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Adrenomedullin 2.0: Adjusting Key Levers for Metabolic Stability

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Optimization of peptide-based polyagonists for treatment of diabetes and obesity

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Effect of palmitoylated prolactin-releasing peptide on food intake and neural activation after different routes of peripheral administration in rats

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Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist

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High metabolic in vivo stability and bioavailability of a palmitoylated ghrelin receptor ligand assessed by mass spectrometry

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Innovative chemical synthesis and conformational hints on the lipopeptide liraglutide

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Structure–Stability–Function Mechanistic Links in the Anti-Measles Virus Action of Tocopherol-Derivatized Peptide Nanoparticles

Figueira, T. N., Mendonça, D. A., Gaspar, D., Melo, M. N., Moscona, A., Porotto, M., Castanho, M. A. R. B., & Veiga, A. S. (2018) · ACS Nano · doi:10.1021/acsnano.8b01422 · Cited by 19 · see citing works

Design of novel Xenopus GLP-1-based dual glucagon-like peptide 1 (GLP-1)/glucagon receptor agonists

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Artificial peptides to induce membrane denaturation and disruption and modulate membrane composition and fusion

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Emerging roles of oxyntomodulin-based glucagon-like peptide-1/glucagon co-agonist analogs in diabetes and obesity

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The Structural Refinement of Glucagon for Therapeutic Use.

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High-Throughput Screening for Colloidal Stability of Peptide Formulations Using Dynamic and Static Light Scattering

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Peptides for biopharmaceutical applications

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Solid‐Phase Thiol–Ene Lipidation of Peptides for the Synthesis of a Potent CGRP Receptor Antagonist

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Prolonging parathyroid hormone analog action in vitro and in vivo through peptide lipidation

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Development of Peptide Biopharmaceuticals in Russia

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Vasoactive Intestinal Peptide Amphiphile Micelle Chemical Structure and Hydrophobic Domain Influence Immunomodulatory Potentiation

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Discovery of MK-1462: GLP-1 and Glucagon Receptor Dual Agonist for the Treatment of Obesity and Diabetes

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Design, structure of amphiphilic peptide and its application from single molecule to nanoparticle

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Glutamic acid-based dendritic peptides for scaffold-free cartilage tissue engineering

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Peptides Derived from Vascular Endothelial Growth Factor B Show Potent Binding to Neuropilin‐1

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Antimicrobial Activity of Silver Nanoparticles Loaded Biomimetic Isomeric Short Lipopeptide Nanostructures

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Self-Assembly of Exendin-4-Derived Dual Peptide Agonists is Mediated by Acylation and Correlated to the Length of Conjugated Fatty Acyl Chains

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Insulin fibrillation under physicochemical parameters of bioprocessing and intervention by peptides and surface-active agents

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Peptides for therapeutic applications – challenges and chances

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Late-stage lipidation of fully elaborated tryptophan-containing peptides for improved pharmacokinetics

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Lipopeptides as Therapeutics: Applications and In Vivo Quantitative Analysis

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Design of stapled oxyntomodulin analogs containing functionalized biphenyl cross-linkers

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NMR Assisted Antimicrobial Peptide Designing: Structure Based Modifications and Functional Correlation of a Designed Peptide VG16KRKP

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A Spectroscopic and Molecular Dynamics Study on the Aggregation Properties of a Lipopeptide Analogue of Liraglutide, a Therapeutic Peptide against Diabetes Type 2

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Novel Therapies for Cardiometabolic Disease: Recent Findings in Studies with Hormone Peptide-Derived G Protein Coupled Receptor Agonists

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A Survey and Guide to the Development of Fatty Acid‐derivatized Peptide Therapeutics

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Design of a novel long-acting insulin analogs by acetylation modification and compared with insulin Icodec

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Cyclic Peptides in Modern Drug Discovery: Trends and Therapeutic Directions

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Charakterystyka peptydów przeciwdrobnoustrojowych oraz wpływ modyfikacji chemicznych na modulowanie ich aktywności biologicznej

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Discovery of a Long-Acting Parathyroid Hormone 1–34 Analogue to Treat Hypoparathyroidism

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PACAP sequence modifications modulate the peptide antimicrobial activity against bacterial pathogens affecting aquaculture

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Evolution of Peptide Biopharmaceuticals

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Design and Biosynthesis of Ornithine 8-Containing Semaglutide Variants with a Click Chemistry-Modifiable Position 26

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Therapeutic Peptides: Unravelling Conformational Dynamics by Systematic Application of Biophysical Techniques

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Peripheral administration of lipidized NPAF and NPFF analogs does not influence central food intake regulation but induces anxiety-like behavior

Strnadová, V., Morgan, A., Škrlová, M., Haasová, E., Bardová, K., Myšková, A., Sýkora, D., Kuneš, J., Železná, B., & Maletı́nská, L. (2024) · Neuropeptides · doi:10.1016/j.npep.2024.102417 · Cited by 3 · see citing works

Max Bergmann award lecture:Macromolecular medicinal chemistry as applied to metabolic diseases

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Evolution of Peptide Drug Biopharmaceutics

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Fatty Acid Derivatization and Cyclization of the Immunomodulatory Peptide RP-182 Targeting CD206high Macrophages Improve Antitumor Activity

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Lipidation Effect on Surface Adsorption and Associated Fibrillation of the Model Protein Insulin

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Application of N-Dodecyl l-Peptide to Enhance Serum Stability while Maintaining Inhibitory Effects on Myometrial Contractions Ex Vivo

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Structural Dynamics of GLP-1 Analogues: Folding Energetics, Lipidation-Driven Assembly, and Aggregation Mechanisms

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A Facile Procedure for One-Pot Stable Conjugation of Two Proglucagon Cysteine-Containing Peptide Analogs

He, R., Mowery, S. A., Chabenne, J. R., Finan, B., Mayer, J. P., & DiMarchi, R. D. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.693958 · Cited by 1 · see citing works

Molecular Imaging Agent Design for Quantifying Beta Cell Mass in Type 1 Diabetes

Zhang, L. (2017) · Deep Blue (University of Michigan)

Hitting "Undruggable" Targets: Determining the Properties of Cell Penetrant Stabilized Peptide Therapeutics for Intracellular Targets

Atangcho, L. (2020) · Deep Blue (University of Michigan)

Development and Exploitation of RiPPs technology for Peptide Engineering

Xu, Y. (2024) · doi:10.33612/diss.1161821388

Chemistry and sources of protein

Kumar, V., Ragaza, J. A., & Glencross, B. D. (2025) · Elsevier eBooks · doi:10.1016/b978-0-323-90873-3.00017-8

Incorporation of D-amino Acids and Ornithines into Tirzepatide by Biosynthesis in E. Coli

Xu, Y., Fu, Y., & Kuipers, O. P. (2026) · International Journal of Peptide Research and Therapeutics · doi:10.1007/s10989-026-10813-7

Chemical dialogues at the peanut root microbiome interface orchestrate microbial signaling networks

Gelaye, Y. (2026) · Discover Agriculture · doi:10.1007/s44279-026-00584-6

Lipidated peptides and the limits of chemical control

Roque‐Borda, C. A., Sharma, A., Pavan, F. R., de la Torre, B. G., & Alberício, F. (2026) · Frontiers in Chemistry · doi:10.3389/fchem.2026.1807712

Innovative use of fatty acid acylation to enhance biological action and biophysical properties of peptide therapeutics

Ward, B. P. (2012) · ProQuest Demo Repository

Lipidation and conformational constraining for prolonging the effects of peptides: Xenopus glucagon-like peptide 1 analogues with potent and long-acting hypoglycemic activity

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Effect of Lipidation on the Structure, Oligomerization, and Aggregation of Glucagon-like Peptide 1

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Neoglycolipids for Prolonging the Effects of Peptides: Self-Assembling Glucagon-like Peptide 1 Analogues with Albumin Binding Properties and Potent in Vivo Efficacy

van Witteloostuijn, S. B., Mannerstedt, K., Wismann, P., Bech, E. M., Thygesen, M. B., Vrang, N., Jelsing, J., Jensen, K. J., & Pedersen, S. L. (2016) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.6b00787 · Cited by 33 · see citing works

Molecular design of peptide therapeutics via N-terminal modification

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