α4 Is an Essential Regulator of PP2A Phosphatase Activity
Cited by (160)
Items 101–160 of 160
- The Serine/Threonine Phosphatase PP4 Is Required for Pro-B Cell Development through Its Promotion of Immunoglobulin VDJ RecombinationYu‐Wen Su, Yaping Chen, Ming-yu Chen, Michael G. Reth, Tse‐Hua Tan · 2013 · PLoS ONE
- Homozygous knockout of eEF2K alleviates cognitive deficits in APP/PS1 Alzheimer’s disease model mice independent of brain amyloid β pathologyNicole P. Kasica, Xueyan Zhou, Hannah M. Jester, Caroline E. Holland, Alexey G. Ryazanov, Tom E. Forshaw, Cristina M. Furdui, Tao Ma · 2022 · Frontiers in Aging Neuroscience
- TIPRL1 and its ATM-dependent phosphorylation promote radiotherapy resistance in head and neck cancerCélie Cokelaere, Rüveyda Dok, Emanuela Elsa Cortesi, Peihua Zhao, Anna A. Sablina, Sandra Nuyts, Rita Derua, Veerle Janssens · 2023 · Cellular Oncology
- Coupling to short linear motifs creates versatile PME-1 activities in PP2A holoenzyme demethylation and inhibitionYitong Li, Vijaya Kumar Balakrishnan, Michael Rowse, Cheng-Guo Wu, Anastasia Phoebe Bravos, Vikash Kumar Yadav, Ylva Ivarsson, Stefan Strack, Irina Vasilievna Novikova, Yongna Xing · 2022 · eLife
- Essential Roles of the Tap42-Regulated Protein Phosphatase 2A (PP2A) Family in Wing Imaginal Disc Development of Drosophila melanogasterNing Wang, Hung‐Tat Leung, Matthew D. Mazalouskas, Guy R. Watkins, Rey J. Gomez, Brian E. Wadzinski · 2012 · PLoS ONE
- CaTip41 regulates protein phosphatase 2A activity, CaRad53 deactivation and the recovery of DNA damage-induced filamentation to yeast form inCandida albicansJinrong Feng, Yinong Duan, Sun Wei, Yongwei Qin, Zhong Zhuang, Dandan Zhu, Xiaolei Sun, Linghuo Jiang · 2016 · FEMS Yeast Research
- Emerging Roles of B56 Phosphorylation and Binding Motif in PP2A-B56 Holoenzyme Biological FunctionYanqiao Zhang, Haonan Jiang, Haimeng Yin, Xinyuan Zhao, Yali Zhang · 2024 · International Journal of Molecular Sciences
- Identification and Characterization of an Alternatively Spliced Isoform of the Human Protein Phosphatase 2Aα Catalytic SubunitDeivid Lucas dos Santos Migueleti, Juliana Helena Costa Smetana, Hugo Freire Nunes, Jörg Kobarg, Nilson Ivo Tonin Zanchin · 2011 · Journal of Biological Chemistry
- Competition between two phosphatases fine-tunes Hedgehog signalingMin Liu, Aiguo Liu, Jie Wang, Yansong Zhang, Yajuan Li, Ying Su, Alan Jian Zhu · 2020 · The Journal of Cell Biology
- XLOS-Observed Mutations of MID1 Bbox1 Domain Cause Domain UnfoldingKatharine M. Wright, Kuanlin Wu, Omotolani Babatunde, Haijuan Du, Michael Anthony Massiah · 2014 · PLoS ONE
- Novel involvement of RhebL1 in sphingosylphosphorylcholine-induced keratin phosphorylation and reorganization: Binding to and activation of AKT1Hyun Ji Kim, Hyun Jung Byun, Mi Kyung Park, Eun Ji Kim, Gyeoung-Jin Kang, Chang Hoon Lee · 2017 · Oncotarget
- Functional communication between PKC-targeted cardiac troponin I phosphorylation sitesSarah E. Lang, Tamara K. Stevenson, Tabea M. Schatz, Brandon J. Biesiadecki, Margaret V. Westfall · 2017 · Archives of Biochemistry and Biophysics
- Rules for PP2A-controlled phosphosignalling and drug responsesOtto Kauko, Susumu Y. Imanishi, Evgeny Kulesskiy, Teemu D. Laajala, Laxman Yetukuri, Anni Laine, Mikael Jumppanen, Pekka Haapaniemi, Luyao Ruan, Bhagwan Yadav et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Plasma immunoglobulin binding protein 1 as a predictor of development of lupus nephritisOh Chan Kwon, Eun‐Ju Lee, Ji Seon Oh, Seokchan Hong, Chang‐Keun Lee, Bin Yoo, Min‐Chan Park, Yong‐Gil Kim · 2020 · Lupus
- Comparative genomic analysis of high-altitude adaptation for Mongolia Mastiff, Tibetan Mastiff, and Canis LupusChunmei Cai, Yingzhong Yang, Qin Ga, Guocai Xu, Ri‐Li Ge, Feng Tang · 2022 · Genomics
- STRIPAK, a fundamental signaling hub of eukaryotic developmentUlrich Kück, Stefanie Pöggeler · 2024 · Microbiology and Molecular Biology Reviews
- Comparative transcriptome provides insights into the selection adaptation between wild and farmed foxesXiufeng Yang, Guangshuai Liu, Qi Wang, Xiaodong Gao, Tian Xia, Chao Zhao, Huashan Dou, Honghai Zhang · 2021 · Ecology and Evolution
- PME-1 sensitizes glioblastoma cells to oxidative stress-induced cell death by attenuating PP2A-B55α-mediated inactivation of MAPKAPK2-RIPK1 signalingLiesbeth Guffens, Rita Derua, Veerle Janssens · 2023 · Cell Death Discovery
- High expression of IGBP1 correlates with poor prognosis in esophageal squamous cell carcinomaSicong Jiang, Daojing Li, Zibin Liang, Yanhua Wang, Xiaofeng Pei, Jianjun Tang · 2019 · The International Journal of Biological Markers
- Potential roles of PP2A-Rac1 signaling axis in pancreatic β-cell dysfunction under metabolic stress: Progress and promiseAnjaneyulu Kowluru · 2020 · Biochemical Pharmacology
- Differential Expression of Genes for Ubiquitin Ligases in Medulloblastoma SubtypesJerry P. Vriend, ROBERT BRIAN TATE · 2019 · The Cerebellum
- Protein phosphatases and their targets: Comprehending the interactions in plant signaling pathwaysLokesh K. Saini, Malathi Bheri, Girdhar Kumar Pandey · 2023 · Advances in protein chemistry and structural biology
- YdjC chitooligosaccharide deacetylase homolog induces keratin reorganization in lung cancer cells: involvement of interaction between YDJC and CDC16Eun Ji Kim, Mi Kyung Park, Hyun Jung Byun, Gyeoung-Jin Kang, Lu Yu, Hyun Ji Kim, Jae Gal Shim, Ho Lee, Chang Hoon Lee · 2018 · Oncotarget
- Structural and functional observations of the P151L MID 1 mutation reveal alpha4 plays a significant role in X‐linked Opitz SyndromeKatharine M. Wright, Haijuan Du, Michael Anthony Massiah · 2017 · FEBS Journal
- Expression and mechanism of regulation of PP2A/Pr65 in ameloblastomaXiuqiu Gao, Guannan Wang, Yunkai Zhang, Ming Zhong · 2013 · The Surgeon
- Adaptation of protein phosphatases in Oryza sativa and Cucumis sativus to microcystinsXudong Ma, Yanfang Gu, Chanjuan Liang · 2022 · Environmental Science and Pollution Research
- Integrated analyzes identify CCT3 as a modulator to shape immunosuppressive tumor microenvironment in lung adenocarcinomaJunfeng Huang, Bingqi Hu, Ying Yang, Huanhuan Liu, Xingyu Fan, Jing Zhou, Liwen Chen · 2023 · BMC Cancer
- A Novel Interaction of the Catalytic Subunit of Protein Phosphatase 2A with the Adaptor Protein CIN85 Suppresses Phosphatase Activity and Facilitates Platelet Outside-in αIIbβ3 Integrin SignalingTanvir Khatlani, Subhashree Pradhan, Qi Da, Tanner S. Shaw, Vladimir L. Buchman, Miguel A. Crúz, K. Vinod Vijayan · 2016 · Journal of Biological Chemistry
- Alpha4 contributes to the dysfunction of the pancreatic beta cell under metabolic stressMirabela Hali, Brian E. Wadzinski, Anjaneyulu Kowluru · 2022 · Molecular and Cellular Endocrinology
- Protein Phosphatase 2A as a Therapeutic Target in Pulmonary DiseasesHoward K.Y. Yu, Sahil Zaveri, Zeeshan Sattar, Michael Schaible, Brais Perez Gandara, Anwar Uddin, Lucas R. McGarvey, Michael H. J. Ohlmeyer, Patrick M. Geraghty · 2023 · Medicina
- Promising Molecular Targets in Pharmacological Therapy for Neuronal Damage in Brain InjuryCristóbal de los Rı́os, Lucía Viejo, Victoria Jiménez, Natalia Hernández Juárez, Natália Alves Martins, Jesús Miguel Hernández-Guijo · 2023 · Antioxidants
- Effects of cerulein on keratin 8 phosphorylation and perinuclear reorganization in pancreatic cancer cells: Involvement of downregulation of protein phosphatase 2A and alpha4Mi Kyung Park, Chang Hoon Lee · 2015 · Environmental Toxicology
- The Phosphatase PP2A Links Glutamine to the Tumor Suppressor p53Dana M. Gwinn, Alejandro Sweet-Cordero · 2013 · Molecular Cell
- Identifying the SUMO1 modification of FAM122A leading to the degradation of PP2A-Cα by ubiquitin-proteasome systemFangzhi Fan, Junxing Zhao, Yali Liu, Hongfang Zhao, Lietao Weng, Qingqing Li, Guoqiang Chen, Ying Xu · 2018 · Biochemical and Biophysical Research Communications
- Alpha4‐overexpressing HL7702 cells can counteract microcystin‐LR effects on cytoskeletal structurePu Huang, Sha Wang, Dengpo Weng, Lihong Xu · 2018 · Environmental Toxicology
- TRPC1‐mediated Ca2+signaling enhances intestinal epithelial restitution by increasing α4 association with PP2Ac after woundingNavneeta Rathor, Hee Kyoung Chung, Jia‐Le Song, Shelley R. Wang, Jian‐Ying Wang, Jaladanki N. Rao · 2021 · Physiological Reports
- Adaptation to metabolic stress: Insights into a paradoxical QMichael A. Reid, Mei Kong · 2013 · Cell Cycle
- Template-driven scaffolding of SCFFBXO42 regulates PP2A degradationSébastien Coassolo, Nairie Michaelian, Timurs Maculins, Caleigh M. Azumaya, Tommy K. Cheung, Jianping Yin, Inna Zilberleyb, Kanika Bajaj Pahuja, Thomas P. Garner, Ted Lau et al. · 2026 · Nature
- B-box1 Domain of MID1 Interacts with the Ube2D1 E2 Enzyme Differently Than RING E3 LigasesAnupreet Kaur, Erin Gladu, Katharine M. Wright, Jessica Ann Webb, Michael Anthony Massiah · 2023 · Biochemistry
- Endogenous inhibitors of PP2A activate oncogenic and DNA damage response kinases in glioblastomaJohn Jacob, Shahid Mehdi Nimjee, J. Bradley Elder, Arnab Chakravarti, Kamalakannan Palanichamy · 2026 · Cancer Letters
- The PP2A/4/6 subfamily of phosphoprotein phosphatases regulates DAF-16 and confers resistance to environmental stress in postreproductive adult C. elegansRebecca S. Rivard, Julia M. Morris, Matthew J. Youngman · 2020 · PLoS ONE
- Regulation of cardiomyocyte DNA damage and cell death by the type 2A protein phosphatase regulatory protein alpha4Jonathan Cowan, Michael R. Longman, Andrew K. Snabaitis · 2021 · Scientific Reports
- Research progress on the relationship between the TOR signaling pathway regulator, epigenetics, and tumor developmentJiaen Sun, Minglei Yang, Weidi Zhao, Fajiu Wang, Liangwei Yang, Chuntao Tan, Tianjun Hu, Huangkai Zhu, Guofang Zhao · 2022 · Frontiers in Genetics
- TIPRL, a Potential Double-edge Molecule to be Targeted and Re-targeted Toward CancerJie Gao, Tiantian You, Jiao Liu, Lili Yang, Yan Liu, Yanyan Wang · 2024 · Cell Biochemistry and Biophysics
- Exploring the Human Protein Atlas (HPA) Portal for New Biomarkers in Urinary Bladder CarcinomaTina Bergström · 2010 · KTH Publication Database DiVA (KTH Royal Institute of Technology)
- Genetic regulation of autoantibodies in arthritis : lessons from mouse modelsBruno Raposo · 2012 · Figshare
- mTOR regulates Aurora A via enhancing protein stabilityFan Li · 2014 · IUScholarWorks (Indiana University)
- Novel protein phosphatase 2A complexes in skeletal muscle from obese insulin resistant human participantsDivyasri Damacharla · 2015 · Human Biology
- Role of Occludin in the Regulation of Epithelial Tight JunctionsBhargavi Manda · 2016
- Composition, regulation, and function of protein serine/threonine phosphatase.kinase signaling modulesMatthew D. Mazalouskas · 2014
- Characterization of the Interaction of Alpha4 Phosphoprotein with Novel Binding Partners: EDD E3 Ubiquitin Ligase and Poly(A)-Binding ProteinWilliam J. F. McDonald · 2011 · Library and Archives Canada (Government of Canada)
- Protein Phosphatase 2a Interactions In Islet And Human Skeletal Muscle In DiabetesDivyasri Damacharla · 2017 · Human Biology
- Protein Phosphatase 2a Function And Regulation In Insulin Resistant Human Skeletal Muscle CellsShukurat Sulaiman · 2017 · Human Biology
- Reversible Enzyme Phosphorylation as a Mechanism for Metabolic Adaptation to Dehydration in the Skeletal Muscle of the African Clawed Frog, Xenopus laevisChristie Childers · 2019
- Regulation of PP2Ac stability – discovery of a novel α4 monoubiquitination-dependent mechanism that is altered in Alzheimer’s diseaseGuy R. Watkins · 2012
- PhosphatasesJamal Khalife, Aline Fréville, Audrey Vandomme, Christine Pierrot · 2013 · Springer eBooks
- Caracterização da interação da proteína TIPRL com fosfatases tipo 2A em cultura de célulasAna Amélia Sanchez Iacia · 2021
- Additional file 1 of Integrated analyzes identify CCT3 as a modulator to shape immunosuppressive tumor microenvironment in lung adenocarcinomaHuang, Junfeng, Hu, Bingqi, Ying Yang, Liu, Huanhuan, Fan, Xingyu, Zhou, Jing, Chen, Liwen · 2023 · Figshare
- Medulloblastoma-Associated KBTBD4 Mutations Disrupt PP2A-A Orphan Quality ControlRegina Baur, Laura A. Hehl, Gajanan J. Sathe, Thomas Lunardi, Jonathan Schneider, Anna-Sophia Krebs, Juan Carlos Silva, Diane L. Haakonsen, Sebastian M. Waszak, Joachim Lingner et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- PhosphatasesJamal Khalife, Aline Fréville, Audrey Vandomme, Christine Pierrot · 2025 · Springer eBooks