A strategy to discover genes that carry multi-allelic or mono-allelic risk for common diseases: A cohort allelic sums test (CAST)

Morgenthaler, Stephan, Thilly, William G.·2007·Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Cited by (508)

Items 101–200 of 508

  1. The impact of a fine-scale population stratification on rare variant association test results
    Elodie Persyn, Richard Redon, Lise Bellanger, Christian Dina C · 2018 · PLoS ONE
  2. Multi-trait analysis of rare-variant association summary statistics using MTAR
    Lan Luo, Judong Shen, Hong Zhang, Aparna Chhibber, Devan V. Mehrotra, Zheng-Zheng Tang · 2020 · Nature Communications
  3. Calibrated rare variant genetic risk scores for complex disease prediction using large exome sequence repositories
    Ricky Lali, Michael Chong, Arghavan Omidi, Pedrum Mohammadi‐Shemirani, Ann Le, Edward Cui, Guillaume Paré · 2021 · Nature Communications
  4. Marbled Inflation From Population Structure in Gene‐Based Association Studies With Rare Variants
    Qianying Liu, Dan L. Nicolae, Lin Chen · 2013 · Genetic Epidemiology
  5. Whole Exome Sequencing Identifies Novel Genes for Fetal Hemoglobin Response to Hydroxyurea in Children with Sickle Cell Anemia
    Vivien Sheehan, Jacy R. Crosby, Aniko Sabo, Nicole A. Mortier, Thad A. Howard, Donna Marie Muzny, Shannon Dugan, Banu Aygün, Kerri A. Nottage, Eric Boerwinkle et al. · 2014 · PLoS ONE
  6. Joint Analysis of Multiple Traits Using "Optimal" Maximum Heritability Test
    Zhenchuan Wang, Qiuying Sha, Shuanglin Zhang · 2016 · PLoS ONE
  7. Powerful extreme phenotype sampling designs and score tests for genetic association studies
    Thea Bjørnland, Anja Bye, Einar Ryeng, Ulrik Wisløff, Mette Langaas · 2018 · Statistics in Medicine
  8. Detecting adaptive trait loci in nonmodel systems: divergence or admixture mapping?
    Jacob E. Crawford, Rasmus Nielsen · 2013 · Molecular Ecology
  9. A Genetic Signature of Spina Bifida Risk from Pathway-Informed Comprehensive Gene-Variant Analysis
    Nicholas J. Marini, Thomas J. Hoffmann, Edward J. Lammer, Jill Hardin, Katherine D. Lazaruk, Jason B. Stein, Dennis A. Gilbert, Crystal Wright, Anna Lipzen, Len A. Pennacchio et al. · 2011 · PLoS ONE
  10. Linkage disequilibrium clustering‐based approach for association mapping with tightly linked genomewide data
    Zitong Li, Petri Kemppainen, Pasi M. A. Rastas, Juha Merilä · 2018 · Molecular Ecology Resources
  11. Aggregation of rare/low-frequency variants of the mitochondria respiratory chain-related proteins in rheumatoid arthritis patients
    Shigeki Mitsunaga, Kazuyoshi Hosomichi, Yuko Okudaira, Hirofumi Nakaoka, Yasuo Suzuki, Masataka Kuwana, Shinji Sato, Yuko Kaneko, Yasuhiko Homma, Akira Oka et al. · 2015 · Journal of Human Genetics
  12. Segregation of LIPG, CETP, and GALNT2 Mutations in Caucasian Families with Extremely High HDL Cholesterol
    Ian Tietjen, G. Kees Hovingh, Roshni Rebecca Singaraja, Chris Radomski, Amina Barhdadi, Jason McEwen, Elden Chan, Maryanne Mattice, Annick Legendre, Patrick L. Franchini et al. · 2012 · PLoS ONE
  13. A review of kernel methods for genetic association studies
    Nicholas Bradley Larson, Jun Chen, Daniel J. Schaid · 2019 · Genetic Epidemiology
  14. Likelihood Ratio Tests in Rare Variant Detection for Continuous Phenotypes
    Ping Zeng, Yang Zhao, Jin Liu, Liya Liu, Liwei Zhang, Ting Wang, Shuiping Huang, Feng Chen · 2014 · Annals of Human Genetics
  15. The power of regional heritability analysis for rare and common variant detection: simulations and application to eye biometrical traits
    Yoshinobu Uemoto, Ricardo Pong‐Wong, Pau Navarro, Véronique Vitart, Caroline Hayward, James F. Wilson, Igor Rudan, Harry J. Campbell, Nicholas Dixon Hastie, Alan F. Wright et al. · 2013 · Frontiers in Genetics
  16. Rare variants in TMEM132D in a case–control sample for panic disorder
    Carina Quast, André Altmann, Peter C Weber, Janine Arloth, Daniel M. Bader, Angela Heck, Hildegard Pfister, Bertram Müller‐Myhsok, Angelika Erhardt, Elisabeth B. Binder · 2012 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
  17. Generalized Functional Linear Models for Gene‐Based Case‐Control Association Studies
    Ruzong Fan, Yifan Wang, James L. Mills, Tonia C. Carter, Iryna V. Lobach, Alexander F. Wilson, Joan Wilson, Daniel E. Weeks, Momiao Xiong · 2014 · Genetic Epidemiology
  18. Genome‐Wide Association Analysis of Imputed Rare Variants: Application to Seven Common Complex Diseases
    Reedik Mägi, Jennifer L. Asimit, Aaron Day-Williams, Eleftheria Zeggini, Andrew P. Morris · 2012 · Genetic Epidemiology
  19. Power of Family‐Based Association Designs to Detect Rare Variants in Large Pedigrees Using Imputed Genotypes
    Mohamad Saad, Ellen M. Wijsman · 2013 · Genetic Epidemiology
  20. Meta-Analysis of Sequencing Studies With Heterogeneous Genetic Associations
    Zheng-Zheng Tang, Dan-Yu Lin · 2014 · Genetic Epidemiology
  21. A powerful test for multiple rare variants association studies that incorporates sequencing qualities
    Zhongyin John Daye, Hongzhe Li, Zhi Wei · 2012 · Nucleic Acids Research
  22. Testing Rare-Variant Association without Calling Genotypes Allows for Systematic Differences in Sequencing between Cases and Controls
    Yi‐Juan Hu, Peizhou Liao, H. Richard Johnston, Andrew S. Allen, Glen A. Satten · 2016 · PLoS Genetics
  23. Analysis of mutational spectra by denaturing capillary electrophoresis
    Per Olaf Ekstrøm, Konstantin Khrapko, Xiaocheng Li-Sucholeiki, Ian W. Hunter, William G. Thilly · 2008 · Nature Protocols
  24. Confounded by sequencing depth in association studies of rare alleles
    Chad P. Garner · 2011 · Genetic Epidemiology
  25. Identification of rare coding variants in TYK2 protective for rheumatoid arthritis in the Japanese population and their effects on cytokine signalling
    Tomoki Motegi, Yuta Kochi, Koichi Matsuda, Michiaki Kubo, Kazuhiko Yamamoto, Yukihide Momozawa · 2019 · Annals of the Rheumatic Diseases
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  27. On Efficient and Accurate Calculation of Significance P ‐Values for Sequence Kernel Association Testing of Variant Set
    Baolin Wu, Weihua Guan, James S. Pankow · 2016 · Annals of Human Genetics
  28. A simple and accurate method to determine genomewide significance for association tests in sequencing studies
    Danyu Y. Lin · 2019 · Genetic Epidemiology
  29. Evaluation of Gene-Based Family-Based Methods to Detect Novel Genes Associated With Familial Late Onset Alzheimer Disease
    María Victoria Fernández, John Budde, Jorge L. Del‐Aguila, Laura Ibáñez, Yuetiva K. Deming, Oscar Harari, Joanne B. Norton, John C. Morris, Alison Goate, NIA-LOAD family study group et al. · 2018 · Frontiers in Neuroscience
  30. Specificity, length and luck drive gene rankings in association studies
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    Qi Yan, Hemant K. Tiwari, Nengjun Yi, Guimin Gao, Kui Zhang, Wan‐Yu Lin, Xiang‐Yang Lou, Xiangqin Cui, Nianjun Liu · 2015 · Human Heredity
  32. Assessing multivariate gene-metabolome associations with rare variants using Bayesian reduced rank regression
    Pekka Marttinen, Matti Pirinen, Antti‐Pekka Sarin, Jussi Gillberg, Johannes Kettunen, Ida L. Surakka, Antti J. Kangas, Pasi Soininen, Paul F. O’Reilly, Marika Kaakinen et al. · 2014 · Bioinformatics
  33. Strategies for Imputing and Analyzing Rare Variants in Association Studies
    Thomas J. Hoffmann, John S. Witte · 2015 · Trends in Genetics
  34. Rare variant association testing in the non-coding genome
    Ozvan Bocher, Emmanuelle Génin · 2020 · Human Genetics
  35. The contribution of rare genetic variants to the pathogenesis of polycystic ovary syndrome
    Matthew Dapas, Andrea Elizabeth Dunaif · 2020 · Current Opinion in Endocrine and Metabolic Research
  36. An allelic-series rare-variant association test for candidate-gene discovery
    Zachary Ryan McCaw, Colm T. O’Dushlaine, Hari Somineni, Michael D. Bereket, Christoph Klein, Theofanis Karaletsos, Francesco Paolo Casale, Daphne Koller, Thomas W. Soare · 2023 · The American Journal of Human Genetics
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    Valentina Cipriani, Letizia Vestito, Emma Forton Magavern, Julius O.B. Jacobsen, Gavin Arno, Elijah Raphael Behr, Katherine Angela Benson, Marta Bértoli, Detlef Böckenhauer, Michael R. Bowl et al. · 2025 · Nature
  40. Rare variant association test with multiple phenotypes
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  41. Identification of Restless Legs Syndrome Genes by Mutational Load Analysis
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  42. Boosting the Power of the Sequence Kernel Association Test by Properly Estimating Its Null Distribution
    Kai Wang · 2016 · The American Journal of Human Genetics
  43. Computational Genomics in the Era of Precision Medicine: Applications to Variant Analysis and Gene Therapy
    Yung-Chun Wang, Yuchang Wu, Julie Y. Choi, Garrett Allington, Shujuan Zhao, Mariam Khanfar, Kuangying Yang, Po-Ying Fu, Max Wrubel, Xiaobing Yu et al. · 2022 · Journal of Personalized Medicine
  44. A Hybrid Likelihood Model for Sequence-Based Disease Association Studies
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  45. TARV: Tree-based Analysis of Rare Variants Identifying Risk Modifying Variants inCTNNA2andCNTNAP2for Alcohol Addiction
    Chi Song, Heping Zhang D · 2014 · Genetic Epidemiology
  46. Tagging SNP-set selection with maximum information based on linkage disequilibrium structure in genome-wide association studies
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  47. Two Adaptive Weighting Methods to Test for Rare Variant Associations in Family‐Based Designs
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  48. The Use of the Linear Mixed Model in Human Genetics
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  49. Real world scenarios in rare variant association analysis: the impact of imbalance and sample size on the power in silico
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  50. A genome-wide case-only test for the detection of digenic inheritance in human exomes
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  51. Integrating Rare-Variant Testing, Function Prediction, and Gene Network in Composite Resequencing-Based Genome-Wide Association Studies (CR-GWAS)
    Chengsong Zhu, Xianran Li, Jianming Yu · 2011 · G3 Genes Genomes Genetics
  52. A Fast and Noise‐Resilient Approach to Detect Rare‐Variant Associations With Deep Sequencing Data for Complex Disorders
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  53. Contribution of rare whole-genome sequencing variants to plasma protein levels and the missing heritability
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  55. Population‐based and family‐based designs to analyze rare variants in complex diseases
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  56. Genome-wide sequencing to identify the cause of hereditary cancer syndromes: With examples from familial pancreatic cancer
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  57. Methods for Collapsing Multiple Rare Variants in Whole‐Genome Sequence Data
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  58. Progress in methods for rare variant association
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  59. Imaging genetics — towards discovery neuroscience
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  60. ‘Location, Location, Location’: a spatial approach for rare variant analysis and an application to a study on non-syndromic cleft lip with or without cleft palate
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  62. Rare variant testing across methods and thresholds using the multi-kernel sequence kernel association test (MK-SKAT)
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  63. Blood lipid-related low-frequency variants in LDLR and PCSK9 are associated with onset age and risk of myocardial infarction in Japanese
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  64. A powerful and data‐adaptive test for rare‐variant–based gene‐environment interaction analysis
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  65. A Geometric Framework for Evaluating Rare Variant Tests of Association
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  66. Methodology for the analysis of rare genetic variation in genome-wide association and re-sequencing studies of complex human traits
    Loukas Moutsianas, Andrew P. Morris · 2014 · Briefings in Functional Genomics
  67. Incorporating Prior Biologic Information for High-Dimensional Rare Variant Association Studies
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  68. Detecting Low Frequent Loss-of-Function Alleles in Genome Wide Association Studies with Red Hair Color as Example
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  70. Digging into the extremes: a useful approach for the analysis of rare variants with continuous traits?
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  79. Functional Coding Variants in SLC6A15, a Possible Risk Gene for Major Depression
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