CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons

Billon, Pierre, Bryant, Eric E., Joseph, Sarah A., Nambiar, Tarun S., Hayward, Samuel B., Rothstein, Rodney, Ciccia, Alberto·2017·Molecular Cell

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Items 101–200 of 365

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  3. Yeast genetic interaction screens in the age of CRISPR/Cas
    Neil R. Adames, Jenna E. Gallegos, Jean Peccoud · 2018 · Current Genetics
  4. Marker-free co-selection for successive rounds of prime editing in human cells
    Sébastien Levesque, Diana Mayorga, Jean-Philippe Fiset, Claudia Goupil, Alexis Duringer, A Loiselle, Eva Bouchard, Daniel Agudelo, Yannick Doyon · 2022 · Nature Communications
  5. CRISPR-Combo–mediated orthogonal genome editing and transcriptional activation for plant breeding
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  6. Base editor screens for in situ mutational scanning at scale
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  8. Intrinsic Nucleotide Preference of Diversifying Base Editors Guides Antibody Ex Vivo Affinity Maturation
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  9. Applications and Prospects of CRISPR/Cas9-Mediated Base Editing in Plant Breeding
    Yizhen Li, Jing Yi Liang, Bufang Deng, Yingli Jiang, Jingyan Zhu, Like Chen, Min Li, Juan Li · 2023 · Current Issues in Molecular Biology
  10. Unlocking the potential of cultivated meat through cell line engineering
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  11. Synergizing CRISPR/Cas9 off-target predictions for ensemble insights and practical applications
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  12. A multiplexed gRNA piggyBac transposon system facilitates efficient induction of CRISPRi and CRISPRa in human pluripotent stem cells
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  13. Unlocking nature’s biosynthetic potential by directed genome evolution
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  14. Development of an Efficient C-to-T Base-Editing System and Its Application to Cellulase Transcription Factor Precise Engineering in Thermophilic Fungus Myceliophthora thermophila
    Chenyang Zhang, Nan Li, Lang Rao, Jingen Li, Qian Liu, Chaoguang Tian · 2022 · Microbiology Spectrum
  15. Programmable adenine deamination in bacteria using a Cas9–adenine-deaminase fusion
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  16. Genome Editing for CNS Disorders
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  17. Mosaic CRISPR-stop enables rapid phenotyping of nonsense mutations in essential genes
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  18. A Tale of Ice and Fire: The Dual Role for 17β-Estradiol in Balancing DNA Damage and Genome Integrity
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  19. Strategies for precise gene edits in mammalian cells
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  20. Stress tolerance enhancement via SPT15 base editing in Saccharomyces cerevisiae
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  21. CRISPR-Cas Genome Editing Technique for Fish Disease Management: Current Study and Future Perspective
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  22. Base editors: development and applications in biomedicine
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  23. Disruptive Technology: CRISPR/Cas-Based Tools and Approaches
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  24. Harnessing the evolving CRISPR/Cas9 for precision oncology
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  25. Precise genome editing of the Kozak sequence enables bidirectional and quantitative modulation of protein translation to anticipated levels without affecting transcription
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  26. Efficient and precise base editing in rabbits using human APOBEC3A-nCas9 fusions
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  27. Biosystems design by directed evolution
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  28. Programmable Single and Multiplex Base-Editing in Bombyx mori Using RNA-Guided Cytidine Deaminases
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  29. BE4max and AncBE4max Are Efficient in Germline Conversion of C:G to T:A Base Pairs in Zebrafish
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  30. Cytosine Base Editor (hA3A-BE3-NG)-Mediated Multiple Gene Editing for Pyramid Breeding in Pigs
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  31. Next-Generation Sequencing and the CRISPR-Cas Nexus: A Molecular Plant Virology Perspective
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  32. Neuro-Immuno-Gene- and Genome-Editing-Therapy for Alzheimer’s Disease: Are We There Yet?
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  34. Approaches to Enhance Precise CRISPR/Cas9-Mediated Genome Editing
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  35. Efficient silencing of hepatitis B virus S gene through CRISPR‐mediated base editing
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  36. Critical contribution of mitochondria in the development of cardiomyopathy linked to desmin mutation
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  37. Phenotypic novelty by CRISPR in plants
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  38. Innovations in CRISPR technology
    Alexandra K. Brooks, Thomas Gaj · 2018 · Current Opinion in Biotechnology
  39. CRISPR Start-Loss: A Novel and Practical Alternative for Gene Silencing through Base-Editing-Induced Start Codon Mutations
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  40. CRISPR-Mediated Base Conversion Allows Discriminatory Depletion of Endogenous T Cell Receptors for Enhanced Synthetic Immunity
    Roland Preece, Andrea Pavesi, Soragia Athina Gkazi, Kerstin A. Stegmann, Christos Georgiadis, Zhi Ming Tan, Jia Ying Joey Aw, Mala K. Maini, Antonio Bertoletti, Waseem Qasim · 2020 · Molecular Therapy — Methods & Clinical Development
  41. Nitroreductase Increases Menadione-Mediated Oxidative Stress inAspergillus nidulans
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  42. Development and Application of CRISPR-Cas Based Tools
    Yanping Hu, Wei Li · 2022 · Frontiers in Cell and Developmental Biology
  43. Unclasping potentials of genomics and gene editing in chickpea to fight climate change and global hunger threat
    Charul Singh, Ramesh Kumar, Hansa Sehgal, Sharmista Bhati, Tripti Singhal, Gayacharan, Manduparambil Subramanian Nimmy, Renu Yadav, Santosh Kumar Gupta, Naglaa Abdelmoneim Abdallah et al. · 2023 · Frontiers in Genetics
  44. Base editors: modular tools for the introduction of point mutations in living cells
    Mallory Evanoff, Alexis C. Komor · 2019 · Emerging Topics in Life Sciences
  45. Precision engineering of the probiotic Escherichia coli Nissle 1917 with prime editing
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  46. Applications of CRISPR Genome Editing to Advance the Next Generation of Adoptive Cell Therapies for Cancer
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  47. Increasing the Targeting Scope of CRISPR Base Editing System Beyond NGG
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  48. Genome Editing in Engineered T Cells for Cancer Immunotherapy
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  49. Acceleration of cancer science with genome editing and related technologies
    Tetsushi Sakuma, Takashi Yamamoto · 2018 · Cancer Science
  50. Applications of CRISPR-Cas in Bioengineering, Biotechnology, and Translational Research
    Cia‐Hin Lau · 2018 · The CRISPR Journal
  51. Adenine base editing of the DUX4 polyadenylation signal for targeted genetic therapy in facioscapulohumeral muscular dystrophy
    Darina Šikrová, Vlad A. Cadar, Yavuz Ariyürek, Jeroen F. J. Laros, Judit Balog, Silvère M. van der Maarel · 2021 · Molecular Therapy — Nucleic Acids
  52. Next-generation T cell immunotherapies engineered with CRISPR base and prime editing: challenges and opportunities
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  53. Highly Efficient CRISPR-Mediated Base Editing in Sinorhizobium meliloti
    Longxiang Wang, Yuan Xiao, Xiaowei Wei, Jimin Pan, Deqiang Duanmu · 2021 · Frontiers in Microbiology
  54. CRISPR Screening: Molecular Tools for Studying Virus–Host Interactions
    Vladimir Chulanov, Anastasiya Kostyusheva, Sergey Brezgin, N. I. Ponomareva, Vladimir Gegechkori, Elena V. Volchkova, Пименов Николай Николаевич, Dmitry S. Kostyushev · 2021 · Viruses
  55. Genetically engineered zebrafish as models of skeletal development and regeneration
    Katrin Henke, D’Juan T. Farmer, Xubo Niu, Jessica M. Kraus, Jenna Lauren Galloway, Daniel W. Youngstrom · 2022 · Bone
  56. CRISPR/Cas9 as a New Antiviral Strategy for Treating Hepatitis Viral Infections
    Ulyana I. Bartosh, Anton S. Dome, Natalya V. Zhukova, Polina E. Karitskaya, Grigory A. Stepanov · 2023 · International Journal of Molecular Sciences
  57. Research progress of base editing and prime editing tools based on the CRISPR/Cas system
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  58. Development of a DNA double-strand break-free base editing tool in Corynebacterium glutamicum for genome editing and metabolic engineering
    Deng Chen, Xueqin Lv, Jianghua Li, Yanfeng Liu, Guocheng Du, Long Liu · 2020 · Metabolic Engineering Communications
  59. Progress and challenges in CRISPR-mediated therapeutic genome editing for monogenic diseases
    Colin T. Konishi, Chengzu Long · 2021 · Journal of Biomedical Research
  60. CRISPR/Cas9-Based Genome Editing Platform for Companilactobacillus crustorum to Reveal the Molecular Mechanism of Its Probiotic Properties
    Panpan Wang, Yanglei Yi, Xin Lü · 2021 · Journal of Agricultural and Food Chemistry
  61. Targeted dual base editing with Campylobacter jejuni Cas9 by single AAV-mediated delivery
    Jiyeon Kweon, An-Hee Jang, Eun‐Ji Kwon, Un Gi Kim, Ha Rim Shin, Ji-Eun See, Gayoung Jang, Chaeyeon Lee, Taeyoung Koo, Seokjoong Kim et al. · 2023 · Experimental & Molecular Medicine
  62. Advances in CRISPR/Cas gene therapy for inborn errors of immunity
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  63. GTR 2.0: gRNA-tRNA Array and Cas9-NG Based Genome Disruption and Single-Nucleotide Conversion in Saccharomyces cerevisiae
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  64. Emerging trends in transgene-free crop development: insights into genome editing and its regulatory overview
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  65. CRISPR-based oligo recombineering prioritizes apicomplexan cysteines for drug discovery
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  66. Double Selection Enhances the Efficiency of Target-AID and Cas9-Based Genome Editing in Yeast
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  67. Recent advances in functional genome analysis
    Roderic Guigó, Michiel de Hoon · 2018 · F1000Research
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  75. High-Fidelity Cytosine Base Editing in a GC-Rich Corynebacterium glutamicum with Reduced DNA Off-Target Editing Effects
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