Molecular Mechanisms Directing PRC2 Recruitment and H3K27 Methylation
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Items 301–400 of 613
- Oncogenic Truncations of ASXL1 Enhance a Motif for BRD4 ET-Domain BindingBurgess, Abigail E., Kleffmann, Torsten, Mace, Peter D. · 2021 · Journal of Molecular Biology
- Role of EZH2-mediated H3K27me3 in placental ADAM12-S expression: implications for fetoplacental growthYa-nan Zhu, Xiaowen Gan, Fan Pan, Xiaotian Ni, Leslie Myatt, Wangsheng Wang, Kang Sun · 2022 · BMC Medicine
- FUS reads histone H3K36me3 to regulate alternative polyadenylationJunqi Jia, Haonan Fan, Xinyi Wan, Yuan Fang, Zhuoning Li, Yin Tang, Yanjun Zhang, Jun Huang, Fang Dong · 2024 · Nucleic Acids Research
- The PRC2 complex epigenetically silences GATA4 to suppress cellular senescence and promote the progression of breast cancerWenqian Yu, Xiaona Lin, Shuai Leng, Yiming Hou, Zhiqiao Dang, Shishan Xue, Na Li, Fengquan Zhang · 2024 · Translational Oncology
- Disabling leading and lagging strand histone transmission results in parental histones loss and reduced cell plasticity and viabilityLeonie Kollenstart, Alva Biran, Nicolás Alcaraz, Nazaret Reverón-Gómez, Victor Solis‐Mezarino, Moritz Carl Völker-Albert, Fiona Jenkinson, Valentin Flury, Anja Groth · 2025 · Science Advances
- H3K27me3 and the PRC1-H2AK119ub pathway cooperatively maintain heterochromatin and transcriptional silencing after the loss of H3K9 methylationKei Fukuda, Chikako Shimura, Yoichi Shinkai · 2025 · Epigenetics & Chromatin
- PRC2 insufficiency causes p53-dependent dyserythropoiesis in myelodysplastic syndromeKazumasa Aoyama, Daisuke Shinoda, Emi Suzuki, Yaeko Nakajima‐Takagi, Motohiko Oshima, Shuhei Koide, Ola Rizq, Sha Si, Shiro Tara, Goro Sashida et al. · 2020 · Leukemia
- Differential requirement for the Polycomb repressor complex 2 in dendritic cell and tissue-resident myeloid cell homeostasisYifan Zhan, Yuxia Zhang, Shengbo Zhang, Hannah D. Coughlan, Pedro L. Baldoni, Nicolas Jacquelot, Wang H. J. Cao, Simon Preston, Cynthia Louis, Jai Rautela et al. · 2021 · Science Immunology
- Pancreas development and the Polycomb group protein complexesNiloufer P. Dumasia, Prasad S. Pethe · 2020 · Mechanisms of Development
- A Structural Perspective on Gene Repression by Polycomb Repressive Complex 2Xin Liu · 2020 · Sub-cellular biochemistry/Subcellular biochemistry
- lncRNA RBM5‐AS1 promotes cell proliferation and invasion by epigenetically silencing miR‐132/212 in hepatocellular carcinoma cellsJin‐Yong Mu, Xiu‐Jun Tian, Ying‐Jie Chen · 2021 · Cell Biology International
- Low complexity domains, condensates, and stem cell pluripotencyMunender Vodnala, Eun‐Bee Choi, Yick W. Fong · 2021 · World Journal of Stem Cells
- Long non-coding RNA HOTAIR regulates the stemness of breast cancer cells via activation of NF-κB signaling pathwayJiajia Wang, Xingzhu Liu, Ping Li, Junrong Wang, Yu Shu, Xinyu Zhong, Zhen Gao, Jingyi Yang, Yashuang Jiang, Geng Yang · 2022 · Research Square
- Methylation of histone H3 lysine 36 is a barrier for therapeutic interventions of head and neck squamous cell carcinomaLucas D. Caeiro, Yuichiro Nakata, Rodrigo L. Borges, Mengsheng Zha, Liliana Garcia-Martinez, Carolina P. Bañuelos, Stephanie Stransky, Tong Liu, Ho Lam Chan, John Brabson et al. · 2024 · Genes & Development
- Dominant-negative effects of Weaver syndrome-associated EZH2 variantsOrla Deevy, Jingjing Li, Craig Monger, Francesca Matrà, Ellen Tuck, Molly Davies, Mihaly Badonyi, Maeve Boyce, Emma J. Doyle, Karsten Hokamp et al. · 2025 · Genes & Development
- Epigenetic preparation of future gene induction kineticsXiong, Jun, Zhu, Bing · 2025 · Annual Review of Genetics
- Epigenetic reactivation of PEG3 by EZH2 inhibitors suppresses renal clear cell carcinoma progressTeng Qiu, Yuanyuan Ding, Jingting Qin, Dexu Ren, Mengru Xie, Qilan Qian, Yasong Wang, Ling Ma, Aixin Jing, Jiayan Yang et al. · 2023 · Cellular Signalling
- Epigenetic regulation of hepatocellular carcinoma progression: MicroRNAs as therapeutic, diagnostic and prognostic factorsMehrdad Hashemi, Pouria Daneii, Mahya Asadalizadeh, Kiana Tabari, Arash Matinahmadi, Seyed Shahabadin Bidoki, Yasamin Sadat Mousavi Motlagh, Ali Moghadas Jafari, Amin Ghorbani, Amir Dehghanpour et al. · 2024 · The International Journal of Biochemistry & Cell Biology
- Unveiling the therapeutic potential of IHMT-337 in glioma treatment: targeting the EZH2-SLC12A5 axisHongwei Zhang, Zixuan Wang, Xiaolong Qiao, Nan Peng, Jiaxing Wu, Yinan Chen, Chuandong Cheng · 2024 · Molecular Medicine
- scRNA-seq revealed transcriptional signatures of human umbilical cord primitive stem cells and their germ lineage origin regulated by imprinted genesJustyna Jarczak, Kamila Bujko, Mariusz Z. Ratajczak, Magda Kucia · 2024 · Scientific Reports
- Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradationsYanping Zeng, Jian Xiao, Li Shi, Yangsha Li, Yuanxin Xu, Jiayun Zhou, Xiao Dong, Haiyang Hou, Chao Zhong, Gang Cheng et al. · 2025 · European Journal of Medicinal Chemistry
- PRC1 and PRC2 proximal interactome in mouse embryonic stem cellsDick W. Zijlmans, Suzan Stelloo, Danique J. C. Bax, Yavor Yordanov, Pien Toebosch, Maximilian W.D. Raas, Sigrid Verhelst, Lieke A. Lamers, Marijke P. A. Baltissen, Pascal W.T.C. Jansen et al. · 2025 · Cell Reports
- An evolving landscape of PRC2–RNA interactions in chromatin regulationRodrigo Aguilar, Michael Rosenberg, Vered Levy, Jeannie T. Lee · 2025 · Nature Reviews Molecular Cell Biology
- The Role of Methylation Modification in Neural Injury and RepairSaizhen Lv, Yanyu Pan, Tiemei Zheng, Qianqian Cao, Bin Yu, Feng‐Quan Zhou, Dong Wang · 2025 · International Journal of Molecular Sciences
- RNA-induced PRC2 inhibition depends on the sequence of bound RNAJiarui Song, Liqi Yao, Anne R. Gooding, Valentin Thron, Wayne O. Hemphill, Karen J. Goodrich, Annette H. Erbse, Vignesh Kasinath, Thomas R. Cech · 2026 · Nature Communications
- Histone Methylation Is Required for Virulence, Conidiation, and Multi-Stress Resistance of Alternaria alternataShuai Meng, Suya Huang, Jinhua Liu, Yunpeng Gai, Min Li, Shuo Duan, Shuting Zhang, Xuepeng Sun, Qi Yang, Yuchun Wang et al. · 2022 · Frontiers in Microbiology
- PHF1 compartmentalizes PRC2 via phase separationGenzhe Lu, Pilong Li · 2023 · Biochemical Journal
- An oligodendrocyte silencer element underlies the pathogenic impact of lamin B1 structural variantsBruce Nmezi, Guillermo Rodríguez Bey, Talia DeFrancesco Oranburg, Kseniia Dudnyk, Santana M. Lardo, Nathan Herdman, Anastasia M. Jacko, Sandy Rubio, Emanuel Loeza‐Alcocer, Julia Kofler et al. · 2025 · Nature Communications
- Depletion of Demethylase KDM6 Enhances Early Neuroectoderm Commitment of Human PSCsYajing Meng, Tianzhe Zhang, Ran Zheng, Song Ding, Jie Yang, Ran Liu, Yingan Jiang, Wei Jiang · 2021 · Frontiers in Cell and Developmental Biology
- Structural insights into the interactions of Polycomb Repressive Complex 2 with chromatinAkhil Gargey, Liqi Yao, Vignesh Kasinath · 2021 · Biochemical Society Transactions
- Abnormally elevated EZH2-mediated H3K27me3 enhances osteogenesis in aortic valve interstitial cells by inhibiting SOCS3 expressionKaiji Xie, Jingxin Zeng, Liming Wen, Xin Peng, Zhibin Lin, Gaopeng Xian, Yuyang Guo, Xi Yang, Peixin Li, Dingli Xu et al. · 2022 · Atherosclerosis
- Epigenomic machinery regulating pediatric AML: Clonal expansion mechanisms, therapies, and future perspectivesUgo Chianese, Chiara Papulino, Wout Megchelenbrink, Francesco Paolo Tambaro, Fortunato Ciardiello, Rosaria Benedetti, Lucia Altucci · 2023 · Seminars in Cancer Biology
- DOT1L interaction partner AF10 controls patterning of H3K79 methylation and RNA polymerase II to maintain cell identityCoral K. Wille, Edwin N. Neumann, Aniruddha J. Deshpande, Rupa Sridharan · 2023 · Stem Cell Reports
- Emerging interactions between RNA methylation and chromatin architectureAmber Louwagie, Ly Vu · 2024 · Current Opinion in Genetics & Development
- Epigenetic targets and their inhibitors in the treatment of idiopathic pulmonary fibrosisXiaohui Miao, Pan Liu, Yangyang Liu, Wenying Zhang, Chunxin Li, Xiujiang Wang · 2025 · European Journal of Medicinal Chemistry
- Structural mechanism of H3K27 demethylation and crosstalk with heterochromatin markersChien-Chu Lin, Yani Zhao, Caroline A. Foley, Aspen T. Hawkins, Lindsey Ingerman James, Stephen V. Frye, Robert K. McGinty · 2025 · Molecular Cell
- High throughput identification of genetic regulators of microglial inflammatory processes in Alzheimer's diseaseChristopher L. Cardona, Lai Wei, Joonwon Kim, Ellen Angeles, Gunjandeep Singh, Shiye Chen, Ronak Patel, Nkechime Ifediora, Peter Canoll, Andrew F. Teich et al. · 2025 · Journal of Neuroinflammation
- Role of EZH2 in adipogenesis and obesity: Current state of the art and implications – A reviewHaixia Wang · 2022 · Medicine
- A cis-regulatory module underlies retinal ganglion cell genesis and axonogenesisKamakshi Mehta, Marwa Daghsni, Reza Raeisossadati, Zhongli Xu, Emily Davis, Abigail Naidich, Bingjie Wang, Shiyue Tao, Shaohua Pi, Wei Chen et al. · 2024 · Cell Reports
- WTAP-dependent N6-methyladenosine methylation of lncRNA TEX41 promotes renal cell carcinoma progressionZhenwei Zhou, Xianjiong Chen, Huan Wang, Lifeng Ding, Mingchao Wang, Gonghui Li, Liqun Xia · 2024 · Scientific Reports
- Heterochromatin and Polycomb as regulators of haematopoiesisChristine R. Keenan · 2021 · Biochemical Society Transactions
- Getting under the skin of Polycomb-dependent gene regulationNeil P. Blackledge, Robert J. Klose · 2021 · Genes & Development
- Cyclohexene oxide CA, a derivative of zeylenone, exhibits anti-cancer activity in glioblastoma by inducing G0/G1 phase arrest through interference with EZH2Rui Jun Su, Weiwei Cao, Guoxu Ma, Weiping Li, Zongyang Li, Yongpei Liu, Lei Chen, Zebin Chen, Xuejuan Li, Ping Cui et al. · 2024 · Frontiers in Pharmacology
- The dual functionality of EZH2 in cardiovascular disease: Bridging cancer biology and cardiac pathophysiology through epigenetic regulation, metabolic reprogramming, and novel therapeutic interventionsShengwei Fang, Faris Alrumaihi, Wanian M Alwanian, Hajed Obaid Alharbi, Nujud Ahmed Alnughymishi, Somayah Mohammad Alfifi, Elizabeth S. Bennett, Peipei Zhang · 2025 · Current Problems in Cardiology
- Niche-specific epigenetic interventions in the spatially heterogeneous glioblastoma microenvironmental landscape: strategies for radiotherapy enhancementJunjie Wang, Kunjie Li, Yongzhe Wang, Junyi Zhang, Xin Peng, Ning Ji · 2025 · Frontiers in Molecular Biosciences
- Knockdown of NIR Suppresses Breast Cancer Cell Proliferation via Promoting FOXO3Bolin Chen, Chengcheng Dong, Fang Wang, Jiacai Wu · 2021 · OncoTargets and Therapy
- H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programsBrian Krug, Bo Hu, Haifeng Chen, Claudia Negrón-Lomas, Xiao Chen, Ahmed El Mouatani, Kristjan H. Gretarsson, Adam Ptack, Shriya Deshmukh, Nisha Kabir et al. · 2026 · Nature Genetics
- Recent research progress of circular RNAs in hepatocellular carcinomaZhi-di Li, Yang-ling Li, Jing Lu, Shang Liang, Chong Zhang, Linghui Zeng · 2024 · Frontiers in Oncology
- Transcriptionally active chromatin loops contain both ‘active’ and ‘inactive’ histone modifications that exhibit exclusivity at the level of nucleosome clustersStefan A. Koestler, Madeleine L. Ball, Leila Mureşan, Vineet Dinakaran, Robert A. White · 2024 · Epigenetics & Chromatin
- Epigenetic insights into Fragile X SyndromeLiangqun Xie, Huiying Li, MengLiang Xiao, Ningjing Chen, Xiaoxiao Zang, Yingying Liu, Hong Ye, Chaogang Tang · 2024 · Frontiers in Cell and Developmental Biology
- PRC2-RNA interactions: Viewpoint from Jimmy K. Guo, Mario R. Blanco, and Mitchell GuttmanJimmy K. Guo, Mario R. Blanco, Mitchell Guttman · 2024 · Molecular Cell
- PRC1 suppresses a female gene regulatory network to ensure testicular differentiationSo Maezawa, Masashi Yukawa, Kazuteru Hasegawa, Ryo Sugiyama, Mizuho Iizuka, Mengwen Hu, Akihiko Sakashita, Miguel Vidal, Haruhiko Koseki, Artem Barski et al. · 2023 · Cell Death and Disease
- Untangling the gordian knot: The intertwining interactions between developmental hormone signaling and epigenetic mechanisms in insectsBart Geens, Stijn Goossens, Jia Li, Yves Van de Peer, Jozef Vanden Broeck · 2024 · Molecular and Cellular Endocrinology
- Reduced Heterochromatin Formation on the pFAR4 Miniplasmid Allows Sustained Transgene Expression in the Mouse LiverMarie Pastor, Mickaël Quiviger, Julie Pailloux, Daniel Scherman, Corinne Marie · 2020 · Molecular Therapy — Nucleic Acids
- Epigenetic regulation of T cells by Polycomb group proteinsGuilherme A. Melo, Carolina Calôba, Gabrielle Brum, Thaís O Passos, Gustavo Martínez, Renata M. Pereira · 2022 · Journal of Leukocyte Biology
- Polycomb Repressive Complex 2: a Dimmer Switch of Gene Regulation in Calvarial Bone DevelopmentTimothy E Nehila, James W. Ferguson, Radhika P. Atit · 2020 · Current Osteoporosis Reports
- Human Telomerase Expression is under Direct Transcriptional Control of the Telomere-binding-factor TRF2Shalu Sharma, Ananda Kishore Mukherjee, Shuvra Shekhar Roy, Sulochana Bagri, Silje Lier, Meenakshi Verma, Antara Sengupta, Manish Kumar, Gaute Nesse, Deo Prakash Pandey et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Heterochromatin in the fungal plant pathogen, Zymoseptoria tritici: Control of transposable elements, genome plasticity and virulenceCallum J. Fraser, Simon K. Whitehall · 2022 · Frontiers in Genetics
- Maternal high fat diet induces circadian clock-independent endocrine alterations impacting the metabolism of the offspringLu Ding, Benjamin Dieter Weger, J. Y. Liu, Liyuan Zhou, Yenkai Lim, Dongmei Wang, Ziyan Xie, Jing Liu, Jing Ren, Jia Zheng et al. · 2024 · iScience
- Histone modifications in developmentYuhao Liu, Robert Schneider · 2025 · Development
- Safety and efficacy of HH2853, a novel EZH1/2 dual inhibitor, in patients with refractory solid tumours or non-Hodgkin lymphomas: a phase I studyZhengfu Fan, Jin Wang, Dan Liu, Lin Shen, Meiyu Fang, Patrick Johnson, Han Tun, David Sommerhalder, Jilong Yang, Yun Sik Yang et al. · 2025 · EClinicalMedicine
- Unraveling epigenetic drivers of immune evasion in gliomas: mechanisms and therapeutic implicationsDan Wu, Dongen Ju, Yujia Zhao, Wenna Liu, Qingqing Liu, Ying Jie Liang · 2025 · Frontiers in Immunology
- Epigenetic‑ncRNA crosstalk in atherosclerosis: Mechanisms, disease progression and therapeutic potential (Review)Ying Zhu, Zhixin Hu, Jianshuo Liu, Huaqing Duan, Jiqiang Zeng, Xiaosheng Li, Yang Tang, Ziling Song, Zhipeng Wu, Shanrong Zhang et al. · 2025 · International Journal of Molecular Medicine
- EZHIP restricts noncanonical PRC2 binding and regulates H3K27me3 intergenerational inheritance and reprogrammingYitian Zeng, Feng Kong, Zihan Xu, Xukun Lu, Qian Li, Bofeng Liu, Shu Liu, Lijun Dong, Ling Liu, Wenying Wang et al. · 2025 · Cell stem cell
- The Dynamics of Chromatin ReplicationLeonie Kollenstart, Sebastian Jespersen Charlton, Anja Groth · 2026 · Annual Review of Biochemistry
- Methylation patterns of Lys9 and Lys27 on histone H3 correlate with patient outcome and tumor progression in lung cancerYi Zhang, Bihui Zheng, Kexin Lou, Xinyu Xu, Youtao Xu · 2022 · Annals of Diagnostic Pathology
- SNIP1 and PRC2 coordinate cell fates of neural progenitors during brain developmentYurika Matsui, Mohamed Nadhir Djekidel, Katherine Lindsay, Parimal Samir, Nina Connolly, Gang Wu, Xiaoyang Yang, Yiping Fan, Beisi Xu, Jamy C. Peng · 2023 · Nature Communications
- Selective requirement for polycomb repressor complex 2 in the generation of specific hypothalamic neuronal subtypesBehzad Yaghmaeian Salmani, Brad Balderson, Susanne Bauer, Helen Ekman, Annika Starkenberg, Thomas Perlmann, Michael Piper, Mikael Bodén A, Stefan Thor · 2022 · Development
- Long non-coding RNAs - SNHG6 emerge as potential marker in colorectal cancerMichalina Jurkiewicz, Adrian Szczepaniak, Marta Zielińska · 2023 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
- Upregulated Long Non-Coding RNA LL22NC03-N64E9.1 Promotes the Proliferation and Migration of Human Breast Cancer Cells by Silencing Kruppel-Like Factor 2 ExpressionWeibin Lian, Xiaohua Jiang, Liangqiang Li, Qinglan Wang, Chengye Hong, Peidong Yang, Debo Chen · 2020 · Cancer Management and Research
- Structural classification of EZH2 inhibitors and prospects for the treatment of tumor: a reviewLing Yu, Ming-tao Xia, Youde Wang, Zhiwei Yan, Liying Zhang, Shuai Li · 2023 · Medicinal Chemistry Research
- Polycomb repression of Hox genes involves spatial feedback but not domain compaction or demixingSedona E. Murphy, Alistair Nicol Boettiger · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Sparse CBX2 nucleates many Polycomb proteins to promote facultative heterochromatinization of Polycomb target genesSteven Ingersoll, Abby Trouth, Xinlong Luo, Axel Espinoza, Joey Wen, Joseph C. Tucker, Kalkidan Astatike, Christopher J. Phiel, Tatiana G. Kutateladze, Tao Wu et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- USP17L promotes the 2-cell-like program through deubiquitination of H2AK119ub1 and ZSCAN4Panpan Shi, Xukun Lu, Kairang Jin, Linlin Liu, Guoxing Yin, Wenying Wang, Lijuan Wang, Lijuan Wang, Lijun Dong, Wei Xie et al. · 2025 · Nature Communications
- Epigenetic Dysregulation in Neurodegenerative Disease: Implications for Neuropathology and TherapyHussein Qasim, Karis Khattab, Mohammad Abu Shugaer, Giustino Varrassi · 2025 · Cureus
- Polycomb repressive complexes 1 and 2 independently and dynamically regulate euchromatin during cerebellar neurodevelopmentAditya Parmar, Anjali Srinivasan, Lena Krockenberger, Abijith Augustine, Owin Gong, Addison C. Bullard, Riya Kalra, Leya Ledvin, Dylan A. Pilz, Jonathan Tawil et al. · 2025 · PLoS Genetics
- PLETHORA transcription factors orchestrate epigenetic silencing of bivalent chromatin to promote root meristem development in riceQi Li, Junjie Li, Xintian Tang, Chen Chu, Jing Wang, Dao‐Xiu Zhou, Yu Zhao · 2025 · Molecular Plant
- Epigenetic enzyme inhibitors targeting DNA, histone, and RNA methylation: Mechanisms and therapeutic applications in cancerYiman Wang, Chen Ma, Xinya Liu, Junkai Cheng, Dan Zhu, Peng Liu, Peng Qi, Xiankai Li, Jian Gu, Qin Wang · 2026 · European Journal of Medicinal Chemistry
- Histone modification cross-talk: analytical tools and molecular mechanismsJennifer Jiang, Sarah E. DuBois-Coyne, Eunju Nam, Samuel D. Whedon, Kwangwoon Lee, Philip A. Cole · 2026 · Biochemical Journal
- H3F3A K27M Mutation Promotes the Infiltrative Growth of High-Grade Glioma in Adults by Activating β-Catenin/USP1 SignalingZhiyuan Sun, Yufu Zhu, Xia Feng, Xiaoyun Liu, Kunlin Zhou, Qing Wang, Hengzhu Zhang, Hengliang Shi · 2022 · Cancers
- Sequential deregulation of histone marks, chromatin accessibility and gene expression in response to PROTAC-induced degradation of ASH2LMirna Barsoum, Roksaneh Sayadi-Boroujeni, Alexander T. Stenzel, Philip Bussmann, Juliane Lüscher‐Firzlaff, Bernhard Lüscher · 2023 · Scientific Reports
- Covalent inhibitors meet epigenetics: New opportunitiesQiang Feng, Luoting Yu, Lu Li, Qiangsheng Zhang · 2024 · European Journal of Medicinal Chemistry
- Mutant EZH2 alters the epigenetic network and increases epigenetic heterogeneity in B cell lymphomaOfir Griess, Noa Furth, Nofar Harpaz, Nicoletta Di Bernardo, Tomer‐Meir Salame, Bareket Dassa, Ioannis Karagiannidis, Yusuke Isshiki, Menachem Gross, Ari M. Melnick et al. · 2025 · PLoS Biology
- Epigenetic Therapies in Endocrine-Related Cancers: Past Insights and Clinical ProgressDhruvika Varun, Maria Haque, Jorja Jackson-Oxley, Rachel Thompson, Amber A. Kumari, Corinne L. Woodcock, Anna E. Harris, Srinivasan Madhusudan, Emad A. Rakha, Catrin Sian Rutland et al. · 2025 · Cancers
- EZH2 functional dichotomy in reactive oxygen species-stratified glioblastomaLynnette Koh, Qing You Pang, Wisna Novera, See Wee Lim, Yuk Kien Chong, Jinyue Liu, Samantha Ya Lyn Ang, Ron Weng Yee Loh, Huilin Shao, Jianhong Ching et al. · 2024 · Neuro-Oncology
- Suppression of the H3K27me3 demethylase disrupts diapause formation in mosquito Culex pipiensXueyan Wei, Prabin Dhungana, Kaylah Callender, Berhanu W. Zewde, Fu Chen, Sung Joon Kim, Cheolho Sim · 2024 · Insect Biochemistry and Molecular Biology
- Molecular mechanisms underlying the evolution of a color polyphenism by genetic accommodation in the tobacco hornworm, Manduca sextaYuichiro Suzuki, Stephanie Amaya, Paula González, Daniela Becerril, Surisadai Aquit, Maya Davis, Madeline Hoesel, Elizabeth Chou, Hesper Khong, Kathryn Zaia et al. · 2025 · Proceedings of the National Academy of Sciences
- P14AS upregulates gene expression in the CDKN2A/2B locus through competitive binding to PcG protein CBX7Zhuoqi Li, Juanli Qiao, Wanru Ma, Jing Zhou, Liankun Gu, Dajun Deng, Baozhen Zhang · 2022 · Frontiers in Cell and Developmental Biology
- UTX inactivation in germinal center B cells promotes the development of multiple myeloma with extramedullary diseaseOla Rizq, Naoya Mimura, Motohiko Oshima, Shuji Momose, Naoya Takayama, Naoki Itokawa, Shuhei Koide, Asuka Shibamiya, Yurie Miyamoto‐Nagai, Mohamed Rizk et al. · 2023 · Leukemia
- Evidence that AGL17 is a significant downstream target of CLF in floral transition controlJie Shu, Chen Chen, Susanne E. Kohalmi, Yuhai Cui · 2020 · Plant Signaling & Behavior
- RNA closing the Polycomb circleIvano Mocavini, Luciano Di Croce · 2020 · Nature Genetics
- Sight restored by turning back the epigenetic clockAndrew D. Huberman · 2020 · Nature
- Development of Machine Learning Models for Accurately Predicting and Ranking the Activity of Lead Molecules to Inhibit PRC2 Dependent CancerMohd Danishuddin, Vikas Kumar, Shraddha Parate, Ashutosh Bahuguna, Gihwan Lee, Myeong Ok Kim, Keun Woo Lee · 2021 · Pharmaceuticals
- Zebrafish Polycomb repressive complex-2 critical roles are largely Ezh2- over Ezh1-driven and concentrate during early embryogenesisGabriel A. Yette, Scott Stewart, Kryn Stankunas · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Histone modification cross-talk and protein complex diversification confer plasticity to Polycomb repressionJacques Bonnet, Eva Triantopoulou, Jasmin Birnhäupl, Chenggang Lu, Margaret T. Fuller, Jürg Müller · 2025 · Genes & Development
- Histone modifications and depression: epigenetic mechanisms, therapeutic targets, and translational outlookLv, Liang-Zhen, Wang, Zhao-Di, Ren, Jia-jie, Li, Lu-Hao, Liu, Xian-bao, Li, Jia-li, Zhu, Hui, Jiang, Bei, Han, Ya-peng, Zhou, Xue-ming et al. · 2026 · Frontiers in Genetics
- Noncanonical association of EZH2 with E2F1 promotes tumor proliferation through chromatin remodelingMijoung Yoo, Hyeonji Lee, Hyorim Park, Byunghee Kang, Hyo‐Min Kim, Tae-Kyung Kim, Tae‐Young Roh · 2025 · Experimental & Molecular Medicine
- Changes in histone abundance and post-translational modifications in Rana [Lithobates] catesbeiana tissues during temperature-mediated thyroid hormone-induced metamorphosisHaley N. Kuecks-Winger, Anita A. Thambirajah, Lorissa M. Corrie, Caren C. Helbing · 2025 · Comparative Biochemistry and Physiology Part D Genomics and Proteomics
- CRISPR ‐Cas9 screen reveals that inhibition of enhancer of zeste homolog 2 sensitizes malignant T cells to dimethyl‐fumarate‐induced cell deathJan-Peter Teubner, Deniz Tümen, Arne Kandulski, Philipp Heumann, Patricia Mester, E Aschenbrenner, Kirstin Pollinger, Manuela Gunckel, Barbara Volz, Tobias Hein et al. · 2025 · FEBS Journal
- Epigenetics Role in Spermatozoa Function: Implications in Health and Evolution—An OverviewJulia Andreu-Noguera, Andrea López-Botella, Paula Sáez‐Espinosa, María José Gómez‐Torres · 2023 · Life