The DOI matches its Crossref record; 111 of the 111 references it cites were found in a registry or an index.
Osteopontin: A novel regulator at the cross roads of inflammation, obesity and diabetes
Open accessAbstract
Since its first description more than 20 years ago osteopontin has emerged as an active player in many physiological and pathological processes, including biomineralization, tissue remodeling and inflammation. As an extracellular matrix protein and proinflammatory cytokine osteopontin is thought to facilitate the recruitment of monocytes/macrophages and to mediate cytokine secretion in leukocytes. Modulation of immune cell response by osteopontin has been associated with various inflammatory diseases and may play a pivotal role in the development of adipose tissue inflammation and insulin resistance. Here we summarize recent findings on the role of osteopontin in metabolic disorders, particularly focusing on diabetes and obesity.
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1 retracted
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RetractedReciprocal regulation of inflammation and lipid metabolism by liver X receptors
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Cited by
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Immunologic and endocrine functions of adipose tissue: implications for kidney disease
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Impact of Phosphorus-Based Food Additives on Bone and Mineral Metabolism
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Zonation in NASH – A key paradigm for understanding pathophysiology and clinical outcomes
Steinman, J. B., Salomao, M. A., & Pajvani, U. B. (2021) · Liver International · doi:10.1111/liv.15025 · Cited by 49
Metadata
- Authors
- Kahles, F., Findeisen, H. M., & Bruemmer, D.
- Venue
- Molecular Metabolism
- Publisher
- Elsevier BV
- Published
- 2014-07
- Volume
- 3
- Issue
- 4
- Pages
- 384-393
- ISSN
- 2212-8778 (ISSN-L)
- OpenAlex
- W2025628030
- Cited by
- 408
- References
- 111
- FWCI
- 19.77
- Type
- journal article
- Language
- en
- Open access
- gold
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- CoChat. (2026). Citation check: Osteopontin: A novel regulator at the cross roads of inflammation, obesity and diabetes. https://app.cochat.ai/papers/10.1016/j.molmet.2014.03.004
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- Kahles, F., Findeisen, H. M., & Bruemmer, D. (2014). Osteopontin: A novel regulator at the cross roads of inflammation, obesity and diabetes. Molecular Metabolism. https://doi.org/10.1016/j.molmet.2014.03.004
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
