Lindsten, Tullia

Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

Wei, M. C., Zong, W.-X., Cheng, E. H.-Y., Lindsten, T., Panoutsakopoulou, V., Ross, A. J., Roth, K. A., MacGregor, G. R., Thompson, C. B., & Korsmeyer, S. J. (2001) · Science

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 3,988

The Combined Functions of Proapoptotic Bcl-2 Family Members Bak and Bax Are Essential for Normal Development of Multiple Tissues

Lindsten, T., Ross, A. J., King, A., Zong, W.-X., Rathmell, J. C., Shiels, H. A., Ulrich, E., Waymire, K. G., Mahar, P., Frauwirth, K., et al. (2000) · Molecular Cell

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 1,489

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

Lum, J. J., Bauer, D. E., Kong, M., Harris, M. H., Li, C., Lindsten, T., & Thompson, C. B. (2005) · Cell

Autophagy in Disease and TherapyCell death mechanisms and regulation

Cited by 1,487

Control of Effector CD8 + T Cell Function by the Transcription Factor Eomesodermin

Pearce, E. L., Mullen, A. C., Martins, G. A., Krawczyk, C. M., Hutchins, A. S., Zediak, V. P., Banica, M., DiCioccio, C. B., Gross, D. A., Mao, C.-A., et al. (2003) · Science

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 1,014

Serine Catabolism Regulates Mitochondrial Redox Control during Hypoxia

Ye, J., Fan, J., Venneti, S., Wan, Y.-W., Pawel, B. R., Zhang, J., Finley, L. W. S., Lu, C., Lindsten, T., Cross, J. R., et al. (2014) · Cancer Discovery

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 452

Bax regulates primary necrosis through mitochondrial dynamics

Whelan, R. S., Konstantinidis, K., Wei, A.-C., Chen, Y., Reyna, D. E., Jha, S., Yang, Y., Calvert, J. W., Lindsten, T., Thompson, C. B., et al. (2012) · Proceedings of the National Academy of Sciences

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 290

CD28 ligation in T-cell activation: evidence for two signal transduction pathways.

Ledbetter, J., Imboden, J., Schieven, G., Grosmaire, L., Rabinovitch, P., Lindsten, T., Thompson, C., & June, C. (1990) · Blood

T-cell and B-cell ImmunologySignaling Pathways in Disease

Cited by 170

α4 Is an Essential Regulator of PP2A Phosphatase Activity

Kong, M., Ditsworth, D., Lindsten, T., & Thompson, C. B. (2009) · Molecular Cell

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

Cited by 162

The PP2A-Associated Protein α4 Is an Essential Inhibitor of Apoptosis

Kong, M., Fox, C. J., Mu, J., Solt, L., Xu, A., Cinalli, R. M., Birnbaum, M. J., Lindsten, T., & Thompson, C. B. (2004) · Science

Cell death mechanisms and regulationProtein Tyrosine Phosphatases

Cited by 149

The Proapoptotic Factors Bax and Bak Regulate T Cell Proliferation through Control of Endoplasmic Reticulum Ca2+ Homeostasis

Jones, R. G., Bui, T., White, C., Madesh, M., Krawczyk, C. M., Lindsten, T., Hawkins, B. J., Kubek, S., Frauwirth, K. A., Wang, Y. L., et al. (2007) · Immunity

Cell death mechanisms and regulationIon Channels and Receptors

Cited by 109

The proapoptotic activities of Bax and Bak limit the size of the neural stem cell pool

Lindsten, T., Golden, J. A., Zong, W.-X., Minarcik, J., Harris, M. H., & Thompson, C. B. (2003) · The Journal of Neuroscience

Cell death mechanisms and regulationNeurogenesis and neuroplasticity mechanisms

Cited by 107

The PP2A-associated Protein α4 Plays a Critical Role in the Regulation of Cell Spreading and Migration

Kong, M., Bui, T. V., Ditsworth, D., Gruber, J. J., Goncharov, D., Krymskaya, V. P., Lindsten, T., & Thompson, C. B. (2007) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

Cited by 43

Maintenance of the relative proportion of oligodendrocytes to axons even in the absence of BAX and BAK

Kawai, K., Itoh, T., Itoh, A., Horiuchi, M., Wakayama, K., Bannerman, P., Garbern, J. Y., Pleasure, D., & Lindsten, T. (2009) · European Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsCell death mechanisms and regulation

Cited by 21