi:10.1038/s41579-019-0315-1 · Cited by 1,160
Self-citationGuitor, A. K., Yousuf, E. I., Raphenya, A. R., Hutton, E. K., Morrison, K. M., McArthur, A. G., Wright, G. D., & Stearns, J. C. (2022) · Microbiome · doi:10.1186/s40168-022-01327-7 · Cited by 44
Diverse polysaccharide production and biofilm formation abilities of clinical Klebsiella pneumoniae
(2024) · doi:10.1038/s41522-024-00629-y · Cited by 29
Metadata
- Authors
- .Wyres, K. L., & Holt, K. E.
- Venue
- Current Opinion in Microbiology
- Publisher
- Elsevier BV
- Published
- 2018-10
- Volume
- 45
- Pages
- 131-139
- ISSN
- 1369-5274 (ISSN-L)
- OpenAlex
- W2803074811
- Cited by
- 685
- References
- 74
- FWCI
- 3.94
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- .Wyres, K. L., & Holt, K. E. (2018). Klebsiella pneumoniae as a key trafficker of drug resistance genes from environmental to clinically important bacteria. Current Opinion in Microbiology. https://doi.org/10.1016/j.mib.2018.04.004
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
