The DOI matches its Crossref record; 220 of the 225 references it cites were found in a registry or an index.
From psychological moments to mortality: A multidisciplinary synthesis on heart rate variability spanning the continuum of time
Abstract
Heart rate variability (HRV) indexes functioning of the vagus nerve, arguably the most important nerve in the human body. The Neurovisceral Integration Model has provided a structural framework for understanding brain-body integration, highlighting the role of the vagus in adaptation to the environment. In the present paper, we emphasise a temporal framework in which HRV may be considered a missing, structural link between psychological moments and mortality, a proposal we label as Neurovisceral Integration Across a Continuum of Time (or NIACT). This new framework places neurovisceral integration on a dimension of time, highlighting implications for lifespan development and healthy aging, and helping to bridge the gap between clearly demarcated disciplines such as psychology and epidemiology. The NIACT provides a novel framework, which conceptualizes how everyday psychological moments both affect and are affected by the vagus in ways that have long-term effects on mortality risk. We further emphasize that a longitudinal approach to understanding change in vagal function over time may yield novel scientific insights and important public health outcomes.
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“The focus on physiological data in the psychotherapeutic context is gaining traction20–22 and has strong theoretical underpinnings.23–25”
From A novel ACT-based video game to support mental health through embedded learning: A mixed-methods feasibility study protocol (2020) · cites this paper as [23]
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“Psychological distress increases morbidity from a host of conditions and increases risk for premature mortality in a dose–response relationship.2 3”
From Novel ACT-based eHealth psychoeducational intervention for students with mental distress: A study protocol for a mixed-methodology pilot trial (2019) · cites this paper as [2]
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Items 201–220 of 220
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Arias-López, J. A., Williams, C., Raghvani, R., Aghajani, M., Báez, S., Belzung, C., Booij, L., Busatto, G. F., Chiarella, J., Fu, C. H. Y., et al. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.01.006 · Cited by 138
Schmalenberger, K., Eisenlohr-Moul, T., Würth, L., Schneider, E., Thayer, J., Ditzen, B., & Jarczok, M. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8111946 · Cited by 104
Metadata
- Authors
- Kemp, A. H., Koenig, J., & Thayer, J. F.
- Affiliations
- The University of Sydney (AU)
- Heidelberg University (DE)
- The Ohio State University (US)
- Corresponding author
- Kemp, Andrew H.
- Thayer, Julian F.
- Venue
- Neuroscience & Biobehavioral Reviews
- Publisher
- Elsevier BV
- Published
- 2017-12
- Volume
- 83
- Pages
- 547-567
- ISSN
- 0149-7634 (ISSN-L)
- OpenAlex
- W2752326235
- Cited by
- 114
- References
- 225
- Citations by year
- 2026: 8 · 2025: 7 · 2024: 8 · 2023: 12 · 2022: 15 · 2021: 15 · 2020: 19 · 2019: 17 · 2018: 13
- FWCI
- 1.90
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuroscience & Biobehavioral Reviews (publishedVersion)
- PubMed (publishedVersion)
- Funders
- FAPESP (#2013/50327-6)
- Brazilian research funding institution
- Medical School of Heidelberg University
- Post-Doctoral Fellowship provided by the Daimler and Benz Foundation
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Life Sciences › Neuroscience › Neurology › Vagus Nerve Stimulation Research
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Keywords
- heart rate variability, vagus nerve, neurovisceral integration, mortality risk, lifespan development, healthy aging, temporal framework
- MeSH terms
- Aging, Animals, Heart Rate, Humans, Psychophysiology, Vagus Nerve, Health Behavior, Visceral Afferents
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