FOXO3a Is Activated in Response to Hypoxic Stress and Inhibits HIF1-Induced Apoptosis via Regulation of CITED2

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2. Nipradilol and Timolol Induce Foxo3a and Peroxiredoxin 2 Expression and Protect Trabecular Meshwork Cells from Oxidative Stress
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3. The potential role and trend of HIF‑1α in intervertebral disc degeneration: Friend or foe? (Review)
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4. Forkhead box O3 (FoxO3) regulates kidney tubular autophagy following urinary tract obstruction
   Li, Ling, Zviti, Ronald, Ha, Catherine, Wang, Zhao V., Hill, Joseph A., Lin, Fangming · 2017 · Journal of Biological Chemistry
5. Syringaresinol protects against hypoxia/reoxygenation-induced cardiomyocytes injury and death by destabilization of HIF-1α in a FOXO3-dependent mechanism
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6. FOXO Transcription Factors Enforce Cell Cycle Checkpoints and Promote Survival of Hematopoietic Cells after DNA Damage
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7. CITED2 and NCOR2 in anti-oestrogen resistance and progression of breast cancer
   T van Agthoven, Anieta M. Sieuwerts, Jos Veldscholte, Marion E. Meijer‐van Gelder, Marcel Smid, Arend Brinkman, Alexander T. den Dekker, Ingrid M. Leroy, Wilfred F. J. van IJcken, Stefan Sleijfer et al. · 2009 · British Journal of Cancer
8. FoxO Proteins Mediate Hypoxic Induction of Connective Tissue Growth Factor in Endothelial Cells
   Jana Samarin, Julia Marina Wessel, Iwona Cicha, Sven Kroening, Christina Warnecke, Margarete Goppelt‐Struebe · 2009 · Journal of Biological Chemistry
9. The Regulation of the Autophagic Network and Its Implications for Human Disease
   Jing Hui Yang, Serena Carra, Wei‐Guo Zhu, Harm H. Kampinga · 2013 · International Journal of Biological Sciences
10. AKT signaling restrains tumor suppressive functions of FOXO transcription factors and GSK3 kinase in multiple myeloma
    Timon A. Bloedjes, Guus de Wilde, Chiel Maas, Eric Eldering, Richard J. Bende, Carel J.M. van Noesel, Steven T. Pals, Marcel Spaargaren, Jeroen E. J. Guikema · 2020 · Blood Advances
11. BNIP3L/NIX-mediated mitophagy alleviates passive stress-coping behaviors induced by tumor necrosis factor-α
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12. Knockdown of CITED2 using short‐hairpin RNA sensitizes cancer cells to cisplatin through stabilization of p53 and enhancement of p53‐dependent apoptosis
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13. Hypoxia Inducible Factor 1 Alpha Is Expressed in Germ Cells throughout the Murine Life Cycle
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14. PTPN12 promotes resistance to oxidative stress and supports tumorigenesis by regulating FOXO signaling
    Isaac S. Harris, Heiko Blaser, Juan Carlos Alvarez Moreno, Aislinn E. Treloar, Chiara Gorrini, Masato Sasaki, Jacqueline M. Mason, Christiane Brigitte Knobbe-Thomsen, Alessandro Rufini, Maxime Hallé et al. · 2013 · Oncogene
15. Erythropoietin, Forkhead Proteins, and Oxidative Injury: Biomarkers and Biology
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16. Arsenic trioxide plus PX-478 achieves effective treatment in pancreatic ductal adenocarcinoma
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17. Hypoxia-Activated PI3K/Akt Inhibits Oxidative Stress via the Regulation of Reactive Oxygen Species in Human Dental Pulp Cells
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18. FOXO3 Encodes a Carcinogen-Activated Transcription Factor Frequently Deleted in Early-Stage Lung Adenocarcinoma
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19. To breathe or not to breathe: Understanding how oxygen sensing contributes to age-related phenotypes
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20. Transcriptome analysis of the spalax hypoxia survival response includes suppression of apoptosis and tight control of angiogenesis
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21. Content-based microarray search using differential expression profiles
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22. Mechanisms controlling the anti-neoplastic functions of FoxO proteins
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23. Differentiation of Hodgkin lymphoma cells by reactive oxygen species and regulation by heme oxygenase‐1 through HIF‐1α
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24. Multifaceted roles of CCL20 (C-C motif chemokine ligand 20): mechanisms and communication networks in breast cancer progression
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25. mTOR Signaling Pathway and Gut Microbiota in Various Disorders: Mechanisms and Potential Drugs in Pharmacotherapy
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26. Regulation and Function of FoxO Transcription Factors in Normal and Cancer Stem Cells: What Have We Learned?
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27. Nuclear FOXO3 predicts adverse clinical outcome and promotes tumor angiogenesis in neuroblastoma
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28. Hypoxia enhances MUC1 expression in a lung adenocarcinoma cell line
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29. Development and Maintenance of Cancer Stem Cells under Chronic Inflammation
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30. Expression and prognosis of FOXO3a and HIF-1α in nasopharyngeal carcinoma
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31. Anoxia-responsive regulation of the FoxO transcription factors in freshwater turtles, Trachemys scripta elegans
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32. FOXO target gene CTDSP2 regulates cell cycle progression through Ras and p21Cip1/Waf1
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33. Regulation of Hypoxia-Induced Cell Death in Human Tenocytes
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34. Curcumin pretreatment protects against hypoxia/reoxgenation injury via improvement of mitochondrial function, destabilization of HIF-1α and activation of Epac1-Akt pathway in rat bone marrow mesenchymal stem cells
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35. Tolerance to Hypoxia Is Promoted by FOXO Regulation of the Innate Immunity Transcription Factor NF-κB/Relish in Drosophila
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36. Regulation of primordial follicle formation, dormancy, and activation in mice
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37. SHH-Dependent Knockout of HIF-1 Alpha Accelerates the Degenerative Process in Mouse Intervertebral Disc
    W-J. Wu, X.K. Zhang, X-F. Zheng, Yuehua Yang, S-D. Jiang, L-S. Jiang · 2013 · International Journal of Immunopathology and Pharmacology
38. Cited2 Gene Controls Pluripotency and Cardiomyocyte Differentiation of Murine Embryonic Stem Cells through Oct4 Gene
    Qiang Li, Diana L. Ramírez‐Bergeron, Sally L. Dunwoodie, Yu‐Chung Yang · 2012 · Journal of Biological Chemistry
39. Determination of hypoxia signature to predict prognosis and the tumor immune microenvironment in melanoma
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40. Transcriptional changes in the hypothalamus, pituitary, and mammary gland underlying decreased lactation performance in mice under heat stress
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41. Regulation of mitochondrial function by forkhead transcription factors
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42. Sod2 overexpression preserves myoblast mitochondrial mass and function, but not muscle mass with aging
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43. TGR5 deficiency aggravates hepatic ischemic/reperfusion injury via inhibiting SIRT3/FOXO3/HIF-1ɑ pathway
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44. A Replicative Self-Renewal Model for Long-Lived Plasma Cells: Questioning Irreversible Cell Cycle Exit
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45. CITED2 and the modulation of the hypoxic response in cancer
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46. CITED2-mediated human hematopoietic stem cell maintenance is critical for acute myeloid leukemia
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47. The interaction between Toll-like receptor 4 signaling pathway and hypoxia-inducible factor 1α in lung ischemia–reperfusion injury
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48. FOXO3a orchestrates glioma cell responses to starvation conditions and promotes hypoxia-induced cell death
    Daniel P. Brucker, Gabriele D. Maurer, Patrick N. Harter, Johannes Rieger, Jörg Steinbach · 2016 · International Journal of Oncology
49. Improved survival of mesenchymal stem cells by macrophage migration inhibitory factor
    Wenzheng Xia, Congying Xie, Miaomiao Jiang, Meng Hou · 2015 · Molecular and Cellular Biochemistry
50. Overexpression of Forkhead Box O3a and Its Association With Aggressive Phenotypes and Poor Prognosis in Human Hepatocellular Carcinoma
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51. FOXO3a elicits a pro-apoptotic transcription program and cellular response to human lung carcinogen nicotine-derived nitrosaminoketone (NNK)
    Daniel C. Blake, Oliver R. Mikse, Willard M. Freeman, Christopher R. Herzog · 2009 · Lung Cancer
52. CITED2 silencing sensitizes cancer cells to cisplatin by inhibiting p53 trans-activation and chromatin relaxation on the ERCC1 DNA repair gene
    Yu‐Chin Liu, Pu‐Yuan Chang, Chuck C.‐K. Chao · 2015 · Nucleic Acids Research
53. Inflammatory hypoxia induces syndecan‐2 expression through IL‐1b–mediated FOXO3a activation in colonic epithelia
    Sojoong Choi, Heesung Chung, Heejeong Hong, So Yeon Kim, Seong‐Eun Kim, Ju‐Young Seoh, Chang Mo Moon, Eun Gyeong Yang, Eok‐Soo Oh · 2016 · The FASEB Journal
54. SOX9 Knockdown-Mediated FOXO3 Downregulation Confers Neuroprotection Against Ischemic Brain Injury
    Yiming Deng, Gaoting Ma, Feng Gao, Xuan Sun, Lian Liu, Dapeng Mo, Ning Ma, Ligang Song, Xiaochuan Huo, Hongwei He et al. · 2021 · Frontiers in Cell and Developmental Biology
55. Gene expression network analysis reveals new transcriptional regulators as novel factors in human ischemic cardiomyopathy
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56. HIF‑1α affects trophoblastic apoptosis involved in the onset of preeclampsia by regulating FOXO3a under hypoxic conditions
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57. Cell death and survival signalling in the cardiovascular system
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58. Implantable Multifunctional Micro‐Oxygen Reservoir System for Promoting Vascular‐Osteogenesis via Remodeling Regenerative Microenvironment
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59. DMT1-Mutant Erythrocytes have Shortened Life Span, Accelerated Glycolysis and Increased Oxidative Stress
    Zuzana Zidova, Katarina Kapralova, Pavla Kořalková, Renata Mojzíková, Dalibor Doležal, Vladimír Divoký, Monika Horváthová · 2014 · Cellular Physiology and Biochemistry
60. Cited2, a Transcriptional Modulator Protein, Regulates Metabolism in Murine Embryonic Stem Cells
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61. Cited2 Is Required for the Maintenance of Glycolytic Metabolism in Adult Hematopoietic Stem Cells
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62. Methylseleninic acid elevates REDD1 and inhibits prostate cancer cell growth despite AKT activation and mTOR dysregulation in hypoxia
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63. Aβ induces PUMA activation: a new mechanism for Aβ-mediated neuronal apoptosis
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64. FoxO regulates expression of decidual protein induced by progesterone (DEPP) in human endothelial cells
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65. PRMT1 promotes hyperglycemia in a FoxO1-dependent manner, affecting glucose metabolism, during hypobaric hypoxia exposure, in rat model
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70. Transient Receptor Potential-Melastatin Channel Family Member 2: Friend or Foe.
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73. Role of CITED2 in stem cells and cancer (Review)
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74. Naked mole rats activate neuroprotective proteins during hypoxia
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78. Integrated expression analysis identifies transcription networks in mouse and human gastric neoplasia
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80. FOXOs Maintaining the Equilibrium for Better or for Worse
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