SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome

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2. The antiviral sirtuin 3 bridges protein acetylation to mitochondrial integrity and metabolism during human cytomegalovirus infection
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3. NIPSNAP protein family emerges as a sensor of mitochondrial health
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4. Sirt3 Pharmacologically Promotes Insulin Sensitivity through PI3/AKT/mTOR and Their Downstream Pathway in Adipocytes
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5. CREBH alleviates mitochondrial oxidative stress through SIRT3 mediating deacetylation of MnSOD and suppression of Nlrp3 inflammasome in NASH
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6. Mild endothelial dysfunction in Sirt3 knockout mice fed a high-cholesterol diet: protective role of a novel C/EBP-β-dependent feedback regulation of SOD2
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7. Metformin Therapy for Pulmonary Hypertension Associated with Heart Failure with Preserved Ejection Fraction versus Pulmonary Arterial Hypertension
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8. Hyperacetylation of Cardiac Mitochondrial Proteins Is Associated with Metabolic Impairment and Sirtuin Downregulation after Chronic Total Body Irradiation of ApoE -/- Mice
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9. NAD+ Metabolism as an Emerging Therapeutic Target for Cardiovascular Diseases Associated With Sudden Cardiac Death
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10. Nutrigenomics and Nutrigenetics in Metabolic- (Dysfunction) Associated Fatty Liver Disease: Novel Insights and Future Perspectives
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11. Resveratrol Prevents Right Ventricle Dysfunction, Calcium Mishandling, and Energetic Failure via SIRT3 Stimulation in Pulmonary Arterial Hypertension
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12. SZC-6, a small-molecule activator of SIRT3, attenuates cardiac hypertrophy in mice
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13. Genetic dissection of blood lipid traits by integrating genome-wide association study and gene expression profiling in a porcine model
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14. Sirtuins in Hematological Aging and Malignancy
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15. SIRTain regulators of premature senescence and accelerated aging
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16. Mitochondrial lysine deacetylation promotes energy metabolism and calcium signaling in insulin‐secreting cells
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17. Docking and binding free energy calculations of sirtuin inhibitors
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18. Role of Histone Deacetylases in Skeletal Muscle Physiology and Systemic Energy Homeostasis: Implications for Metabolic Diseases and Therapy
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19. Resveratrol Stimulates Cortisol Biosynthesis by Activating SIRT-Dependent Deacetylation of P450scc
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20. Protective Effects of PGC-1α Against Lead-Induced Oxidative Stress and Energy Metabolism Dysfunction in Testis Sertoli Cells
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21. The plasticizer BBP selectively inhibits epigenetic regulator sirtuin during differentiation of C3H10T1/2 stem cell line
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22. Post‐translational modifications of proteins in cardiovascular diseases examined by proteomic approaches
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23. SIRT3 Deficiency Promotes Lung Endothelial Pyroptosis Through Impairing Mitophagy to Activate NLRP3 Inflammasome During Sepsis-Induced Acute Lung Injury
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24. New Perspectives on Postmenopausal Osteoporosis: Mechanisms and Potential Therapeutic Strategies of Sirtuins and Oxidative Stress
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25. Obesity, cancer and acetyl-CoA metabolism
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26. Low-Dose Pesticide Mixture Induces Accelerated Mesenchymal Stem Cell Aging In Vitro
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27. Antioxidant and Cardioprotective Effects of EPA on Early Low-Severity Sepsis through UCP3 and SIRT3 Upholding of the Mitochondrial Redox Potential
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28. Metabolic syndrome exacerbates amyloid pathology in a comorbid Alzheimer's mouse model
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29. Sirt5 Deficiency Causes Posttranslational Protein Malonylation and Dysregulated Cellular Metabolism in Chondrocytes Under Obesity Conditions
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30. Protein lysine acetylation and its role in different human pathologies: a proteomic approach
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31. Citicoline ameliorates arsenic-induced hepatotoxicity and diabetes in mice by overexpression of VAMP2, PPAR-γ, As3MT, and SIRT3
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32. Sirtuin biology and relevance to diabetes treatment
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33. Effects of Moringa oleifera Leaves Extract on High Glucose-Induced Metabolic Changes in HepG2 Cells
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34. Histone deacetylase 11 as a key regulator of metabolism and obesity
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35. SIRT3 Ablation Deteriorates Obesity-Related Cardiac Remodeling by Modulating ROS-NF-κB-MCP-1 Signaling Pathway
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36. Transcriptomic and epigenomic landscapes of Alzheimer's disease evidence mitochondrial-related pathways
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37. Sirt3 mediates the benefits of exercise on bone in aged mice
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38. Resistin impairs mitochondrial homeostasis via cyclase-associated protein 1-mediated fission, leading to obesity-induced metabolic diseases
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39. Dendropanoxide Alleviates Thioacetamide-induced Hepatic Fibrosis via Inhibition of ROS Production and Inflammation in BALB/C Mice
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40. Cyclophilin D-mediated Mitochondrial Permeability Transition Regulates Mitochondrial Function
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41. The role of lysine acetylation in metabolic sensing and proteostasis
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42. Tricarboxylic acid cycle activity suppresses acetylation of mitochondrial proteins during early embryonic development in Caenorhabditis elegans
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43. PPARα agonist fenofibrate attenuates iron-induced liver injury in mice by modulating the Sirt3 and β-catenin signaling
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44. Post-translational lysine ac(et)ylation in health, ageing and disease
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45. Dihydromyricetin Protects Intestinal Barrier Integrity by Promoting IL-22 Expression in ILC3s through the AMPK/SIRT3/STAT3 Signaling Pathway
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46. Mitochondrial SIRT3: A New Potential Therapeutic Target for Metabolic Syndrome
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47. Skeletal Muscle SIRT3 Deficiency Contributes to Pulmonary Vascular Remodeling in Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction
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48. Mitochondrial Acetylation and Genetic Models of Parkinson's Disease
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49. SIRT3 as a Regulator of Non-alcoholic Fatty Liver Disease
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50. Role of histone deacetylase Sirt3 in the development and regression of atherosclerosis
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51. HSP60 reduction protects against diet-induced obesity by modulating energy metabolism in adipose tissue
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52. MCU-Dependent mROS Generation Regulates Cell Metabolism and Cell Death Modulated by the AMPK/PGC-1α/SIRT3 Signaling Pathway
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53. Genetic and Functional Sequence Variants of the SIRT3 Gene Promoter in Myocardial Infarction
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54. Regulation of SIRT3/FOXO1 Signaling Pathway in Rats with Non-alcoholic Steatohepatitis by Salvianolic Acid B
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55. Effect of the Leptin Receptor Q223R Polymorphism on the Host Transcriptome following Infection with Entamoeba histolytica
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56. Re-Evaluating the Oxidative Phenotype: Can Endurance Exercise Save the Western World?
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57. Effects of Lipotoxicity in Brain Microvascular Endothelial Cells During Sirt3 Deficiency-Potential Role in Comorbid Alzheimer’s Disease
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58. MD2 deficiency prevents high‐fat diet‐induced AMPK suppression and lipid accumulation through regulating TBK1 in non‐alcoholic fatty liver disease
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59. Effect of the Leptin Receptor Q223R Polymorphism on the Host Transcriptome following Infection with Entamoeba histolytica
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60. Sirtuin 3 Deficiency Aggravates Kidney Disease in Response to High-Fat Diet through Lipotoxicity-Induced Mitochondrial Damage
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61. AGEs Decreased SIRT3 Expression and SIRT3 Activation Protected AGEs-Induced EPCs’ Dysfunction and Strengthened Anti-oxidant Capacity
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63. Neuroprotective role of retinal SIRT3 against acute photo-stress
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64. Sirt3 is dispensable for oocyte quality and female fertility in lean and obese mice
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65. SIRT3-mediated cardiac remodeling/repair following myocardial infarction
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66. Overexpression of NMNAT3 improves mitochondrial function and enhances antioxidative stress capacity of bone marrow mesenchymal stem cells via the NAD+-Sirt3 pathway
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67. Chemical Acetylation and Deacetylation
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68. Dihydromyricetin attenuates palmitic acid-induced oxidative stress by promoting autophagy via SIRT3-ATG4B signaling in hepatocytes
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69. The plasticizer BBP selectively inhibits epigenetic regulator sirtuins
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70. Regulation of Chondrocyte Metabolism and Osteoarthritis Development by Sirt5 Through Protein Lysine Malonylation
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71. Induction of Posttranslational Modifications of Mitochondrial Proteins by ATP Contributes to Negative Regulation of Mitochondrial Function
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73. Ellagic acid induces beige remodeling of white adipose tissue by controlling mitochondrial dynamics and SIRT3
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74. A review on SIRT3 and its natural small molecule activators as a potential Preventive and therapeutic target
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75. Intestinal SIRT3 overexpression in mice improves whole body glucose homeostasis independent of body weight
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76. SIRT3 as a regulator of hepatic autophagy
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77. SIRT3 affects mitochondrial metabolic reprogramming via the AMPK–PGC‐1α axis in the development of benign prostatic hyperplasia
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79. Longevity and healthy ageing genes FOXO3A and SIRT3: Serum protein marker and new road map to burst oxidative stress by Withania somnifera
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80. Depletion of Sirt3 leads to the impairment of adipogenic differentiation and insulin resistance via interfering mitochondrial function of adipose-derived human mesenchymal stem cells
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82. Autophagy in Ischemic Livers: A Critical Role of Sirtuin 1/Mitofusin 2 Axis in Autophagy Induction
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