α4 Is an Essential Regulator of PP2A Phosphatase Activity

Cited by (160)

Items 101–160 of 160

  1. The Serine/Threonine Phosphatase PP4 Is Required for Pro-B Cell Development through Its Promotion of Immunoglobulin VDJ Recombination
    Yu‐Wen Su, Yaping Chen, Ming-yu Chen, Michael G. Reth, Tse‐Hua Tan · 2013 · PLoS ONE
  2. Homozygous knockout of eEF2K alleviates cognitive deficits in APP/PS1 Alzheimer’s disease model mice independent of brain amyloid β pathology
    Nicole P. Kasica, Xueyan Zhou, Hannah M. Jester, Caroline E. Holland, Alexey G. Ryazanov, Tom E. Forshaw, Cristina M. Furdui, Tao Ma · 2022 · Frontiers in Aging Neuroscience
  3. TIPRL1 and its ATM-dependent phosphorylation promote radiotherapy resistance in head and neck cancer
    Célie Cokelaere, Rüveyda Dok, Emanuela Elsa Cortesi, Peihua Zhao, Anna A. Sablina, Sandra Nuyts, Rita Derua, Veerle Janssens · 2023 · Cellular Oncology
  4. Coupling to short linear motifs creates versatile PME-1 activities in PP2A holoenzyme demethylation and inhibition
    Yitong Li, Vijaya Kumar Balakrishnan, Michael Rowse, Cheng-Guo Wu, Anastasia Phoebe Bravos, Vikash Kumar Yadav, Ylva Ivarsson, Stefan Strack, Irina Vasilievna Novikova, Yongna Xing · 2022 · eLife
  5. Essential Roles of the Tap42-Regulated Protein Phosphatase 2A (PP2A) Family in Wing Imaginal Disc Development of Drosophila melanogaster
    Ning Wang, Hung‐Tat Leung, Matthew D. Mazalouskas, Guy R. Watkins, Rey J. Gomez, Brian E. Wadzinski · 2012 · PLoS ONE
  6. CaTip41 regulates protein phosphatase 2A activity, CaRad53 deactivation and the recovery of DNA damage-induced filamentation to yeast form inCandida albicans
    Jinrong Feng, Yinong Duan, Sun Wei, Yongwei Qin, Zhong Zhuang, Dandan Zhu, Xiaolei Sun, Linghuo Jiang · 2016 · FEMS Yeast Research
  7. Emerging Roles of B56 Phosphorylation and Binding Motif in PP2A-B56 Holoenzyme Biological Function
    Yanqiao Zhang, Haonan Jiang, Haimeng Yin, Xinyuan Zhao, Yali Zhang · 2024 · International Journal of Molecular Sciences
  8. Identification and Characterization of an Alternatively Spliced Isoform of the Human Protein Phosphatase 2Aα Catalytic Subunit
    Deivid Lucas dos Santos Migueleti, Juliana Helena Costa Smetana, Hugo Freire Nunes, Jörg Kobarg, Nilson Ivo Tonin Zanchin · 2011 · Journal of Biological Chemistry
  9. Competition between two phosphatases fine-tunes Hedgehog signaling
    Min Liu, Aiguo Liu, Jie Wang, Yansong Zhang, Yajuan Li, Ying Su, Alan Jian Zhu · 2020 · The Journal of Cell Biology
  10. XLOS-Observed Mutations of MID1 Bbox1 Domain Cause Domain Unfolding
    Katharine M. Wright, Kuanlin Wu, Omotolani Babatunde, Haijuan Du, Michael Anthony Massiah · 2014 · PLoS ONE
  11. Novel involvement of RhebL1 in sphingosylphosphorylcholine-induced keratin phosphorylation and reorganization: Binding to and activation of AKT1
    Hyun Ji Kim, Hyun Jung Byun, Mi Kyung Park, Eun Ji Kim, Gyeoung-Jin Kang, Chang Hoon Lee · 2017 · Oncotarget
  12. Functional communication between PKC-targeted cardiac troponin I phosphorylation sites
    Sarah E. Lang, Tamara K. Stevenson, Tabea M. Schatz, Brandon J. Biesiadecki, Margaret V. Westfall · 2017 · Archives of Biochemistry and Biophysics
  13. Rules for PP2A-controlled phosphosignalling and drug responses
    Otto Kauko, Susumu Y. Imanishi, Evgeny Kulesskiy, Teemu D. Laajala, Laxman Yetukuri, Anni Laine, Mikael Jumppanen, Pekka Haapaniemi, Luyao Ruan, Bhagwan Yadav et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  14. Plasma immunoglobulin binding protein 1 as a predictor of development of lupus nephritis
    Oh Chan Kwon, Eun‐Ju Lee, Ji Seon Oh, Seokchan Hong, Chang‐Keun Lee, Bin Yoo, Min‐Chan Park, Yong‐Gil Kim · 2020 · Lupus
  15. Comparative genomic analysis of high-altitude adaptation for Mongolia Mastiff, Tibetan Mastiff, and Canis Lupus
    Chunmei Cai, Yingzhong Yang, Qin Ga, Guocai Xu, Ri‐Li Ge, Feng Tang · 2022 · Genomics
  16. STRIPAK, a fundamental signaling hub of eukaryotic development
    Ulrich Kück, Stefanie Pöggeler · 2024 · Microbiology and Molecular Biology Reviews
  17. Comparative transcriptome provides insights into the selection adaptation between wild and farmed foxes
    Xiufeng Yang, Guangshuai Liu, Qi Wang, Xiaodong Gao, Tian Xia, Chao Zhao, Huashan Dou, Honghai Zhang · 2021 · Ecology and Evolution
  18. PME-1 sensitizes glioblastoma cells to oxidative stress-induced cell death by attenuating PP2A-B55α-mediated inactivation of MAPKAPK2-RIPK1 signaling
    Liesbeth Guffens, Rita Derua, Veerle Janssens · 2023 · Cell Death Discovery
  19. High expression of IGBP1 correlates with poor prognosis in esophageal squamous cell carcinoma
    Sicong Jiang, Daojing Li, Zibin Liang, Yanhua Wang, Xiaofeng Pei, Jianjun Tang · 2019 · The International Journal of Biological Markers
  20. Potential roles of PP2A-Rac1 signaling axis in pancreatic β-cell dysfunction under metabolic stress: Progress and promise
    Anjaneyulu Kowluru · 2020 · Biochemical Pharmacology
  21. Differential Expression of Genes for Ubiquitin Ligases in Medulloblastoma Subtypes
    Jerry P. Vriend, ROBERT BRIAN TATE · 2019 · The Cerebellum
  22. Protein phosphatases and their targets: Comprehending the interactions in plant signaling pathways
    Lokesh K. Saini, Malathi Bheri, Girdhar Kumar Pandey · 2023 · Advances in protein chemistry and structural biology
  23. YdjC chitooligosaccharide deacetylase homolog induces keratin reorganization in lung cancer cells: involvement of interaction between YDJC and CDC16
    Eun Ji Kim, Mi Kyung Park, Hyun Jung Byun, Gyeoung-Jin Kang, Lu Yu, Hyun Ji Kim, Jae Gal Shim, Ho Lee, Chang Hoon Lee · 2018 · Oncotarget
  24. Structural and functional observations of the P151L MID 1 mutation reveal alpha4 plays a significant role in X‐linked Opitz Syndrome
    Katharine M. Wright, Haijuan Du, Michael Anthony Massiah · 2017 · FEBS Journal
  25. Expression and mechanism of regulation of PP2A/Pr65 in ameloblastoma
    Xiuqiu Gao, Guannan Wang, Yunkai Zhang, Ming Zhong · 2013 · The Surgeon
  26. Adaptation of protein phosphatases in Oryza sativa and Cucumis sativus to microcystins
    Xudong Ma, Yanfang Gu, Chanjuan Liang · 2022 · Environmental Science and Pollution Research
  27. Integrated analyzes identify CCT3 as a modulator to shape immunosuppressive tumor microenvironment in lung adenocarcinoma
    Junfeng Huang, Bingqi Hu, Ying Yang, Huanhuan Liu, Xingyu Fan, Jing Zhou, Liwen Chen · 2023 · BMC Cancer
  28. A Novel Interaction of the Catalytic Subunit of Protein Phosphatase 2A with the Adaptor Protein CIN85 Suppresses Phosphatase Activity and Facilitates Platelet Outside-in αIIbβ3 Integrin Signaling
    Tanvir Khatlani, Subhashree Pradhan, Qi Da, Tanner S. Shaw, Vladimir L. Buchman, Miguel A. Crúz, K. Vinod Vijayan · 2016 · Journal of Biological Chemistry
  29. Alpha4 contributes to the dysfunction of the pancreatic beta cell under metabolic stress
    Mirabela Hali, Brian E. Wadzinski, Anjaneyulu Kowluru · 2022 · Molecular and Cellular Endocrinology
  30. Protein Phosphatase 2A as a Therapeutic Target in Pulmonary Diseases
    Howard K.Y. Yu, Sahil Zaveri, Zeeshan Sattar, Michael Schaible, Brais Perez Gandara, Anwar Uddin, Lucas R. McGarvey, Michael H. J. Ohlmeyer, Patrick M. Geraghty · 2023 · Medicina
  31. Promising Molecular Targets in Pharmacological Therapy for Neuronal Damage in Brain Injury
    Cristóbal de los Rı́os, Lucía Viejo, Victoria Jiménez, Natalia Hernández Juárez, Natália Alves Martins, Jesús Miguel Hernández-Guijo · 2023 · Antioxidants
  32. Effects of cerulein on keratin 8 phosphorylation and perinuclear reorganization in pancreatic cancer cells: Involvement of downregulation of protein phosphatase 2A and alpha4
    Mi Kyung Park, Chang Hoon Lee · 2015 · Environmental Toxicology
  33. The Phosphatase PP2A Links Glutamine to the Tumor Suppressor p53
    Dana M. Gwinn, Alejandro Sweet-Cordero · 2013 · Molecular Cell
  34. Identifying the SUMO1 modification of FAM122A leading to the degradation of PP2A-Cα by ubiquitin-proteasome system
    Fangzhi Fan, Junxing Zhao, Yali Liu, Hongfang Zhao, Lietao Weng, Qingqing Li, Guoqiang Chen, Ying Xu · 2018 · Biochemical and Biophysical Research Communications
  35. Alpha4‐overexpressing HL7702 cells can counteract microcystin‐LR effects on cytoskeletal structure
    Pu Huang, Sha Wang, Dengpo Weng, Lihong Xu · 2018 · Environmental Toxicology
  36. TRPC1‐mediated Ca2+signaling enhances intestinal epithelial restitution by increasing α4 association with PP2Ac after wounding
    Navneeta Rathor, Hee Kyoung Chung, Jia‐Le Song, Shelley R. Wang, Jian‐Ying Wang, Jaladanki N. Rao · 2021 · Physiological Reports
  37. Adaptation to metabolic stress: Insights into a paradoxical Q
    Michael A. Reid, Mei Kong · 2013 · Cell Cycle
  38. Template-driven scaffolding of SCFFBXO42 regulates PP2A degradation
    Sébastien Coassolo, Nairie Michaelian, Timurs Maculins, Caleigh M. Azumaya, Tommy K. Cheung, Jianping Yin, Inna Zilberleyb, Kanika Bajaj Pahuja, Thomas P. Garner, Ted Lau et al. · 2026 · Nature
  39. B-box1 Domain of MID1 Interacts with the Ube2D1 E2 Enzyme Differently Than RING E3 Ligases
    Anupreet Kaur, Erin Gladu, Katharine M. Wright, Jessica Ann Webb, Michael Anthony Massiah · 2023 · Biochemistry
  40. Endogenous inhibitors of PP2A activate oncogenic and DNA damage response kinases in glioblastoma
    John Jacob, Shahid Mehdi Nimjee, J. Bradley Elder, Arnab Chakravarti, Kamalakannan Palanichamy · 2026 · Cancer Letters
  41. The PP2A/4/6 subfamily of phosphoprotein phosphatases regulates DAF-16 and confers resistance to environmental stress in postreproductive adult C. elegans
    Rebecca S. Rivard, Julia M. Morris, Matthew J. Youngman · 2020 · PLoS ONE
  42. Regulation of cardiomyocyte DNA damage and cell death by the type 2A protein phosphatase regulatory protein alpha4
    Jonathan Cowan, Michael R. Longman, Andrew K. Snabaitis · 2021 · Scientific Reports
  43. Research progress on the relationship between the TOR signaling pathway regulator, epigenetics, and tumor development
    Jiaen Sun, Minglei Yang, Weidi Zhao, Fajiu Wang, Liangwei Yang, Chuntao Tan, Tianjun Hu, Huangkai Zhu, Guofang Zhao · 2022 · Frontiers in Genetics
  44. TIPRL, a Potential Double-edge Molecule to be Targeted and Re-targeted Toward Cancer
    Jie Gao, Tiantian You, Jiao Liu, Lili Yang, Yan Liu, Yanyan Wang · 2024 · Cell Biochemistry and Biophysics
  45. Exploring the Human Protein Atlas (HPA) Portal for New Biomarkers in Urinary Bladder Carcinoma
    Tina Bergström · 2010 · KTH Publication Database DiVA (KTH Royal Institute of Technology)
  46. Genetic regulation of autoantibodies in arthritis : lessons from mouse models
    Bruno Raposo · 2012 · Figshare
  47. mTOR regulates Aurora A via enhancing protein stability
    Fan Li · 2014 · IUScholarWorks (Indiana University)
  48. Novel protein phosphatase 2A complexes in skeletal muscle from obese insulin resistant human participants
    Divyasri Damacharla · 2015 · Human Biology
  49. Role of Occludin in the Regulation of Epithelial Tight Junctions
    Bhargavi Manda · 2016
  50. Composition, regulation, and function of protein serine/threonine phosphatase.kinase signaling modules
    Matthew D. Mazalouskas · 2014
  51. Characterization of the Interaction of Alpha4 Phosphoprotein with Novel Binding Partners: EDD E3 Ubiquitin Ligase and Poly(A)-Binding Protein
    William J. F. McDonald · 2011 · Library and Archives Canada (Government of Canada)
  52. Protein Phosphatase 2a Interactions In Islet And Human Skeletal Muscle In Diabetes
    Divyasri Damacharla · 2017 · Human Biology
  53. Protein Phosphatase 2a Function And Regulation In Insulin Resistant Human Skeletal Muscle Cells
    Shukurat Sulaiman · 2017 · Human Biology
  54. Reversible Enzyme Phosphorylation as a Mechanism for Metabolic Adaptation to Dehydration in the Skeletal Muscle of the African Clawed Frog, Xenopus laevis
    Christie Childers · 2019
  55. Regulation of PP2Ac stability – discovery of a novel α4 monoubiquitination-dependent mechanism that is altered in Alzheimer’s disease
    Guy R. Watkins · 2012
  56. Phosphatases
    Jamal Khalife, Aline Fréville, Audrey Vandomme, Christine Pierrot · 2013 · Springer eBooks
  57. Caracterização da interação da proteína TIPRL com fosfatases tipo 2A em cultura de células
    Ana Amélia Sanchez Iacia · 2021
  58. Additional file 1 of Integrated analyzes identify CCT3 as a modulator to shape immunosuppressive tumor microenvironment in lung adenocarcinoma
    Huang, Junfeng, Hu, Bingqi, Ying Yang, Liu, Huanhuan, Fan, Xingyu, Zhou, Jing, Chen, Liwen · 2023 · Figshare
  59. Medulloblastoma-Associated KBTBD4 Mutations Disrupt PP2A-A Orphan Quality Control
    Regina Baur, Laura A. Hehl, Gajanan J. Sathe, Thomas Lunardi, Jonathan Schneider, Anna-Sophia Krebs, Juan Carlos Silva, Diane L. Haakonsen, Sebastian M. Waszak, Joachim Lingner et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  60. Phosphatases
    Jamal Khalife, Aline Fréville, Audrey Vandomme, Christine Pierrot · 2025 · Springer eBooks