An Acetylation Site in the Middle Domain of Hsp90 Regulates Chaperone Function

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Items 101–200 of 421

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  8. Acetylation Directs Survivin Nuclear Localization to Repress STAT3 Oncogenic Activity
    Haijuan Wang, Michael P. Holloway, Li Ma, Zachary Aaron Cooper, Matthew Riolo, Ayman Samkari, Kojo S.J. Elenitoba‐Johnson, Yue Eugene Chin, Rachel A. Altura · 2010 · Journal of Biological Chemistry
  9. HDAC4 Controls Muscle Homeostasis through Deacetylation of Myosin Heavy Chain, PGC-1α, and Hsc70
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  10. Inhibitors of Deacetylases Suppress Oncogenic KIT Signaling, Acetylate HSP90, and Induce Apoptosis in Gastrointestinal Stromal Tumors
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  14. Inhibition of Apoptosome Formation by Suppression of Hsp90β Phosphorylation in Tyrosine Kinase-Induced Leukemias
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  17. Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain
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  18. MEC-17 Deficiency Leads to Reduced α-Tubulin Acetylation and Impaired Migration of Cortical Neurons
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  19. HDAC6 deacetylates p53 at lysines 381/382 and differentially coordinates p53-induced apoptosis
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  29. Identification of a Key Lysine Residue in Heat Shock Protein 90 Required for Azole and Echinocandin Resistance in Aspergillus fumigatus
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  30. 5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer’s Disease Phenotypes
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  32. Acetylation of αA-crystallin in the human lens: Effects on structure and chaperone function
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  33. Acetylated tau in Alzheimer's disease: An instigator of synaptic dysfunction underlying memory loss
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  34. Acetylation and deacetylation—novel factors in muscle wasting
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  37. Post-translational modification and conformational state of Heat Shock Protein 90 differentially affect binding of chemically diverse small molecule inhibitors
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  41. Tau Phosphorylation, Molecular Chaperones, and Ubiquitin E3 Ligase: Clinical Relevance in Alzheimer's Disease
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  45. Endoplasmic Reticulum-associated Degradation of Niemann-Pick C1
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  50. Contributions of Co-Chaperones and Post-Translational Modifications Towards Hsp90 Drug Sensitivity
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  51. Histone deacetylase inhibition as an alternative strategy against invasive aspergillosis
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  53. Class 1-Selective Histone Deacetylase (HDAC) Inhibitors Enhance HIV Latency Reversal while Preserving the Activity of HDAC Isoforms Necessary for Maximal HIV Gene Expression
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  54. Hsp90 middle domain phosphorylation initiates a complex conformational program to recruit the ATPase-stimulating cochaperone Aha1
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