Folic acid conjugated capecitabine capped green synthesized fluorescent carbon dots as a targeted nano-delivery system for colorectal cancer

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R. L., Torre, L. A., & Jemal, A. (2018) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21492 · Cited by 84,109

Quantum-Sized Carbon Dots for Bright and Colorful Photoluminescence

Sun, Y., Zhou, B. Q., Lin, Y., Wang, W., Fernando, K. A. S., Pathak, P., Meziani, M. J., Harruff, B. A., Wang, X., Wang, H., et al. (2006) · Journal of the American Chemical Society · doi:10.1021/ja062677d · Cited by 5,130

Luminescent Carbon Nanodots: Emergent Nanolights

Baker, S. N., & Baker, G. A. (2010) · Angewandte Chemie International Edition · doi:10.1002/anie.200906623 · Cited by 4,985

Carbon nanodots: synthesis, properties and applications

Li, H., Kang, Z., Liu, Y., & Lee, S. (2012) · Journal of Materials Chemistry · doi:10.1039/c2jm34690g · Cited by 2,854

Carbon quantum dots: synthesis, properties and applications

Wang, Y., & Hu, A. (2014) · Journal of Materials Chemistry C · doi:10.1039/c4tc00988f · Cited by 2,607

Controlled drug delivery vehicles for cancer treatment and their performance

Senapati, S., Mahanta, A. K., Kumar, S., & Maiti, P. (2018) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-017-0004-3 · Cited by 2,167

Simple one-step synthesis of highly luminescent carbon dots from orange juice: application as excellent bio-imaging agents

Sahu, S., Behera, B., Maiti, T. K., & Mohapatra, S. (2012) · Chemical Communications · doi:10.1039/c2cc33796g · Cited by 1,822

Effect of Zeta Potential on the Properties of Nano-Drug Delivery Systems - A Review (Part 2)

Honary, S., & Zahir, F. (2013) · Tropical Journal of Pharmaceutical Research · doi:10.4314/tjpr.v12i2.20 · Cited by 1,310

Carbon dots: synthesis, formation mechanism, fluorescence origin and sensing applications

Liu, M. L., Chen, B., Li, C. M., & Huang, C. Z. (2019) · Green Chemistry · doi:10.1039/c8gc02736f · Cited by 1,275

Effect of Zeta Potential on the Properties of Nano-Drug Delivery Systems - A Review (Part 1)

Honary, S., & Zahir, F. (2013) · Tropical Journal of Pharmaceutical Research · doi:10.4314/tjpr.v12i2.19 · Cited by 1,144

Carbon dots: large-scale synthesis, sensing and bioimaging

Zhang, J., & Yu, S. (2015) · Materials Today · doi:10.1016/j.mattod.2015.11.008 · Cited by 736

Role of nanotechnology in targeted drug delivery and imaging: a concise review

Koo, O. M. Y., Rubinstein, I., & Önyüksel, H. (2005) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2005.06.004 · Cited by 718

Review of cancer from perspective of molecular

Hassanpour, S. H., & Dehghani, M. A. (2017) · Journal of Cancer Research and Practice · doi:10.1016/j.jcrpr.2017.07.001 · Cited by 688

Capecitabine: A review

Walko, C. M., & Lindley, C. M. (2005) · Clinical Therapeutics · doi:10.1016/j.clinthera.2005.01.005 · Cited by 679

Nanocarriers for cancer-targeted drug delivery

Kumari, P., Ghosh, B., & Biswas, S. (2015) · Journal of drug targeting · doi:10.3109/1061186x.2015.1051049 · Cited by 619

Green Synthesis of Luminescent Nitrogen-Doped Carbon Dots from Milk and Its Imaging Application

Wang, L., & Zhou, H. S. (2014) · Analytical Chemistry · doi:10.1021/ac502646x · Cited by 581

Microwave-assisted synthesis of carbon dots and their applications

de Medeiros, T. V., Manioudakis, J., Noun, F., Macairan, J., Victoria, F., & Naccache, R. (2019) · Journal of Materials Chemistry C · doi:10.1039/c9tc01640f · Cited by 521

Novel and green synthesis of high-fluorescent carbon dots originated from honey for sensing and imaging

Yang, X., Zhuo, Y., Zhu, S., Luo, Y., Feng, Y., & Dou, Y. (2014) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2014.04.046 · Cited by 483

Waste frying oil as a precursor for one-step synthesis of sulfur-doped carbon dots with pH-sensitive photoluminescence

Hu, Y., Yang, J. L., Tian, J., Li, J., & Yu, J. (2014) · Carbon · doi:10.1016/j.carbon.2014.05.081 · Cited by 411

Synthesis of Luminescent Carbon Dots with Ultrahigh Quantum Yield and Inherent Folate Receptor-Positive Cancer Cell Targetability

Liu, H., Li, Z., Sun, Y., Geng, X., Hu, Y., Meng, H., Ge, J., & Qu, L. (2018) · Scientific Reports · doi:10.1038/s41598-018-19373-3 · Cited by 327

Carbon dots as a trackable drug delivery carrier for localized cancer therapy in vivo

Zeng, Q., Shao, D., He, X., Ren, Z., Ji, W., Shan, C., Qu, S., Li, J., Chen, L., & Li, Q. (2016) · Journal of Materials Chemistry B · doi:10.1039/c6tb01259k · Cited by 292

Thermal treatment of hair for the synthesis of sustainable carbon quantum dots and the applications for sensing Hg2+

Guo, Y., Zhang, L., Cao, F., & Leng, Y. (2016) · Scientific Reports · doi:10.1038/srep35795 · Cited by 226

Simple Approach to Synthesize Amino-Functionalized Carbon Dots by Carbonization of Chitosan

Liu, X., Pang, J., Xu, F., & Zhang, X. (2016) · Scientific Reports · doi:10.1038/srep31100 · Cited by 221

Synthesis and formation mechanistic investigation of nitrogen-doped carbon dots with high quantum yields and yellowish-green fluorescence

Hou, J., Wang, W., Zhou, T., Wang, B., Li, H., & Ding, L. (2016) · Nanoscale · doi:10.1039/c6nr02701f · Cited by 220

On the Emission Properties of Carbon Dots: Reviewing Data and Discussing Models

Carbonaro, C. M., Corpino, R., Salis, M., Mocci, F., Thakkar, S. V., Olla, C., & Ricci, P. C. (2019) · C – Journal of Carbon Research · doi:10.3390/c5040060 · Cited by 204

Doxorubicin-loaded environmentally friendly carbon dots as a novel drug delivery system for nucleus targeted cancer therapy

Yuan, Y., Guo, B., Hao, L., Liu, N., Lin, Y., Guo, W., Li, X., & Gu, B. (2017) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2017.07.030 · Cited by 196

Swarming carbon dots for folic acid mediated delivery of doxorubicin and biological imaging.

Mewada, A., Pandey, S., Thakur, M., Jadhav, D., & Sharon, M. (2014) · Journal of materials chemistry. B · doi:10.1039/c3tb21436b · Cited by 186

A novel one-pot route for large-scale preparation of highly photoluminescent carbon quantum dots powders

Hou, J., Yan, J., Zhao, Q. R., Li, Y., Ding, H. Y., & Ding, L. (2013) · Nanoscale · doi:10.1039/c3nr03444e · Cited by 176

Folic acid-conjugated green luminescent carbon dots as a nanoprobe for identifying folate receptor-positive cancer cells

Zhang, J., Zhao, X., Xian, M., Dong, C., & Shuang, S. (2018) · Talanta · doi:10.1016/j.talanta.2018.02.009 · Cited by 158

Rational design of a minimalist nanoplatform to maximize immunotherapeutic efficacy: Four birds with one stone

Zhou, S., Shang, Q., Wang, N., Li, Q., Song, A., & Luan, Y. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.09.035 · Cited by 148

Targeted Nanoparticles for Cancer Therapy: Promises and Challenges

Nguyen, K. T. (2011) · Journal of Nanomedicine & Nanotechnology · doi:10.4172/2157-7439.1000103e · Cited by 139

Heteroatom doped blue luminescent carbon dots as a nano-probe for targeted cell labeling and anticancer drug delivery vehicle

Das, P., Ganguly, S., Agarwal, T., Maity, P. P., Ghosh, S., Choudhary, S., Gangopadhyay, S., Maiti, T. K., Dhara, S., Banerjee, S., et al. (2019) · Materials Chemistry and Physics · doi:10.1016/j.matchemphys.2019.121860 · Cited by 139

Folic acid-modified liposomal drug delivery strategy for tumor targeting of 5-fluorouracil

Moghimipour, E., Rezaei, M., Ramezani, Z., Kouchak, M., Amini, M., Angali, K. A., Dorkoosh, F. A., & Handali, S. (2017) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2017.12.011 · Cited by 122

A multianalyte fluorescent carbon dots sensing system constructed based on specific recognition of Fe( iii ) ions

Song, P., Zhang, L., Long, H., Meng, M., Liu, T., Yin, Y., & Xi, R. (2017) · RSC Advances · doi:10.1039/c7ra04122e · Cited by 118

Microwave-assisted and one-step synthesis of PEG passivated fluorescent carbon dots from gelatin as an efficient nanocarrier for methotrexate delivery

Arsalani, N., Nezhad‐Mokhtari, P., & Jabbari, E. (2019) · Artificial Cells Nanomedicine and Biotechnology · doi:10.1080/21691401.2018.1562460 · Cited by 112

Carbon quantum dots: A promising nanocarrier for bioimaging and drug delivery in cancer

Jana, P., & Dev, A. (2022) · Materials Today Communications · doi:10.1016/j.mtcomm.2022.104068 · Cited by 106

Chitosan-glucuronic acid conjugate coated mesoporous silica nanoparticles: A smart pH-responsive and receptor-targeted system for colorectal cancer therapy

Narayan, R., Gadag, S., Cheruku, S. P., Raichur, A. M., Day, C. M., Garg, S., Manandhar, S., Pai, K. S. R., Suresh, A., Mehta, C. H., et al. (2021) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2021.117893 · Cited by 103

Microwave-assisted polyol synthesis of carbon nitride dots from folic acid for cell imaging

Xue, M., Guan, W., Gu, W., Guo, C., Su, S., Xu, P., & Ye, L. (2014) · International Journal of Nanomedicine · doi:10.2147/ijn.s68575 · Cited by 78

Capecitabine encapsulated chitosan succinate-sodium alginate macromolecular complex beads for colon cancer targeted delivery: in vitro evaluation

Sinha, P., Ubaidulla, U., Rathnam, G., Ganesh, M., & Jang, H. T. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2018.05.181 · Cited by 77

Capecitabine lipid nanoparticles for anti-colon cancer activity in 1,2-dimethylhydrazine-induced colon cancer: preparation, cytotoxic, pharmacokinetic, and pathological evaluation

Dudhipala, N. R., & Puchchakayala, G. R. (2018) · Drug Development and Industrial Pharmacy · doi:10.1080/03639045.2018.1445264 · Cited by 74

Targeted delivery of capecitabine to colon cancer cells using nano polymeric micelles based on beta cyclodextrin

Ameli, H., & Alizadeh, N. (2022) · RSC Advances · doi:10.1039/d1ra07791k · Cited by 72

Supramolecular hybrids of carbon dots with doxorubicin: synthesis, stability and cellular trafficking

Sun, T., Zheng, M. J., Xie, Z., & Jing, X. (2016) · Materials Chemistry Frontiers · doi:10.1039/c6qm00042h · Cited by 67

Folic acid mediated synaphic delivery of doxorubicin using biogenic gold nanoparticles anchored to biological linkers

Pandey, S., Oza, G., Mewada, A., Shah, R., Thakur, M., & Sharon, M. (2013) · Journal of Materials Chemistry B · doi:10.1039/c2tb00168c · Cited by 58

Topical Silymarin Administration for Prevention of Capecitabine‐Induced Hand–Foot Syndrome: A Randomized, Double‐Blinded, Placebo‐Controlled Clinical Trial

Elyasi, S., Rezazadeh‐Shojaee, F., Allahyari, A., & Karimi, G. (2017) · Phytotherapy Research · doi:10.1002/ptr.5857 · Cited by 57

Fluorescent carbon dots as carriers for intracellular doxorubicin delivery and track

Duan, Q., Ma, Y., Che, M., Zhang, B., Zhang, Y., Li, Y., Zhang, W., & Sang, S. (2018) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2018.12.015 · Cited by 56

Intrinsic and selective activity of functionalized carbon nanotube/nanocellulose platforms against colon cancer cells

Gonzalez-Dominguez, J. M., Grasa, L., Frontiñán-Rubio, J., Abás, E., Dominguez‐Alfaro, A., Mesonero, J. E., Criado, A., & Ansón‐Casaos, A. (2022) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2022.112363 · Cited by 50

Dual-functional carbon dots–silver@zinc oxide nanocomposite: in vitro evaluation of cellular uptake and induction of apoptosis

Sachdev, A., Matai, I., & Gopinath, P. (2014) · Journal of Materials Chemistry B · doi:10.1039/c4tb02043j · Cited by 49

Influence of wettability and surface activity on release behavior of hydrophilic substances from lipid matrices

Koennings, S., Berié, A., Teßmar, J., Blunk, T., & Göpferich, A. M. (2007) · Journal of Controlled Release · doi:10.1016/j.jconrel.2007.02.008 · Cited by 40

Evaluation of Nanocarrier Targeted Drug Delivery of Capecitabine-PAMAM Dendrimer Complex in a Mice Colorectal Cancer Model.

Nabavizadeh, F., Fanaei, H., Imani, A., Vahedian, J., Amoli, F. A., Ghorbi, J., Sohanaki, H., Mohammadi, S. M., & Golchoobian, R. (2016) · PubMed · Cited by 34

In vivo study of poly (ethylene glycol)-poly (caprolactone)-modified folic acid nanocarriers as a pH responsive system for tumor-targeted co-delivery of tamoxifen and quercetin

Zamani, M., Kiyaseh, M., Rostamizadeh, K., Manjili, H. K., Fridoni, M., & Danafar, H. (2019) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2019.101283 · Cited by 34

Fluorescence mechanism of xylan-derived carbon dots: Toward investigation on excitation-related emission behaviors

Yang, P., Zhu, Z., Zhang, W., Zhang, T., Li, X., Luo, M., Chen, W., Chen, M., & Zhou, X. (2020) · Journal of Luminescence · doi:10.1016/j.jlumin.2020.117199 · Cited by 24

Eudragit encapsulated cationic poly (lactic-co-glycolic acid) nanoparticles in targeted delivery of capecitabine for augmented colon carcinoma therapy

Rajasree, P. H., Paul, W., Sharma, C. P., Osmani, R. A. M., Hani, U., & Srivastava, A. (2018) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2018.05.025 · Cited by 23

PRELIMINARY PHYTOCHEMICAL INVESTIGATION ON LEAVES OF BUCHANANIA LANZAN (CHIRONJI)

Mehta, S. K., Mukherjee, S., & Jaiprakash, B. (2010) · Cited by 14

Formulation, Characterization and In-vitro and In-vivo Evaluation of Capecitabine Loaded Niosomes

Patel, P., Barot, T. D., & Kulkarni, P. (2020) · Current Drug Delivery · doi:10.2174/1567201817666200214111815 · Cited by 14

Carbon Dots: Synthesis, Characterizations, and Recent Advancements in Biomedical, Optoelectronics, Sensing, and Catalysis Applications

Lamba, R., Yukta, Y., Mondal, J., Kumar, R., Pani, B., & Singh, B. (2024) · ACS Applied Bio Materials · doi:10.1021/acsabm.4c00004 · Cited by 119

The future of plant based green carbon dots as cancer Nanomedicine: From current progress to future Perspectives and beyond

Hong, H. J., Shati, A. A., Alfaifi, M. Y., Elbehairi, S. E. I., & Sasidharan, S. (2024) · Journal of Advanced Research · doi:10.1016/j.jare.2024.01.034 · Cited by 54

Prospects and challenges of synergistic effect of fluorescent carbon dots, liposomes and nanoliposomes for theragnostic applications

Faghihi, H., Mozafari, M. R., Bumrungpert, A., Parsaei, H., Taheri, S. V., Mardani, P., Dehkharghani, F. M., Pudza, M. Y., & Alavi, M. (2023) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2023.103614 · Cited by 27

Enhanced anticancer effect of Artemisia turcomanica extract in niosomal formulation on breast cancer cells: In-vitro study

Keshtmand, Z., Naimi, S. N., Piran, Z. K., Jafroodi, P. P., & Yaraki, M. T. (2023) · Nano-Structures & Nano-Objects · doi:10.1016/j.nanoso.2023.101030 · Cited by 20

Exploring the potential of quantum dots and plasmonic nanoparticles for imaging and phototherapy in colorectal neoplasia

Patil, J., & Bhattacharya, S. (2024) · Results in Chemistry · doi:10.1016/j.rechem.2024.101689 · Cited by 18

Folate‐Receptor‐Mediated Uptake of Carbon Dots as a pH‐Responsive Carrier for Chemotherapy

Dubey, N., Ramteke, S., Jain, N. K., Dutta, T., & Koner, A. L. (2022) · ChemistrySelect · doi:10.1002/slct.202201604 · Cited by 11

Folic Acid – Carbon Dots – Doxorubicin Nanoparticles as Cancer Theranostic

Tetteh, M. T. (2022) · Digital Commons - East Tennessee State University (East Tennessee State University)

Doxorubicin conjugated carbon dots as a drug delivery system for human breast cancer therapy

Kong, T., Hao, L., Wei, Y., Cai, X., & Zhu, B. (2018) · Cell Proliferation · doi:10.1111/cpr.12488 · Cited by 187

Amine-Rich Carbon Dots Synthesized from Kappa-Carrageenan and l -Lysine as a Dual Probe for Detection of Folic Acid and Tumor-Targeted Delivery of Therapeutics

Paul, P., Roy, H., Bhattacharjee, G., Baruah, N., & Kundu, L. M. (2024) · ACS Applied Bio Materials · doi:10.1021/acsabm.4c00678 · Cited by 16

Carbon dots-based nanocarrier system with intrinsic tumor targeting ability for cancer treatment

Yang, X., Wang, Y., Du, X., Xu, J., & Zhao, M. (2020) · Nano Express · doi:10.1088/2632-959x/abbf3c · Cited by 7