Interleukin-1β Induces mtDNA Release to Activate Innate Immune Signaling via cGAS-STING

Aarreberg, Lauren D., Esser-Nobis, Katharina, Driscoll, Connor, Shuvarikov, Andrey, Roby, Justin A., Gale, Michael·2019·Molecular Cell

Cited by (328)

Items 301–328 of 328

  1. Biological Factors in Maintaining Joint Health
    Noah Knezic, Jacob Singer, Dane R.G. Lind, Ashley Groesbeck, Meredith Luhmann, Luis Lopez, Sara Robinson, Johnny Huard · 2025 · Springer eBooks
  2. Methylated urolithin a attenuates lipopolysaccharide-induced memory impairment and behavioral disorders by inhibiting mitochondrial inflammation through the Drp1/HK1/NLRP3 pathway
    Peng Chen, Wenhao Xiao, Fanzhao Zou, Jiexin Lei, Fuchao Chen, Ruhong Zhang · 2025 · Journal of Functional Foods
  3. Platelet-rich plasma mitigates lipopolysaccharide-driven acute lung injury by targeting the cGAS-induced STING/ERS/TBK1/IRF3/NF-κB pathway in male rats
    Fatma E. Hassan, Neamat Mahmoud Abd Elgilil, Basma Emad Aboulhoda, Hend Ahmed Abdallah, LailaA Rashed, Shimaa Magdy Shaban · 2025 · Histochemistry and Cell Biology
  4. Additional file 1 of Compound Bacillus alleviates diarrhea by regulating gut microbes, metabolites, and inflammatory responses in pet cats
    Wang, Fei, Xiaoying Mei, Wang, Qi, Pengwei Zhao, Zhou, Yuanhao, Li Tang, Wang, Baikui, Xu, Shujie, Xiang Li, Qian Jin et al. · 2023 · Figshare
  5. The mtDNA-cGAS-STING pathway: linking neuroinflammation and Alzheimer’s disease
    Guan-Lin HE, Ze-Bo HUANG, Guang LU · 2025 · Scientia Sinica Vitae
  6. Vaccines and Immune Response to Orthoflavivirus: Challenges and Advances
    Samantha Climaco-Arvizu, Mara Gutiérrez‐Sánchez · 2025 · IntechOpen eBooks
  7. The role of mitochondrial DNA-copy number in infectious disease: A bidirectional two-sample Mendelian randomization study
    Shuaijie Pei, Zhiwei Wang, Xiaofan Huang, Xiaoli Yu, Jianfeng Liu, Lin Zhu, Zhi Liang Ji, Yan Cui, Keliang Xie · 2026 · In Silico Research in Biomedicine
  8. The human and murine immune systems: regulated by dichotomous molecules
    Rafael Cardoso Maciel Costa Silva · 2026 · International Immunopharmacology
  9. Quantification and the effects of secondary colostrum components on neonatal calf physiology and metabolism: A scoping review
    E V Lopez-Bondarchuk, J.H.C. Costa · 2026 · Journal of Dairy Science
  10. Ethnopharmacological investigation of Fallopia dumetorum: anti-inflammatory activity and molecular mechanisms in human keratinocytes
    Young-Ju Do, So-Yeon Kim, Ye Eun Cho, So-Young Cho, Su Jung Lee, Ye-Won Lee, Seon-Woo Lee, Na-Hyun Lee, Sanghyun Lee, Ho Jung Bae et al. · 2026 · Journal of Ethnopharmacology
  11. Enterovirus A71 3AB protein facilitates immune evasion by blocking cGAS recognition of mtDNA
    Peng Sun, Xinya Yang, Jing Cui, Guicun Fang, Yuqin Wu, Jingyi Chang, Xiaofei Li, Y Q Xie, Lipeng Gan, Lina Ma et al. · 2026 · EMBO Reports
  12. cGAMP-VLP : optimization of production, functional studies, and development of a second generation
    Aurore Bochnakian · 2020
  13. Rôle de TRIM33 dans l'immunothérapie anti-tumorale radio-induite
    Anaïs Assouvie · 2021 · theses.fr (ABES)
  14. Micropterus salmoides rhabdovirus G protein interacts with VDAC to trigger mitochondrial DNA/cGAS-STING pathway-mediated antiviral immune responses
    Qiang Zhu, Xie Gu, Lijie Zhao, Zesheng Zhang, Mengmeng Huang, Hui Fei, Shun Yang · 2026 · Fish & Shellfish Immunology
  15. Interferon-alpha selectively signals mitochondrial pore opening to allow mitochondrial RNA release in systemic lupus erythematosus: pathophysiological implications
    Chun‐Yao Huang, De‐Wei Wu, Li‐Feng Hung, Chien‐Hsiang Wu, Shue-Fen Luo, Shuk‐Man Ka, Ann Chen, Ling‐Jun Ho, Jenn‐Haung Lai · 2026 · Cell Communication and Signaling
  16. Spermine suppresses Salmonella -induced macrophage innate immune responses via inhibition of the cGAS-STING and TLR4 pathways
    X Wang, Mohua Liu, Xiaoya Qu, Jing Hou, Shukun Chen, Tianyuan Chang, Jiayue Li, Jinglei Xia, Xihui Shen, Yue Wang et al. · 2026 · mBio
  17. Dengue Virus Evasion of Host Innate Immunity
    Sonja M. Best, Eva Chebishev, Ana Fernández-Sesma · 2026 · Annual Review of Virology
  18. Endosymbiotic theory of aging revisited: Age-related leakage of mitochondrial dsDNA/RNA stimulates cytosolic nucleic acid sensors which remodel the immune network and promote the aging process
    Antero Salminen, Kai Kaarniranta, Anu Kauppinen · 2026 · Biogerontology
  19. IL‐19 Modulates Antiviral Immunity and Inflammation via IL‐20RB/STAT3/TRIM22 Signaling Pathway
    Xinyu Zhang, F Wu, Xinru Hu, Ziwen Song, Lisha Deng, Yu Liao, Minjuan Shi, Zirong Han, Lijie Wang, Sun Cg · 2026 · Journal of Medical Virology
  20. DRP1 lysine 616 lactylation exacerbates cerebral ischemia-reperfusion injury by activating the STING inflammatory pathway
    Xiaoqi Ma, Dan Xin, X W Li, Zhenhao Ying, Zifeng Li, Wenli Wang, Zhigang Mei, Jinwen Ge · 2026 · Cell Communication and Signaling
  21. DNA Sensing Pathways in Innate Immunity: Implications for Alzheimer’s Disease Progression and Therapy
    Chenmo Shi, Ye Liu, Yanli Zhu · 2026 · Molecular Neurobiology
  22. Endothelial RANK signaling triggers bone marrow inflammaging through IL-1β expression
    Yasuhiro Kobayashi, Rina Iwamoto, Takumi Takahashi, Masayoshi Ishida, Zhifeng He, Kohei Murakami, Tomoyo Hara, Byambasuren Ganbaatar, Hiroki Yamagami, Itsuro Endo et al. · 2026 · Research Square
  23. Necroptosis–senescence crosstalk in tubulointerstitial fibrosis: the mtDNA–cGAS–STING–PFKFB3 axis as a metabolic bridge
    Donghui Wang, Hongxiang Zheng, Xinyue Zhang, Chenghua Zhang, Dandan Zhao, Shuqi Min, Shenju Wang · 2026 · Frontiers in Medicine
  24. Endothelial RANK signaling triggers bone marrow inflammaging
    Yasuhiro Kobayashi, Rina Iwamoto, Takumi Takahashi, Masayoshi Ishida, Zhifeng He, Kohei Murakami, Tomoyo Hara, Byambasuren Ganbaatar, Hiroki Yamagami, Itsuro Endo et al. · 2026 · Research Square
  25. Leptin attenuates heat stress-induced mitoxyperilysis in porcine Sertoli cells by suppressing the mtDNA-cGAS-STING axis
    Ming Guo, Jinyang Zhang, Shanshan Gu, Yawen Gao, Zhendong Zhu, Tao Zhang, Hongzhao Lu, Jun Luo, Wenxian Zeng · 2026 · Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
  26. Mitochondria affect antibacterial immunity in cross talk with innate immune response molecules coded by genes of nuclear origin
    Argha Chakraborty, Aruna Pal, Manti Debnath, Jyoti Sahu, Abantika Pal, Joydeep Mukherjee, Rajarshi Samanta, Paresh Nath Chatterjee · 2026 · Frontiers in Immunology
  27. 10-Gingerol attenuates alcohol-induced colon injury by modulating IL-36R and downstream cGAS–STING signaling to suppress macrophage inflammation and ferroptosis
    Miao Li, Tian-Tian Wang, Yan-Ni Huang, Xinxin Wang, Hong-Zhang Wang, Xiaokui Huo, Yan Wang, Hui-Yi Lv, Yue Shang · 2026 · Journal of Ethnopharmacology
  28. Circulating cell-free mitochondrial DNA and inflammation in Charcot–Marie–Tooth 1A and Charcot–Marie–Tooth 2A
    Zhenyu Li, Yize Li, Ping Li, Zhiying Xie, Meng Yu, Jianwen Deng, He Lv, Wei Zhang, Zhaoxia Wang, Lingchao Meng et al. · 2026 · Molecular Immunology