SIRT1 Regulates UV-Induced DNA Repair through Deacetylating XPA

hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase

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Negative Control of p53 by Sir2α Promotes Cell Survival under Stress

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UV-induced DNA damage and repair: a review

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Sirtuins in mammals: insights into their biological function

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Mammalian SIRT1 Represses Forkhead Transcription Factors

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Duration of Nuclear NF-κB Action Regulated by Reversible Acetylation

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Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

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Involvement of the TIP60 Histone Acetylase Complex in DNA Repair and Apoptosis

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Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin.

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SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging

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Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF‐κB

Chen, L., Mu, Y., & Greene, W. C. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf660 · Cited by 827

Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice

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A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM

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The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth.

Firestein, R., Blander, G., Michan, S., Oberdoerffer, P., Ogino, S., Campbell, J., Bhimavarapu, A., Luikenhuis, S., de Cabo, R., Fuchs, C., et al. (2008) · PLoS ONE · doi:10.1371/journal.pone.0002020 · Cited by 588

DBC1 is a negative regulator of SIRT1

Kim, J., Chen, J., & Lou, Z. (2008) · Nature · doi:10.1038/nature06500 · Cited by 513

Negative regulation of the deacetylase SIRT1 by DBC1

Zhao, W., Kruse, J.-P., Tang, Y., Jung, S. Y., Qin, J., & Gu, W. J. (2008) · Nature · doi:10.1038/nature06515 · Cited by 475

Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage

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How does SIRT1 affect metabolism, senescence and cancer?

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Sirt1 inhibitor, Sirtinol, induces senescence-like growth arrest with attenuated Ras–MAPK signaling in human cancer cells

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The eukaryotic nucleotide excision repair pathway

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Interplay among BRCA1, SIRT1, and Survivin during BRCA1-Associated Tumorigenesis

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SIRT1 promotes DNA repair activity and deacetylation of Ku70

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SIRT1, Is It a Tumor Promoter or Tumor Suppressor?

Deng, C. (2009) · International Journal of Biological Sciences · doi:10.7150/ijbs.5.147 · Cited by 325

SIRT1 Regulates the Function of the Nijmegen Breakage Syndrome Protein

Yuan, Z., Zhang, X. M., Sengupta, N., Lane, W. S., & Seto, E. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.05.029 · Cited by 277

Activation of Stat3 Sequence-specific DNA Binding and Transcription by p300/CREB-binding Protein-mediated Acetylation

Wang, R., Cherukuri, P., & Luo, J. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m413930200 · Cited by 275

Regulation of WRN Protein Cellular Localization and Enzymatic Activities by SIRT1-mediated Deacetylation

Li, K., Casta, A., Wang, R., Lozada, E., Fan, W., Kane, S. E., Ge, Q., Gu, W. J., Orren, D. K., & Luo, J. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m709707200 · Cited by 177

DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of Sir3p

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SIRT1: roles in aging and cancer

Kim, E.-J., & Um, S. (2008) · BMB Reports · doi:10.5483/bmbrep.2008.41.11.751 · Cited by 91

Phosphorylation of Nucleotide Excision Repair Factor Xeroderma Pigmentosum Group A by Ataxia Telangiectasia Mutated and Rad3-Related–Dependent Checkpoint Pathway Promotes Cell Survival in Response to UV Irradiation

Wu, X., Shell, S. M., Yang, Z., & Zou, Y. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-3403 · Cited by 87 · cited 2×

Checkpoint Kinase ATR Promotes Nucleotide Excision Repair of UV-induced DNA Damage via Physical Interaction with Xeroderma Pigmentosum Group A

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A Functional Link Between SIRT1 Deacetylase and NBS1 in DNA Damage Response

Yuan, Z., & Seto, E. (2007) · Cell Cycle · doi:10.4161/cc.6.23.5026 · Cited by 77

RecQ4 Facilitates UV Light-induced DNA Damage Repair through Interaction with Nucleotide Excision Repair Factor Xeroderma Pigmentosum Group A (XPA)

Fan, W., & Luo, J. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m801928200 · Cited by 74

Quantitation and Visualization of Ultraviolet‐Induced DNA Damage Using Specific Antibodies: Application to Pigment Cell Biology

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Sirtuins (histone deacetylases III) in the cellular response to DNA damage—Facts and hypotheses

Kruszewski, M. K., & Szumiel, I. (2005) · DNA repair · doi:10.1016/j.dnarep.2005.06.013 · Cited by 65

Human Xeroderma Pigmentosum Group A Protein Interacts with Human Replication Protein A and Inhibits DNA Replication

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Acetylation of MyoD by p300 Requires More Than Its Histone Acetyltransferase Domain

Polesskaya, A., & Harel‐Bellan, A. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m106501200 · Cited by 42

Domains in the XPA protein important in its role as a processivity factor

Bartels, C. L., & Lambert, M. W. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.02.125 · Cited by 27

NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

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Functions and mechanisms of non-histone protein acetylation

Narita, T., Weinert, B. T., & Choudhary, C. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-018-0081-3 · Cited by 1,232

Nucleotide Excision Repair in EukaryotesPreprint

Schärer, O. D. (2013) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a012609 · Cited by 863

The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance

Bouwman, P., & Jonkers, J. (2012) · Nature Reviews Cancer · doi:10.1038/nrc3342 · Cited by 615

Oxidative Damage Targets Complexes Containing DNA Methyltransferases, SIRT1, and Polycomb Members to Promoter CpG Islands

O’Hagan, H. M., Wang, W., Sen, S., Shields, C. E. D., Lee, S. S., Zhang, Y. W., Clements, E. G., Cai, Y., Neste, L. V., Easwaran, H., et al. (2011) · Cancer Cell · doi:10.1016/j.ccr.2011.09.012 · Cited by 593

Regulation of the Functional Properties of Xeroderma Pigmentosum Complementation Group A (XPA) Protein through Lysine Acetylation

Njeri, C. W., Kaur, J., Turchi, J. J., & Balakrishnan, L. (2017) · The FASEB Journal · doi:10.1096/fasebj.31.1_supplement.lb56

Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C

Ming, M., Shea, C. R., Guo, X., Li, X., Soltani, K., Han, W., & He, Y.-Y. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1010377108 · Cited by 148

Expression of Concern: Sirtuin 1-mediated deacetylation of XPA DNA repair protein enhances its interaction with ATR protein and promotes cAMP-induced DNA repair of UV damage.

(2020) · Journal of Biological Chemistry · doi:10.1074/jbc.ec120.015927

Phosphorylation of Nucleotide Excision Repair Factor Xeroderma Pigmentosum Group A by Ataxia Telangiectasia Mutated and Rad3-Related–Dependent Checkpoint Pathway Promotes Cell Survival in Response to UV Irradiation

Wu, X., Shell, S. M., Yang, Z., & Zou, Y. (2006) · Cancer Research · doi:10.1158/0008-5472.can-05-3403 · Cited by 87

NDR1 modulates the UV-induced DNA-damage checkpoint and nucleotide excision repair

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