SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome

Hirschey, Matthew D., Shimazu, Tadahiro, Jing, Enxuan, Grueter, Carrie A., Collins, Amy M., Aouizerat, Bradley, Stančáková, Alena, Goetzman, Eric +13 more·2011·Molecular Cell

Cited by (787)

Items 501–600 of 787

  1. Epigenetic Manifestation of Metabolic Syndrome and Dietary Management
    Nidhi Chaudhary, Kiran Kumar Nakka, Nilanjana Maulik, Samit Chattopadhyay · 2012 · Antioxidants and Redox Signaling
  2. CELL BIOLOGY SYMPOSIUM: METABOLIC RESPONSES TO STRESS: FROM ANIMAL TO CELL: Poor maternal nutrition during gestation: effects on offspring whole-body and tissue-specific metabolism in livestock species1,2
    Kristen E Govoni, Sarah A Reed, Steven A Zinn · 2019 · Journal of Animal Science
  3. Unlocking the Nexus of Sirtuins: A Comprehensive Review of Their Role in Skeletal Muscle Metabolism, Development, and Disorders
    Bahareldin Ali Abdalla, Xinwei Xiong, Xuewen Chai, Qiao Xu, Jishang Gong, Jiguo Xu · 2024 · International Journal of Biological Sciences
  4. Metabolism and chromatin dynamics in health and disease
    Hanah Rodriguez, Haloom Rafehi, Mrinal R. Bhave, Assam El‐Osta · 2016 · Molecular Aspects of Medicine
  5. SIRT2 Deficiency Exacerbates Hepatic Steatosis via a Putative Role of the ER Stress Pathway
    Helena Leal, João Almeida Cardoso, Patrícia Valério, Marta Quatorze, Vítor Carmona, Janete Cunha‐Santos, Luís Pereira de Almeida, Cláudia MF Pereira, Cláudia Cavadas, Pedro Gomes · 2022 · International Journal of Molecular Sciences
  6. Biochemical Mechanisms of Sirtuin-Directed Protein Acylation in Hepatic Pathologies of Mitochondrial Dysfunction
    Courtney D. McGinnis, Erin Q. Jennings, Peter S. Harris, James J. Galligan, Kristofer S. Fritz · 2022 · Cells
  7. Both prolonged high-fat diet consumption and calorie restriction boost hepatic NAD+ metabolism in mice
    Xiaojing Wei, Chuanfei Wei, Yutian Tan, Ximing Dong, Zhao Yang, Jianqun Yan, Xiao Min Luo · 2023 · The Journal of Nutritional Biochemistry
  8. The central role of mitochondrial metabolism in hepatic steatosis
    Sanda Win, Tin Aung Than, Neil Kaplowitz, Nicole Wong, Aliza Arya, Zin Thandar Win, Shwe Hlaing Win, Ei Phyu, Christina Kuemerle, Jake Suh et al. · 2024 · Exploration of Digestive Diseases
  9. With mouse age comes wisdom: A review and suggestions of relevant mouse models for age-related conditions
    Susanne Drechsler, Marina A. Lynch, Susana Novella, Herminia González Navarro, Silva Katusic Hecimovic, Erica Barini, Valter Tucci, Rui Eduardo Castro, Roosmarijn E. Vandenbroucke, Marcin Filip Osuchowski et al. · 2016 · Mechanisms of Ageing and Development
  10. Sirtuiny i ich rola w regulacji metabolizmu
    Zuzanna Frydzińska, Aleksandra Owczarek, Katarzyna Winiarska · 2019 · Postępy Biochemii
  11. Molecular link between circadian clocks and cardiac function: a network of core clock, slave clock, and effectors
    Weiyi Xu, Mukesh K. Jain, Lilei Zhang · 2020 · Current Opinion in Pharmacology
  12. Sirt3 in POMC neurons controls energy balance in a sex- and diet-dependent manner
    Mar Quiñones, René Hernández-Bautista, Daniel Beiroa, Violeta Heras, Francisco Leonardo Torres‐Leal, Brian Lam, Ana Senra, Johan Fernø, Alícia G. Gómez-Valadés, Markus Schwaninger et al. · 2021 · Redox Biology
  13. Sirtuin 3: a major control point for obesity-related metabolic diseases?
    Sean Alec Newsom, Kristen E. Boyle, Jacob E. Friedman · 2013 · Drug Discovery Today Disease Mechanisms
  14. Human umbilical cord-derived mesenchymal stem cells ameliorate liver fibrosis by improving mitochondrial function via Slc25a47-Sirt3 signaling pathway
    Chen, Ping, Yuan, Mengqin, Yao, Lichao, Xiong, Zhiyu, Liu, Pingji, Wang, Zheng, Jiang, Yingan, Li, Lanjuan · 2024 · Biomedicine & Pharmacotherapy
  15. SIRT3-Mediated Mitochondrial Regulation and Driver Tissues in Systemic Aging
    Kate Šešelja, Ena Šimunić, Sandra Sobočanec, Iva I. Podgorski, Marija Pinterić, Marijana Popović Hadžija, Tihomir Balog, Robert Belužić · 2025 · Genes
  16. Salvaging hope: Is increasing NAD+ a key to treating mitochondrial myopathy?
    Robert Neil Lightowlers, Zofia M. Chrzanowska‐Lightowlers · 2014 · EMBO Molecular Medicine
  17. Sirtuin deficiency and the adverse effects of fructose and uric acid synthesis
    Bernardo Rodríguez‐Iturbe, Richard J. Johnson, Miguel Angel Lanaspa, Takahiko Nakagawa, Fernando E. García‐Arroyo, Laura Gabriela Sánchez‐Lozada · 2022 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  18. Exercise performed during pregnancy positively modulates liver metabolism and promotes mitochondrial biogenesis of female offspring in a rat model of diet-induced gestational diabetes
    Jelena Stevanović, Jorge Beleza, Pedro M. Coxito, Hugo Rocha, Tiago Bordeira Gaspar, Fátima Gärtner, Rossana Correia, Rui Fernandes, Paulo Jorge Oliveira, António A.M.R. Ascensão et al. · 2022 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  19. Sirt3 deficiency induced down regulation of insulin degrading enzyme in comorbid Alzheimer’s disease with metabolic syndrome
    Alpna Tyagi, Musa Musa, Wladimir Labeikovsky, Subbiah Pugazhenthi · 2022 · Scientific Reports
  20. An integrated perspective and functional impact of the mitochondrial acetylome
    Francisco Manuel Lemos Amado, António Sousa Barros, Ana Lúcia Azevedo, Rui Miguel Pinheiro Vitorino, Rita M. Ferreira · 2014 · Expert Review of Proteomics
  21. The Protective Effect of 1,25(OH)2D3 on Myocardial Function is Mediated via Sirtuin 3-Regulated Fatty Acid Metabolism
    Jingxin Yang, Yalin Zhang, Yiming Pan, Can Sun, Zuwang Liu, Ning Liu, Yu Fu, Xiaofeng Li, Ye Li, Juan Kong · 2021 · Frontiers in Cell and Developmental Biology
  22. Nicotinamide riboside supplementation confers marginal metabolic benefits in obese mice without remodeling the muscle acetyl-proteome
    Ashley S. Williams, Timothy R. Koves, Yasminye D. Pettway, James A. Draper, Dorothy H. Slentz, Paul A. Grimsrud, Olga Ilkayeva, Deborah M. Muoio · 2021 · iScience
  23. Exercise Training Prevents Doxorubicin-induced Mitochondrial Dysfunction of the Liver
    J. Matthew Hinkley, Aaron B. Morton, Noriko Ichinoseki‐Sekine, Andres Mor Huertas, Ashley J. Smuder · 2019 · Medicine & Science in Sports & Exercise
  24. Hyperinsulinemia contributes to impaired-glucose-tolerance-induced renal injury via mir-7977/SIRT3 signaling
    Zhongai Gao, Ziyan Wang, Hong Zhu, Xinxin Yuan, Mengdi Sun, Jingyu Wang, Minxia Zuo, Xiao Cui, Ying Han, Yi Zhang et al. · 2020 · Therapeutic Advances in Chronic Disease
  25. A Synthetic Epoxydocosapentaenoic Acid Analogue Ameliorates Cardiac Ischemia/Reperfusion Injury: The Involvement of the Sirtuin 3–NLRP3 Pathway
    Ahmed M. Darwesh, Wesam Bassiouni, Adeniyi Michael Adebesin, Abdul Sattar Mohammad, John Russell Falck, John M. Seubert · 2020 · International Journal of Molecular Sciences
  26. Histone acylation at a glance
    Saikat Bhattacharya, Benjamin P. Tu · 2024 · Journal of Cell Science
  27. Interplay Between SIRT-3, Metabolism and Its Tumor Suppressor Role in Hepatocellular Carcinoma
    Serena De Matteis, Anna Maria Granato, Roberta Napolitano, Chiara Molinari, Martina Valgiusti, Daniele Santini, Francesco Giuseppe Foschi, Giorgio Ercolani, Umberto Vespasiani Gentilucci, Luca Faloppi et al. · 2017 · Digestive Diseases and Sciences
  28. Elevated Nicotinamide Phosphoribosyl Transferase in Skeletal Muscle Augments Exercise Performance and Mitochondrial Respiratory Capacity Following Exercise Training
    Bram Brouwers, Natalie A. Stephens, Sheila R. Costford, Meghan E. Hopf, Julio E. Ayala, Fanchao Yi, Hui Xie, Jian‐Liang Li, Stephen J. Gardell, Lauren Marie Sparks et al. · 2018 · Frontiers in Physiology
  29. Dysregulated Epigenetic Modifications in the Pathogenesis of NAFLD-HCC
    Fung Zhao · 2018 · Advances in experimental medicine and biology
  30. ‘There and Back Again’—Forward Genetics and Reverse Phenotyping in Pulmonary Arterial Hypertension
    Emilia M. Swietlik, Matina Prapa, Jennifer M. Martin, Divya Pandya, Kathryn Auckland, Nicholas W. Morrell, Stefan Gräf · 2020 · Genes
  31. SNPs for Genes Encoding the Mitochondrial Proteins Sirtuin3 and Uncoupling Protein 2 Are Associated With Disease Severity, Type 2 Diabetes, and Outcomes in Patients With Pulmonary Arterial Hypertension and This Is Recapitulated in a New Mouse Model Lacking Both Genes
    Yongneng Zhang, Sotirios D. Zervopoulos, Aristeidis E. Boukouris, Maria Areli Lorenzana Carrillo, Bruno Saleme, Linda Webster, Yongsheng Liu, Alois Haromy, Seyed Amirhossein Tabatabaei Dakhili, John R. Ussher et al. · 2021 · Journal of the American Heart Association
  32. Nicotinamide reprograms adipose cellular metabolism and increases mitochondrial biogenesis to ameliorate obesity
    Chengting Luo, Changmei Yang, Xueying Wang, Yuling Chen, Xiaohui Liu, Haiteng Deng · 2022 · The Journal of Nutritional Biochemistry
  33. Dihydromyricetin Improves High‐Fat Diet‐Induced Hyperglycemia through ILC3 Activation via a SIRT3‐Dependent Mechanism
    Jie Zhou, Pengfei Hou, Yu Yao, Jing Yue, Qianyong Zhang, Long Yi, Mantian Mi · 2022 · Molecular Nutrition & Food Research
  34. Molecular classification of fatty liver by high‐throughput profiling of protein post‐translational modifications
    Yasuyo Urasaki, Ronald R. Fiscus, Thuc T. Le · 2016 · The Journal of Pathology
  35. SIRT3 and GCN5L regulation of NADP+- and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2
    Katarína Smolková, Jitka Špačková, Klára Gotvaldová, Aleš Dvořák, Alena Křenková, Martin Hubálek, Blanka Holendová, Libor Vı́tek, Petr Ježek · 2020 · Scientific Reports
  36. Profilin 1 and Mitochondria—Partners in the Pathogenesis of Coronary Artery Disease?
    Elżbieta Paszek, Wojciech Zajdel, Tomasz Rajs, Krzysztof F. Zmudka, Jacek Legutko, Paweł Kleczyński · 2021 · International Journal of Molecular Sciences
  37. Characteristics of expression and regulation of sirtuins in chicken (Gallus gallus)
    Junxiao Ren, Naiyi Xu, Zheng Ma, Yanmin Li, Cuicui Li, Yanbin Wang, Yadong Tian, Xiaojun Liu, Xiangtao Kang · 2016 · Genome
  38. Understanding mitochondrial biogenesis through energy sensing pathways and its translation in cardio-metabolic health
    Abhijit M. Nirwane, Anuradha Sandeep Majumdar · 2017 · Archives of Physiology and Biochemistry
  39. The Lifespan Extension Ability of Nicotinic Acid Depends on Whether the Intracellular NAD+ Level Is Lower than the Sirtuin-Saturating Concentrations
    Nae-Cherng Yang, Yu-Hung Cho, Inn Lee · 2019 · International Journal of Molecular Sciences
  40. Mitochondria in the Pulmonary Vasculature in Health and Disease: Oxygen‐Sensing, Metabolism, and Dynamics
    Asish Dasgupta, Danchen Wu, Lian Tian, Ping Yu Xiong, Kimberly J. Dunham‐Snary, Kuang‐Hueih Chen, Elahe Alizadeh, Mehras Motamed, François Potus, Charles C.T. Hindmarch et al. · 2020 · Comprehensive physiology
  41. Application of a real-ambient fine particulate matter exposure system on different animal models
    Yuanyuan Song, Lifang Zhao, Zenghua Qi, Yanhao Zhang, Guodong Cao, Ruijin Li, Lin Zhu, Zhu Yang, Chuan Dong, Zongwei Cai · 2021 · Journal of Environmental Sciences
  42. Cellular carbon stress is a mediator of obesity-associated osteoarthritis development
    Huan Liu, Thomas J. Rosol, Roshini Sathiaseelan, Shivani N. Mann, Michael B. Stout, Shouan Zhu · 2021 · Osteoarthritis and Cartilage
  43. Liver-specific overexpression of SIRT3 enhances oxidative metabolism, but does not impact metabolic defects induced by high fat feeding in mice
    Brenna Osborne, Jane Reznick, Lauren E. Wright, David A. Sinclair, Gregory James Cooney, Nigel A. Turner · 2022 · Biochemical and Biophysical Research Communications
  44. The Role of Mitochondria in Metabolic Syndrome–Associated Cardiomyopathy
    Jiayu Li, Jingye Li, Yijun Chen, Wenyu Hu, Xuhe Gong, Hui Qiu, Hui Chen, Yanguo Xin, Hongwei Li · 2022 · Oxidative Medicine and Cellular Longevity
  45. A novel epigenetic mechanism of FXR inhibiting GLP-1 secretion via miR-33 and its downstream targets
    Pengzhou Li, Xiang Gao, Xulong Sun, Weizheng Li, Bo Yi, Liyong Zhu · 2019 · Biochemical and Biophysical Research Communications
  46. Role of Sirt3 in Differential Sex-Related Responses to a High-Fat Diet in Mice
    Marija Pinterić, Iva I. Podgorski, Marijana Popović Hadžija, Ivana Tartaro Bujak, Ana Dekanić, Robert Bagarić, Vladimir Farkaš, Sandra Sobočanec, Tihomir Balog · 2020 · Antioxidants
  47. Major royal jelly proteins prevents NAFLD by improving mitochondrial function and lipid accumulation through activating the AMPK / SIRT3 pathway in vitro
    Xiaochen Zhang, Xinyang Lu, Yingjun Zhou, Xinyu Guo, Yaning Chang · 2021 · Journal of Food Science
  48. HDAC in obesity: A critical insight
    Nijhawan, Priya, Behl, Tapan, Khullar, Gaurav, Pal, Giridhari, Kandhwal, Mimansa, Goyal, Amit · 2020 · Obesity Medicine
  49. Role of SIRT3 in bone homeostasis and its application in preventing and treating bone diseases
    Ke Xu, Jing Li, Ruiming Wen, Bo Chang, Yang Cheng, Xuejie Yi · 2023 · Frontiers in Pharmacology
  50. Impact of Obesity on Pubertal Timing and Male Fertility
    Valeria Calcaterra, Lara Tiranini, Vittoria Carlotta Magenes, Virginia Rossi, Laura Cucinella, Rossella Elena Nappi, Gianvincenzo Zuccotti · 2025 · Journal of Clinical Medicine
  51. Fasting increases susceptibility to acute myocardial ischaemia/reperfusion injury through a sirtuin-3 mediated increase in fatty acid oxidation
    Andrew R. Hall, Qutuba G. Karwi, Sanjeev Kumar, Rachel K Dongworth, Dunja Aksentijević, Tariq Altamimi, Kevin Timothy Fridianto, Kroekkiat Chinda, Sauri Hernández‐Reséndiz, Mohammad U. Mahmood et al. · 2022 · Scientific Reports
  52. α-Lipoic acid promotes α-tubulin hyperacetylation and blocks the turnover of mitochondria through mitophagy
    Michael Wayne Stoner, Dharendra Thapa, Manling Zhang, Gregory A. Gibson, Michael Joseph Calderon, Claudette M. St. Croix, Iain Scott · 2016 · Biochemical Journal
  53. Role of Sirtuins in Retinal Function Under Basal Conditions
    Jonathan B. Lin, Shunsuke Kubota, Raúl Mostoslavsky, Rajendra S. Apte · 2018 · Advances in experimental medicine and biology
  54. Metabolic pathways at the crossroads of diabetes and inborn errors
    Eric S. Goetzman, Zhenwei Gong, Manuel Schiff, Yan Wang, Radhika H. Muzumdar · 2017 · Journal of Inherited Metabolic Disease
  55. Mitochondrial unfolded protein response in regulatory T cell function: a protective mechanism in immune aging
    Lillie Lewis, Deepa Valvi, Roberto Gedaly, Francesc Martí · 2025 · Frontiers in Immunology
  56. Celastrus orbiculatus Thunb. extracts and celastrol alleviate NAFLD by preserving mitochondrial function through activating the FGF21/AMPK/PGC-1α pathway
    Junli Xue, Yunchao Liu, Boyan Liu, Xiubin Jia, Xinsheng Fang, Shucun Qin, Ying Zhang · 2024 · Frontiers in Pharmacology
  57. Synergistic Beneficial Effects of Resveratrol and Diet on High-Fat Diet-Induced Obesity
    Osama Abo Alrob, Ramzi Al-Horani, Zaid Altaany, Mohammad B. Nusair · 2022 · Medicina
  58. Chronic exercise remodels the lysine acetylome in the mouse hippocampus
    Ping Qian, Feifei Ma, Wanyu Zhang, Dingding Cao, Luya Li, Zhuo Liu, Pei Pei, Ting Zhang, Shan Wang, Jianxin Wu · 2022 · Frontiers in Molecular Neuroscience
  59. Assessment of global histone acetylation in pediatric and adolescent obesity: Correlations with SIRT1 expression and metabolic-inflammatory profiles
    Nima Taghizadeh, Soha Mohammadi, Zeynab Yousefi, Pegah Golpour, Alemeh Taheri, Mohammad Hasan Maleki, Mitra Nourbakhsh, Mona Nourbakhsh, Maryam Razzaghy Azar · 2023 · PLoS ONE
  60. Protein acetylation links the circadian clock to mitochondrial function
    Guillaume Rey, Akhilesh B. Reddy · 2013 · Proceedings of the National Academy of Sciences
  61. The postpartum effect of maternal diabetes on the circulating levels of sirtuins and superoxide dismutase
    Samar Sultan, Nada Alzahrani, Kalthoom Al‐Sakkaf · 2017 · FEBS Open Bio
  62. Chronic High Fat Diet Intake Impairs Hepatic Metabolic Parameters in Ovariectomized Sirt3 KO Mice
    Marija Pinterić, Iva I. Podgorski, Marijana Popović Hadžija, Ivana Tartaro Bujak, Ana Tadijan, Tihomir Balog, Sandra Sobočanec · 2021 · International Journal of Molecular Sciences
  63. Sirtuins, Healthspan, and Longevity in Mammals
    William Giblin, David B. Lombard · 2015 · Elsevier eBooks
  64. Sirtuin activation as a therapeutic approach against inborn errors of metabolism
    Bleeker, Jeannette C., Houtkooper, Riekelt H. · 2016 · Journal of Inherited Metabolic Disease
  65. Sirtuins as Therapeutic Targets for Treating Cancer, Metabolic Diseases, and Neurodegenerative Diseases
    Maxwell Akantibila, Valerie J. Carabetta · 2025 · Pharmaceuticals
  66. Multiple Roles of Sirtuin 6 in Adipose Tissue Inflammation
    Eun Ju Bae, Byung‐Hyun Park · 2023 · Diabetes & Metabolism Journal
  67. A high-fat diet increases hepatic mitochondrial turnover through restricted acetylation in a NAFLD mouse model
    Mirjavid Aghayev, Andrea Arias-Alvarado, Sergei Ilchenko, Josephine Lepp, Iain Scott, Yeong‐Renn Chen, Guofang Zhang, Tsung‐Heng Tsai, Takhar Kasumov · 2023 · American Journal of Physiology-Endocrinology and Metabolism
  68. SIRT3 deficiency reduces PFKFB3-driven T-cell glycolysis and promotes arthritic inflammation
    Tingting Wang, Taotao Han, Xinyue Xiao, Dan Guo, Xin Sun, Yudong Liu, Lidan Zhao, Haojie Xu, Rong Li, Lingjuan Jiang et al. · 2025 · Science China Life Sciences
  69. Quantitative Acetylomics Reveals Dynamics of Protein Lysine Acetylation in Mouse Livers During Aging and Upon the Treatment of Nicotinamide Mononucleotide
    Jingshu Li, Ye Cao, Kongyan Niu, Jiaqian Qiu, Han Wang, Yingnan You, Dean Li, Yu Luo, Zheng‐Jiang Zhu, Yaoyang Zhang et al. · 2022 · Molecular & Cellular Proteomics
  70. Short- and long-term effects of high-fat diet feeding and voluntary exercise on hepatic lipid metabolism in mice
    Saki Yoshimura, Shihoko Nakashima, Yuki Tomiga, Shotaro Kawakami, Yoshinari Uehara, Yasuki Higaki · 2018 · Biochemical and Biophysical Research Communications
  71. Dietary fatty acids as nutritional modulators of sirtuins: a systematic review
    Ana Paula Silva Caldas, Daniela Mayumi Usuda Prado Rocha, Josefina Bressan, Helen Hermana Miranda Hermsdorff · 2020 · Nutrition Reviews
  72. Neuronal SIRT3 Deletion Predisposes to Female-Specific Alterations in Cellular Metabolism, Memory, and Network Excitability
    Jennifer N. Pearson-Smith, Ruth E. Fulton, Christopher Quoc Huynh, Anna G. Figueroa, Gia B. Huynh, Liping Liang, Lindsey B. Gano, Cole R. Michel, Nichole A. Reisdorph, Richard M. Reisdorph et al. · 2023 · Journal of Neuroscience
  73. Biological Functions and Potential Therapeutic Significance of O-GlcNAcylation in Hepatic Cellular Stress and Liver Diseases
    Zun Mao, Junpeng Mu, Zhixiang Gao, Shile Huang, Long Chen · 2024 · Cells
  74. Role of sirtuins in obesity and osteoporosis: molecular mechanisms and therapeutic targets
    Yi Du, Yuying Huo, Yujia Yang, Peiqi Lin, Wuzheng Liu, Ziqin Wang, Wenqi Zeng, Jiahui Li, Zhonghan Liang, Chenyue Yuan et al. · 2025 · Cell Communication and Signaling
  75. Mitochondrial KMT9 methylates DLAT to control pyruvate dehydrogenase activity and prostate cancer growth
    Yanhan Jia, Sheng Wang, Sylvia Urban, Judith M. Müller, Manuela Sum, Qing Wang, Helena Bauer, Uwe Schulte, Heike Rampelt, Nikolaus Pfanner et al. · 2025 · Nature Communications
  76. Adipocyte-expressed SIRT3 manipulates carnitine pool to orchestrate metabolic reprogramming and polarization of macrophages
    Jiali Chen, Fei Zhou, Lei Zhang, Ruohan Lou, Cangman Zhang, Jian‐Bo Wan, Xiaojun Ma, Ligen Lin · 2025 · Cell Death and Disease
  77. Dietary Sodium and Nonalcoholic Fatty Liver Disease: A Systematic Review
    Guilherme da Silva Ferreira, Sérgio Catanozi, Marisa Passarelli · 2023 · Antioxidants
  78. Integrative Therapies in Cancer
    Keith I. Block, Penny B. Block, Charlotte Gyllenhaal · 2015 · Integrative Cancer Therapies
  79. Nutritional stress exacerbates hepatic steatosis induced by deletion of the histidine nucleotide-binding (Hint2) mitochondrial protein
    Juliette Martin, Maria Luisa Balmer, Saranya Rajendran, Olivier Maurhofer, Jean‐François Dufour, Marie V. St–Pierre · 2016 · American Journal of Physiology-Gastrointestinal and Liver Physiology
  80. Fatty acid type–specific regulation of SIRT1 does not affect insulin sensitivity in human skeletal muscle
    Andreas Mæchel Fritzen, Anne‐Marie Lundsgaard, Jacob Fuglsbjerg Jeppesen, Kim Anker Sjøberg, Louise D. Høeg, Henrik Hall Deleuran, Jørgen F. P. Wojtaszewski, Erik Arne Richter, Bente Kiens · 2019 · The FASEB Journal
  81. Perturbed Brain Glucose Metabolism Caused by Absent SIRT3 Activity
    Tibor Kristián, Arman J. Karimi, Adam D. Fearnow, Jaylyn Waddell, Mary C. McKenna · 2021 · Cells
  82. Mitochondrial sirtuins genetic variations and gastric cancer risk: Evidence from retrospective observational study
    Ishrat Mahjabeen, Muhammad Rizwan, Gul Fareen, Malik Waqar Ahmed, Amir Farooq Khan, Mahmood Akhtar Kayani · 2021 · Gene
  83. SIRT3 Directs Carbon Traffic in Muscle to Promote Glucose Control
    Frank K. Huynh, Deborah M. Muoio, Matthew D. Hirschey · 2015 · Diabetes
  84. Early postnatal feed restriction reduces liver connective tissue levels and affects H3K9 acetylation state of regulated genes associated with protein metabolism in low birth weight pigs
    Constance Nebendahl, Solvig Görs, Elke Albrecht, Ricarda Krüger, Karen Martens, Katrin Giller, Harald Michael Hammon, Gerald H Rimbach, Cornelia C. Metges · 2015 · The Journal of Nutritional Biochemistry
  85. Redox regulation of epigenetic and epitranscriptomic gene regulatory pathways in plants
    Juline Auverlot, Avilien Dard, Julio Sáez‐Vasquez, Jean‐Philippe Reichheld · 2024 · Journal of Experimental Botany
  86. The dual nature of DNA damage response in obesity and bariatric surgery-induced weight loss
    David Israel Escobar Marcillo, Valeria Guglielmi, Grete Francesca Privitera, Michele Signore, Valeria Simonelli, Federico Manganello, Ambra Dell'Orso, Serena Laterza, Eleonora Parlanti, Alfredo Pulvirenti et al. · 2024 · Cell Death and Disease
  87. SIRT7 Is a Lysine Deacylase with a Preference for Depropionylation and Demyristoylation
    Mohammad Golam Kibria, Tatsuya Yoshizawa, Tianli Zhang, Katsuhiko Ono, Tomoya Mizumoto, Yoshifumi Sato, Tomohiro Sawa, Kazuya Yamagata · 2025 · International Journal of Molecular Sciences
  88. Acetylation of the Mitochondrial Chaperone GRP75 Governs ER‐Mitochondrial Calcium Homeostasis and Hepatocyte Insulin Resistance
    Danni Wang, Jiaqi Zhang, Xinyu Yang, Qiqi Zhang, Xiuya Hu, Xin Lu, Hao Li, Xue Li Bai, Kai Zhang, Michael N. Sack et al. · 2025 · Advanced Science
  89. Therapeutic opportunities to modulate immune tolerance through the metabolism-chromatin axis
    Anne Lise Ferrara, Antonietta Liotti, Antonio Pezone, Veronica De Rosa · 2022 · Trends in Endocrinology and Metabolism
  90. An Update on the Role of the Microbiome in Non-alcoholic Fatty Liver Disease Pathogenesis, Diagnosis, and Treatment
    Marialena Mouzaki, Rohit Seth Loomba · 2020 · Current Treatment Options in Gastroenterology
  91. Sirt3 regulates adipogenesis and adipokine secretion via its enzymatic activity
    Oanh Ma, Truc Le, George C. Talbott, Tram HoangThao Nguyen, Dorothy Ha, Linh Ho · 2020 · Pharmacology Research & Perspectives
  92. Muscle‐specific sirtuin 3 overexpression does not attenuate the pathological effects of high‐fat/high‐sucrose feeding but does enhance cardiac SERCA2a activity
    Christopher J. Oldfield, Teri L. Moffatt, Kimberley A. O’Hara, Bo Xiang, Vernon Wayne Dolinsky, Todd Ashley Duhamel · 2021 · Physiological Reports
  93. LncRNA DLEU2 regulates sirtuins and mitochondrial respiratory chain complex IV: a novel pathway in obesity and offspring’s health
    Jian Zhang, Matthew Kay, Min Hi Park, Sunitha Meruvu, Catherine A. Powell, Mahua Choudhury · 2022 · International Journal of Obesity
  94. Hepatic proteomic analysis revealed altered metabolic pathways in insulin resistant Akt1+/−/Akt2−/− mice
    Brian Pedersen, Weiwen Wang, Jared F. Taylor, Omar Salem Khattab, Yuhan Chen, Robert A. Edwards, Puya G. Yazdi, Ping H. Wang · 2015 · Metabolism
  95. Plasma Proteomics Identifies B2M as a Regulator of Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction
    Jia-Rong Jheng, Jacqueline T. DesJardin, Yi-Yun Chen, Joshua R. Huot, Yang Bai, Todd G. Cook, Lainey M. Hibbard, Jennifer M. Rupp, Amanda Jo Fisher, Yingze Zhang et al. · 2024 · Arteriosclerosis Thrombosis and Vascular Biology
  96. The role of protein acetylation in regulating mitochondrial fusion and fission
    Golam M. Uddin, Rafa Abbas, Timothy E. Shutt · 2021 · Biochemical Society Transactions
  97. Establishment of reference values for the lysine acetylation marker Nɛ-acetyllysine in small volume human plasma samples by a multi-target LC–MS/MS method
    Arne Gessner, Maren Mieth, Daniel Auge, Anja Chafai, Fabian Müller, Martin F. Fromm, Renke Maas · 2019 · Amino Acids
  98. Mitochondria Lysine Acetylation and Phenotypic Control
    Federica Ciregia · 2019 · Advances in experimental medicine and biology
  99. Increased fatty acid oxidation enzyme activity in the hearts of mice fed a high fat diet does not correlate with improved cardiac contractile function
    Dharendra Thapa, Janet R. Manning, Bellina A.S. Mushala, Michael Wayne Stoner, Manling Zhang, Iain Scott · 2020 · Current Research in Physiology
  100. The Effect of Six-Week HIIT Swimming Exercise and Resveratrol Supplementation on the Level of SIRT3 in Frontal Lobe of Aged Rats
    Amin Mehrabi, Abbas Ali Gaeini, Reza Nouri, Farhad Daryanoosh · 2021 · The Neuroscience Journal of Shefaye Khatam