NGF-mediated sensitization of the excitability of rat sensory neurons is prevented by a blocking antibody to the p75 neurotrophin receptor

Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons.

Holzer, P. D. (1991) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06664-5 · Cited by 1,784 · see citing works

Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition

Chuang, H.-H., Prescott, E. D., Kong, H., Shields, S. D., Jordt, S. E., Basbaum, A. I., Chao, M. V., & Julius, D. J. (2001) · Nature · doi:10.1038/35082088 · Cited by 1,257 · see citing works

K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases

Kase, H., Iwahashi, K., Nakanishi, S., Matsuda, Y., Yamada, K., Takahashi, M., Murakata, C., Sato, A., & Kaneko, M. (1987) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(87)90293-2 · Cited by 939 · see citing works

Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity

Woolf, C. J., Safieh‐Garabedian, B., Ma, Q., Crilly, P. J., & Winter, J. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90366-2 · Cited by 695 · see citing works

Nerve growth factors (NGF, BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons

Lindsay, R. M. (1988) · Journal of Neuroscience · doi:10.1523/jneurosci.08-07-02394.1988 · Cited by 662 · see citing works

Nerve growth factor receptors. Characterization of two distinct classes of binding sites on chick embryo sensory ganglia cells.

Sutter, A., Rj, R., Harris‐Warrick, R. M., & Shooter, E. M. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50507-x · Cited by 624 · see citing works

Activation of the Sphingomyelin Cycle Through the Low-Affinity Neurotrophin Receptor

Dobrowsky, R. T., Werner, M. H., Castellino, A. M., Chao, M. V., & Hannun, Y. A. (1994) · Science · doi:10.1126/science.8079174 · Cited by 582 · see citing works

Nerve growth factor-induced hyperalgesia in the neonatal and adult rat

Lewin, G. R., Ritter, A., & Mendell, L. M. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-05-02136.1993 · Cited by 562 · see citing works

p75LNGFR regulates Trk signal transduction and NGF-induced neuronal differentiation in MAH cells

Verdi, J. M., Birren, S. J., Ibáñez, C. F., Persson, H., Kaplan, D. R., Benedetti, M., Chao, M. V., & Anderson, D. J. (1994) · Neuron · doi:10.1016/0896-6273(94)90327-1 · Cited by 345 · see citing works

Glutathione Regulation of Neutral Sphingomyelinase in Tumor Necrosis Factor-α-induced Cell Death

Liu, B., Andrieu‐Abadie, N., Levade, T., Zhang, P., Obeid, L. M., & Hannun, Y. A. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.18.11313 · Cited by 337 · see citing works

Inhibition of the Neutral Magnesium-dependent Sphingomyelinase by Glutathione

Liu, B., & Hannun, Y. A. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.26.16281 · Cited by 304 · see citing works

Evidence that biological activity of NGF is mediated through a novel subclass of high affinity receptors

Weskamp, G., & Reichardt, L. F. (1991) · Neuron · doi:10.1016/0896-6273(91)90067-a · Cited by 292 · see citing works

The low affinity NGF receptor, p75, can collaborate with each of the Trks to potentiate functional responses to the neurotrophins

Hantzopoulos, P. A., Suri, C., Glass, D. J., Goldfarb, M. P., & Yancopoulos, G. D. (1994) · Neuron · doi:10.1016/0896-6273(94)90469-3 · Cited by 284 · see citing works

Nerve growth factor acutely sensitizes the response of adult rat sensory neurons to capsaicin

Shu, X., & Mendell, L. M. (1999) · Neuroscience Letters · doi:10.1016/s0304-3940(99)00701-6 · Cited by 272 · see citing works

Neurotrophins and hyperalgesia

Shu, X.-Q., & Mendell, L. M. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.14.7693 · Cited by 266 · see citing works

Acute Sensitization by NGF of the Response of Small-Diameter Sensory Neurons to Capsaicin

Shu, X., & Mendell, L. M. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.86.6.2931 · Cited by 169 · see citing works

Ceramide, a putative second messenger for nerve growth factor, modulates the TTX‐resistant Na+ current and delayed rectifier K+ current in rat sensory neurons

Zhang, Y. H., Vasko, M. R., & Nicol, G. D. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2002.024265 · Cited by 157 · see citing works

Nerve growth factor NT-5 induce increased thermal sensitivity of cutaneous nociceptors in vitro

Rueff, A., & Mendell, L. M. (1996) · Journal of Neurophysiology · doi:10.1152/jn.1996.76.5.3593 · Cited by 98 · see citing works

Individual and Combined Effects of TrkA and p75NTR Nerve Growth Factor Receptors

Lad, S. P., Peterson, D. A., Bradshaw, R. A., & Neet, K. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m212270200 · Cited by 80 · see citing works

Brain-derived Neurotrophic Factor Binding to the p75 Neurotrophin Receptor Reduces TrkA Signaling While Increasing Serine Phosphorylation in the TrkA Intracellular Domain

MacPhee, I. J., & Barker, P. A. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.38.23547 · Cited by 78 · see citing works

Coupling of the p75 Neurotrophin Receptor to Sphingolipid Signalinga

Dobrowsky, R. T., & Carter, B. D. (1998) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1998.tb09660.x · Cited by 66 · see citing works

p75 Reduces TrkB Tyrosine Autophosphorylation in Response to Brain-derived Neurotrophic Factor and Neurotrophin 4/5

Vesa, J., Krüttgen, A., & Shooter, E. M. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m001641200 · Cited by 47 · see citing works

Differential cross-regulation of TrkA and TrkC tyrosine kinase receptors with p75

Ivanisevic, L., Banerjee, K., & Saragovi, H. U. (2003) · Oncogene · doi:10.1038/sj.onc.1206864 · Cited by 34 · see citing works

Prostaglandin e2 inhibits the potassium current in sensory neurons from hyperalgesic kv1.1 knockout mice

Jiang, X. Q., Zhang, Y. H., Clark, J. D., Tempel, B. L., & Nicol, G. D. (2003) · Neuroscience · doi:10.1016/s0306-4522(03)00073-3 · Cited by 30 · see citing works

Does NGF binding to p75 and trkA receptors activate independent signalling pathways to sensitize nociceptors?

Mendell, L. M. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2002.028662 · Cited by 9 · see citing works

Topical capsaicin for pain management: therapeutic potential and mechanisms of action of the new high-concentration capsaicin 8% patch

Anand, P., & Bley, K. R. (2011) · British Journal of Anaesthesia · doi:10.1093/bja/aer260 · Cited by 708 · see citing works

Immune and glial cell factors as pain mediators and modulators

McMahon, S. B., Cafferty, W. B. J., & Marchand, F. (2005) · Experimental Neurology · doi:10.1016/j.expneurol.2004.11.001 · Cited by 441 · see citing works

Novel class of pain drugs based on antagonism of NGF

Hefti, F. F., Rosenthal, A., Walicke, P. A., Wyatt, S. L., Vergara, G., Shelton, D. L., & Davies, A. M. (2005) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2005.12.001 · Cited by 380 · see citing works

The Role of Sodium Channels in Chronic Inflammatory and Neuropathic Pain

Amir, R., Argoff, C. E., Bennett, G. J., Cummins, T., Durieux, M. E., Gerner, P., Gold, M. S., Porreca, F., & Strichartz, G. R. (2006) · Journal of Pain · doi:10.1016/j.jpain.2006.01.444 · Cited by 360 · see citing works

Antagonism of Nerve Growth Factor-TrkA Signaling and the Relief of Pain

Mantyh, P. W., Koltzenburg, M., Mendell, L. M., Tive, L. A., Shelton, D. L., & Warner, D. S. (2011) · Anesthesiology · doi:10.1097/aln.0b013e31821b1ac5 · Cited by 330 · see citing works

Nerve Growth Factor Signaling and Its Contribution to Pain

Barker, P. A., Mantyh, P. W., Arendt‐Nielsen, L., Viktrup, L., & Tive, L. A. (2020) · Journal of Pain Research · doi:10.2147/jpr.s247472 · Cited by 283 · see citing works

Roles for dysfunctional sphingolipid metabolism in Alzheimer's disease neuropathogenesis

Haughey, N. J., Bandaru, V. V. R., Bae, M. H., & Mattson, M. P. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2010.05.003 · Cited by 271 · see citing works

Peripheral mechanisms of pain and analgesia

Stein, C., Clark, J. D., Oh, U., Vasko, M. R., Wilcox, G. L., Overland, A. C., Vanderah, T. W., & Spencer, R. H. (2009) · Brain Research Reviews · doi:10.1016/j.brainresrev.2008.12.017 · Cited by 268 · see citing works

Pain, mast cells, and nerves in peritoneal, ovarian, and deep infiltrating endometriosis

Anaf, V., Chapron, C., El Nakadi, I., De Moor, V., Simonart, T., & Noël, J.-C. (2006) · Fertility and Sterility · doi:10.1016/j.fertnstert.2006.03.057 · Cited by 258 · see citing works

Neurotrophins and Neuropathic Pain: Role in Pathobiology

Khan, N., & Smith, M. T. (2015) · Molecules · doi:10.3390/molecules200610657 · Cited by 199 · see citing works

The Development and Maintenance of Paclitaxel-induced Neuropathic Pain Require Activation of the Sphingosine 1-Phosphate Receptor Subtype 1

Janes, K., Little, J. W., Li, C., Bryant, L., Chen, C., Chen, Z., Kamocki, K., Doyle, T. M., Snider, A. J., Esposito, E., et al. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.569574 · Cited by 156 · see citing works

Unraveling the Story of NGF-mediated Sensitization of Nociceptive Sensory Neurons: ON or OFF the Trks?

Nicol, G. D., & Vasko, M. R. (2007) · Molecular Interventions · doi:10.1124/mi.7.1.6 · Cited by 145 · see citing works

Primary afferent nociceptor mechanisms mediating NGF‐induced mechanical hyperalgesia

Malik‐Hall, M., Dina, O. A., & Levine, J. D. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04173.x · Cited by 121 · see citing works

Mechanical and heat sensitization of cutaneous nociceptors in rats with experimental peripheral neuropathy

Shim, B., Kim, D.-W., Kim, B. H., Nam, T. S., Leem, J. W., & Chung, J. M. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2004.12.036 · Cited by 115 · see citing works

Nerve growth factor mediates hyperalgesia and cachexia in auto-immune arthritis

Shelton, D. L., Zeller, J., Ho, W.-H., Pons, J., & Rosenthal, A. (2005) · Pain · doi:10.1016/j.pain.2005.03.039 · Cited by 109 · see citing works

Inhibition of neutral sphingomyelinase‐2 perturbs brain sphingolipid balance and spatial memory in mice

Tabatadze, N., Savonenko, A. V., Song, H., Bandaru, V. V. R., Chu, M., & Haughey, N. J. (2010) · Journal of Neuroscience Research · doi:10.1002/jnr.22438 · Cited by 101 · see citing works

Taking Pain Out of NGF: A “Painless” NGF Mutant, Linked to Hereditary Sensory Autonomic Neuropathy Type V, with Full Neurotrophic Activity

Capsoni, S., Covaceuszach, S., Marinelli, S., Ceci, M., Bernardo, A., Minghetti, L., Ugolini, G., Pavone, F., & Cattaneo, A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017321 · Cited by 97 · see citing works

Nerve growth factor regulates substance P in adult sensory neurons through both TrkA and p75 receptors

Skoff, A. M., & Adler, J. E. (2005) · Experimental Neurology · doi:10.1016/j.expneurol.2005.10.006 · Cited by 88 · see citing works

Suppression of the p75 Neurotrophin Receptor in Uninjured Sensory Neurons Reduces Neuropathic Pain after Nerve Injury

Obata, K., Katsura, H., Sakùrai, J., Kobayashi, K., Yamanaka, H., Dai, Y., Fukuoka, T., & Noguchi, K. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3188-06.2006 · Cited by 87 · see citing works

The role of mast cells and their mediators in reproduction, pregnancy and labour

Menzies, F. M., Shepherd, M. C., Nibbs, R. J. B., & Nelson, S. M. (2010) · Human Reproduction Update · doi:10.1093/humupd/dmq053 · Cited by 87 · see citing works

New insights into the pathophysiology and treatment of chronic itch in patients with end‐stage renal disease, chronic liver disease, and lymphoma

Wang, H., & Yosipovitch, G. (2009) · International Journal of Dermatology · doi:10.1111/j.1365-4632.2009.04249.x · Cited by 86 · see citing works

Mirror-image pain is mediated by nerve growth factor produced from tumor necrosis factor alpha-activated satellite glia after peripheral nerve injury

Cheng, C.-F., Cheng, J., Chen, C.-Y., Lien, C., Chu, D., Wang, S.-Y., & Tsaur, M.-L. (2014) · Pain · doi:10.1016/j.pain.2014.01.010 · Cited by 81 · see citing works

Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system

Okada, T., Kajimoto, T., Jahangeer, S. M., & Nakamura, S. (2008) · Cellular Signalling · doi:10.1016/j.cellsig.2008.07.011 · Cited by 77 · see citing works

Intracellular sphingosine 1‐phosphate mediates the increased excitability produced by nerve growth factor in rat sensory neurons

Zhang, Y. H., Vasko, M. R., & Nicol, G. D. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.111575 · Cited by 73 · see citing works

Therapeutic targeting of the ceramide-to-sphingosine 1-phosphate pathway in pain

Salvemini, D., Doyle, T. M., Kress, M., & Nicol, G. D. (2013) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2012.12.001 · Cited by 69 · see citing works

Sensory Neurons, Ion Channels, Inflammation and the Onset of Neuropathic Pain

Stemkowski, P. L., & Smith, P. A. (2012) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/s0317167100013937 · Cited by 67 · see citing works

Sphingolipid control of cognitive functions in health and disease

Kalinichenko, L. S., Gulbins, E., Kornhuber, J., & Müller, C. P. (2022) · Progress in Lipid Research · doi:10.1016/j.plipres.2022.101162 · Cited by 64 · see citing works

The role of mast cells in the pathogenesis of pain in chronic pancreatitis

Hoogerwerf, W. A., Gondesen, K., Xiao, S.-Y., Winston, J. H., Willis, W. D., & Pasricha, P. J. (2005) · BMC Gastroenterology · doi:10.1186/1471-230x-5-8 · Cited by 61 · see citing works

Lipid mediators of sensitivity in sensory neurons

Park, K. A., & Vasko, M. R. (2005) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2005.09.010 · Cited by 61 · see citing works

Brain‐derived neurotrophic factor enhances the excitability of rat sensory neurons through activation of the p75 neurotrophin receptor and the sphingomyelin pathway

Zhang, Y. H., Chi, X. X., & Nicol, G. D. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2008.152439 · Cited by 59 · see citing works

In vitro receptor binding properties of a “painless” NGF mutein, linked to hereditary sensory autonomic neuropathy type V

Covaceuszach, S., Capsoni, S., Marinelli, S., Pavone, F., Ceci, M., Ugolini, G., Vignone, D., Amato, G., Paoletti, F., Lamba, D., et al. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.11.146 · Cited by 55 · see citing works

Excitability of Aβ sensory neurons is altered in an animal model of peripheral neuropathy

Zhu, Y. F., & Henry, J. L. (2012) · BMC Neuroscience · doi:10.1186/1471-2202-13-15 · Cited by 54 · see citing works

Neurotrophins and target interactions in the development and regulation of sympathetic neuron electrical and synaptic properties

Luther, J. A., & Birren, S. J. (2009) · Autonomic Neuroscience · doi:10.1016/j.autneu.2009.08.009 · Cited by 52 · see citing works

Targeting the Nerve Growth Factor (NGF) Pathway in Drug Discovery. Potential Applications to New Therapies for Chronic Pain

Norman, B. H., & McDermott, J. S. (2016) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.6b00964 · Cited by 52 · see citing works

Nerve fibers and endometriotic lesions: partners in crime in inflicting pains in women with endometriosis

Yan, D., Liu, X., & Guo, S. (2016) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2016.06.017 · Cited by 48 · see citing works

Nerve Growth Factor Regulates the Firing Patterns and Synaptic Composition of Motoneurons

de Carrizosa, M. A. D., Morado-Díaz, C. J., Morcuende, S., de la Cruz, R. R., & Pastor, Á. M. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.0719-10.2010 · Cited by 47 · see citing works

Pulmonary distribution, regulation, and functional role of Trk receptors in a murine model of asthma

Nassenstein, C., Dawbarn, D., POLLOCK, K., Allen, S. J., Erpenbeck, V. J., Spies, E., Krug, N., & Braun, A. C. (2006) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2006.04.052 · Cited by 47 · see citing works

The p75 neurotrophin receptor is essential for neuronal cell survival and improvement of functional recovery after spinal cord injury

Chu, G. K. T., Yu, W. R., & Fehlings, M. G. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.05.028 · Cited by 43 · see citing works

Swedish Nerve Growth Factor Mutation (NGF R100W ) Defines a Role for TrkA and p75 NTR in Nociception

Sung, K., Ferrari, L. F., Yang, W., Chung, C., Zhao, X., Gu, Y., Lin, S., Zhang, K., Cui, B., Pearn, M. L., et al. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.1686-17.2018 · Cited by 41 · see citing works

Neurogenic inflammation as a novel treatment target for chronic pain syndromes

Seidel, M. F., Hügle, T., Morlion, B. J., Koltzenburg, M., Chapman, V., MaassenVanDenBrink, A., Lane, N. E., Perrot, S., & Zieglgänsberger, W. (2022) · Experimental Neurology · doi:10.1016/j.expneurol.2022.114108 · Cited by 41 · see citing works

The p75NTR signaling cascade mediates mechanical hyperalgesia induced by nerve growth factor injected into the rat hind paw

Khodorova, A. B., Nicol, G. D., & Strichartz, G. R. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.09.046 · Cited by 40 · see citing works

From genes to pain: nerve growth factor and hereditary sensory and autonomic neuropathy type V

Capsoni, S. (2014) · European Journal of Neuroscience · doi:10.1111/ejn.12461 · Cited by 40 · see citing works

Differential Axonal Conduction Patterns of Mechano-Sensitive and Mechano-Insensitive Nociceptors – A Combined Experimental and Modelling Study

Petersson, M., Obreja, O., Lampert, A., Carr, R. W., Schmelz, M., & Fransén, E. A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0103556 · Cited by 39 · see citing works

Nerve growth factor enhances the excitability of rat sensory neurons through activation of the atypical protein kinase C isoform, PKMζ

Zhang, Y. H., Kays, J. S., Hodgdon, K. E., Sacktor, T. C., & Nicol, G. D. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00030.2011 · Cited by 37 · see citing works

NGF enhances electrically induced pain, but not axon reflex sweating

Obreja, O., Kluschina, O., Mayer, A., Hirth, M., Schley, M. T., Schmelz, M., & Rukwied, R. (2011) · Pain · doi:10.1016/j.pain.2011.04.002 · Cited by 35 · see citing works

Nerve growth factor enhances cough and airway obstruction via TrkA receptor- and TRPV1-dependent mechanisms

El‐Hashim, A. Z., & Jaffal, S. M. (2009) · Thorax · doi:10.1136/thx.2009.113183 · Cited by 34 · see citing works

Intraplantar‐injected ceramide in rats induces hyperalgesia through an NF‐κB‐ and p38 kinase‐dependent cyclooxygenase 2/prostaglandin E2 pathway

Doyle, T., Chen, Z., Muscoli, C., Obeid, L., & Salvemini, D. (2011) · The FASEB Journal · doi:10.1096/fj.10-178095 · Cited by 37 · see citing works

Inflammatory Pain Reduces C Fiber Activity-Dependent Slowing in a Sex-Dependent Manner, Amplifying Nociceptive Input to the Spinal Cord

Dickie, A. C., McCormick, B., Lukito, V., Wilson, K. L., & Torsney, C. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.3816-16.2017 · Cited by 33 · see citing works

The TrkA receptor mediates experimental thermal hyperalgesia produced by nerve growth factor: Modulation by the p75 neurotrophin receptor

Khodorova, A. B., Nicol, G. D., & Strichartz, G. R. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.10.064 · Cited by 31 · see citing works

Functional Diversity of Neurotrophin Actions on the Oculomotor System

Benítez‐Temiño, B., de Carrizosa, M. A. D., Morcuende, S., Matarredona, E. R., de la Cruz, R. R., & Pastor, Á. M. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17122016 · Cited by 31 · see citing works

Neural innervation in adipose tissue, gut, pancreas, and liver

Sun, M., Wan, Y., Shi, M., Meng, Z., & Zeng, W. (2023) · Life Metabolism · doi:10.1093/lifemeta/load022 · Cited by 28 · see citing works

Human nerve growth factor sensitizes masseter muscle nociceptors in female rats

Svensson, P. J., Wang, M. W., Dong, X., Kumar, U., & Cairns, B. E. (2010) · Pain · doi:10.1016/j.pain.2009.12.009 · Cited by 28 · see citing works

Effects of LNG-IUS on nerve growth factor and its receptors expression in patients with adenomyosis

Choi, Y. S., Cho, S., Lim, K. J., Jeon, Y. E., Yang, H. I., Lee, K. E., Heena, K., Seo, S. K., Kim, H. Y., & Lee, B. S. (2010) · Growth Factors · doi:10.3109/08977194.2010.511619 · Cited by 28 · see citing works

Systemic administration of anti-NGF increases A-type potassium currents and decreases pancreatic nociceptor excitability in a rat model of chronic pancreatitis

Zhu, Y., Mehta, K. R., Li, C., Xu, G., Liu, L., Colak, T., Shenoy, M. M., & Pasricha, P. J. (2011) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00053.2011 · Cited by 28 · see citing works

Lipid mediators regulating pain sensitivity

Malan, T. P., & Porreca, F. (2005) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2004.09.008 · Cited by 26 · see citing works

Review of Mechanisms, Pharmacological Management, Psychosocial Implications, and Holistic Treatment of Pain in Fabry Disease

Rajan, J. N., Ireland, K., Johnson, R., & Stępień, K. M. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10184168 · Cited by 25 · see citing works

Nerve growth factor-induced hyperexcitability of rat sensory neuron in culture

Kitamura, N., Konno, A., KUWAHARA, T., & Komagiri, Y. (2005) · Biomedical Research · doi:10.2220/biomedres.26.123 · Cited by 25 · see citing works

Brain‐derived neurotrophic factor modulates cell excitability in the mouse medial nucleus of the trapezoid body

Youssoufian, M., & Walmsley, B. D. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05428.x · Cited by 20 · see citing works

Molecular Biology of the Nociceptor/Transduction

Gold, M. S., & Caterina, M. J. (2008) · Elsevier eBooks · doi:10.1016/b978-012370880-9.00141-9 · Cited by 18 · see citing works

A Novel Alternative in the Treatment of Detrusor Overactivity? In Vivo Activity of O-1602, the Newly Synthesized Agonist of GPR55 and GPR18 Cannabinoid Receptors

Wróbel, A., Szopa, A., Serefko, A., & Poleszak, E. (2020) · Molecules · doi:10.3390/molecules25061384 · Cited by 16 · see citing works

Dysregulation of sphingolipid metabolism in pain

Wang, J., Zheng, G., Wang, L., Meng, L., Ren, J., Shang, L., Li, D., & Bao, Y. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1337150 · Cited by 14 · see citing works

Enhanced production and secretion of glial cell line-derived neurotrophic factor and nerve growth factor from the skin in atopic dermatitis mouse model

Tokime, K., Katoh‐Semba, R., Yamanaka, K., Mizoguchi, A., & Mizutani, H. (2008) · Archives of Dermatological Research · doi:10.1007/s00403-008-0856-z · Cited by 14 · see citing works

Nerve growth factor affects Ca2+ currents via the p75 receptor to enhance prolactin mRNA levels in GH3 rat pituitary cells

López‐Domínguez, A. M., Espinosa, J. L., Navarrete, A., Ávila, G., & Cota, G. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.110791 · Cited by 14 · see citing works

Peripheral Synthesis of an Atypical Protein Kinase C Mediates the Enhancement of Excitability and the Development of Mechanical Hyperalgesia Produced by Nerve Growth Factor

Kays, J. S., Zhang, Y. H., Khorodova, A., Strichartz, G. R., & Nicol, G. D. (2017) · Neuroscience · doi:10.1016/j.neuroscience.2017.12.030 · Cited by 13 · see citing works

The molecular interplay between endocannabinoid and neurotrophin signals in the nervous system and beyond

Keimpema, E., Hökfelt, T. G. M., Harkany, T., & Doherty, P. (2014) · European Journal of Neuroscience · doi:10.1111/ejn.12431 · Cited by 13 · see citing works

Nerve growth factor, sphingomyelins, and sensitization in sensory neurons.

Nicol, G. D. (2008) · PubMed · Cited by 13 · see citing works

Role of Nerve Growth Factor in Orofacial Pain

Mai, L., Huang, F. P., Zhu, X. M., He, H., & Fan, W. (2020) · Journal of Pain Research · doi:10.2147/jpr.s250030 · Cited by 12 · see citing works

A novel immunocompetent model of metastatic prostate cancer‐induced bone pain

Liu, Z., Murphy, S. F., Huang, J. H., Zhao, L., Hall, C. C., Schaeffer, A. J., Schaeffer, E. M., & Thumbikat, P. (2020) · The Prostate · doi:10.1002/pros.23993 · Cited by 11 · see citing works

Nerve growth factor/p75 neurotrophin receptor-mediated sensitization of rat sensory neurons depends on membrane cholesterol

Zhang, Y. H., Khanna, R., & Nicol, G. D. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.06.039 · Cited by 10 · see citing works

Role of Mechanoinsensitive Nociceptors in Painful Diabetic Peripheral Neuropathy

Nemenov, M. I., Singleton, J. R., & Premkumar, L. S. (2021) · Current Diabetes Reviews · doi:10.2174/1573399818666211208101555 · Cited by 7 · see citing works

A missense point mutation in nerve growth factor (NGFR100W) results in selective peripheral sensory neuropathy

Yang, W., Sung, K., Xu, W. L., Gómez-Rodríguez, M. J., Wu, A. C., Santos, S. A., Fang, S., Uber, R. K., Dong, S. X., Guillory, B. C., et al. (2020) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2020.101886 · Cited by 7 · see citing works

Fabry disease-associated globotriaosylceramide induces mechanical allodynia via activation of signaling through proNGF–p75NTR but not mature NGF–TrkA

Sugimoto, J., Satoyoshi, H., Takahata, K., & Muraoka, S. (2021) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2021.173882 · Cited by 6 · see citing works

Overactive urinary bladder: Targeting sensory pathways

Lecci, A., & Maggi, C. A. (2005) · Drug Discovery Today Therapeutic Strategies · doi:10.1016/j.ddstr.2005.05.007 · Cited by 5 · see citing works

Extraocular Motoneurons and Neurotrophism

Pastor, Á. M., Blumer, R., & de la Cruz, R. R. (2022) · Advances in neurobiology · doi:10.1007/978-3-031-07167-6_12 · Cited by 4 · see citing works

Overactive bladder syndrome pharmacotherapy: future treatment options

Wróbel, A. (2015) · Menopause Review/Przegląd Menopauzalny · doi:10.5114/pm.2015.56403 · Cited by 4 · see citing works

Electroacupuncture down-regulates the expressions of colonic NGF and NGFR in visceral hypersensitivity rats

Liu, Y., Wu, H., Wang, X., Shi, Z., Jiang, Y., Song, C., Zhang, Y., & Tan, L.-Y. (2015) · Journal of Acupuncture and Tuina Science · doi:10.1007/s11726-015-0826-x · Cited by 3 · see citing works

Interactions of Peripheral Endothelin-1 and Nerve Growth Factor as Contributors to Persistent Cutaneous Pain

Khodorova, A. B., Zhang, Y. H., Nicol, G. D., & Strichartz, G. R. (2018) · Physiological Research · doi:10.33549/physiolres.933819 · Cited by 3 · see citing works

Molecular Biology of the Nociceptor/Transduction

Gold, M. S., & Stucky, C. L. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-809324-5.24215-6 · Cited by 1 · see citing works

Neurotrophins and Pain

Mendell, L. M. (2008) · Elsevier eBooks · doi:10.1016/b978-012370880-9.00161-4 · Cited by 1 · see citing works

RET-DEPENDENT AND RET-INDEPENDENT MECHANISMS OF GFL-INDUCED ENHANCEMENT IN THE CAPSAICIN STIMULATED-RELEASE OF iCGRP FROM SENSORY NEURONS

Schmutzler, B. S. (2010) · IUScholarWorks (Indiana University) · doi:10.7912/c2/288

Cellular Mechanisms Mediating the Actions of Nerve Growth Factor in Sensory Neurons

Park, K. A. (2007) · IUScholarWorks (Indiana University) · doi:10.7912/c2/281

NEUROFIBROMIN, NERVE GROWTH FACTOR AND RAS: THEIR ROLES IN CONTROLLING THE EXCITABILITY OF MOUSE SENSORY NEURONS

Wang, Y. (2007) · IUScholarWorks (Indiana University) · doi:10.7912/c2/279

Researches on Application of Stem Cell Therapy in Exercise-Induced Spinal Cord Injury Recovery

Qu, H., & Liu, R. (2011) · Advances in intelligent and soft computing · doi:10.1007/978-3-642-25538-0_15

Nociceptors via Protein Kinase C Sensory Nerve Terminal Mitochondrial Dysfunction Induces Hyperexcitability in Airway

Kays, J. S., Hodgdon, K. E., Sacktor, T. C., Nicol, G. D., Strey, K. A., Nichols, N. L., Baertsch, N. A., Broytman, O., Tracy, L. M., Hadley, S. H., et al. (2015)

Optic nerve regeneration in adult rat

Hu, Y. (2006) · UWA Profiles and Research Repository (UWA)

Interleukin (IL)-1 regulates ozone-induced nerve growth factor (NGF) and substance P (SP) release in bronchoalveolar lavage fluid (BALF) in mice

Barker, J. S. (2009) · doi:10.33915/etd.2813

Modulation of activity-dependent excitability changes in subclasses of primary afferent nociceptors

Jonas, R. (2024) · doi:10.33612/diss.870583559

Etude in vitro des mécanismes impliqués dans les effets sensoriels des ciguatoxines et brévétoxines - Focus sur la signalisation de PAR2

Pierre, O. (2019) · doi:10.70675/a7bd2e0bz23f5z4e07zaa0czd51f3b9890fd

BindingDB Entry 50047931: Targeting the Nerve Growth Factor (NGF) Pathway in Drug Discovery. Potential Applications to New Therapies for Chronic Pain.

BindingDB (2018) · UC San Diego · doi:10.7270/q2c24zcr

Does NGF binding to p75 and trkA receptors activate independent signalling pathways to sensitize nociceptors?

Mendell, L. M. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2002.028662 · Cited by 9 · see citing works

Nerve growth factor, sphingomyelins, and sensitization in sensory neurons.

Nicol, G. D. (2008) · PubMed · Cited by 13 · see citing works

The effects of melatonin on humoral immune responses of young and aged rats

AKBULUT, K. G., Gönül, B., & Akbulut, H. (1998) · Pathophysiology · doi:10.1016/s0928-4680(98)80856-0

The p75NTR signaling cascade mediates mechanical hyperalgesia induced by nerve growth factor injected into the rat hind paw

Khodorova, A. B., Nicol, G. D., & Strichartz, G. R. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.09.046 · Cited by 40 · see citing works

Neurotrophins and hyperalgesia

Shu, X.-Q., & Mendell, L. M. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.14.7693 · Cited by 266 · see citing works