Cited by 41Fungal Biology and ApplicationsPolysaccharides Composition and ApplicationsMicrobial Natural Products and Biosynthesis

The DOI matches its Crossref record, with a small difference in title or year; 25 of the 28 references it cites were found in a registry or an index.

The antitumor and antioxidative activities of polysaccharides isolated from Isaria farinosa B05

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Jiang, Yan-hua, Jiang, Xiao-lu, Wang, Peng, Mou, Hai-jin, Hu, Xiao-ke, Liu, Shu-qing·2008·Microbiological Research

Abstract

The water-soluble intra-polysaccharides WIPS1 and water-soluble extra-polysaccharides WEPS1 were isolated from Isaria farinosa B05 through ethanol precipitation and gel permeation chromatography (GPC). Their characteristics were determined by chemical analysis, gas chromatography, GPC and IR spectroscopy. The results show that WIPS1 contained 90.3% carbohydrate, 8.00% uronic acid, 7.15% protein and three kinds of monosaccharides including mannose, galactose and glucose with a molar ratio of 8.0:4.8:1.0. WEPS1 contained 93.4% carbohydrate, 8.06% uronic acid, 4.40% protein and three kinds of monosaccharides including mannose, galactose and glucose with a molar ratio of 21.6:4.7:1.0. WIPS1 and WEPS1 had a molecular weight of 42 and 208kDa, respectively. The in vivo tests in mice indicate that WIPS1 and WEPS1 had significant antitumor and antioxidative activities to some extent.

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  1. An, 2003, Study on the physiological activities of metabolites from Paecilomces farinosus, J. Shanxi Agric. Univ., 2, 103
  2. Borchardt, 1970, A gas chromatographic method for carbohydrates as alditol-acetates, Tappi, 53, 257
  3. Li, 1997, Studies on exopolysaccharide (EPS) fermentation by Cordyceps militaris, and on its physical and chemical properties and antioxidation, J. Microbiol., 17, 13
  4. Song, 1998, The anti-complementary activities of exo-polymer produced from submerged culture of higher fungi with particular reference to Cordyceps militaris, Microbiol. Biotechnol., 8, 536
  5. Staub, 1965, Removal of protein – Sevag method, Methods Carbohyd. Chem., 5, 5

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Metadata

Authors
Jiang, Y.-H., Jiang, X.-L., Wang, P., Mou, H.-J., Hu, X.-K., & Liu, S.-Q.
Affiliations
Ocean University of China (CN)
Venue
Microbiological Research
Publisher
Elsevier BV
Published
2008-07
Volume
163
Issue
4
Pages
424-430
ISSN
0944-5013 (ISSN-L)
OpenAlex
W2071527686
Cited by
41
References
28
Citations by year
2026: 1 · 2025: 1 · 2024: 2 · 2023: 3 · 2022: 1 · 2021: 4 · 2020: 3 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 3 · 2015: 4 · 2014: 2 · 2013: 5 · 2012: 2
FWCI
0.42
Type
journal article
Language
en
Open access
Locations
  • Microbiological Research (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pharmacology (medical) › Fungal Biology and Applications
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
  • Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Microbial Natural Products and Biosynthesis
Keywords
Isaria farinosa, fungal polysaccharides, anticancer activity, antioxidant activity, uronic acid, monosaccharide composition, molecular weight, chemoprevention
MeSH terms
Animals, Antineoplastic Agents, Antioxidants, Carbohydrates, Catalase, Chromatography, Gas, Chromatography, Gel, Female, Chemical Fractionation, Hypocreales, Liver, Molecular Weight, Polysaccharides, Proteins, Sarcoma, Superoxide Dismutase, Uronic Acids, Spectroscopy, Fourier Transform Infrared, Mice

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CoChat. (2026). Citation check: The antitumor and antioxidative activities of polysaccharides isolated from Isaria farinosa B05. https://app.cochat.ai/papers/10.1016/j.micres.2006.07.002
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Jiang, Y.-H., Jiang, X.-L., Wang, P., Mou, H.-J., Hu, X.-K., & Liu, S.-Q. (2008). The antitumor and antioxidative activities of polysaccharides isolated from Isaria farinosa B05. Microbiological Research. https://doi.org/10.1016/j.micres.2006.07.002