p97: The Cell's Molecular Purgatory?

Halawani, Dalia, Latterich, Martin·2006·Molecular Cell
DOI 10.1016/j.molcel.2006.06.003

Cited by (145)

Items 101–145 of 145

  1. Mutant p97 exhibits species-specific changes of its ATPase activity and compromises the UBXD9-mediated monomerisation of p97 hexamers
    Ramesh Rijal, Khalid Arhzaouy, Karl-Heinz Strucksberg, Megan Cross, Andreas Hofmann, Rolf Schröder, Christoph Stephan Clemen, Ludwig Eichinger · 2016 · European Journal of Cell Biology
  2. The Tissue-Specific Rep8/UBXD6 Tethers p97 to the Endoplasmic Reticulum Membrane for Degradation of Misfolded Proteins
    Louise Madsen, Franziska Kriegenburg, Andrea Vala, Diana Best, Søren Prag, Kay Hofmann, Michael Seeger, Ian R. Adams, Rasmus Hartmann‐Petersen · 2011 · PLoS ONE
  3. Evaluating p97 Inhibitor Analogues for Potency against p97–p37 and p97–Npl4–Ufd1 Complexes
    Lin Gui, Xiaoyi Zhang, Kelin Li, Kevin J. Frankowski, Shan Li, Daniel Wong, Derek R. Moen, Patrick R. Porubsky, Henry J. Lin, Frank J. Schoenen et al. · 2016 · ChemMedChem
  4. Amino acid analog toxicity in primary rat neuronal and astrocyte cultures: Implications for protein misfolding and TDP‐43 regulation
    Kalavathi Dasuri, Philip J. Ebenezer, Romina María Uranga, Elena Gavilán, Le Zhang, Sun Ok Fernandez‐Kim, Annadora J. Bruce‐Keller, Jeffrey N. Keller · 2011 · Journal of Neuroscience Research
  5. Identification of Lysines within Membrane-Anchored Mga2p120 that Are Targets of Rsp5p Ubiquitination and Mediate Mobilization of Tethered Mga2p90
    Sabyasachi Bhattacharya, Natalia Shcherbik, Julian Vasilescu, Jeffrey C. Smith, Daniel Figeys, Dale S. Haines · 2008 · Journal of Molecular Biology
  6. mRNA Processing Factor CstF-50 and Ubiquitin Escort Factor p97 Are BRCA1/BARD1 Cofactors Involved in Chromatin Remodeling during the DNA Damage Response
    Danae Fonseca, Jorge Baquero, Michael Robert Murphy, Gamage Aruggoda, Sophia Varriano, Carmen Sapienza, Oksana Mashadova, Shadaqur Rahman, Frida E. Kleiman · 2017 · Molecular and Cellular Biology
  7. Molecular Mechanisms Driving and Regulating the AAA+ ATPase VCP/p97, an Important Therapeutic Target for Treating Cancer, Neurological and Infectious Diseases
    Sepideh Valimehr, Ashish Sethi, Manjari Shukla, Sudipta Bhattacharyya, Mohsen Kazemi, Isabelle Rouiller · 2023 · Biomolecules
  8. Valosin containing protein (VCP/p97) is a novel substrate for the protein tyrosine phosphatase PTPL1
    Ogan D. Abaan, Wiljan J A J Hendriks, Aykut Üren, Jeffrey A. Toretsky, Hayriye Verda Erkizan · 2012 · Experimental Cell Research
  9. The emerging role of deubiquitination in nucleotide excision repair
    Ling Zhang, Feng Gong · 2016 · DNA repair
  10. The heterozygous R155C VCP mutation: Toxic in humans! Harmless in mice?
    Christoph Stephan Clemen, Lilli Winter, Karl-Heinz Strucksberg, Carolin Berwanger, Matthias Türk, Cornelia Kornblum, Alexandra Florin, Juan Antonio Aguilar‐Pimentel, Oana Veronica Amarie, Lore Becker et al. · 2018 · Biochemical and Biophysical Research Communications
  11. CHIP promotes the degradation of mutant SOD1 by reducing its interaction with VCP and S6/S6′ subunits of 26S proteasome
    Jin-Sun Choi, Do Hee Lee · 2010 · Animal Cells and Systems
  12. Cryo-EM of the pathogenic VCP variant R155P reveals long-range conformational changes in the D2 ATPase ring
    Driss Mountassif, Lucien Fabre, Younes Zaid, Dalia Halawani, Isabelle Rouiller · 2015 · Biochemical and Biophysical Research Communications
  13. Motor Neuron Disease
    Teepu Siddique, Han‐Xiang Deng, Senda Ajroud‐Driss · 2013 · Elsevier eBooks
  14. Another VCP interactor: NF is enough
    Conrad Chris Weihl · 2011 · Journal of Clinical Investigation
  15. VCP-related myopathy: a case series and a review of literature.
    Eliana Iannibelli, Sara Gibertini, Marta Cheli, Flavia Blàsevich, Andrea Cavaliere, Giorgia Riolo, Alessandra Ruggieri, Lorenzo Maggi · 2023 · Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology / edited by the Gaetano Conte Academy for the study of striated muscle diseases
  16. Inhibition of p97/VCP function leads to defective autophagosome maturation, cell cycle arrest and apoptosis in mouse Sertoli cells
    Sevil Çaylı, Cansu Sahin, Tuba Özdemir Sancı, Hilal Nakkaş · 2020 · Theriogenology
  17. Target deletion of the AAA ATPase PpCDC48II in Physcomitrella patens results in freezing sensitivity after cold acclimation
    Hui Wang, Shuo Jin, Xi Chen, XuKe Gen, Yikun He · 2012 · Science China Life Sciences
  18. Model Systems of Motor Neuron Diseases As a Platform for Studying Pathogenic Mechanisms and Searching for Therapeutic Agents
    Kamila R. Valetdinova, Sergey P. Medvedev, Suren M. Zakian · 2015 · Acta Naturae
  19. Endoplasmic Reticulum (ER) Stress in Amyotrophic Lateral Sclerosis (ALS)
    Han-Jou Chen, Jacqueline de Belleroche · 2012 · Springer eBooks
  20. Cdc48 and its co-factor Ufd1 extract CENP-A from centromeric chromatin and can induce chromosome elimination in the fission yeast Schizosaccharomyces pombe
    Yukiko Nakase, Hiroaki Murakami, Michiko Suma, Kaho Nagano, Airi Wakuda, Teppei Kitagawa, Tomohiro Matsumoto · 2024 · Biology Open
  21. Energy-sensing molecule RORγ regulates cholesterol metabolism and immune signaling in diabetic kidney disease and aging
    Zhen Liang, Jiaqing Xiang, Guangyan Yang, Xiaomai Liu, Lei Li, Yanchun Li, Yan Lü, Lin Kang, Yuanli Chen, Chuanrui Ma et al. · 2026 · Nature Communications
  22. Purification, crystallization and preliminary X-ray diffraction analysis of disease-related mutants of p97
    Wai‐Kwan Tang, Dongyang Li, Lothar Esser, Di Xia · 2009 · Acta Crystallographica Section F Structural Biology and Crystallization Communications
  23. Seasonal proteomic plasticity in the brain of a mammalian hibernator
    Woojae Yoo, Kisoo Lee, Taesik Gwag, Hyunwoo Ju, Masamichi Yamashita, Inho Choi · 2008 · Biological Sciences in Space
  24. p97 Adaptor Choice Regulates Organelle Biogenesis
    Martin Latterich · 2006 · Developmental Cell
  25. Valosin-Containing Protein (VCP) Disease and Familial Alzheimer’s Disease: Contrasts and Overlaps
    CD Smith, Mallikarjun Badadani, Angèle Nalbandian, Eric Dec, Jouni Vesa, Sandra C. Donkervoort, B Martin, GD Watts, Vincent J. Caiozzo, Virginia E. Kimonis · 2011 · InTech eBooks
  26. Cellular responses to unsaturated fatty acids mediated by their sensor Ubxd8
    Jin Ye · 2012 · Frontiers in Biology
  27. Nrf1 to the rescue
    Jin Ye · 2014 · eLife
  28. 小立碗藓PpCDC48II 基因的定点敲除导致冷驯化后的冻害敏感
    曦 陈, 慧 王, 奕 何, 硕 谨, 旭珂 耿 · 2012 · Scientia Sinica Vitae
  29. MicroRNAs Regulating Autophagy in Neurodegeneration
    Qingxuan Lai, Nikolai Kovzel, Ruslan Konovalov, Ilya A. Vinnikov · 2021 · Advances in experimental medicine and biology
  30. To Degrade or not to Degrade : Protein Handling by the Proteasome
    Christian Heinen · 2010 · Figshare
  31. Proteomics of the endoplasmic reticulum to determine cellular organization and protein function
    Michael David Jain · 2009
  32. The basis of VCP-mediated degeneration: Insights from a Drosophila model of disease
    Gillian P. Ritson · 2010 · Scholarly Commons (University of Pennsylvania)
  33. Proteins of Autophagy: LAMP‐2, VMA21, VCP, and TRIM32
    May Christine V. Malicdan, Ichizo Nishino · 2013
  34. Endoplasmic reticulum associated protein degradation (ERAD): the function of Dfm1 and other novel components of the pathway
    Alexandra Stolz · 2011 · OPUS Publication Server of the University of Stuttgart (University of Stuttgart)
  35. Drosophila and Mouse Models of Hereditary Myopathy Caused by Mutations in VCP/p97
    Nisha M. Badders, J. Paul Taylor · 2011
  36. Axon Death Prevented: Wlds and Other Neuroprotective Molecules: A Dissertation
    Michelle A. Avery · 2010 · eScholarship@UMassChan
  37. Role of the Polyadenylation Factor CstF-50 in regulating the BRCA1/BARD1 E3 Ubiquitin (Ub) Ligase Activity
    Danae Fonseca · 2014 · CUNY Academic Works (City University of New York)
  38. Identifizierung und Charakterisierung von neuen Kandidatengenen bei hereditären Skelettmuskelerkrankungen mit kardialer Beteiligung
    Marianne Dieterich · 2014
  39. Publisher’s Note
    2016 · DNA repair
  40. AAA-ATPases
    Jörg Martin, A.N. Lupas · 2013 · Encyclopedia of Biological Chemistry
  41. Cdc48 and its co-factor Ufd1 segregate CENP-A from centromeric chromatin and can induce chromosome elimination in the fission yeast Schizosaccharomyces pombe
    Yukiko Nakase, Hiroaki Murakami, Michiko Suma, Kaho Nagano, Airi Wakuda, Teppei Kitagawa, Tomohiro Matsumoto · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  42. Analyses génétiques et fonctionnelles de nouveaux gènes incriminés dans la Sclérose Latérale Amyotrophique (SLA)
    Elisa Teyssou · 2017 · theses.fr (ABES)
  43. Recent advances in p97/VCP/Cdc48 cellular functions
    邦俊 山中, Yohei Sasagawa, 小椋 光, Kunitoshi Yamanaka, Teru Ogura · Institutional Repositories DataBase (IRDB)
  44. The Autophagic Interaction Between p97/VCP and ABP Protein Expressions in Sertoli Cell Line: the Effects of Chloroquine and Rapamycin
    İlkay Pişkin, Sevil Çaylı · 2026 · Reproductive Sciences
  45. BindingDB Entry 50047382: Oxaspirol B with p97 Inhibitory Activity and Other Oxaspirols from Lecythophora sp. FL1375 and FL1031, Endolichenic Fungi Inhabiting Parmotrema tinctorum and Cladonia evansii.
    BindingDB · 2017 · UC San Diego