Mechanism of Actin Filament Turnover by Severing and Nucleation at Different Concentrations of ADF/Cofilin

ADF/Cofilin: a functional node in cell biology

Bernstein, B. W., & Bamburg, J. R. (2010) · Trends in Cell Biology · doi:10.1016/j.tcb.2010.01.001 · Cited by 704

Structural and Molecular Remodeling of Dendritic Spine Substructures during Long-Term Potentiation

Bosch, M., Castro, J., Saneyoshi, T., Matsuno, H., Sur, M., & Hayashi, Y. (2014) · Neuron · doi:10.1016/j.neuron.2014.03.021 · Cited by 637

Phosphoinositide signalling in cancer: beyond PI3K and PTEN

Bunney, T. D., & Katan, M. (2010) · Nature Reviews Cancer · doi:10.1038/nrc2842 · Cited by 400

Signaling mechanisms and functional roles of cofilin phosphorylation and dephosphorylation

Mizuno, K. (2013) · Cellular Signalling · doi:10.1016/j.cellsig.2012.11.001 · Cited by 396

Ins and outs of ADF/cofilin activity and regulation

Van Troys, M., Huyck, L., Leyman, S., Dhaese, S., Vandekerkhove, J., & Ampe, C. (2008) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2008.04.001 · Cited by 329

Cdc42 regulates cofilin during the establishment of neuronal polarity.

Garvalov, B. K., Flynn, K. C., Neukirchen, D., Meyn, L., Teusch, N., Wu, X., Brakebusch, C., Bamburg, J. R., & Bradke, F. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.3322-07.2007 · Cited by 262

EGF-induced PIP2 hydrolysis releases and activates cofilin locally in carcinoma cells

van Rheenen, J., Song, X., van Roosmalen, W., Cammer, M., Chen, X., DesMarais, V., Yip, S.-C., Backer, J. M., Eddy, R. J., & Condeelis, J. S. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200706206 · Cited by 244

Cofilin Tunes the Nucleotide State of Actin Filaments and Severs at Bare and Decorated Segment Boundaries

Suarez, C., Roland, J., Boujemaa-Paterski, R., Kang, H., McCullough, B. R., Reymann, A.-C., Guérin, C., Martiel, J.-L., De La Cruz, E. M., & Blanchoin, L. (2011) · Current Biology · doi:10.1016/j.cub.2011.03.064 · Cited by 223

Plasticity of Spine Structure: Local Signaling, Translation and Cytoskeletal Reorganization

Nakahata, Y., & Yasuda, R. (2018) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2018.00029 · Cited by 209

Stepwise synaptic plasticity events drive the early phase of memory consolidation

Goto, A., Bota, A., Miya, K., Wang, J., Tsukamoto, S., Jiang, X., Hirai, D., Murayama, M., Matsuda, T., McHugh, T. J., et al. (2021) · Science · doi:10.1126/science.abj9195 · Cited by 184

Actin dynamics and cofilin‐actin rods in alzheimer disease

Bamburg, J. R., & Bernstein, B. W. (2016) · Cytoskeleton · doi:10.1002/cm.21282 · Cited by 181

ADF/Cofilin-Actin Rods in Neurodegenerative Diseases

Bamburg, J. R., Bernstein, B. W., Davis, R. C., Flynn, K. C., Goldsbury, C., Jensen, J. R., Maloney, M. T., Marsden, I. T., Minamide, L. S., Pak, C. W., et al. (2010) · Current Alzheimer Research · doi:10.2174/156720510791050902 · Cited by 173

Mechanistic principles underlying regulation of the actin cytoskeleton by phosphoinositides

Senju, Y., Kalimeri, M., Koskela, E. V., Somerharju, P., Zhao, H., Vattulainen, I., & Lappalainen, P. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1705032114 · Cited by 118

Actin mediates the nanoscale membrane organization of the clustered membrane protein influenza hemagglutinin

Gudheti, M. V., Curthoys, N. M., Gould, T. J., Kim, D., Gunewardene, M. S., Gabor, K. A., Gosse, J. A., Kim, C. H., Zimmerberg, J., & Hess, S. T. (2013) · Biophysical Journal · doi:10.1016/j.bpj.2013.03.054 · Cited by 106

MEDYAN: mechanochemical simulations of contraction and polarity alignment in actomyosin networks

Popov, K., Komianos, J., & Papoian, G. A. (2016) · PLOS Computational Biology · doi:10.1371/journal.pcbi.1004877 · Cited by 104

Cofilin Aggregation Blocks Intracellular Trafficking and Induces Synaptic Loss in Hippocampal Neurons

Cichon, J., Sun, C., Chen, B., Jiang, M., Chen, X. A., Sun, Y., Wang, Y., & Chen, G. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.301911 · Cited by 95

Activated Actin-Depolymerizing Factor/Cofilin Sequesters Phosphorylated Microtubule-Associated Protein during the Assembly of Alzheimer-Like Neuritic Cytoskeletal Striations

Whiteman, I. T., Gervasio, O. L., Cullen, K. M., Guillemin, G. J., Jeong, E. V., Witting, P. K., Antao, S. T., Minamide, L. S., Bamburg, J. R., & Goldsbury, C. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.3531-09.2009 · Cited by 92

The natural product cucurbitacin E inhibits depolymerization of actin filaments

Sörensen, P. M., Iacob, R. E., Fritzsche, M., Engen, J. R., Brieher, W. M., Charras, G., & Eggert, U. S. (2012) · ACS Chemical Biology · doi:10.1021/cb300254s · Cited by 61

Shigella depends on SepA to destabilize the intestinal epithelial integrity via cofilin activation

Maldonado-Contreras, A., Birtley, J. R., Boll, E., Zhao, Y., Mumy, K. L., Toscano, J., Ayehunie, S., Reinecker, H.-C., Stern, L. J., & McCormick, B. A. (2017) · Gut Microbes · doi:10.1080/19490976.2017.1339006 · Cited by 57

Cyclase-associated protein 2 dimerization regulates cofilin in synaptic plasticity and Alzheimer's disease

Pelucchi, S., Vandermeulen, L., Pizzamiglio, L., Aksan, B., Yan, J., Konietzny, A., Bonomi, E., Borroni, B., Padovani, A., Rust, M. B., et al. (2020) · Brain Communications · doi:10.1093/braincomms/fcaa086 · Cited by 55

Roles of LIM kinases in central nervous system function and dysfunction

Cuberos, H., Vallée, B., Vourc'h, P., Tastet, J., Andres, C. R., & Bénédetti, H. (2015) · FEBS Letters · doi:10.1016/j.febslet.2015.10.032 · Cited by 54

Bin1 directly remodels actin dynamics through its BAR domain

Dräger, N. M., Nachman, E., Winterhoff, M., Brühmann, S., Shah, P., Katsinelos, T., Boulant, S., Teleman, A. A., Faix, J., & Jahn, T. R. (2017) · The EMBO Reports · doi:10.15252/embr.201744137 · Cited by 51

Cofilactin filaments regulate filopodial structure and dynamics in neuronal growth cones

Hylton, R. K., Heebner, J. E., Grillo, M. A., & Swulius, M. T. (2022) · Nature Communications · doi:10.1038/s41467-022-30116-x · Cited by 45

Regulation of postsynaptic signaling in structural synaptic plasticity

Fu, A. K., & Ip, N. Y. (2017) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2017.05.016 · Cited by 43

A Temporal Model of Cofilin Regulation and the Early Peak of Actin Barbed Ends in Invasive Tumor Cells

Tania, N., Prosk, E., Condeelis, J., & Edelstein-Keshet, L. (2011) · Biophysical Journal · doi:10.1016/j.bpj.2011.02.036 · Cited by 32

Gliotoxin Induces Cofilin Phosphorylation to Promote Actin Cytoskeleton Dynamics and Internalization of Aspergillus fumigatus Into Type II Human Pneumocyte Cells

Zhang, C., Chen, F., Liu, X., Han, X., Hu, Y., Su, X., Chen, Y., Sun, Y., & Han, L. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.01345 · Cited by 29

Structural basis underlying specific biochemical activities of non-muscle tropomyosin isoforms

Selvaraj, M., Kokate, S. B., Reggiano, G., Kogan, K., Kotila, T., Kremneva, E., DiMaio, F., Lappalainen, P., & Huiskonen, J. T. (2023) · Cell Reports · doi:10.1016/j.celrep.2022.111900 · Cited by 22

RhoA/Rock2/Limk1/cofilin1 pathway is involved in attenuation of neuronal dendritic spine loss by paeonol in the frontal cortex of D-galactose and aluminum-induced Alzheimer’s disease-like rat model

Han, F., Xu, H., Shen, J.-X., Pan, C., Yu, Z.-H., Chen, J.-J., Zhu, X.-L., Cai, Y.-F., & Lu, Y.-P. (2020) · Acta Neurobiologiae Experimentalis · doi:10.21307/ane-2020-021 · Cited by 18

CryoET shows cofilactin filaments inside the microtubule lumen

Ventura Santos, C., Rogers, S. L., & Carter, A. P. (2023) · The EMBO Reports · doi:10.15252/embr.202357264 · Cited by 11

Deciphering the Cofilin Oligomers via Intermolecular Disulfide Bond Formation: A Coarse-Grained Molecular Dynamics Approach to Understanding Cofilin’s Regulation on Actin Filaments

Li, C., Wei, T.-Y., Cheung, M. S., & Tsai, M.-Y. (2024) · The Journal of Physical Chemistry B · doi:10.1021/acs.jpcb.3c07938 · Cited by 1