Cited by 224Neuroendocrine regulation and behaviorPrimate Behavior and EcologyChild and Animal Learning Development

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Rodent empathy and affective neuroscience

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Panksepp, Jules B., Lahvis, Garet P.·2011·Neuroscience & Biobehavioral Reviews

DOI 10.1016/j.neubiorev.2011.05.013PMC PMC3183383

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Abstract

In the past few years, several experimental studies have suggested that empathy occurs in the social lives of rodents. Thus, rodent behavioral models can now be developed to elucidate the mechanistic substrates of empathy at levels that have heretofore been unavailable. For example, the finding that mice from certain inbred strains express behavioral and physiological responses to conspecific distress, while others do not, underscores that the genetic underpinnings of empathy are specifiable and that they could be harnessed to develop new therapies for human psychosocial impairments. However, the advent of rodent models of empathy is met at the outset with a number of theoretical and semantic problems that are similar to those previously confronted by studies of empathy in humans. The distinct underlying components of empathy must be differentiated from one another and from lay usage of the term. The primary goal of this paper is to review a set of seminal studies that are directly relevant to developing a concept of empathy in rodents. We first consider some of the psychological phenomena that have been associated with empathy, and within this context, we consider the component processes, or endophenotypes of rodent empathy. We then review a series of recent experimental studies that demonstrate the capability of rodents to detect and respond to the affective state of their social partners. We focus primarily on experiments that examine how rodents share affective experiences of fear, but we also highlight how similar types of experimental paradigms can be utilized to evaluate the possibility that rodents share positive affective experiences. Taken together, these studies were inspired by Jaak Panksepp's theory that all mammals are capable of felt affective experiences.

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The expression of the emotions in man and animals.
Darwin, C. D. (1872) · J. Murray eBooks · doi:10.1037/10001-000 · Cited by 12,120
A Handbook of Child Psychology
(1932) · Nature · doi:10.1038/130331a0 · Cited by 10,133
Emotion circuits in the brain
LeDoux, J. E. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.155 · Cited by 8,444
Beliefs about beliefs: Representation and constraining function of wrong beliefs in young children's understanding of deception
Wimmer, H. (1983) · Cognition · doi:10.1016/0010-0277(83)90004-5 · Cited by 6,305
Empathy: its ultimate and proximate bases
Preston, S. D., & de Waal, F. B. M. (2002) · Behavioral and Brain Sciences · doi:10.1017/s0140525x02000018 · Cited by 4,126
Untitled work
(1998) · Cited by 4,012
Self-citation
Empathy for Pain Involves the Affective but not Sensory Components of Pain
Singer, T., Seymour, B., O'Doherty, J., Kaube, H., Dolan, R. J., & Frith, C. D. (2004) · Science · doi:10.1126/science.1093535 · Cited by 3,929
The functional architecture of human empathy
Decety, J., & Jackson, P. L. (2004) · Behavioral and Cognitive Neuroscience Reviews · doi:10.1177/1534582304267187 · Cited by 3,407 · cited 1×
“Modern theoretical developments in empathy research have centered on an approach that views the expression of empathy as the result of an interaction between several component processes, both affective and cognitive (Hoffman, 1987; Preston and de Waal, 2002; Decety and Jackson, 2004).”
Background
Putting the Altruism Back into Altruism: The Evolution of Empathy
de Waal, F. B. M. (2008) · Annual Review of Psychology · doi:10.1146/annurev.psych.59.103006.093625 · Cited by 2,483 · cited 1×
“Prompted in part by the research and writings of primatologist Franz de Waal, more principled and evolutionary based perspectives on empathy have emerged (de Waal, 2008).”
Background
Empathy: A Social Psychological Approach
Davis, M. H. (1994) · Choice Reviews Online · doi:10.5860/choice.34-2454 · Cited by 2,442

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Lipps, 1903, Einfühlung, innere Nachahmung, und Organepfindungen, Archiv für die gesamte Psychologie, 1, 185

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Items 101–200 of 223

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Authors: Panksepp, J. B., & Lahvis, G. P.
Affiliations: Oregon Health & Science University (US)
Corresponding author: Panksepp, Jules B.
Lahvis, Garet P.
ORCID: Lahvis, Garet P.
Venue: Neuroscience & Biobehavioral Reviews
Publisher: Elsevier BV
Published: 2011-10
Volume: 35
Issue: 9
Pages: 1864-1875
ISSN: 0149-7634 (ISSN-L)
DOI: 10.1016/j.neubiorev.2011.05.013
PMC: PMC3183383
OpenAlex: W2002401366
Cited by: 224
References: 86
Citations by year: 2026: 7 · 2025: 11 · 2024: 17 · 2023: 16 · 2022: 23 · 2021: 14 · 2020: 12 · 2019: 12 · 2018: 23 · 2017: 22 · 2016: 19 · 2015: 15 · 2014: 12 · 2013: 11 · 2012: 7
FWCI: 1.32
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Neuroscience & Biobehavioral Reviews (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: Eunice Kennedy Shriver National Institute of Child Health and Human Development (R03HD046716)
Topics: Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Primate Behavior and Ecology
Social Sciences › Psychology › Developmental and Educational Psychology › Child and Animal Learning Development
Keywords: empathy, rodents, affective neuroscience, inbred mouse strains, endophenotypes, positive affective states, Panksepp
MeSH terms: Affect, Animals, Empathy, Fear, Interpersonal Relations, Neurosciences, Pain, Rodentia, Social Behavior, Social Environment, Mice, Rats

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Rodent empathy and affective neuroscience

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